JO3286B1 - متراكبات مائية من حديد و كربوهيدرات,انتاجها و ادوية تحتوي عليها - Google Patents
متراكبات مائية من حديد و كربوهيدرات,انتاجها و ادوية تحتوي عليهاInfo
- Publication number
- JO3286B1 JO3286B1 JOP/2003/0130A JOP20030130A JO3286B1 JO 3286 B1 JO3286 B1 JO 3286B1 JO P20030130 A JOP20030130 A JO P20030130A JO 3286 B1 JO3286 B1 JO 3286B1
- Authority
- JO
- Jordan
- Prior art keywords
- production
- medicaments containing
- iron carbohydrate
- aqueous iron
- carbohydrate complexes
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
- C08B31/00—Preparation of derivatives of starch
- C08B31/18—Oxidised starch
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
- C08B30/00—Preparation of starch, degraded or non-chemically modified starch, amylose, or amylopectin
- C08B30/12—Degraded, destructured or non-chemically modified starch, e.g. mechanically, enzymatically or by irradiation; Bleaching of starch
- C08B30/18—Dextrin, e.g. yellow canari, white dextrin, amylodextrin or maltodextrin; Methods of depolymerisation, e.g. by irradiation or mechanically
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/28—Compounds containing heavy metals
- A61K31/295—Iron group metal compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
- A61K31/716—Glucans
- A61K31/718—Starch or degraded starch, e.g. amylose, amylopectin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
- A61K33/24—Heavy metals; Compounds thereof
- A61K33/26—Iron; Compounds thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/56—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule
- A61K47/61—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule the organic macromolecular compound being a polysaccharide or a derivative thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/06—Antianaemics
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H23/00—Compounds containing boron, silicon, or a metal, e.g. chelates, vitamin B12
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
- C08B31/00—Preparation of derivatives of starch
- C08B31/18—Oxidised starch
- C08B31/185—Derivatives of oxidised starch, e.g. crosslinked oxidised starch
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
- C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
- C08B37/0006—Homoglycans, i.e. polysaccharides having a main chain consisting of one single sugar, e.g. colominic acid
- C08B37/0009—Homoglycans, i.e. polysaccharides having a main chain consisting of one single sugar, e.g. colominic acid alpha-D-Glucans, e.g. polydextrose, alternan, glycogen; (alpha-1,4)(alpha-1,6)-D-Glucans; (alpha-1,3)(alpha-1,4)-D-Glucans, e.g. isolichenan or nigeran; (alpha-1,4)-D-Glucans; (alpha-1,3)-D-Glucans, e.g. pseudonigeran; Derivatives thereof
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Epidemiology (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biochemistry (AREA)
- Polymers & Plastics (AREA)
- Materials Engineering (AREA)
- Molecular Biology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Crystallography & Structural Chemistry (AREA)
- Inorganic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Hematology (AREA)
- Diabetes (AREA)
- Biotechnology (AREA)
- Genetics & Genomics (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Polysaccharides And Polysaccharide Derivatives (AREA)
- Medicinal Preparation (AREA)
Abstract
يتعلق الاختراع الراهن بمتراكب قابل للذوبان في الماء من حديد وكربوهيدرات يمكن الحصول عليه من محلول مائي لملح الحديد( III) ومحلول مائي للمنتج الناتج عن اكسدة مركب مالتودكسترون واحد او اكثر له مكافيء دكستروز يتراوح من 5 الى 22 باستخدام محلول هيبوكلوريت مائي عند درجة حموضة تتراوح من 8.5 الى 12 ويتعلق الاختراع الراهن بعملية لانتاجه وبدواء لمعالجة حالات مرضية ناشئة عن نقص الحديد.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE10249552A DE10249552A1 (de) | 2002-10-23 | 2002-10-23 | Wasserlösliche Eisen-Kohlenhydrat-Komplexe, deren Herstellung und diese enthaltende Arzneimittel |
Publications (1)
Publication Number | Publication Date |
---|---|
JO3286B1 true JO3286B1 (ar) | 2018-09-16 |
Family
ID=32102937
Family Applications (3)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JOP/2003/0130A JO3286B1 (ar) | 2002-10-23 | 2003-10-02 | متراكبات مائية من حديد و كربوهيدرات,انتاجها و ادوية تحتوي عليها |
