HRP20050779A2 - Supstituted benzoylureidopyridyl-piperidine and pyrrolidine carboxylic acid derivatives, method for the production thereof and the use thereof - Google Patents

Supstituted benzoylureidopyridyl-piperidine and pyrrolidine carboxylic acid derivatives, method for the production thereof and the use thereof

Info

Publication number
HRP20050779A2
HRP20050779A2 HR20050779A HRP20050779A HRP20050779A2 HR P20050779 A2 HRP20050779 A2 HR P20050779A2 HR 20050779 A HR20050779 A HR 20050779A HR P20050779 A HRP20050779 A HR P20050779A HR P20050779 A2 HRP20050779 A2 HR P20050779A2
Authority
HR
Croatia
Prior art keywords
benzoylureidopyridyl
piperidine
production
carboxylic acid
acid derivatives
Prior art date
Application number
HR20050779A
Other languages
Croatian (hr)
Inventor
Schoenafinger Karl
Kadereit Dieter
Defossa Elisabeth
Herling Andreas
Klabunde Thomas
Original Assignee
Sanofi-Aventis Deutschland Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sanofi-Aventis Deutschland Gmbh filed Critical Sanofi-Aventis Deutschland Gmbh
Publication of HRP20050779A2 publication Critical patent/HRP20050779A2/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/48—Drugs for disorders of the endocrine system of the pancreatic hormones
    • A61P5/50—Drugs for disorders of the endocrine system of the pancreatic hormones for increasing or potentiating the activity of insulin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Diabetes (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Endocrinology (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Emergency Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

The invention relates to substituted benzoylureidopyridyl-piperidine and -pyrrolidine carboxylic acid derivatives, to a method for the production thereof, and to their use. The invention concerns both compounds of formula (I), wherein the radicals have the cited meanings, as well as physiologically compatible salts of said compounds. These compounds are suited for use as, e.g. medicaments for preventing and treating Type 2 diabetes.
HR20050779A 2003-03-07 2005-09-06 Supstituted benzoylureidopyridyl-piperidine and pyrrolidine carboxylic acid derivatives, method for the production thereof and the use thereof HRP20050779A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE10309929A DE10309929B4 (en) 2003-03-07 2003-03-07 Substituted benzoylureidopyridyl-piperidine and -pyrrolidine-carboxylic acid derivatives, process for their preparation and their use
PCT/EP2004/001735 WO2004078743A1 (en) 2003-03-07 2004-02-21 Substituted benzoylureidopyridyl-piperidine and -pyrrolidine carboxylic acid derivatives, method for the production thereof and the use thereof

Publications (1)

Publication Number Publication Date
HRP20050779A2 true HRP20050779A2 (en) 2006-10-31

Family

ID=32945839

Family Applications (1)

Application Number Title Priority Date Filing Date
HR20050779A HRP20050779A2 (en) 2003-03-07 2005-09-06 Supstituted benzoylureidopyridyl-piperidine and pyrrolidine carboxylic acid derivatives, method for the production thereof and the use thereof

Country Status (18)

Country Link
EP (1) EP1603895B1 (en)
JP (1) JP2006519795A (en)
KR (1) KR20050108487A (en)
CN (1) CN1759109A (en)
AT (1) ATE386735T1 (en)
AU (1) AU2004218267A1 (en)
BR (1) BRPI0408148A (en)
CA (1) CA2518322A1 (en)
CO (1) CO5690587A2 (en)
DE (2) DE10309929B4 (en)
HR (1) HRP20050779A2 (en)
MA (1) MA27745A1 (en)
MX (1) MXPA05009122A (en)
NO (1) NO20054418L (en)
PL (1) PL377293A1 (en)
RU (1) RU2005131011A (en)
WO (1) WO2004078743A1 (en)
ZA (1) ZA200506119B (en)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2006055435A1 (en) 2004-11-15 2006-05-26 Bristol-Myers Squibb Company 2-aminonaphthalene derivatives and related glycogen phosphorylase inhibitors
US7214704B2 (en) 2004-11-15 2007-05-08 Bristol-Myers Squibb Company 2-Amino-1-functionalized tetralin derivatives and related glycogen phosphorylase inhibitors
US7365061B2 (en) 2004-11-15 2008-04-29 Bristol-Myers Squibb Company 2-Amino-3-functionalized tetralin derivatives and related glycogen phosphorylase inhibitors
WO2006055462A1 (en) 2004-11-15 2006-05-26 Bristol-Myers Squibb Company 2-amino-4-functionalized tetralin derivatives and related glycogen phosphorylase inhibitors
PE20080251A1 (en) 2006-05-04 2008-04-25 Boehringer Ingelheim Int USES OF DPP IV INHIBITORS
KR20120104534A (en) * 2009-10-06 2012-09-21 브리스톨-마이어스 스큅 컴퍼니 Pyrrolidine gpr40 modulators

