NL300825I2 - - Google Patents

Download PDF

Info

Publication number
NL300825I2
NL300825I2 NL300825C NL300825C NL300825I2 NL 300825 I2 NL300825 I2 NL 300825I2 NL 300825 C NL300825 C NL 300825C NL 300825 C NL300825 C NL 300825C NL 300825 I2 NL300825 I2 NL 300825I2
Authority
NL
Netherlands
Prior art keywords
hiv
mercaptoacetanilides
conr
triazolyl
useful
Prior art date
Application number
NL300825C
Other languages
English (en)
Original Assignee
Ardea Biosciences Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ardea Biosciences Inc filed Critical Ardea Biosciences Inc
Publication of NL300825I2 publication Critical patent/NL300825I2/nl

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
    • C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
    • C07D249/10—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D249/12—Oxygen or sulfur atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4196—1,2,4-Triazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/18—Antivirals for RNA viruses for HIV
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
    • C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
    • C07D249/10—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D249/14—Nitrogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Virology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • AIDS & HIV (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Road Signs Or Road Markings (AREA)
  • Pens And Brushes (AREA)
  • Diaphragms For Electromechanical Transducers (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
NL300825C 2004-08-25 2016-07-28 NL300825I2 (nl)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US60422004P 2004-08-25 2004-08-25
US60421904P 2004-08-25 2004-08-25
US68635105P 2005-05-31 2005-05-31
EP05790722A EP1789039B1 (en) 2004-08-25 2005-08-25 S-triazolyl alpha -mercaptoacetanildes as inhibitors of hiv reverse transcriptase
PCT/US2005/030259 WO2006026356A2 (en) 2004-08-25 2005-08-25 S-TRIAZOLYL α-MERCAPTOACETANILDES AS INHIBITORS OF HIV REVERSE TRANSCRIPTASE

Publications (1)

Publication Number Publication Date
NL300825I2 true NL300825I2 (nl) 2017-01-24

Family

ID=36000576

Family Applications (1)

Application Number Title Priority Date Filing Date
NL300825C NL300825I2 (nl) 2004-08-25 2016-07-28

Country Status (32)

Country Link
US (8) US7947721B2 (nl)
EP (5) EP2135608B8 (nl)
JP (2) JP4952943B2 (nl)
KR (1) KR101241716B1 (nl)
CN (2) CN101817793B (nl)
AT (2) ATE528001T1 (nl)
AU (2) AU2005280130C9 (nl)
BR (2) BRPI0520870B8 (nl)
CA (1) CA2578068C (nl)
CY (2) CY1112221T1 (nl)
DK (1) DK2135608T3 (nl)
EA (2) EA015846B1 (nl)
EC (1) ECSP077322A (nl)
ES (2) ES2380604T3 (nl)
FR (1) FR16C0031I2 (nl)
HK (1) HK1133582A1 (nl)
HR (1) HRP20130075T1 (nl)
HU (1) HUS1600034I1 (nl)
IL (3) IL181523A (nl)
IN (1) IN2014CN03762A (nl)
LT (1) LTC2135608I2 (nl)
LU (1) LU93169I2 (nl)
ME (1) ME01512B (nl)
MX (1) MX2007002236A (nl)
NL (1) NL300825I2 (nl)
NZ (2) NZ581376A (nl)
PL (1) PL2135608T3 (nl)
PT (1) PT2135608E (nl)
RS (1) RS52632B (nl)
SG (2) SG155246A1 (nl)
SI (1) SI2135608T1 (nl)
WO (1) WO2006026356A2 (nl)