JOP/2011/0173A JOP20110173B1 (ar) | 2002-10-23 | 2011-05-26 | متراكبات قابلة للذوبان في الماء من حديد وكربوهيدرات، إنتاجها وأدوية تحتوي عليها |
JOP/2018/0046A JOP20180046B1 (ar) | 2002-10-23 | 2018-05-02 | متراكبات قابلة للذوبان في الماء من حديد وكربوهيدرات، إنتاجها وأدوية تحتوي عليها |
Family Applications After (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JOP/2011/0173A JOP20110173B1 (ar) | 2002-10-23 | 2011-05-26 | متراكبات قابلة للذوبان في الماء من حديد وكربوهيدرات، إنتاجها وأدوية تحتوي عليها |
JOP/2018/0046A JOP20180046B1 (ar) | 2002-10-23 | 2018-05-02 | متراكبات قابلة للذوبان في الماء من حديد وكربوهيدرات، إنتاجها وأدوية تحتوي عليها |
Country Status (30)
Country | Link |
---|---|
US (11) | US7612109B2 (ar) |
EP (2) | EP1554315B1 (ar) |
JP (2) | JP4777653B2 (ar) |
KR (1) | KR100992178B1 (ar) |
CN (1) | CN100480275C (ar) |
AR (1) | AR041472A1 (ar) |
AT (1) | ATE507246T1 (ar) |
AU (1) | AU2003278111C1 (ar) |
BR (2) | BRPI0315452B8 (ar) |
CA (1) | CA2493806C (ar) |
CY (2) | CY1112680T1 (ar) |
DE (2) | DE10249552A1 (ar) |
DK (2) | DK1554315T3 (ar) |
ES (2) | ES2364136T3 (ar) |
HK (2) | HK1081976A1 (ar) |
IL (1) | IL166747A (ar) |
JO (3) | JO3286B1 (ar) |
MX (1) | MXPA05004300A (ar) |
MY (1) | MY134394A (ar) |
NO (2) | NO333008B1 (ar) |
NZ (1) | NZ539243A (ar) |
PE (1) | PE20040571A1 (ar) |
PT (2) | PT1554315E (ar) |
RU (1) | RU2303039C2 (ar) |
SA (1) | SA03240447B1 (ar) |
SI (2) | SI1554315T1 (ar) |
TW (1) | TWI265028B (ar) |
UY (1) | UY28033A1 (ar) |
WO (1) | WO2004037865A1 (ar) |
ZA (1) | ZA200504174B (ar) |
Families Citing this family (44)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6757848B2 (en) | 2001-06-19 | 2004-06-29 | Hewlett-Packard Development Company, L.P. | Recovery of user data from partially incorrect data set in tape data storage system |
DE10249552A1 (de) | 2002-10-23 | 2004-05-13 | Vifor (International) Ag | Wasserlösliche Eisen-Kohlenhydrat-Komplexe, deren Herstellung und diese enthaltende Arzneimittel |
DE102004031181A1 (de) * | 2004-06-28 | 2006-01-19 | Vifor (International) Ag | Phosphatadsorbens |
RU2359680C2 (ru) * | 2005-02-09 | 2009-06-27 | Вифор (Интернациональ) Аг | Применение комплексных соединений железа (iii) |
ITMO20050056A1 (it) | 2005-03-15 | 2006-09-16 | Biofer Spa | Processo per la preparazione di complessi del ferro trivalente con zuccheri mono-, di- e polisaccaridi. |
EP1757299A1 (de) * | 2005-08-25 | 2007-02-28 | Vifor (International) Ag | Eisen(III)-Komplexverbindungen zur Behandlung von Eisenmangel-Zuständen bei Patienten mit chronisch-entzündlicher Darmerkrankung |
EP1790356A1 (de) * | 2005-11-24 | 2007-05-30 | Vifor (International) Ag | Präparat, umfassend Eisen(III)-Komplexverbindungen und redoxaktive Substanz(en) |
AU2013206429B2 (en) * | 2006-01-06 | 2016-04-28 | Vifor (International) Ag | Methods and compositions for administration of iron |
AU2016205002C1 (en) * | 2006-01-06 | 2020-09-24 | Vifor (International) Ag | Methods and compositions for administration of iron |
EP3081219A1 (en) | 2006-01-06 | 2016-10-19 | Luitpold Pharmaceuticals, Inc. | Methods and compositions for administration of iron |
EP1941869A1 (en) * | 2007-01-04 | 2008-07-09 | Vifor (International) Ag | Multicompartment bag for storage of iron preparations |
EP1947120A1 (de) * | 2007-01-19 | 2008-07-23 | Vifor (International) Ag | Eisen-Kohlenhydrat-Komplex-Verbindungen |
MX2009008281A (es) * | 2007-02-06 | 2009-08-25 | Medical Res Council | Materiales de ion metalico de poli-oxo-hidroxi modificados con ligando, sus usos y procesos para su preparacion. |
EP1997833A1 (de) * | 2007-05-29 | 2008-12-03 | Vifor (International) Ag | Wasserlösliche Eisen-Kohlenhydratderivat-Komplexe, deren Herstellung und diese enthaltende Arzneimittel |
BRPI0924653B8 (pt) | 2009-03-25 | 2021-05-25 | Pharmacosmos Holding As | composto de ferro-oligossacarídeo, composição e uso de deste composto |
WO2011055374A2 (en) * | 2009-11-04 | 2011-05-12 | Symed Labs Limited | Process for the preparation of iron (iii) carboxymaltose complex |
PE20130246A1 (es) | 2010-03-23 | 2013-04-07 | Vifor Int Ag | COMPUESTOS DEL COMPLEJO DE Fe(III) PARA EL TRATAMIENTO Y PROFILAXIS DE LOS SINTOMAS DE DEFICIENCIA DE HIERRO Y LAS ANEMIAS POR DEFICIENCIA DE HIERRO |
WO2012104204A1 (en) | 2011-01-31 | 2012-08-09 | Vifor (International) Ag | Iron-carbohydrate complex compounds for the intravenous therapy of malaria |
