IN2014CN03762A - - Google Patents
Info
- Publication number
- IN2014CN03762A IN2014CN03762A IN3762CHN2014A IN2014CN03762A IN 2014CN03762 A IN2014CN03762 A IN 2014CN03762A IN 3762CHN2014 A IN3762CHN2014 A IN 3762CHN2014A IN 2014CN03762 A IN2014CN03762 A IN 2014CN03762A
- Authority
- IN
- India
- Prior art keywords
- attachment
- please see
- please
- see
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
- C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
- C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
- C07D249/10—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D249/12—Oxygen or sulfur atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/4196—1,2,4-Triazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
- C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
- C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
- C07D249/10—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D249/14—Nitrogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Virology (AREA)
- Molecular Biology (AREA)
- AIDS & HIV (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Epidemiology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Enzymes And Modification Thereof (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Road Signs Or Road Markings (AREA)
- Pens And Brushes (AREA)
- Diaphragms For Electromechanical Transducers (AREA)
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US60422004P | 2004-08-25 | 2004-08-25 | |
US60421904P | 2004-08-25 | 2004-08-25 | |
US68635105P | 2005-05-31 | 2005-05-31 | |
PCT/US2005/030259 WO2006026356A2 (fr) | 2004-08-25 | 2005-08-25 | S-triazolyl $g(a)-mercaptoacetanildes tenant lieu d'inhibiteurs de la transcriptase inverse vih |
Publications (1)
Publication Number | Publication Date |
---|---|
IN2014CN03762A true IN2014CN03762A (fr) | 2015-09-25 |
Family
ID=36000576
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IN3762CHN2014 IN2014CN03762A (fr) | 2004-08-25 | 2005-08-25 |
Country Status (32)
Country | Link |
---|---|
US (8) | US7947721B2 (fr) |
EP (5) | EP2402011B1 (fr) |
JP (2) | JP4952943B2 (fr) |
KR (1) | KR101241716B1 (fr) |
CN (2) | CN101817793B (fr) |
AT (2) | ATE528001T1 (fr) |
AU (2) | AU2005280130C9 (fr) |
BR (2) | BRPI0514630B8 (fr) |
CA (1) | CA2578068C (fr) |
CY (2) | CY1112221T1 (fr) |
DK (1) | DK2135608T3 (fr) |
EA (2) | EA014737B1 (fr) |
EC (1) | ECSP077322A (fr) |
ES (2) | ES2380604T3 (fr) |
FR (1) | FR16C0031I2 (fr) |
HK (1) | HK1133582A1 (fr) |
HR (1) | HRP20130075T1 (fr) |
HU (1) | HUS1600034I1 (fr) |
IL (3) | IL181523A (fr) |
IN (1) | IN2014CN03762A (fr) |
LT (1) | LTC2135608I2 (fr) |
LU (1) | LU93169I2 (fr) |
ME (1) | ME01512B (fr) |