Families Citing this family (51)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2007050087A1 (en) * 2004-08-25 2007-05-03 Ardea Biosciences, Inc. N[S(4-aryl-triazol-3-yl)α -mercaptoacetyl]-p-amino benozoic acids AS HIV REVERSE TRANSCRIPTASE INHIBITORS
WO2006026356A2 (en) 2004-08-25 2006-03-09 Ardea Biosciences, Inc. S-TRIAZOLYL α-MERCAPTOACETANILDES AS INHIBITORS OF HIV REVERSE TRANSCRIPTASE
KR101542629B1 (ko) 2007-05-30 2015-08-06 에프. 호프만-라 로슈 아게 비-뉴클레오사이드 역전사효소 억제제
WO2009030996A1 (en) * 2007-09-05 2009-03-12 Coley Pharmaceutical Group, Inc. Triazole compounds as toll-like receptor (tlr) agonists
SI2217577T1 (sl) * 2007-11-27 2014-11-28 Ardea Biosciences, Inc. Nove spojine in sestavki ter metode uporabe
EA201100441A1 (ru) 2008-09-04 2011-10-31 Ардеа Биосайнсиз, Инк. Соединения для коррекции уровня мочевой кислоты и способы их применения
US8242154B2 (en) 2008-09-04 2012-08-14 Ardea Biosciences, Inc. Compounds, compositions and methods of using same for modulating uric acid levels
US8173690B2 (en) 2008-09-04 2012-05-08 Ardea Biosciences, Inc. Compounds, compositions and methods of using same for modulating uric acid levels
WO2010048592A1 (en) * 2008-10-24 2010-04-29 Ardea Biosciences, Inc. Compositions comprising 4- (2- ( 5-br0m0-4- ( 1-cyclopropylnaphthalen-4-yl) -4h-1, 2, 4-triaz0l-3-ylthi0) acetamido -3-chlorobenzoic acid and pharmaceutically acceptable salts thereof
AR073964A1 (es) * 2008-10-24 2010-12-15 Ardea Biosciences Inc Composiciones que comprenden acido 4-(2-(5-bromo-4-(1-ciclopropilnaftalen -4-il) -4h- 1,2,4-triazol-3-il tio ) acetamido)-3-clorobenzoico y sus sales farmaceuticamente aceptables y metodos de preparacion y uso delos mismos
EP2432468A2 (en) 2009-05-20 2012-03-28 Ardea Biosciences, Inc. Methods of modulating uric acid levels
CN102040546B (zh) * 2009-10-10 2014-10-15 台州市华南医化有限公司 一种4-环丙基-1-异硫氰基萘的制备方法及中间体4-环丙基-1-萘甲醛肟/卤化物
KR20120104627A (ko) * 2010-01-08 2012-09-21 아디아 바이오사이언스즈 인크. 나트륨 2-(5-브로모-4-(4-시클로프로필나프탈렌-1-일)-4ｈ-1,2,4-트리아졸-3-일티오)아세테이트의 다형태, 결정질 및 중간상 형태 및 그의 용도
EP3659601A1 (en) 2010-03-30 2020-06-03 Ardea Biosciences, Inc. Treatment of gout
PT2582683T (pt) 2010-06-15 2018-05-25 Ardea Biosciences Inc Tratamento da gota e de hiperuricemia
AR081930A1 (es) 2010-06-16 2012-10-31 Ardea Biosciences Inc Compuestos de tioacetato
BR112012032193A2 (pt) 2010-06-16 2019-09-24 Ardea Biosciences Inc composto, composiçoes e métodos de uso de feniltioacetato
CN101899013B (zh) * 2010-07-12 2012-07-25 山东大学 2-(2-取代芳基-2h-1,2,4-三唑-3-巯基)乙酰胺衍生物及其制备方法与应用
EP2627331A4 (en) * 2010-10-15 2014-03-12 Ardea Biosciences Inc METHODS OF TREATING HYPERURICEMIA AND RELATED DISEASES
EA022301B1 (ru) 2010-12-30 2015-12-30 Ардеа Биосайнсиз, Инк. Полиморфные формы 2-(5-бром-4-(4-циклопропилнафталин-1-ил)-4h-1,2,4-триазол-3-илтио)уксусной кислоты и их применение
SG11201402016PA (en) 2011-11-03 2014-05-29 Ardea Biosciences Inc 3,4-di-substituted pyridine compound, methods of using and compositions comprising the same
