YU91002A - Derivati acilfenil-karbamida, postupak za njihovu proizvodnju i njihova primena kao leka - Google Patents

Derivati acilfenil-karbamida, postupak za njihovu proizvodnju i njihova primena kao leka

Info

Publication number
YU91002A
YU91002A YU91002A YUP91002A YU91002A YU 91002 A YU91002 A YU 91002A YU 91002 A YU91002 A YU 91002A YU P91002 A YUP91002 A YU P91002A YU 91002 A YU91002 A YU 91002A
Authority
YU
Yugoslavia
Prior art keywords
acylphenyl
urea derivatives
medicament
production
methods
Prior art date
Application number
YU91002A
Other languages
English (en)
Inventor
Elisabeth Defossa
Thomas Klabunde
Hans-Joerg Burger
Andreas Herling
Karl-Heinz Baringhaus
Original Assignee
Aventis Pharma Deutschland
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DE2001116768 external-priority patent/DE10116768A1/de
Application filed by Aventis Pharma Deutschland filed Critical Aventis Pharma Deutschland
Publication of YU91002A publication Critical patent/YU91002A/sh

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C275/00—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
    • C07C275/28—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton
    • C07C275/32—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton being further substituted by singly-bound oxygen atoms
    • C07C275/34—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton being further substituted by singly-bound oxygen atoms having nitrogen atoms of urea groups and singly-bound oxygen atoms bound to carbon atoms of the same non-condensed six-membered aromatic ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/08—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
    • C07D295/084—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
    • C07D295/088—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/17—Amides, e.g. hydroxamic acids having the group >N—C(O)—N< or >N—C(S)—N<, e.g. urea, thiourea, carmustine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10—Antimycotics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C275/00—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
    • C07C275/46—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups containing any of the groups, X being a hetero atom, Y being any atom, e.g. acylureas
    • C07C275/48—Y being a hydrogen or a carbon atom
    • C07C275/54—Y being a carbon atom of a six-membered aromatic ring, e.g. benzoylureas
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/34—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D307/38—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms

Abstract

Pronalazak se odnosi na derivate acilfenil-karbamida kao i na njihove fiziološki prihvatljive soli kao i na fiziološki funkcionalne derivate. Pronalazak se odnosi na jedinjenja formule (I), pri čemu ostaci imaju navedena značenja, kao i na njihove fiziološki prihvatljive soli i na postupak za njihovu proizvodnju. Jedinjenja su pogodna da se koriste na primer za lečenje Tipa II dijabetesa.[The invention relates to acylphenyl urea derivatives and the physiologically compatible salts and physiologically functional derivatives thereof. Such compounds correspond to the formula (I) wherein the radicals have the cited meanings. The invention also relates to a method for producing said compounds. Said compounds can be used, for example, for treating Type II diabetes.
YU91002A 2000-06-09 2001-05-26 Derivati acilfenil-karbamida, postupak za njihovu proizvodnju i njihova primena kao leka YU91002A (sh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE10028175 2000-06-09
DE2001116768 DE10116768A1 (de) 2001-04-04 2001-04-04 Acylphenylharnstoffderivate, Verfahren zu ihrer Herstellung und ihre Verwendung als Arzneimittel

Publications (1)

Publication Number Publication Date
YU91002A true YU91002A (sh) 2006-05-25

Family

ID=26005991

Family Applications (1)

Application Number Title Priority Date Filing Date
YU91002A YU91002A (sh) 2000-06-09 2001-05-26 Derivati acilfenil-karbamida, postupak za njihovu proizvodnju i njihova primena kao leka

Country Status (28)