MX (1) | MX2007002236A (fr) |
NL (1) | NL300825I2 (fr) |
NZ (2) | NZ553534A (fr) |
PL (1) | PL2135608T3 (fr) |
PT (1) | PT2135608E (fr) |
RS (1) | RS52632B (fr) |
SG (2) | SG155246A1 (fr) |
SI (1) | SI2135608T1 (fr) |
WO (1) | WO2006026356A2 (fr) |
Families Citing this family (51)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA2578068C (fr) * | 2004-08-25 | 2011-08-09 | Ardea Biosciences, Inc. | S-triazolyl .alpha.-mercaptoacetanildes tenant lieu d'inhibiteurs de la transcriptase inverse vih |
WO2007050087A1 (fr) | 2004-08-25 | 2007-05-03 | Ardea Biosciences, Inc. | Acides N[S(4-aryltriazol-3-yl)α-mercaptoacétyl]-p-aminobenzoïques EN TANT QU'INHIBITEURS DE TRANSCRIPTASE INVERSE DE VIH |
EP2155692B1 (fr) | 2007-05-30 | 2015-06-17 | F. Hoffmann-La Roche AG | Inhibiteurs non nucléosidiques de transcriptase inverse |
WO2009030996A1 (fr) * | 2007-09-05 | 2009-03-12 | Coley Pharmaceutical Group, Inc. | Composés triazole utilisés comme agonistes du récepteur de type toll (tlr) |
MX2010005776A (es) * | 2007-11-27 | 2010-08-31 | Ardea Biosciences Inc | Nuevos compuestos y composiciones y metodos de uso. |
US8173690B2 (en) * | 2008-09-04 | 2012-05-08 | Ardea Biosciences, Inc. | Compounds, compositions and methods of using same for modulating uric acid levels |
US8242154B2 (en) | 2008-09-04 | 2012-08-14 | Ardea Biosciences, Inc. | Compounds, compositions and methods of using same for modulating uric acid levels |
MX2011002449A (es) * | 2008-09-04 | 2011-05-25 | Ardea Biosciences Inc | Compuestos, composiciones y métodos para utilizar los mismos para modular niveles de ácido úrico. |
WO2010048593A1 (fr) * | 2008-10-24 | 2010-04-29 | Ardea Biosciences, Inc. | Compositions comprenant l'acide 4-(2-(5-bromo-4-(1-cyclopropylnaphtalén-4-yl)-4h-1,2,4-triazol-3-yl- thio)acétamido-3-chlorobenzoïque et ses sels de qualité pharmaceutique |
WO2010048592A1 (fr) * | 2008-10-24 | 2010-04-29 | Ardea Biosciences, Inc. | Compositions comprenant l'acide 4-(2-(5-bromo-4-(1- cyclopropylnaphtalén-4-yl)-4h-1,2,4-triazol-3-ylthio)acétamido-3- chlorobenzoïque et ses sels de qualité pharmaceutique |
WO2010135536A2 (fr) | 2009-05-20 | 2010-11-25 | Ardea Biosciences, Inc. | Procédés pour moduler des taux d'acide urique |
CN102040546B (zh) * | 2009-10-10 | 2014-10-15 | 台州市华南医化有限公司 | 一种4-环丙基-1-异硫氰基萘的制备方法及中间体4-环丙基-1-萘甲醛肟/卤化物 |
EP2521716B1 (fr) * | 2010-01-08 | 2015-12-30 | Ardea Biosciences, Inc. | Formes polymorphes, cristallines et en mésophase, du 2-(5-bromo-4-(4-cyclopropylnaphtalène-1-yl)-4h-1,2,4-triazol-3-ylthio) acétate de sodium, et utilisations correspondantes |
US9402827B2 (en) | 2010-03-30 | 2016-08-02 | Ardea Biosciences, Inc. | Treatment of gout |