AR091651A1 (es) * 2012-07-03 2015-02-18 Ardea Biosciences Inc Elaboracion de acido 2-(5-bromo-4-(4-ciclopropilnaftalen-1-il)-4h-1,2,4-triazol-3-iltio)acetico
WO2014198241A1 (en) * 2013-06-14 2014-12-18 Sunshine Lake Pharma Co., Ltd. Thio-1,2,4-triazole derivatives and method for preparing the same
CN103524440B (zh) * 2013-10-15 2015-09-09 苏州鹏旭医药科技有限公司 痛风治疗药Lesinurad的制备方法及Lesinurad中间体
EP3071554B1 (en) * 2013-11-22 2018-10-03 Crystal Pharmatech Co., Ltd. Crystalline forms of lesinurad
CN104557748A (zh) * 2014-01-25 2015-04-29 广东东阳光药业有限公司 硫代-1,2,4-三唑衍生物的新的固体形态
CN105315218A (zh) * 2014-07-17 2016-02-10 天津药物研究院 一种制备lesinurad中间体1-萘基三唑硫酮的方法
CN104326998B (zh) * 2014-10-27 2016-08-17 张远强 苯基取代的三氮唑丙二酸类化合物、其制备方法及用途
CN104370842B (zh) * 2014-10-27 2016-07-13 张远强 苯基取代的三氮唑磺酰丙二酸类化合物、其制备方法及用途
CN104311498B (zh) * 2014-10-27 2016-04-06 张远强 烷氧基取代的三氮唑磺酰丙二酸类化合物、其制备方法及用途
CN104341362B (zh) * 2014-10-27 2016-07-13 张远强 三氮唑磺酰丙二酸类化合物、其制备方法及用途
CN104341363B (zh) * 2014-10-27 2016-08-17 张远强 一种硝基取代的三氮唑磺酰丙二酸类化合物、其制备方法及用途
CN104341361B (zh) * 2014-10-27 2017-01-11 张远强 一种腈基取代三氮唑亚磺酰丙二酸类化合物、其制备方法及用途
CN104327000B (zh) * 2014-10-27 2016-08-17 张远强 苯基取代的三氮唑亚磺酰丙二酸类化合物、其制备方法及用途
CN104326993B (zh) * 2014-10-27 2016-08-17 张远强 一种硝基取代三氮唑亚磺酰丙二酸类化合物、其制备方法及用途
CN104370841B (zh) * 2014-10-27 2016-07-13 张远强 三氮唑亚磺酰丙二酸类化合物、其制备方法及用途
EP3112334A1 (en) 2015-06-29 2017-01-04 DPx Fine Chemicals Austria GmbH & CoKG Process for manufacturing 1-cyclopropyl-naphthalenes
CN104987311A (zh) * 2015-06-30 2015-10-21 安徽万邦医药科技有限公司 一种[4-(4-环丙基萘-1-基)-5-硝基- 4h-[1,2,4]三唑-3-基硫烷基]-乙酸乙酯的制备方法及其中间体(5-硝基-4h-[1,2,4]三唑-3-基硫基)-乙酸乙酯
CN105017168A (zh) * 2015-07-01 2015-11-04 安徽万邦医药科技有限公司 一种[5-溴-4-(4-环丙基萘-1-基)-4h-[1,2,4]三唑-3-基硫烷基]-乙酸甲酯的新制备方法
CN105153056A (zh) * 2015-07-01 2015-12-16 安徽万邦医药科技有限公司 一种[5-溴-4-(4-环丙基萘-1-基)-4h-[1,2,4]三唑-3-基硫烷基]-乙酸甲酯的新制备方法
WO2017036884A1 (en) 2015-08-28 2017-03-09 Sandoz Ag A lesinurad, free form / lesinurad ethyl ester co-crystal
CN105566237B (zh) * 2016-03-01 2018-05-18 山东大学 一种治疗痛风的三唑巯乙酸类化合物的制备方法
US10633351B2 (en) 2016-06-17 2020-04-28 Medshine Discovery Inc. Halogenated compound and axially chiral isomer thereof
EP3281941B1 (en) 2016-08-11 2019-07-24 Zentiva K.S. Process for preparing 2-(5-bromo-4-(1-cyclopropylnaphthalen-4-yl)-4h-1,2,4-triazol-3-ylthio)acetic acid
EP3372592A1 (en) 2017-03-07 2018-09-12 Zentiva, k.s. Solid forms of lesinurad amine salts
US10351537B2 (en) * 2017-03-10 2019-07-16 Apotex Inc. Processes for the preparation of lesinurad and intermediates thereof
EP3315494A1 (en) 2017-04-19 2018-05-02 Química Sintética, S.A. Amorphous form of lesinurad and processes for its preparation
CN108947919B (zh) 2017-05-17 2023-05-02 上海奥博生物医药股份有限公司 一种抗痛风药Lesinurad的新型制备方法及其关键中间体
WO2019001325A1 (zh) * 2017-06-28 2019-01-03 苏州科睿思制药有限公司 雷西纳得的晶型xv及其制备方法
EP3498697A1 (en) 2017-12-12 2019-06-19 Química Sintética, S.A. Novel salts and polymorphs of lesinurad
JPWO2022249788A1 (nl) 2021-05-28 2022-12-01

