UA91057C2 - Олигонуклеотид или его функциональный гомолог, композиция, содержащая его, и способ лечения в-клеточной опухоли - Google Patents
Олигонуклеотид или его функциональный гомолог, композиция, содержащая его, и способ лечения в-клеточной опухолиInfo
- Publication number
- UA91057C2 UA91057C2 UAA200714103A UAA200714103A UA91057C2 UA 91057 C2 UA91057 C2 UA 91057C2 UA A200714103 A UAA200714103 A UA A200714103A UA A200714103 A UAA200714103 A UA A200714103A UA 91057 C2 UA91057 C2 UA 91057C2
- Authority
- UA
- Ukraine
- Prior art keywords
- oligonucleotide
- composition
- treating
- same
- functional homologue
- Prior art date
Links
Classifications
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/117—Nucleic acids having immunomodulatory properties, e.g. containing CpG-motifs
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7088—Compounds having three or more nucleosides or nucleotides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H21/00—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
- C07H21/04—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids with deoxyribosyl as saccharide radical
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2310/00—Structure or type of the nucleic acid
- C12N2310/10—Type of nucleic acid
- C12N2310/17—Immunomodulatory nucleic acids
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2310/00—Structure or type of the nucleic acid
- C12N2310/30—Chemical structure
- C12N2310/31—Chemical structure of the backbone
- C12N2310/313—Phosphorodithioates
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2310/00—Structure or type of the nucleic acid
- C12N2310/30—Chemical structure
- C12N2310/31—Chemical structure of the backbone
- C12N2310/315—Phosphorothioates
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Genetics & Genomics (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Molecular Biology (AREA)
- Biotechnology (AREA)
- Wood Science & Technology (AREA)
- General Engineering & Computer Science (AREA)
- Zoology (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Biochemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Immunology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Physics & Mathematics (AREA)
- Biophysics (AREA)
- Microbiology (AREA)
- Plant Pathology (AREA)
- Epidemiology (AREA)
- Hematology (AREA)
- Oncology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Saccharide Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2005100695764A CN1865275B (zh) | 2005-05-17 | 2005-05-17 | 对人b细胞肿瘤有治疗作用的人工合成的单链脱氧核苷酸 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| UA91057C2 true UA91057C2 (ru) | 2010-06-25 |
Family
ID=37424439
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| UAA200714106A UA94231C2 (ru) | 2005-05-17 | 2006-02-13 | Олигонуклеотиды или их функциональные гомологи, композиция, которая содержит их, и способ лечения в-клеточной опухоли |
| UAA200714103A UA91057C2 (ru) | 2005-05-17 | 2006-02-13 | Олигонуклеотид или его функциональный гомолог, композиция, содержащая его, и способ лечения в-клеточной опухоли |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| UAA200714106A UA94231C2 (ru) | 2005-05-17 | 2006-02-13 | Олигонуклеотиды или их функциональные гомологи, композиция, которая содержит их, и способ лечения в-клеточной опухоли |