US9370202B2 (en) | 2013-03-15 | 2016-06-21 | LG Bionano, LLC | Encapsulated metal ion nanoclusters |
US9384629B2 (en) | 2014-03-31 | 2016-07-05 | Fresh Idea Global Limited | Automated money laundering detection, notification, and reporting techniques implemented at casino gaming networks |
EP3157516A4 (en) | 2014-06-22 | 2017-12-13 | Dexcel Pharma Technologies Ltd. | Pharmaceutical compositions comprising ferric citrate and methods for the production thereof |
EP2997968A1 (en) | 2014-09-22 | 2016-03-23 | Ioulia Tseti | Iron (III) hydroxide complexes with activated glucose syrups and process for preparing same |
CN104402984B (zh) * | 2014-11-11 | 2018-09-07 | 武汉科福新药有限责任公司 | 一种高载铁量的蛋白琥珀酸铁的制备方法 |
WO2016151367A1 (en) * | 2015-03-23 | 2016-09-29 | Suven Life Sciences Limited | Preparation of water soluble trivalent iron carbohydrate complexes |
WO2016181195A1 (en) * | 2015-05-08 | 2016-11-17 | Suven Life Sciences Limited | Improved process for water soluble iron carbohydrate complexes |
US20180147234A1 (en) * | 2015-05-29 | 2018-05-31 | Luitpold Pharmaceuticals, Inc. | Compositions and methods for treatment of fibromyalgia |
CN105125578B (zh) * | 2015-07-29 | 2018-05-11 | 南京生命能科技开发有限公司 | 一种具有高溶解速度的糖-铁复合物及其制备方法 |
CN105125577B (zh) * | 2015-07-29 | 2018-05-18 | 南京生命能科技开发有限公司 | 一种稳定的糖-铁复合物及其制备方法 |
US10258647B2 (en) * | 2015-09-01 | 2019-04-16 | Particle Dynamics International, Llc | Iron-polysaccharide complexes and methods for the preparation thereof |
GB201517893D0 (en) | 2015-10-09 | 2015-11-25 | Medical Res Council | Methods for producing carboxylate ligand modified ferric iron hydroxide colloids |
CN105520955B (zh) * | 2015-12-21 | 2018-05-11 | 南京生命能科技开发有限公司 | 一种羧基麦芽糖铁药用组合物及其制备方法 |
CN108129582A (zh) * | 2016-12-01 | 2018-06-08 | 江苏奥赛康药业股份有限公司 | 一种铁碳水化合物复合物的制备方法 |
EP3339329A1 (en) | 2016-12-22 | 2018-06-27 | LEK Pharmaceuticals d.d. | Selective oxidation of maltodextrin and its use in the preparation of water-soluble iron (iii) carboxymaltose complexes |
MX2020002527A (es) | 2017-09-11 | 2020-10-12 | Pharmacosmos Holding As | Compuestos de complejo de hierro para uso terapeutico. |
US20210155651A1 (en) * | 2018-04-05 | 2021-05-27 | Msn Laboratories Private Limited, R&D Center | Process for the preparation of iron (iii) carboxymaltose |
CN108498539A (zh) * | 2018-05-03 | 2018-09-07 | 东营天东制药有限公司 | 一种水溶性铁剂复合体原料药的制备方法 |
BR112021008142A2 (pt) | 2018-10-29 | 2021-08-03 | Pharmacosmos Holding A/S | tratamento de deficiência de ferro com carboximaltose férrica |
EP3897661A1 (en) | 2018-12-21 | 2021-10-27 | Vifor (International) Ag | Ferric carboxymaltose in the treatment of heart failure and in the treatment of congestion in heart failure |
CN110218267B (zh) * | 2019-07-04 | 2020-08-07 | 汉邦环宇多糖生物科技(河源)有限公司 | 一种右旋糖酐铁的制备方法及用途 |
US11447513B2 (en) * | 2020-02-12 | 2022-09-20 | Rk Pharma Inc. | Purification process of ferric carboxymaltose |
GB202005054D0 (en) | 2020-04-06 | 2020-05-20 | Nemysis Ltd | Carboxylate Ligand Modified Ferric Iron Hydroxide Compositions for Use in the Treatment or Prevention of Iron Deficiency Associated with Liver Diseases |
TWI784646B (zh) | 2021-07-29 | 2022-11-21 | 台耀化學股份有限公司 | 製備羧基麥芽糖鐵的方法 |
WO2023041957A1 (en) * | 2021-09-16 | 2023-03-23 | Virchow Biotech Private Limited | Efficient process for the synthesis of iron (iii) carbohydrate complexes |
WO2024069644A1 (en) * | 2022-09-30 | 2024-04-04 | West Bengal Chemical Industries Limited | A pharmaceutically acceptable ferric carboxymaltose and preparation thereof |
Family Cites Families (114)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA623411A (en) | 1961-07-04 | Muller Arthur | Process for the manufacture of iron-polyisomaltose complex for therapeutical purposes | |
DE370194C (de) | 1923-02-28 | Therese Rocksch Geb Laschet | Elektrolytisches Zinnbad zur Darstellung schwammfreier Zinnkristalle | |
US1129307A (en) * | 1914-12-26 | 1915-02-23 | Howard L Marsh | Process of forming compounds of iron and carbohydrates. |
GB199951A (en) | 1922-07-07 | 1923-07-05 | William Swann | Improvements in or relating to clamps or fastening devices for the brake chains of perambulators, and the like |
DE461370C (de) | 1925-06-13 | 1928-06-21 | Chem Fab Vormals Sandoz | Verfahren zur Herstellung von Monocarbonsaeuren aus Aldosen |
