JOP20110173B1 - متراكبات قابلة للذوبان في الماء من حديد وكربوهيدرات، إنتاجها وأدوية تحتوي عليها - Google Patents
متراكبات قابلة للذوبان في الماء من حديد وكربوهيدرات، إنتاجها وأدوية تحتوي عليهاInfo
- Publication number
- JOP20110173B1 JOP20110173B1 JOP/2011/0173A JOP20110173A JOP20110173B1 JO P20110173 B1 JOP20110173 B1 JO P20110173B1 JO P20110173 A JOP20110173 A JO P20110173A JO P20110173 B1 JOP20110173 B1 JO P20110173B1
- Authority
- JO
- Jordan
- Prior art keywords
- complexes
- production
- water
- soluble iron
- medicaments containing
- Prior art date
Links
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/28—Compounds containing heavy metals
- A61K31/295—Iron group metal compounds
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
- C08B30/00—Preparation of starch, degraded or non-chemically modified starch, amylose, or amylopectin
- C08B30/12—Degraded, destructured or non-chemically modified starch, e.g. mechanically, enzymatically or by irradiation; Bleaching of starch
- C08B30/18—Dextrin, e.g. yellow canari, white dextrin, amylodextrin or maltodextrin; Methods of depolymerisation, e.g. by irradiation or mechanically
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
- C08B31/00—Preparation of derivatives of starch
- C08B31/18—Oxidised starch
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
- A61K31/716—Glucans
- A61K31/718—Starch or degraded starch, e.g. amylose, amylopectin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
- A61K33/24—Heavy metals; Compounds thereof
- A61K33/26—Iron; Compounds thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/56—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule
- A61K47/61—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule the organic macromolecular compound being a polysaccharide or a derivative thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/06—Antianaemics
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H23/00—Compounds containing boron, silicon, or a metal, e.g. chelates, vitamin B12
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
- C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
- C08B37/0006—Homoglycans, i.e. polysaccharides having a main chain consisting of one single sugar, e.g. colominic acid
- C08B37/0009—Homoglycans, i.e. polysaccharides having a main chain consisting of one single sugar, e.g. colominic acid alpha-D-Glucans, e.g. polydextrose, alternan, glycogen; (alpha-1,4)(alpha-1,6)-D-Glucans; (alpha-1,3)(alpha-1,4)-D-Glucans, e.g. isolichenan or nigeran; (alpha-1,4)-D-Glucans; (alpha-1,3)-D-Glucans, e.g. pseudonigeran; Derivatives thereof
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
- C08B31/00—Preparation of derivatives of starch
- C08B31/18—Oxidised starch
- C08B31/185—Derivatives of oxidised starch, e.g. crosslinked oxidised starch
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Epidemiology (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biochemistry (AREA)
- Materials Engineering (AREA)
- Polymers & Plastics (AREA)
- Molecular Biology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Crystallography & Structural Chemistry (AREA)
- Inorganic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Hematology (AREA)
- Diabetes (AREA)
- Biotechnology (AREA)
- Genetics & Genomics (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Polysaccharides And Polysaccharide Derivatives (AREA)
- Medicinal Preparation (AREA)