Country Status (22)
| Country | Link |
|---|---|
| US (3) | US8133874B2 (ru) |
| EP (2) | EP1883411B1 (ru) |
| JP (2) | JP4837034B2 (ru) |
| KR (2) | KR101346716B1 (ru) |
| CN (1) | CN1865275B (ru) |
| AU (2) | AU2006246897B2 (ru) |
| BR (2) | BRPI0609882A2 (ru) |
| CA (2) | CA2609062C (ru) |
| CY (1) | CY1114844T1 (ru) |
| DK (2) | DK1883411T3 (ru) |
| ES (2) | ES2433129T3 (ru) |
| HK (2) | HK1112745A1 (ru) |
| IL (2) | IL187281A (ru) |
| MX (2) | MX2007014146A (ru) |
| NZ (1) | NZ563582A (ru) |
| PL (2) | PL1883647T3 (ru) |
| PT (2) | PT1883647E (ru) |
| RU (2) | RU2413519C2 (ru) |
| SI (2) | SI1883647T1 (ru) |
| UA (2) | UA94231C2 (ru) |
| WO (2) | WO2006122463A1 (ru) |
| ZA (2) | ZA200710311B (ru) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2009260907A1 (en) * | 2008-06-18 | 2009-12-23 | Index Pharmaceuticals Ab | Combination therapies against cancer |
| CN101643496B (zh) * | 2008-08-07 | 2015-09-09 | 长春华普生物技术有限公司 | 一种具有免疫抑制功能的寡核苷酸 |
| EP2350282A1 (en) * | 2008-11-04 | 2011-08-03 | Index Pharmaceuticals AB | Increased expression of specific antigens |
| WO2012084991A1 (en) * | 2010-12-21 | 2012-06-28 | Index Pharmaceuticals Ab | Biologically active oligonucleotides capable of modulating the immune system ii |
| EP3165607B1 (en) * | 2010-12-21 | 2021-04-07 | InDex Pharmaceuticals AB | Biologically active oligonucleotides capable of modulating the immune system |
| CN106893724B (zh) * | 2015-12-17 | 2023-05-02 | 苏州派动生物技术有限公司 | 具有抗原增效作用和肿瘤治疗作用的寡核苷酸 |
| WO2021249116A1 (en) | 2020-06-10 | 2021-12-16 | Sichuan Clover Biopharmaceuticals, Inc. | Coronavirus vaccine compositions, methods, and uses thereof |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| MXPA02003108A (es) | 1999-09-25 | 2003-10-14 | Univ Iowa Res Found | Acidos nucleicos inmunoestimuladores. |
| CN1981868A (zh) * | 2000-03-31 | 2007-06-20 | 拜奥根Idec公司 | 抗细胞因子抗体或拮抗剂与抗－cd20在b细胞淋巴瘤治疗中的联合应用 |
| CA2410371C (en) * | 2000-06-22 | 2015-11-17 | University Of Iowa Research Foundation | Methods for enhancing antibody-induced cell lysis and treating cancer |
| US20040009156A1 (en) * | 2001-10-12 | 2004-01-15 | Christoph Reinhard | Antisense therapy using oligonucleotides that target human kinesin genes for treatment of cancer |
| JP2005516917A (ja) | 2001-12-12 | 2005-06-09 | アメリカ合衆国 | 細胞外アデノシン阻害剤およびアデノシン受容体阻害剤を用いて免疫応答および炎症を増強するための方法 |
| US7576066B2 (en) * | 2002-07-03 | 2009-08-18 | Coley Pharmaceutical Group, Inc. | Nucleic acid compositions for stimulating immune responses |
| DE10258677A1 (de) | 2002-12-13 | 2004-06-24 | Elez, Vera, Dr. | Kombinations-antisense-Oligonukleotid-Krebstherapie |
| CN100486987C (zh) * | 2003-03-05 | 2009-05-13 | 长春华普生物技术有限公司 | 抗病毒和抗肿瘤的含CpG单链脱氧寡核苷酸 |
| CN100439386C (zh) | 2003-03-05 | 2008-12-03 | 长春华普生物技术有限公司 | 增强蛋白类疫苗免疫效果的含CpG单链脱氧寡核苷酸 |
| EP1650218B1 (en) | 2003-07-25 | 2011-03-23 | Changchun Huapu Biotechnology Co., Ltd. | The artificial cpg single strand deoxidation oligonucleotide and its antiviral uses |