CA2802407C (fr) | 2010-06-15 | 2018-01-23 | Ardea Biosciences, Inc. | Traitement de la goutte et de l'hyperuricemie |
EP2582664A4 (fr) | 2010-06-16 | 2014-07-09 | Ardea Biosciences Inc | Phénylthioacétates, compositions et procédés d'application |
AR081930A1 (es) | 2010-06-16 | 2012-10-31 | Ardea Biosciences Inc | Compuestos de tioacetato |
CN101899013B (zh) * | 2010-07-12 | 2012-07-25 | 山东大学 | 2-(2-取代芳基-2h-1,2,4-三唑-3-巯基)乙酰胺衍生物及其制备方法与应用 |
US20130296345A1 (en) * | 2010-10-15 | 2013-11-07 | Ardea Biosciences, Inc. | Methods for treating hyperuricemia and related diseases |
RS55667B1 (sr) | 2010-12-30 | 2017-06-30 | Ardea Biosciences Inc | Polimorfne forme 2-(5-bromo-4-(4-cilkopropilnaftalen-1-il)-4h-1,2,4-triazol-3-iltio) sirćetne kiseline i njihova upotreba |
UA114304C2 (uk) | 2011-11-03 | 2017-05-25 | Ардеа Біосайєнсіс, Інк. | Спосіб зниження сироваткових рівнів сечової кислоти у людини |
AR091651A1 (es) * | 2012-07-03 | 2015-02-18 | Ardea Biosciences Inc | Elaboracion de acido 2-(5-bromo-4-(4-ciclopropilnaftalen-1-il)-4h-1,2,4-triazol-3-iltio)acetico |
CN105263913B (zh) * | 2013-06-14 | 2017-12-15 | 广东东阳光药业有限公司 | 硫代1,2,4‑三唑衍生物及其制备方法 |
CN103524440B (zh) * | 2013-10-15 | 2015-09-09 | 苏州鹏旭医药科技有限公司 | 痛风治疗药Lesinurad的制备方法及Lesinurad中间体 |
WO2015075561A2 (fr) * | 2013-11-22 | 2015-05-28 | Crystal Pharmatech Co., Ltd. | Formes cristallines de lésinurad et son sel de soude |
CN104557748A (zh) * | 2014-01-25 | 2015-04-29 | 广东东阳光药业有限公司 | 硫代-1,2,4-三唑衍生物的新的固体形态 |
CN105315218A (zh) * | 2014-07-17 | 2016-02-10 | 天津药物研究院 | 一种制备lesinurad中间体1-萘基三唑硫酮的方法 |
CN104341363B (zh) * | 2014-10-27 | 2016-08-17 | 张远强 | 一种硝基取代的三氮唑磺酰丙二酸类化合物、其制备方法及用途 |
CN104326993B (zh) * | 2014-10-27 | 2016-08-17 | 张远强 | 一种硝基取代三氮唑亚磺酰丙二酸类化合物、其制备方法及用途 |
CN104370842B (zh) * | 2014-10-27 | 2016-07-13 | 张远强 | 苯基取代的三氮唑磺酰丙二酸类化合物、其制备方法及用途 |
CN104341362B (zh) * | 2014-10-27 | 2016-07-13 | 张远强 | 三氮唑磺酰丙二酸类化合物、其制备方法及用途 |
CN104311498B (zh) * | 2014-10-27 | 2016-04-06 | 张远强 | 烷氧基取代的三氮唑磺酰丙二酸类化合物、其制备方法及用途 |
CN104370841B (zh) * | 2014-10-27 | 2016-07-13 | 张远强 | 三氮唑亚磺酰丙二酸类化合物、其制备方法及用途 |
CN104327000B (zh) * | 2014-10-27 | 2016-08-17 | 张远强 | 苯基取代的三氮唑亚磺酰丙二酸类化合物、其制备方法及用途 |
CN104341361B (zh) * | 2014-10-27 | 2017-01-11 | 张远强 | 一种腈基取代三氮唑亚磺酰丙二酸类化合物、其制备方法及用途 |
CN104326998B (zh) * | 2014-10-27 | 2016-08-17 | 张远强 | 苯基取代的三氮唑丙二酸类化合物、其制备方法及用途 |
EP3112334A1 (fr) | 2015-06-29 | 2017-01-04 | DPx Fine Chemicals Austria GmbH & CoKG | Procédé de fabrication de 1-cyclopropyl-naphthalènes |
CN104987311A (zh) * | 2015-06-30 | 2015-10-21 | 安徽万邦医药科技有限公司 | 一种[4-(4-环丙基萘-1-基)-5-硝基- 4h-[1,2,4]三唑-3-基硫烷基]-乙酸乙酯的制备方法及其中间体(5-硝基-4h-[1,2,4]三唑-3-基硫基)-乙酸乙酯 |