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3034004A1 (en) * 1980-09-10 1982-04-22 Hoechst Ag, 6000 Frankfurt SULFONYL UREAS, METHOD FOR THE PRODUCTION THEREOF, PHARMACEUTICAL PREPARATIONS BASED ON THESE COMPOUNDS AND THEIR USE
ATE265424T1 (en) * 2000-06-09 2004-05-15 Aventis Pharma Gmbh ACYLPHENYL UREA DERIVATIVES, METHOD FOR THEIR PRODUCTION AND THEIR USE AS MEDICINAL PRODUCTS
DE10116768A1 (en) * 2001-04-04 2002-10-10 Aventis Pharma Gmbh Hypoglycemic medicaments useful for treating type II diabetes contain new or known N-aroyl-N'-phenyl-urea derivatives which are glycogen phosphorylase a inhibitors
DE10125567B4 (en) * 2001-05-25 2004-08-26 Aventis Pharma Deutschland Gmbh Carbonamide substituted phenylurea derivatives, process for their preparation and their use as medicines
PE20021091A1 (en) * 2001-05-25 2003-02-04 Aventis Pharma Gmbh DERIVATIVES OF PHENYLUREA SUBSTITUTED WITH CARBONAMIDE AND PROCEDURE FOR THEIR PREPARATION
IL164249A0 (en) * 2002-04-11 2005-12-18 Aventis Pharma Gmbh Acyl-3-carboxphenylurea derivatives, processes forpreparing them and their use
MXPA05000055A (en) * 2002-07-11 2005-04-08 Aventis Pharma Gmbh Urea-substituted and urethane-substituted acylureas, methods for the production thereof and their use as medicaments.
DE50312261D1 (en) * 2002-07-12 2010-02-04 Sanofi Aventis Deutschland HETEROCYCLICALLY SUBSTITUTED BENZOYL HYDROGEN, METHOD FOR THE PRODUCTION THEREOF AND THEIR USE AS A MEDICAMENT

Also Published As

Publication number Publication date
AU2004218267A1 (en) 2004-09-16
ATE386735T1 (en) 2008-03-15
DE10309929A1 (en) 2004-12-02
CO5690587A2 (en) 2006-10-31
CA2518322A1 (en) 2004-09-16
BRPI0408148A (en) 2006-03-01
EP1603895B1 (en) 2008-02-20
DE502004006253D1 (en) 2008-04-03
EP1603895A1 (en) 2005-12-14
JP2006519795A (en) 2006-08-31
ZA200506119B (en) 2006-11-29
DE10309929B4 (en) 2006-02-23
KR20050108487A (en) 2005-11-16
MA27745A1 (en) 2006-02-01
NO20054418L (en) 2005-09-23
WO2004078743A1 (en) 2004-09-16
CN1759109A (en) 2006-04-12
RU2005131011A (en) 2006-05-10
MXPA05009122A (en) 2005-10-20
PL377293A1 (en) 2006-01-23

Similar Documents

Publication Publication Date Title
TNSN06409A1 (en) Novel fluoroglycoside derivatives of pyrazoles, medicaments containing these compounds, and the use thereof
YU91002A (en) Acylphenyl urea derivatives, methods for the production thereof and use thereof as a medicament
IL176914A0 (en) Heterocyclically substituted 7-amino-4-quinolone-3-carboxylic acid derivatives, method for the production thereof and their use as medicaments
RS20050019A (en) Heterocyclically substituted benzoylureas,method for their production and their use as medicaments
MY148483A (en) 4,5-diphenyl-pyrimidinyl-oxy or-mercapto substituted carboxylic acids, method for the production and use thereof as medicaments
BG108318A (en) Carboxamide-substituted phenylurea derivatives and method for the production and use thereof as medicaments
IL173203A0 (en) Novel cyano thiazolides, methods for the production thereof, and use thereof as a medicament
MX2008014101A (en) 4,5-diphenyl-pyrimidinyl-amino substituted carboxylic acids, method for the production and use thereof as medicaments.
MXPA05010712A (en) Quinoline-2-one-derivatives for the treatment of airways diseases.
YU70901A (en) 1,4-benzothiazepine-1,1-dioxide derivatives substituted by sugar radicals, methods for the production thereof, medicaments containing these compounds and the use thereof
NO20085068L (en) Phenylamino-benzoxazole-substituted carboxylic acids, process for their preparation and use thereof as medicaments
JO2646B1 (en) Novel heterocyclic compounds which are active as inhibitors of beta-lactamases
MX2007006311A (en) Hydroxybiphenyl carboxylic acids and derivatives, method for producing the same and their use.
NO20050134L (en) Diphenyllazidide ions substituted with acid groups, process for their preparation, drugs containing these compounds and their use
WO2002055496A8 (en) Aryl piperidine and piperazine derivatives as inducers of ldl-receptor expression
IL176915A0 (en) Cycloalkyl substituted 7-amino-4-quinolone-3-carboxylic acid derivatives, method for the production thereof and their use as medicaments
SI1751093T1 (en) Substituted cyclohexylacetic acid derivatives
HRP20050779A2 (en) Supstituted benzoylureidopyridyl-piperidine and pyrrolidine carboxylic acid derivatives, method for the production thereof and the use thereof
BRPI0517734A (en) 1 - [(6,7-substituted alkoxyquinoxalinyl) aminocarbonyl] -4- (hetero) arylpiperazine derivatives
TNSN06233A1 (en) 7-phenylamino-4-quinolone-3-carboxylic acid derivatives, methods for production and use thereof as medicaments
MX2009005242A (en) 5, 6, or 7-substituted-3-(hetero)arylisoquinolinamine derivatives and therapeutic use thereof.
MA27649A1 (en) CARBONYLAMINO SUBSTITUTED ACYLPHENYLUREA DERIVATIVES, METHOD FOR THE PRODUCTION AND USE THEREOF.
MXPA05008331A (en) Substituted 3-(benzoylureido)-thiophene derivatives, method for the production and use thereof.
MXPA05008990A (en) Cycloalkyl-substituted alkanoic acid derivatives, methods for the production thereof, and use thereof as a medicament.
MXPA04001852A (en) C2-substituted indane-1-ones and their derivatives, method for their production and their use as medicaments.

Legal Events

Date Code Title Description
ODRP Renewal fee for the maintenance of a patent

Payment date: 20051229

Year of fee payment: 3

A1OB Publication of a patent application
OBST Application withdrawn