GB289280A (en) | 1927-06-17 | 1928-04-26 | Chem Fab Vormals Sandoz | Process for the oxidation of aldoses |
GB335965A (en) | 1929-06-05 | 1930-10-06 | Ig Farbenindustrie Ag | Process for the manufacture of complex iron compounds |
US2807610A (en) | 1952-02-15 | 1957-09-24 | Baker Chem Co J T | Hydrogenated dextran |
GB748024A (en) | 1953-02-27 | 1956-04-18 | Benger S Ltd | Improved therapeutic preparations of iron |
GB828404A (en) * | 1958-05-07 | 1960-02-17 | Chugai Pharmaceutical Co Ltd | A process for preparing divalent or trivalent metallic salts of glucuronic acid |
GB879441A (en) | 1959-05-25 | 1961-10-11 | Crookes Lab Ltd | Improved injectable iron preparations |
US3065138A (en) | 1959-10-09 | 1962-11-20 | Warren Teed Products Company | Therapeutic preparations of elemental iron |
GB928238A (en) | 1960-01-14 | 1963-06-12 | Diamond Lab Inc | Methods of preparing therapeutic preparations of iron |
US3100202A (en) | 1960-06-17 | 1963-08-06 | Muller Arthur | Process for preparing an iron hydroxide polyisomaltose complex and the resulting product |
US3086009A (en) * | 1960-07-19 | 1963-04-16 | Diamond Lab Inc | Process for preparing a water soluble hydrolyzed starch-ferric iron complex |
GB978485A (en) | 1960-10-26 | 1964-12-23 | Astra Apotekarnes Kem Fab | Iron preparations for intramuscular injection |
GB928236A (en) | 1960-11-22 | 1963-06-12 | Atomic Energy Authority Uk | Improvements in or relating to organic liquid moderated and cooled nuclear reactors |
US3151107A (en) | 1960-12-22 | 1964-09-29 | Central Pharmacal Company | Water-soluble iron complexes of carboxymethyl dextran |
US3076798A (en) * | 1961-02-23 | 1963-02-05 | Hausmann Lab Ltd | Process for preparing a ferric hydroxide polymaltose complex |
GB985206A (en) | 1961-12-20 | 1965-03-03 | Hausmann Ag Labor | Improvements in or relating to therapeutic iron preparation |
ES282099A1 (es) | 1962-11-02 | 1963-01-01 | Rocador Sa | Procedimiento para la preparación de un complejo de óxido de hierro y ácidos dextránicos |
BE652508A (ar) * | 1963-08-30 | |||
FR1451203A (fr) * | 1964-01-31 | 1966-01-07 | Rocador Sa | Procédé pour la fabrication d'un complexe d'oxyde ferrique et de polysaccharide |
DE1617463A1 (de) * | 1965-11-20 | 1971-04-08 | Bayer Ag | Verfahren zur Herstellung von injizierbaren kolloidalen Eisenzubereitungen |
US3639588A (en) | 1966-10-22 | 1972-02-01 | Fisons Pharmaceuticals Ltd | Pharmaceutical compositions containing ferric hydroxide complexed with dextran or dextrin heptonic acids |
GB1183940A (en) | 1966-10-22 | 1970-03-11 | Fisons Pharmaceuticals Ltd | Ferric Hydroxide Complexes |
SE322866B (ar) * | 1966-12-15 | 1970-04-20 | Astra Ab | |
GB1200902A (en) * | 1967-05-13 | 1970-08-05 | Fisons Pharmaceuticals Ltd | Iron-dextran complexes |
GB1199951A (en) | 1967-05-13 | 1970-07-22 | Fisons Pharmaceuticals Ltd | Modified Dextran and Derivatives Thereof |
US3395229A (en) | 1967-07-03 | 1968-07-30 | Mattox And Moore Inc | Process and product for combatting iron deficiency anemia in suckling pigs |
AT279048B (de) * | 1967-07-04 | 1970-02-25 | Pharmazeutische Fabrik Montavit Gmbh | Verfahren zur Herstellung neuer, löslicher und stabiler organischer Eisen(III)-Komplexverbindungen und Injektionslösungen davon |
GB1258566A (ar) | 1968-07-12 | 1971-12-30 | ||
US3908004A (en) * | 1970-05-20 | 1975-09-23 | C L Basingstoke Limited | Process for making injectable iron compositions for treating iron-deficiency anemia |
US3821192A (en) * | 1971-08-18 | 1974-06-28 | Central Pharmacal Co | Process for preparing an iron-saccharide complex |
SE359447B (ar) | 1971-10-06 | 1973-09-03 | Astra Laekemedel Ab | |
US3928581A (en) | 1972-09-13 | 1975-12-23 | Astra Laekemedel Ab | Certain polymer-iron complexes for treatment of iron deficiency |
US3969395A (en) | 1972-10-04 | 1976-07-13 | Astra Lakemedel Aktiebolag | Polymers of hydroxy carboxylic acid and a polyhydric alcohol |
US3965133A (en) | 1972-10-04 | 1976-06-22 | Astra Lakemedel Aktiebolag | Polymer |
US4056672A (en) | 1973-03-22 | 1977-11-01 | Astra Lakemedel Aktiebolag | Polymer prepared by cyanhydrin method |
JPS6039681B2 (ja) | 1976-01-01 | 1985-09-07 | 日本臓器製薬株式会社 | デキストリン・クエン酸・第二鉄多核複合体及び該複合体を含有する非経口用鉄剤 |