Country Link
US (1) US6506778B2 (sh)
EP (1) EP1294682B1 (sh)
JP (1) JP4510372B2 (sh)
KR (1) KR20030007934A (sh)
CN (1) CN1280266C (sh)
AR (1) AR030230A1 (sh)
AT (1) ATE265424T1 (sh)
AU (2) AU6231801A (sh)
BR (1) BR0111457A (sh)
CA (1) CA2411082A1 (sh)
CZ (1) CZ20024003A3 (sh)
DE (1) DE50102147D1 (sh)
DK (1) DK1294682T3 (sh)
EE (1) EE200200634A (sh)
ES (1) ES2215902T3 (sh)
HK (1) HK1056715A1 (sh)
HR (1) HRP20020968A2 (sh)
HU (1) HUP0301749A2 (sh)
IL (1) IL153273A0 (sh)
MX (1) MXPA02011458A (sh)
NO (1) NO20025879L (sh)
NZ (1) NZ523034A (sh)
PL (1) PL359178A1 (sh)
PT (1) PT1294682E (sh)
SK (1) SK17252002A3 (sh)
TR (1) TR200401029T4 (sh)
WO (1) WO2001094300A1 (sh)
YU (1) YU91002A (sh)

Families Citing this family (47)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE10125567B4 (de) * 2001-05-25 2004-08-26 Aventis Pharma Deutschland Gmbh Carbonamid substituierte Phenylharnstoffderivate, Verfahren zu ihrer Herstellung und ihre Verwendung als Arzneimittel
PE20021091A1 (es) * 2001-05-25 2003-02-04 Aventis Pharma Gmbh Derivados de fenilurea sustituidos con carbonamida y procedimiento para su preparacion
DE10139416A1 (de) * 2001-08-17 2003-03-06 Aventis Pharma Gmbh Aminoalkyl substituierte aromatische Bicyclen, Verfahren zu ihrer Herstellung und ihre Verwendung als Arzneimittel
GB0205166D0 (en) 2002-03-06 2002-04-17 Astrazeneca Ab Chemical compounds
GB0205175D0 (en) 2002-03-06 2002-04-17 Astrazeneca Ab Chemical compounds
GB0205165D0 (en) 2002-03-06 2002-04-17 Astrazeneca Ab Chemical compounds
GB0205162D0 (en) 2002-03-06 2002-04-17 Astrazeneca Ab Chemical compounds
GB0205176D0 (en) 2002-03-06 2002-04-17 Astrazeneca Ab Chemical compounds
GB0205170D0 (en) 2002-03-06 2002-04-17 Astrazeneca Ab Chemical compounds
DE10215907A1 (de) * 2002-04-11 2003-11-06 Aventis Pharma Gmbh Acyl-4-carboxyphenyl-harnstoffderivate, Verfahren zu deren Herstellung und deren Verwendung
US7078404B2 (en) 2002-04-11 2006-07-18 Sanofi-Aventis Deutschland Gmbh Acyl-3-carboxyphenylurea derivatives, processes for preparing them and their use
US7223796B2 (en) 2002-04-11 2007-05-29 Sanofi-Aventis Deutschland Gmbh Acyl-4-carboxyphenylurea derivatives, processes for preparing them and their use
DE10215908B4 (de) * 2002-04-11 2005-08-18 Aventis Pharma Deutschland Gmbh Acyl-3-carboxyphenyl-harnstoffderivate und deren Verwendung als Arzneimittel
US7049341B2 (en) 2002-06-07 2006-05-23 Aventis Pharma Deutschland Gmbh N-benzoylureidocinnamic acid derivatives, processes for preparing them and their use
DE10225635C1 (de) * 2002-06-07 2003-12-24 Aventis Pharma Gmbh N-Benzoylureido-Zimtsäurederivate, Verfahren zu deren Herstellung und deren Verwendung
MXPA05000055A (es) * 2002-07-11 2005-04-08 Aventis Pharma Gmbh Acilureas sustituidas con urea y uretano, metodos para su produccion y su uso.
US7262220B2 (en) 2002-07-11 2007-08-28 Sanofi-Aventis Deutschland Gmbh Urea- and urethane-substituted acylureas, process for their preparation and their use
BR0312697A (pt) * 2002-07-12 2005-04-26 Aventis Pharma Gmbh Benzoiluréias substituìdas heterociclicamente, processo para a sua preparação e sua aplicação como medicamento
DE10231627B4 (de) * 2002-07-12 2006-03-09 Sanofi-Aventis Deutschland Gmbh Heterozyklisch substituierte Benzoylharnstoffe und ihre Verwendung als Arzneimittel
DE10246434B4 (de) * 2002-10-04 2005-08-04 Aventis Pharma Deutschland Gmbh Carboxyalkoxy-substituierte Acyl-carboxyphenyl-harnstoffderivate und ihre Verwendung als Arzneimittel
US20040157922A1 (en) 2002-10-04 2004-08-12 Aventis Pharma Deutschland Gmbh Carboxyalkoxy-substituted acyl-carboxyphenylurea derivatives and their use as medicaments
US7179941B2 (en) * 2003-01-23 2007-02-20 Sanofi-Aventis Deutschland Gmbh Carbonylamino-substituted acyl phenyl urea derivatives, process for their preparation and their use
DE10302452B4 (de) * 2003-01-23 2005-02-24 Aventis Pharma Deutschland Gmbh Carbonylamino-substituierte Acyl-phenyl-harnstoffderivate, Verfahren zu deren Herstellung und deren Verwendung