Abstract
يتعلق الاختراع الراهن بمتراكب قابل للذوبان في الماء من حديد وكربوهيدرات يمكن الحصول عليه من محلول مائي لملح الحديد (III) ومحلول مائي للمنتج الناتج عن أكسدة مركب مالتودكسترين واحد أو أكثر له مكافئ دكستروز يتراوح من 5 إلى 22 باستخدام محلول هيبوكلوريت مائي عند درجة حموضة تتراوح من 8.5 إلى 12، ويتعلق الاختراع الراهن بعملية لإنتاجه وبدواء لمعالجة حالات مرضية ناشئة عن نقص الحديد.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE10249552A DE10249552A1 (de) | 2002-10-23 | 2002-10-23 | Wasserlösliche Eisen-Kohlenhydrat-Komplexe, deren Herstellung und diese enthaltende Arzneimittel |
Publications (1)
Publication Number | Publication Date |
---|---|
JOP20110173B1 true JOP20110173B1 (ar) | 2021-08-17 |
Family
ID=32102937
Family Applications (3)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JOP/2003/0130A JO3286B1 (ar) | 2002-10-23 | 2003-10-02 | متراكبات مائية من حديد و كربوهيدرات,انتاجها و ادوية تحتوي عليها |
JOP/2011/0173A JOP20110173B1 (ar) | 2002-10-23 | 2011-05-26 | متراكبات قابلة للذوبان في الماء من حديد وكربوهيدرات، إنتاجها وأدوية تحتوي عليها |
JOP/2018/0046A JOP20180046B1 (ar) | 2002-10-23 | 2018-05-02 | متراكبات قابلة للذوبان في الماء من حديد وكربوهيدرات، إنتاجها وأدوية تحتوي عليها |
Family Applications Before (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JOP/2003/0130A JO3286B1 (ar) | 2002-10-23 | 2003-10-02 | متراكبات مائية من حديد و كربوهيدرات,انتاجها و ادوية تحتوي عليها |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JOP/2018/0046A JOP20180046B1 (ar) | 2002-10-23 | 2018-05-02 | متراكبات قابلة للذوبان في الماء من حديد وكربوهيدرات، إنتاجها وأدوية تحتوي عليها |
Country Status (30)
Country | Link |
---|---|
US (11) | US7612109B2 (ar) |
EP (2) | EP2287204B1 (ar) |
JP (2) | JP4777653B2 (ar) |
KR (1) | KR100992178B1 (ar) |
CN (1) | CN100480275C (ar) |
AR (1) | AR041472A1 (ar) |
AT (1) | ATE507246T1 (ar) |
AU (1) | AU2003278111C1 (ar) |
BR (2) | BRPI0318840B8 (ar) |
CA (1) | CA2493806C (ar) |
CY (2) | CY1112680T1 (ar) |
DE (2) | DE10249552A1 (ar) |
DK (2) | DK1554315T3 (ar) |
ES (2) | ES2385788T3 (ar) |
HK (2) | HK1081976A1 (ar) |
IL (1) | IL166747A (ar) |
JO (3) | JO3286B1 (ar) |
MX (1) | MXPA05004300A (ar) |
MY (1) | MY134394A (ar) |
NO (2) | NO333008B1 (ar) |
NZ (1) | NZ539243A (ar) |
PE (1) | PE20040571A1 (ar) |
PT (2) | PT2287204E (ar) |
RU (1) | RU2303039C2 (ar) |
SA (1) | SA03240447B1 (ar) |
SI (2) | SI2287204T1 (ar) |
TW (1) | TWI265028B (ar) |
UY (1) | UY28033A1 (ar) |
WO (1) | WO2004037865A1 (ar) |
ZA (1) | ZA200504174B (ar) |
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US6757848B2 (en) | 2001-06-19 | 2004-06-29 | Hewlett-Packard Development Company, L.P. | Recovery of user data from partially incorrect data set in tape data storage system |
DE10249552A1 (de) | 2002-10-23 | 2004-05-13 | Vifor (International) Ag | Wasserlösliche Eisen-Kohlenhydrat-Komplexe, deren Herstellung und diese enthaltende Arzneimittel |
DE102004031181A1 (de) * | 2004-06-28 | 2006-01-19 | Vifor (International) Ag | Phosphatadsorbens |
ES2333814T3 (es) | 2005-02-09 | 2010-03-01 | Vifor (International) Ag | Uso de compuestos de complejo de hierro (iii). |
ITMO20050056A1 (it) | 2005-03-15 | 2006-09-16 | Biofer Spa | Processo per la preparazione di complessi del ferro trivalente con zuccheri mono-, di- e polisaccaridi. |
EP1757299A1 (de) * | 2005-08-25 | 2007-02-28 | Vifor (International) Ag | Eisen(III)-Komplexverbindungen zur Behandlung von Eisenmangel-Zuständen bei Patienten mit chronisch-entzündlicher Darmerkrankung |