US4180567A (en) * | 1977-09-02 | 1979-12-25 | Pharmachem Corporation | Iron preparations and methods of making and administering the same |
US4370476A (en) | 1979-07-17 | 1983-01-25 | Usher Thomas C | Dextran polycarboxylic acids, ferric hydroxide complexes |
DE3026868C2 (de) * | 1980-07-16 | 1986-03-13 | Laboratorien Hausmann AG, St. Gallen | Verfahren zur Herstellung von Eisen(III)hydroxid-Dextran-Komplexen und sie enthaltende pharmazeutische sterile wäßrige Lösung |
US4335116A (en) | 1980-10-07 | 1982-06-15 | University Patents, Inc. | Mineral-containing therapeutic compositions |
DE51707T1 (de) | 1980-11-12 | 1983-04-14 | Izu West Hill Ontario Hattori | Dextranpolycarboxylierte saeuren, ihre komplexe mit ferrihydroxyd, sie enthaltende arzneimittel und verfahren zu deren herstellung. |
DE3114699A1 (de) | 1981-04-10 | 1982-10-28 | Siemens AG, 1000 Berlin und 8000 München | Vorrichtung zum messen der roentgenroehrenhochspannung |
HU187167B (en) | 1982-10-15 | 1985-11-28 | Richter Gedeon Vegyeszet | Process for producing pharmaceutical solution of new type polynuclear iron/iii/ mixed complex activity |
CS245379B1 (cs) | 1983-12-12 | 1986-09-18 | Karel Capek | Způsob výroby komplexů sacharózy s biogenními prvky |
US4788281A (en) | 1984-01-04 | 1988-11-29 | Tosoni Anthony L | Dextran hexonic acid derivative, ferric hydroxide complex and method manufacture thereof |
DE3443251C2 (de) * | 1984-11-23 | 1998-03-12 | Schering Ag | Eisenoxid-Komplexe für die NMR-Diagnostik, diese Verbindungen enthaltende diagnostische Mittel, ihre Verwendung und Verfahren zu deren Herstellung |
US5746999A (en) | 1984-11-23 | 1998-05-05 | Schering Aktiengesellschaft | Magnetic particles for diagnostic purposes |
US4640837A (en) | 1985-10-15 | 1987-02-03 | General Foods Corporation | Coating composition for microwave cooking |
US5102652A (en) | 1986-07-03 | 1992-04-07 | Advanced Magnetics Inc. | Low molecular weight carbohydrates as additives to stabilize metal oxide compositions |
US5160726A (en) * | 1990-02-15 | 1992-11-03 | Advanced Magnetics Inc. | Filter sterilization for production of colloidal, superparamagnetic MR contrast agents |
KR880012235A (ko) | 1987-04-10 | 1988-11-26 | 벤자민 에프.람버트 | 정상 포유동물의 헤마토크릿을 증가시키는 방법 |
GB8902894D0 (en) | 1989-02-09 | 1989-03-30 | Fisons Plc | Compositions |
JP2726520B2 (ja) | 1989-10-20 | 1998-03-11 | 名糖産業株式会社 | 有機磁性複合体 |
ES2074528T3 (es) | 1989-11-10 | 1995-09-16 | Tno | Metodo para la preparacion de polidicarboxisacaridos. |
DE10199064I2 (de) | 1991-06-11 | 2004-07-12 | Meito Sangyo Kk | Oxidierte Zusammensetzung, enthaltend ein wasserlösliches Carboxypolysaccharid und magnetisches Eisenoxid. |
TW293036B (ar) | 1992-11-27 | 1996-12-11 | Takeda Pharm Industry Co Ltd | |
EP0634174A1 (en) | 1993-07-13 | 1995-01-18 | Takeda Chemical Industries, Ltd. | Antianemic composition for veterinary use |
NL194919C (nl) | 1993-09-07 | 2003-07-04 | Tno | Werkwijze voor het oxideren van koolhydraten. |
FR2720398B1 (fr) * | 1994-05-26 | 1996-07-05 | Commissariat Energie Atomique | Complexes de métaux trivalents avec un polyol tel que le cis-inositol, utilisables à des fins médicales et leur procédé de préparation. |
GB9514090D0 (en) * | 1995-07-11 | 1995-09-13 | Cerestar Holding Bv | Non-catalysed oxidation of maltodextrin with an oxygen containing oxidant |
US5624668A (en) * | 1995-09-29 | 1997-04-29 | Luitpold Pharmaceuticals, Inc. | Iron dextran formulations |
EP0859795B1 (en) | 1995-11-09 | 2003-04-02 | Abbott Laboratories | Process for making crystalline iron dextran |
FR2742755B1 (fr) * | 1995-12-21 | 1998-02-20 | Roquette Freres | Procede perfectionne d'oxydation des sucres |
US5756715A (en) | 1996-11-08 | 1998-05-26 | Abbott Laboratories | Process for making crystalline iron dextran |
CA2195283C (en) | 1997-01-16 | 2008-07-22 | Thomas C. Usher | Process for manufacturing iron dextran using ultrafiltration |
IT1291289B1 (it) | 1997-04-30 | 1999-01-07 | Derivati Organici Lab | Complessi costituiti da fe(iii) un composto poliidrossilato e ovalbumina |
DK172860B1 (da) | 1998-03-25 | 1999-08-16 | Pharmacosmos Holding As | Jerndextranforbindelse til anvendelse som komponent i et terapeutisk middel til forebyggelse af eller behandling af jernman |
DE19833548A1 (de) | 1998-07-25 | 2000-02-03 | Messer Griesheim Gmbh | Überkritische Fluorierung |