DE10306502B4 (de) * 2003-02-17 2005-03-17 Aventis Pharma Deutschland Gmbh Substituierte 3-(Benzoylureido)-thiophenderivate und sie enthaltende Arzneimittel
US7196114B2 (en) * 2003-02-17 2007-03-27 Sanofi-Aventis Deutschland Gmbh Substituted 3-(benzoylureido) thiophene derivatives, processes for preparing them and their use
DE10308352A1 (de) 2003-02-27 2004-09-09 Aventis Pharma Deutschland Gmbh Arylcycloalkylderivate mit verzweigten Seitenketten, Verfahren zu ihrer Herstellung und ihre Anwendung als Arzneimittel
US7148246B2 (en) 2003-02-27 2006-12-12 Sanofi-Aventis Deutschland Gmbh Cycloalkyl derivatives having bioisosteric carboxylic acid groups, processes for their preparation and their use as pharmaceuticals
DE10308351A1 (de) * 2003-02-27 2004-11-25 Aventis Pharma Deutschland Gmbh 1,3-substituierte Cycloalkylderivate mit sauren, meist heterocyclischen Gruppen, Verfahren zu ihrer Herstellung und ihre Verwendung als Arzneimittel
DE10308353A1 (de) 2003-02-27 2004-12-02 Aventis Pharma Deutschland Gmbh Diarylcycloalkylderivate, Verfahren zu ihrer Herstellung und ihre Verwendung als Arzneimittel
DE10308355A1 (de) * 2003-02-27 2004-12-23 Aventis Pharma Deutschland Gmbh Aryl-cycloalkyl substituierte Alkansäurederivate, Verfahren zu ihrer Herstellung und ihre Anwendung als Arzneimittel
DE10309929B4 (de) * 2003-03-07 2006-02-23 Sanofi-Aventis Deutschland Gmbh Substituierte Benzoylureidopyridyl-piperidin- und -pyrrolidin-carbonsäurederivate, Verfahren zu deren Herstellung und deren Verwendung
US7501440B2 (en) 2003-03-07 2009-03-10 Sanofi-Aventis Deutschland Gmbh Substituted benzoylureidopyridylpiperidine-and-pyrrolidinecarboxylic acid derivatives, processes for preparing them and their use
DE10335092B3 (de) 2003-08-01 2005-02-03 Aventis Pharma Deutschland Gmbh Substituierte Benzoylureido-o-benzoylamide, Verfahren zu deren Herstellung und deren Verwendung
US7241787B2 (en) 2004-01-25 2007-07-10 Sanofi-Aventis Deutschland Gmbh Substituted N-cycloexylimidazolinones, process for their preparation and their use as medicaments
EP1586573B1 (en) 2004-04-01 2007-02-07 Sanofi-Aventis Deutschland GmbH Oxadiazolones, processes for their preparation and their use as pharmaceuticals
US7963448B2 (en) * 2004-12-22 2011-06-21 Cognex Technology And Investment Corporation Hand held machine vision method and apparatus
EP1907367A4 (en) * 2005-04-18 2011-05-11 Saeed R Khan DEVELOPMENT AND SYNTHESIS OF NEW TUBULIN POLYMERIZATION INHIBITORS: BENZOYLPHENYL HARVEST (BPU) SULFUR ANALOGUE
KR20080012304A (ko) * 2005-05-23 2008-02-11 니뽄 다바코 산교 가부시키가이샤 피라졸 화합물 및 이들 피라졸 화합물을 포함하여이루어지는 당뇨병 치료약
DE102005026762A1 (de) 2005-06-09 2006-12-21 Sanofi-Aventis Deutschland Gmbh Azolopyridin-2-on-derivate als Inhibitoren von Lipasen und Phospholipasen
PE20110235A1 (es) 2006-05-04 2011-04-14 Boehringer Ingelheim Int Combinaciones farmaceuticas que comprenden linagliptina y metmorfina
EP2096111A1 (en) * 2006-11-20 2009-09-02 Japan Tobacco Inc. Pyrazoles and use thereof as drugs
US8969514B2 (en) 2007-06-04 2015-03-03 Synergy Pharmaceuticals, Inc. Agonists of guanylate cyclase useful for the treatment of hypercholesterolemia, atherosclerosis, coronary heart disease, gallstone, obesity and other cardiovascular diseases
US9616097B2 (en) 2010-09-15 2017-04-11 Synergy Pharmaceuticals, Inc. Formulations of guanylate cyclase C agonists and methods of use
CA2913737A1 (en) 2013-06-05 2014-12-11 Synergy Pharmaceuticals, Inc. Ultra-pure agonists of guanylate cyclase c, method of making and using same
KR102431436B1 (ko) 2014-08-29 2022-08-10 테스 파마 에스.알.엘. α-아미노-β-카복시뮤콘산 세미알데히드 데카복실라제의 억제제
WO2018069532A1 (en) 2016-10-14 2018-04-19 Tes Pharma S.R.L. Inhibitors of alpha-amino-beta-carboxymuconic acid semialdehyde decarboxylase
AU2019385644A1 (en) 2018-11-20 2021-06-03 Tes Pharma S.R.L. Inhibitors of α-Amino-β-carboxymuconic acid semialdehyde decarboxylase