| JP4513879B2 (ja) | 2008-03-05 | 2010-07-28 | ソニー株式会社 | 像ぶれ補正装置、レンズ鏡筒装置及びカメラ装置 |
-
2005
- 2005-05-17 CN CN2005100695764A patent/CN1865275B/zh active Active
-
2006
- 2006-02-13 ES ES06705637T patent/ES2433129T3/es active Active
- 2006-02-13 DK DK06705637.4T patent/DK1883411T3/da active
- 2006-02-13 ES ES06705636.6T patent/ES2442462T3/es active Active
- 2006-02-13 AU AU2006246897A patent/AU2006246897B2/en not_active Ceased
- 2006-02-13 KR KR1020077028065A patent/KR101346716B1/ko not_active IP Right Cessation
- 2006-02-13 KR KR1020077028308A patent/KR101294131B1/ko not_active IP Right Cessation
- 2006-02-13 WO PCT/CN2006/000215 patent/WO2006122463A1/en active Application Filing
- 2006-02-13 ZA ZA200710311A patent/ZA200710311B/xx unknown
- 2006-02-13 PL PL06705636T patent/PL1883647T3/pl unknown
- 2006-02-13 ZA ZA200710312A patent/ZA200710312B/xx unknown
- 2006-02-13 SI SI200631728T patent/SI1883647T1/sl unknown
- 2006-02-13 BR BRPI0609882-7A patent/BRPI0609882A2/pt not_active IP Right Cessation
- 2006-02-13 MX MX2007014146A patent/MX2007014146A/es active IP Right Grant
- 2006-02-13 RU RU2007146705/14A patent/RU2413519C2/ru not_active IP Right Cessation
- 2006-02-13 UA UAA200714106A patent/UA94231C2/ru unknown
- 2006-02-13 US US11/914,745 patent/US8133874B2/en active Active
- 2006-02-13 CA CA2609062A patent/CA2609062C/en not_active Expired - Fee Related
- 2006-02-13 JP JP2008511532A patent/JP4837034B2/ja active Active
- 2006-02-13 MX MX2007014145A patent/MX2007014145A/es active IP Right Grant
- 2006-02-13 RU RU2007146706/10A patent/RU2409672C2/ru not_active IP Right Cessation
- 2006-02-13 DK DK06705636.6T patent/DK1883647T3/da active
- 2006-02-13 PT PT67056366T patent/PT1883647E/pt unknown
- 2006-02-13 EP EP06705637.4A patent/EP1883411B1/en active Active
- 2006-02-13 BR BRPI0609885-1A patent/BRPI0609885A2/pt not_active IP Right Cessation
- 2006-02-13 JP JP2008511531A patent/JP4837033B2/ja not_active Expired - Fee Related
- 2006-02-13 US US11/914,744 patent/US20090202567A1/en not_active Abandoned
- 2006-02-13 EP EP06705636.6A patent/EP1883647B1/en not_active Not-in-force
- 2006-02-13 WO PCT/CN2006/000216 patent/WO2006122464A1/en active Application Filing
- 2006-02-13 CA CA002609067A patent/CA2609067A1/en not_active Abandoned
- 2006-02-13 PT PT67056374T patent/PT1883411E/pt unknown
- 2006-02-13 NZ NZ563582A patent/NZ563582A/en not_active IP Right Cessation
- 2006-02-13 SI SI200631687T patent/SI1883411T1/sl unknown
- 2006-02-13 UA UAA200714103A patent/UA91057C2/ru unknown
- 2006-02-13 AU AU2006246898A patent/AU2006246898B2/en not_active Ceased
- 2006-02-13 PL PL06705637T patent/PL1883411T3/pl unknown
-
2007
- 2007-11-08 IL IL187281A patent/IL187281A/en not_active IP Right Cessation
- 2007-11-08 IL IL187249A patent/IL187249A/en not_active IP Right Cessation
-
2008
- 2008-07-28 HK HK08108303.7A patent/HK1112745A1/xx not_active IP Right Cessation
- 2008-07-28 HK HK08108302.8A patent/HK1113318A1/xx not_active IP Right Cessation
-
2011
- 2011-12-02 US US13/310,595 patent/US8450292B2/en not_active Expired - Fee Related
-
2014
- 2014-01-13 CY CY20141100024T patent/CY1114844T1/el unknown
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