US6587550B2 (en) | 1998-09-02 | 2003-07-01 | Michael O. Council | Method and apparatus for enabling a fee to be charged to a party initiating an electronic mail communication when the party is not on an authorization list associated with the party to whom the communication is directed |
DK173138B1 (da) | 1998-11-20 | 2000-02-07 | Pharmacosmos Holding As | Fremgangsmåde til fremstilling af en jerndextranforbindelse, jerndextranforbindelse fremstillet efter fremgangsmåden, farma |
ATE446108T1 (de) | 1999-04-09 | 2009-11-15 | Amag Pharmaceuticals Inc | Hitzebeständige umhüllte kolloidale eisenoxide |
US7871597B2 (en) | 1999-04-09 | 2011-01-18 | Amag Pharmaceuticals, Inc. | Polyol and polyether iron oxide complexes as pharmacological and/or MRI contrast agents |
US6703499B1 (en) | 1999-04-29 | 2004-03-09 | Polydex Pharmaceuticals Ltd. | Process of making carboxylated dextran |
US6521247B1 (en) | 1999-08-13 | 2003-02-18 | Warner Chilcott Laboratories Ireland Limited | Dual iron containing nutritional supplement |
US6495177B1 (en) | 1999-08-13 | 2002-12-17 | Warner Chilcott Laboratories Ireland Limited | Orally dissolvable nutritional supplement |
AT500063A1 (de) | 1999-11-23 | 2005-10-15 | Sandoz Ag | Beschichtete tablettenkerne |
US20020119174A1 (en) | 2000-07-26 | 2002-08-29 | Gardlik John Michael | Compositions useful for regulating hair growth containing metal complexes of oxidized carbohydrates |
CN1353194A (zh) * | 2000-11-02 | 2002-06-12 | 杨敏 | 生产20%右旋糖酐铁的方法 |
US6929954B2 (en) * | 2000-11-02 | 2005-08-16 | Chromaceutical Advanced Technologies, Inc. | Method for producing purified hematinic iron-saccharidic complex and product produced |
EP1719495A3 (en) | 2000-11-02 | 2007-05-02 | Chromaceutical Advanced Technologies, Inc. | Method for producing purified hematinic iron-saccharidic complex and product produced |
BR0115100A (pt) * | 2000-11-02 | 2003-09-30 | Chromaceutical Advanced Tech | Métodos para monitorar um produto de complexo ferro-sacarìdico, para purificar uma composição, e para produzir uma composição hematìnica, complexo ferro-sacarìdico, e, complexo hematìnico reconstituìdo |
DK1363951T3 (da) | 2000-12-07 | 2007-03-12 | Ad Zdravlje Farmaceutsko Hemij | Polynukleært jern(III)kompleks med pullulanoligomerer, fremgangsmåde til dens opnåelse og farmaceutiske præparater på basis af komplekset |
JP2002260951A (ja) | 2000-12-28 | 2002-09-13 | Denso Corp | 積層型誘電素子及びその製造方法,並びに電極用ペースト材料 |
EA006720B1 (ru) | 2002-04-09 | 2006-04-28 | Фармакосмос Холдинг А/С | Железосодержащие соединения декстрина для лечения железодефицитной анемии |
PL375161A1 (en) | 2002-06-21 | 2005-11-28 | University Of Pittsburgh Of The Commonwealth System Of Higher Education | Pharmaceutical use of nitric oxide, heme oxygenase-1 and products of heme degradation |
DK1540338T3 (da) | 2002-08-26 | 2009-02-09 | Vifor Int Ag | Bioækvivalenstest for jernholdige formuleringer |
US7169359B2 (en) * | 2002-08-26 | 2007-01-30 | Luitpold Pharmaceuticals, Inc. | Bioequivalence test for iron-containing formulations |
DE10249552A1 (de) * | 2002-10-23 | 2004-05-13 | Vifor (International) Ag | Wasserlösliche Eisen-Kohlenhydrat-Komplexe, deren Herstellung und diese enthaltende Arzneimittel |
US20060116349A1 (en) | 2003-03-14 | 2006-06-01 | Luitpold Pharmaceuticals, Inc. | Methods and compositions for administration of iron for the treatment of restless leg syndrome |
US6960571B2 (en) * | 2003-03-14 | 2005-11-01 | Luitpold Pharmaceuticals, Inc. | Methods and compositions for administration of iron for the treatment of restless leg syndrome |
US7964568B2 (en) * | 2003-05-30 | 2011-06-21 | Chromaceutical Advanced Technologies, Inc. | Synthesis of high molecular weight iron-saccharidic complexes |
US8614204B2 (en) | 2003-06-06 | 2013-12-24 | Fibrogen, Inc. | Enhanced erythropoiesis and iron metabolism |
AU2004285532A1 (en) | 2003-10-31 | 2005-05-12 | Alza Corporation | Administration of levodopa and carbidopa |
US20060134227A1 (en) | 2004-12-22 | 2006-06-22 | Bortz Jonathan D | Compositions including iron |
RU2359680C2 (ru) | 2005-02-09 | 2009-06-27 | Вифор (Интернациональ) Аг | Применение комплексных соединений железа (iii) |
US7815621B2 (en) * | 2005-07-07 | 2010-10-19 | Eisai R & D Management Co. Ltd. | Recovery system |