EP1790356A1 (de) * | 2005-11-24 | 2007-05-30 | Vifor (International) Ag | Präparat, umfassend Eisen(III)-Komplexverbindungen und redoxaktive Substanz(en) |
EP2626074A1 (en) * | 2006-01-06 | 2013-08-14 | Luitpold Pharmaceuticals, Inc. | Methods and compositions for administration of iron |
AU2016205002C1 (en) * | 2006-01-06 | 2020-09-24 | Vifor (International) Ag | Methods and compositions for administration of iron |
AU2013206429B2 (en) * | 2006-01-06 | 2016-04-28 | Vifor (International) Ag | Methods and compositions for administration of iron |
EP1941869A1 (en) * | 2007-01-04 | 2008-07-09 | Vifor (International) Ag | Multicompartment bag for storage of iron preparations |
EP1947120A1 (de) * | 2007-01-19 | 2008-07-23 | Vifor (International) Ag | Eisen-Kohlenhydrat-Komplex-Verbindungen |
CA2676146C (en) * | 2007-02-06 | 2016-08-09 | Medical Research Council | Ligand modified poly oxo-hydroxy metal ion materials, their uses and processes for their preparation |
EP1997833A1 (de) * | 2007-05-29 | 2008-12-03 | Vifor (International) Ag | Wasserlösliche Eisen-Kohlenhydratderivat-Komplexe, deren Herstellung und diese enthaltende Arzneimittel |
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US9384629B2 (en) | 2014-03-31 | 2016-07-05 | Fresh Idea Global Limited | Automated money laundering detection, notification, and reporting techniques implemented at casino gaming networks |
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EP2997968A1 (en) | 2014-09-22 | 2016-03-23 | Ioulia Tseti | Iron (III) hydroxide complexes with activated glucose syrups and process for preparing same |
CN104402984B (zh) * | 2014-11-11 | 2018-09-07 | 武汉科福新药有限责任公司 | 一种高载铁量的蛋白琥珀酸铁的制备方法 |
US20180105609A1 (en) * | 2015-03-23 | 2018-04-19 | Suven Life Sciences Limited | Preparation of water soluble trivalent iron carbohydrate complexes |
WO2016181195A1 (en) * | 2015-05-08 | 2016-11-17 | Suven Life Sciences Limited | Improved process for water soluble iron carbohydrate complexes |
US20180147234A1 (en) * | 2015-05-29 | 2018-05-31 | Luitpold Pharmaceuticals, Inc. | Compositions and methods for treatment of fibromyalgia |
CN105125577B (zh) * | 2015-07-29 | 2018-05-18 | 南京生命能科技开发有限公司 | 一种稳定的糖-铁复合物及其制备方法 |
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GB201517893D0 (en) | 2015-10-09 | 2015-11-25 | Medical Res Council | Methods for producing carboxylate ligand modified ferric iron hydroxide colloids |
CN105520955B (zh) * | 2015-12-21 | 2018-05-11 | 南京生命能科技开发有限公司 | 一种羧基麦芽糖铁药用组合物及其制备方法 |
CN108129582A (zh) * | 2016-12-01 | 2018-06-08 | 江苏奥赛康药业股份有限公司 | 一种铁碳水化合物复合物的制备方法 |
EP3339329A1 (en) | 2016-12-22 | 2018-06-27 | LEK Pharmaceuticals d.d. | Selective oxidation of maltodextrin and its use in the preparation of water-soluble iron (iii) carboxymaltose complexes |
MA50229A (fr) | 2017-09-11 | 2020-07-22 | Pharmacosmos Holding As | Composés complexes de fer à usage thérapeutique |
WO2019193608A1 (en) * | 2018-04-05 | 2019-10-10 | Msn Laboratories Private Limited, R&D Center | Improved process for the preparation of iron (iii) carboxymaltose |
CN108498539A (zh) * | 2018-05-03 | 2018-09-07 | 东营天东制药有限公司 | 一种水溶性铁剂复合体原料药的制备方法 |
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CN110218267B (zh) * | 2019-07-04 | 2020-08-07 | 汉邦环宇多糖生物科技(河源)有限公司 | 一种右旋糖酐铁的制备方法及用途 |
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