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH516578A (de) * 1967-11-02 1971-12-15 Bayer Ag Verfahren zur Herstellung von heterocyclische Acylaminogruppen enthaltenden Arylsulfonylharnstoffen mit blutdrucksenkender Wirkung
ZA793186B (en) * 1978-07-06 1981-02-25 Duphar Int Res New urea and thiourea compounds, method of preparing the new compounds, as well as insecticidal compositions on the basis of these compounds
ATE43788T1 (de) * 1983-09-01 1989-06-15 Duphar Int Res Benzoylharnstoffe mit antitumoraler wirkung.
JPS60237056A (ja) * 1984-05-08 1985-11-25 Ishihara Sangyo Kaisha Ltd Ｎ−ベンゾイル−ｎ′−フエニルウレア系化合物及びそれらを含有する殺虫剤
ATE40111T1 (de) * 1984-07-05 1989-02-15 Duphar Int Res Benzoylharnstoffverbindungen sowie solche enthaltende insektizide und akarizide zusammensetzungen.
DE3504749A1 (de) * 1985-02-08 1986-08-14 Schering AG, 1000 Berlin und 4709 Bergkamen Acylharnstoffe, insektizide mittel enthaltend diese verbindungen sowie verfahren zu ihrer herstellung
JPH0791248B2 (ja) * 1988-06-29 1995-10-04 富士写真フイルム株式会社 アルコキシもしくはアリールオキシベンゼン化合物の製造方法
DE4208778C1 (sh) * 1992-03-17 1993-09-23 Schering Ag Berlin Und Bergkamen, 13353 Berlin, De
GB9313268D0 (en) * 1993-06-28 1993-08-11 Zeneca Ltd Chemical compounds