EP1757299A1 (de) | 2005-08-25 | 2007-02-28 | Vifor (International) Ag | Eisen(III)-Komplexverbindungen zur Behandlung von Eisenmangel-Zuständen bei Patienten mit chronisch-entzündlicher Darmerkrankung |
US7660481B2 (en) | 2005-11-17 | 2010-02-09 | Vital Images, Inc. | Image enhancement using anisotropic noise filtering |
EP1790356A1 (de) | 2005-11-24 | 2007-05-30 | Vifor (International) Ag | Präparat, umfassend Eisen(III)-Komplexverbindungen und redoxaktive Substanz(en) |
EP3081219A1 (en) | 2006-01-06 | 2016-10-19 | Luitpold Pharmaceuticals, Inc. | Methods and compositions for administration of iron |
US8071542B2 (en) | 2007-01-29 | 2011-12-06 | Chyna, LLC | Use of ferritin to treat iron deficiency disorders |
US8778878B2 (en) | 2007-01-29 | 2014-07-15 | Chyna, LLC | Use of ferritin to treat iron disorders |
EP1997833A1 (de) * | 2007-05-29 | 2008-12-03 | Vifor (International) Ag | Wasserlösliche Eisen-Kohlenhydratderivat-Komplexe, deren Herstellung und diese enthaltende Arzneimittel |
WO2011055374A2 (en) | 2009-11-04 | 2011-05-12 | Symed Labs Limited | Process for the preparation of iron (iii) carboxymaltose complex |
BRPI0904979A2 (pt) | 2009-12-04 | 2011-07-19 | Braskem Sa | processo para produção de olefinas, olefina, poliolefina, e, uso da poliolefina |
US9120838B2 (en) | 2011-04-18 | 2015-09-01 | Curators Of The University Of Missouri | Saccharide conjugates |
US8772101B2 (en) | 2012-11-08 | 2014-07-08 | Globalfoundries Inc. | Methods of forming replacement gate structures on semiconductor devices and the resulting device |
WO2016151367A1 (en) | 2015-03-23 | 2016-09-29 | Suven Life Sciences Limited | Preparation of water soluble trivalent iron carbohydrate complexes |
WO2016181195A1 (en) | 2015-05-08 | 2016-11-17 | Suven Life Sciences Limited | Improved process for water soluble iron carbohydrate complexes |
EP3339329A1 (en) | 2016-12-22 | 2018-06-27 | LEK Pharmaceuticals d.d. | Selective oxidation of maltodextrin and its use in the preparation of water-soluble iron (iii) carboxymaltose complexes |
-
2002
- 2002-10-23 DE DE10249552A patent/DE10249552A1/de not_active Ceased
-
2003
- 2003-10-02 JO JOP/2003/0130A patent/JO3286B1/ar active
- 2003-10-02 AR ARP030103595A patent/AR041472A1/es active IP Right Grant
- 2003-10-17 MY MYPI20033973A patent/MY134394A/en unknown
- 2003-10-20 CA CA2493806A patent/CA2493806C/en not_active Expired - Lifetime
- 2003-10-20 AT AT03769422T patent/ATE507246T1/de active
- 2003-10-20 ES ES03769422T patent/ES2364136T3/es not_active Expired - Lifetime
- 2003-10-20 PT PT03769422T patent/PT1554315E/pt unknown
- 2003-10-20 MX MXPA05004300A patent/MXPA05004300A/es active IP Right Grant
- 2003-10-20 BR BRPI0315452A patent/BRPI0315452B8/pt active IP Right Grant
- 2003-10-20 EP EP03769422A patent/EP1554315B1/de not_active Expired - Lifetime
- 2003-10-20 SI SI200331998T patent/SI1554315T1/sl unknown
- 2003-10-20 WO PCT/EP2003/011596 patent/WO2004037865A1/de active Application Filing
- 2003-10-20 SI SI200332166T patent/SI2287204T1/sl unknown
- 2003-10-20 NZ NZ539243A patent/NZ539243A/en not_active IP Right Cessation
- 2003-10-20 JP JP2004545899A patent/JP4777653B2/ja not_active Expired - Lifetime
- 2003-10-20 DK DK03769422.1T patent/DK1554315T3/da active
- 2003-10-20 EP EP10194332A patent/EP2287204B1/de not_active Expired - Lifetime
- 2003-10-20 AU AU2003278111A patent/AU2003278111C1/en active Active
- 2003-10-20 DE DE50313653T patent/DE50313653D1/de not_active Expired - Lifetime
- 2003-10-20 ES ES10194332T patent/ES2385788T3/es not_active Expired - Lifetime
- 2003-10-20 KR KR1020057005320A patent/KR100992178B1/ko active IP Right Grant
- 2003-10-20 CN CNB2003801018021A patent/CN100480275C/zh not_active Expired - Lifetime
- 2003-10-20 RU RU2005115455/04A patent/RU2303039C2/ru active Protection Beyond IP Right Term
- 2003-10-20 DK DK10194332.2T patent/DK2287204T3/da active
- 2003-10-20 BR BRPI0318840A patent/BRPI0318840B8/pt active IP Right Grant
- 2003-10-20 US US10/531,895 patent/US7612109B2/en not_active Expired - Lifetime
- 2003-10-20 PT PT10194332T patent/PT2287204E/pt unknown
- 2003-10-21 UY UY28033A patent/UY28033A1/es not_active IP Right Cessation
- 2003-10-22 TW TW092129309A patent/TWI265028B/zh active
- 2003-10-22 PE PE2003001069A patent/PE20040571A1/es active IP Right Grant
