IS6069A - N-cýanómetýlamíð sem próteasalatar - Google Patents

N-cýanómetýlamíð sem próteasalatar

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Publication number
IS6069A
IS6069A IS6069A IS6069A IS6069A IS 6069 A IS6069 A IS 6069A IS 6069 A IS6069 A IS 6069A IS 6069 A IS6069 A IS 6069A IS 6069 A IS6069 A IS 6069A
Authority
IS
Iceland
Prior art keywords
cyanomethylamide
protease inhibitor
oxides
novel
pharmaceutically acceptable
Prior art date
Application number
IS6069A
Other languages
English (en)
Inventor
M. Bryant Clifford
T. Palmer James
M. Rydzewski Robert
L. Setti Eduardo
Tian Zong-Qiang
Venkatraman Shankar
Wang Dan-Xiong
Original Assignee
Axys Pharmaceuticals, Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Axys Pharmaceuticals, Inc. filed Critical Axys Pharmaceuticals, Inc.
Publication of IS6069A publication Critical patent/IS6069A/is

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    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/62—Oxygen or sulfur atoms
    • C07D213/70—Sulfur atoms
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    • C07C255/29—Carboxylic acid nitriles having cyano groups bound to acyclic carbon atoms containing cyano groups and singly-bound nitrogen atoms, not being further bound to other hetero atoms, bound to the same saturated acyclic carbon skeleton containing cyano groups and acylated amino groups bound to the carbon skeleton
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