Also Published As

Publication number Publication date
EP1294682A1 (de) 2003-03-26
MXPA02011458A (es) 2003-04-25
PT1294682E (pt) 2004-09-30
JP4510372B2 (ja) 2010-07-21
PL359178A1 (en) 2004-08-23
JP2003535843A (ja) 2003-12-02
EE200200634A (et) 2004-04-15
CN1434796A (zh) 2003-08-06
HUP0301749A2 (hu) 2003-09-29
TR200401029T4 (tr) 2004-06-21
DK1294682T3 (da) 2004-08-02
KR20030007934A (ko) 2003-01-23
SK17252002A3 (sk) 2003-05-02
IL153273A0 (en) 2003-07-06
NZ523034A (en) 2004-07-30
DE50102147D1 (de) 2004-06-03
CN1280266C (zh) 2006-10-18
HK1056715A1 (en) 2004-02-27
AU6231801A (en) 2001-12-17
CA2411082A1 (en) 2002-12-05
AU2001262318B2 (en) 2005-09-08
EP1294682B1 (de) 2004-04-28
AR030230A1 (es) 2003-08-13
NO20025879D0 (no) 2002-12-06
ATE265424T1 (de) 2004-05-15
BR0111457A (pt) 2003-06-24
US20020151586A1 (en) 2002-10-17
US6506778B2 (en) 2003-01-14
WO2001094300A1 (de) 2001-12-13
NO20025879L (no) 2003-01-29
HRP20020968A2 (en) 2005-02-28
ES2215902T3 (es) 2004-10-16
CZ20024003A3 (cs) 2003-03-12

Similar Documents

Publication Publication Date Title
YU91002A (sh) Derivati acilfenil-karbamida, postupak za njihovu proizvodnju i njihova primena kao leka
BG108318A (en) Carboxamide-substituted phenylurea derivatives and method for the production and use thereof as medicaments
RS20050019A (en) Heterocyclically substituted benzoylureas,method for their production and their use as medicaments
AP1614A (en) New heterocyclic compounds, their preparation and their use as medicaments, in particular as anti-bacterial agents.
MY134892A (en) Substituted 2-thio-3,5-dicyano-4-phenyl-6-aminopyridines and their use
MXPA03006093A (es) Derivados de n(fenilsulfonil)glicina y su uso terapeutico.
UA74346C2 (uk) Похідні амінодикарбонових кислот, їх застосування та лікарський засіб
MXPA03010201A (es) Derivados de 2-piridin-ciclohexan-1,4-diamina sustituidos.
RS20050719A (en) Novel diphenyl azetidinone with improved phzsiolo gical characteristics, corresponding production method, medicaments containing said compound and use of the latter
HK1055117A1 (en) 8,8A-dihydro-indenoÄ11,2-dÜthiazole derivatives, amethod for their production and their use as medi caments.
IL176914A0 (en) Heterocyclically substituted 7-amino-4-quinolone-3-carboxylic acid derivatives, method for the production thereof and their use as medicaments
PL371127A1 (en) 6-aminomorphinane derivatives, method for the production and use thereof
IL176915A0 (en) Cycloalkyl substituted 7-amino-4-quinolone-3-carboxylic acid derivatives, method for the production thereof and their use as medicaments
IL165558A0 (en) N-benzoylureidocinnamate derivatives method for production and use thereof
HRP20050779A2 (en) Supstituted benzoylureidopyridyl-piperidine and pyrrolidine carboxylic acid derivatives, method for the production thereof and the use thereof
WO2004087700A8 (fr) Derives du benzenesulfonamide, leur procede de preparation et leur utilisation de la douleur
RS88704A (en) Acyl-3-carboxyphenylurea derivatives, method for production and use thereof
AU3321002A (en) Use of 1-phenyl-3-dimethylaminopropane compounds for treating urinary incontinence
TNSN06233A1 (en) 7-phenylamino-4-quinolone-3-carboxylic acid derivatives, methods for production and use thereof as medicaments
MA27649A1 (fr) Derives d&#39;acylphenyluree substitues par carbonylamino, methode de production et d&#39;utilisation de ceux-ci.
MXPA05008331A (es) Derivados de 3-(benzoilureido)-tiofeno sustituido, metodo para su produccion y uso de los mismos.
MY127328A (en) 5-amino-1-pentene-3-ol substituted derivatives
WO2004033416A3 (de) Carboxyalkoxy-substituierte acyl-carboxyphenyl-harnstoffderivate, verfahren zu ihre herstellung und ihre verwendung als arzneimittel
MXPA04001856A (es) Indan-1-oles c2-sustituidos y sus derivados, metodo para su produccion y su uso como medicamentos.
MXPA04001852A (es) Uso de sistemas indan-1-ol c2-sustituidas para la produccion de medicamentos para la profilaxis o tratamiento de obesidad.