CN105153056A (zh) * | 2015-07-01 | 2015-12-16 | 安徽万邦医药科技有限公司 | 一种[5-溴-4-(4-环丙基萘-1-基)-4h-[1,2,4]三唑-3-基硫烷基]-乙酸甲酯的新制备方法 |
CN105017168A (zh) * | 2015-07-01 | 2015-11-04 | 安徽万邦医药科技有限公司 | 一种[5-溴-4-(4-环丙基萘-1-基)-4h-[1,2,4]三唑-3-基硫烷基]-乙酸甲酯的新制备方法 |
WO2017036884A1 (fr) | 2015-08-28 | 2017-03-09 | Sandoz Ag | Co-cristal de lésinurad, forme libre/ester éthylique de lésinurad |
CN105566237B (zh) * | 2016-03-01 | 2018-05-18 | 山东大学 | 一种治疗痛风的三唑巯乙酸类化合物的制备方法 |
CN109476611B (zh) | 2016-06-17 | 2022-08-23 | 南京明德新药研发有限公司 | 一种卤代化合物及其轴手性异构体 |
EP3281941B1 (fr) | 2016-08-11 | 2019-07-24 | Zentiva K.S. | Procédé de préparation d'acide 2-(5-bromo-4-(1-cyclopropylnaphtalén-4-yl)-4h-1,2,4-triazol-3-ythio) acétique |
EP3372592A1 (fr) | 2017-03-07 | 2018-09-12 | Zentiva, k.s. | Formes solides de sels d'amines de lesinurad |
US10351537B2 (en) * | 2017-03-10 | 2019-07-16 | Apotex Inc. | Processes for the preparation of lesinurad and intermediates thereof |
EP3315494A1 (fr) | 2017-04-19 | 2018-05-02 | Química Sintética, S.A. | Forme amorphe de lésinurad et ses procédés de préparation |
CN108947919B (zh) | 2017-05-17 | 2023-05-02 | 上海奥博生物医药股份有限公司 | 一种抗痛风药Lesinurad的新型制备方法及其关键中间体 |
WO2019001325A1 (fr) * | 2017-06-28 | 2019-01-03 | 苏州科睿思制药有限公司 | Forme cristalline xv de lésinurad et son procédé de préparation |
EP3498697A1 (fr) | 2017-12-12 | 2019-06-19 | Química Sintética, S.A. | Nouveaux sels et polymorphes de lesinurad |
CN117279880A (zh) | 2021-05-28 | 2023-12-22 | 住友化学株式会社 | 环烷基溴的制造方法 |
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CA2578068C (fr) | 2004-08-25 | 2011-08-09 | Ardea Biosciences, Inc. | S-triazolyl .alpha.-mercaptoacetanildes tenant lieu d'inhibiteurs de la transcriptase inverse vih |
WO2007050087A1 (fr) | 2004-08-25 | 2007-05-03 | Ardea Biosciences, Inc. | Acides N[S(4-aryltriazol-3-yl)α-mercaptoacétyl]-p-aminobenzoïques EN TANT QU'INHIBITEURS DE TRANSCRIPTASE INVERSE DE VIH |
MX2010005776A (es) | 2007-11-27 | 2010-08-31 | Ardea Biosciences Inc | Nuevos compuestos y composiciones y metodos de uso. |
WO2010048592A1 (fr) | 2008-10-24 | 2010-04-29 | Ardea Biosciences, Inc. | Compositions comprenant l'acide 4-(2-(5-bromo-4-(1- cyclopropylnaphtalén-4-yl)-4h-1,2,4-triazol-3-ylthio)acétamido-3- chlorobenzoïque et ses sels de qualité pharmaceutique |
WO2010048593A1 (fr) | 2008-10-24 | 2010-04-29 | Ardea Biosciences, Inc. | Compositions comprenant l'acide 4-(2-(5-bromo-4-(1-cyclopropylnaphtalén-4-yl)-4h-1,2,4-triazol-3-yl- thio)acétamido-3-chlorobenzoïque et ses sels de qualité pharmaceutique |
TWM377707U (en) | 2009-09-16 | 2010-04-01 | Nat Energy Technology Co Ltd | Assembly of power supply |
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