- 2003-12-16 SA SA03240447A patent/SA03240447B1/ar unknown
-
2005
- 2005-02-08 IL IL166747A patent/IL166747A/en unknown
- 2005-05-13 NO NO20052410A patent/NO333008B1/no not_active IP Right Cessation
- 2005-05-23 ZA ZA200504174A patent/ZA200504174B/en unknown
-
2006
- 2006-04-03 HK HK06104091.4A patent/HK1081976A1/xx not_active IP Right Cessation
-
2009
- 2009-10-19 US US12/581,212 patent/US20100099647A1/en not_active Abandoned
-
2010
- 2010-11-08 JP JP2010249767A patent/JP5289413B2/ja not_active Expired - Lifetime
-
2011
- 2011-04-11 HK HK11103603.0A patent/HK1149574A1/xx not_active IP Right Cessation
- 2011-05-02 NO NO20110654A patent/NO335770B1/no not_active IP Right Cessation
- 2011-05-26 JO JOP/2011/0173A patent/JOP20110173B1/ar active
- 2011-06-21 CY CY20111100589T patent/CY1112680T1/el unknown
-
2012
- 2012-06-29 CY CY20121100585T patent/CY1113387T1/el unknown
- 2012-07-24 US US13/556,733 patent/US9376505B2/en not_active Expired - Lifetime
-
2013
- 2013-03-15 US US13/835,400 patent/US10519252B2/en not_active Expired - Lifetime
-
2014
- 2014-08-27 US US14/469,864 patent/US20140371169A1/en not_active Abandoned
-
2016
- 2016-04-01 US US15/088,687 patent/US20160215071A1/en not_active Abandoned
-
2018
- 2018-05-02 JO JOP/2018/0046A patent/JOP20180046B1/ar active
-
2019
- 2019-04-19 US US16/389,272 patent/US11590097B2/en active Active
- 2019-04-19 US US16/389,234 patent/US20190276563A1/en not_active Abandoned
-
2020
- 2020-11-02 US US17/087,132 patent/US11291645B2/en not_active Expired - Lifetime
- 2020-12-23 US US17/132,652 patent/US11123321B2/en not_active Expired - Lifetime
-
2022
- 2022-08-15 US US17/888,115 patent/US20220387371A1/en active Pending
Also Published As
Similar Documents
Publication | Publication Date | Title |
---|---|---|
JOP20180046A1 (ar) | متراكبات مائية من حديد وكربوهيدرات، إنتاجها وأدوية تحتوي عليها | |
TN2009000443A1 (en) | Water-soluble iron-carbohydrate derivative complexes, the preparation thereof, and medicaments comprising them | |
YU91002A (sh) | Derivati acilfenil-karbamida, postupak za njihovu proizvodnju i njihova primena kao leka | |
DK1198411T3 (da) | Kemisk sammensætning og fremgangsmåde | |
UA74346C2 (uk) | Похідні амінодикарбонових кислот, їх застосування та лікарський засіб | |
BG105177A (en) | Novel substituted pyrazole derivatives | |
HU9600654D0 (en) | Water-soluble nimesulide salt, and uses thereof for the treatment of inflammations | |
ITMO20050056A1 (it) | Processo per la preparazione di complessi del ferro trivalente con zuccheri mono-, di- e polisaccaridi. | |
FI941119A0 (fi) | Menetelmä natriumkloridin teollisen vesilioksen valmistamiseksi ja näin saadun natriumkloridin vesiliuoksen käyttö natriumhydroksidin vesiliuoksen valmistamiseksi elektrolyyttisesti, natriumkarbonaatin valmistamiseksi ja natriumkloridikiteiden valmistamiseksi | |
GEP20053650B (en) | Disinfectant Solution Based on Sodium Hypochlorite, and Process for Preparing It | |
HUP0202749A2 (hu) | Levoszimendánt tartalmazó oldat formájú gyógyszerkészítmény | |
AR000087A1 (es) | Proceso. | |
EE04810B1 (et) | Veeparendusagens | |
HK1091146A1 (en) | New use, pharmaceutical preparations as well as a process for their production | |
EE200100627A (et) | Pressitud produktid mittepaakuvast soolast | |
HK1071144A1 (en) | Platinum complexes containing chemically modified bile acids, having antitumor activity | |
GR20000100238A (el) | Αναβραζοντα δισκια, που περιεχουν ως δραστικο συστατικο συμπλοκες ενωσεις σιδηρου, για την θεραπεια των σιδηροπενικων αναιμιων | |
TH69577A (th) | สารเชิงซ้อนของเหล็กกับคาร์โบไฮเดรตในลักษณะเป็นน้ำการผลิตและผลิตภัณฑ์ยาที่มีสารนี้เป็นส่วนประกอบ | |
Banerjee et al. | Kinetics and mechanism of redox reactions of oxo-bridged complexes of higher-valent manganese | |
TH114614B (th) | สารเชิงซ้อนอนุพันธ์เหล็ก-คาร์โบไฮเดรตที่ละลายน้ำได้ การเตรียมของมัน และเวชภัณฑ์ที่ประกอบด้วยสารเชิงซ้อนเหล่านี้ | |
MD2467F1 (en) | Process for sugar beet cultivation | |
GEP20002133B (en) | Process for Iodizing of Plant Raw | |
TH114614A (th) | สารเชิงซ้อนอนุพันธ์เหล็ก-คาร์โบไฮเดรตที่ละลายน้ำได้ การเตรียมของมันและเวชภัณฑ์ที่ประกอบด้วยสารเชิงซ้อนเหล่านี้ | |
JPS5269890A (en) | Production of stable aqueous solution of metal salt | |
UA34171A (uk) | Спосіб одержання пігментного двоокису титану з ільменітових концентратів |