Family Cites Families (30)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2006A (en) * 1841-03-16 Clamp for crimping leather
US226186A (en) 1880-04-06 Car-coupling
US2009A (en) * 1841-03-18 Improvement in machines for boring war-rockets
US2008A (en) * 1841-03-18 Gas-lamp eok conducting gas pkom ah elevated buhner to one below it
JPS5641637B2 (nl) 1973-11-26 1981-09-29
US6832996B2 (en) * 1995-06-07 2004-12-21 Arthrocare Corporation Electrosurgical systems and methods for treating tissue
JPH07215940A (ja) 1994-01-27 1995-08-15 Torii Yakuhin Kk 抗ウイルス活性を有する化合物
CA2251368A1 (en) 1997-02-14 1998-08-20 Bayer Corporation Amide derivatives as selective neuropeptide y receptor antagonists
US6245817B1 (en) * 1997-02-14 2001-06-12 Bayer Corporation NPY5 receptor antagonists and methods for using same
JPH10243033A (ja) * 1997-02-28 1998-09-11 Oki Electric Ind Co Ltd 復調装置
ES2361146T3 (es) * 1998-03-27 2011-06-14 Janssen Pharmaceutica Nv Derivados de la piramidina inhibitatoria de vih.
WO2000027850A2 (en) 1998-11-12 2000-05-18 Neurocrine Biosciences, Inc. Crf receptor antagonists and methods relating thereto
AU2217200A (en) * 1998-12-23 2000-07-12 Neurogen Corporation 2-amino-9-alkylpurines: gaba brain receptor ligands
ATE411286T1 (de) * 1998-12-25 2008-10-15 Shionogi & Co Aromatische heterocyclen mit hiv integrase inhibierenden eigenschaften
US6593077B2 (en) * 1999-03-22 2003-07-15 Special Materials Research And Technology, Inc. Method of making thin films dielectrics using a process for room temperature wet chemical growth of SiO based oxides on a substrate
CA2439820A1 (en) 2001-03-02 2002-09-12 Smithkline Beecham Corporation Benzophenones as inhibitors of reverse transcriptase
JO3429B1 (ar) 2001-08-13 2019-10-20 Janssen Pharmaceutica Nv مشتقات برميدينات مثبطة فيروس الايدز
AU2003222648A1 (en) 2002-05-13 2003-12-02 Eli Lilly And Company Multicyclic compounds for use as melanin concentrating hormone antagonists in the treatment of obesity and diabetes
CN1697650B (zh) 2002-08-23 2010-11-10 阿迪亚生命科学公司 非核苷类逆转录酶抑制剂
US7642277B2 (en) * 2002-12-04 2010-01-05 Boehringer Ingelheim International Gmbh Non-nucleoside reverse transcriptase inhibitors
CN102151270A (zh) 2003-02-07 2011-08-17 詹森药业有限公司 预防hiv感染的嘧啶衍生物
AP2006003517A0 (en) 2003-09-25 2006-02-28 Janssen Pharmaceutica Nv Hiv replication purine derivatives.
US20080031901A1 (en) * 2004-09-24 2008-02-07 Abbott Laboratories Sustained release monoeximic formulations of opioid and nonopioid analgesics
US7517998B2 (en) 2004-06-01 2009-04-14 Boehringer Ingelheim International Gmbh Non nucleoside reverse transcriptase inhibitors
WO2006026356A2 (en) * 2004-08-25 2006-03-09 Ardea Biosciences, Inc. S-TRIAZOLYL α-MERCAPTOACETANILDES AS INHIBITORS OF HIV REVERSE TRANSCRIPTASE
WO2007050087A1 (en) 2004-08-25 2007-05-03 Ardea Biosciences, Inc. N[S(4-aryl-triazol-3-yl)α -mercaptoacetyl]-p-amino benozoic acids AS HIV REVERSE TRANSCRIPTASE INHIBITORS
SI2217577T1 (sl) * 2007-11-27 2014-11-28 Ardea Biosciences, Inc. Nove spojine in sestavki ter metode uporabe
WO2010048592A1 (en) 2008-10-24 2010-04-29 Ardea Biosciences, Inc. Compositions comprising 4- (2- ( 5-br0m0-4- ( 1-cyclopropylnaphthalen-4-yl) -4h-1, 2, 4-triaz0l-3-ylthi0) acetamido -3-chlorobenzoic acid and pharmaceutically acceptable salts thereof
AR073964A1 (es) 2008-10-24 2010-12-15 Ardea Biosciences Inc Composiciones que comprenden acido 4-(2-(5-bromo-4-(1-ciclopropilnaftalen -4-il) -4h- 1,2,4-triazol-3-il tio ) acetamido)-3-clorobenzoico y sus sales farmaceuticamente aceptables y metodos de preparacion y uso delos mismos
TWM377707U (en) * 2009-09-16 2010-04-01 Nat Energy Technology Co Ltd Assembly of power supply

Also Published As

Publication number Publication date
AU2005280130A1 (en) 2006-03-09
LTPA2016024I1 (lt) 2016-09-12
IN2014CN03762A (nl) 2015-09-25
EP2135608B1 (en) 2011-10-12
US20100069645A1 (en) 2010-03-18
EP1789039A4 (en) 2009-08-05
CY1112221T1 (el) 2015-12-09
CN101083987A (zh) 2007-12-05
JP4952943B2 (ja) 2012-06-13
US20120283301A1 (en) 2012-11-08
IL181523A (en) 2013-12-31
EA200700488A1 (ru) 2007-08-31
EA015846B1 (ru) 2011-12-30
US20150094284A1 (en) 2015-04-02
ES2380604T3 (es) 2012-05-16
LU93169I2 (fr) 2016-10-10
EP1789039A2 (en) 2007-05-30
EP2402011A1 (en) 2012-01-04
IL181523A0 (en) 2007-07-04
IL219131A0 (en) 2012-06-28
KR101241716B1 (ko) 2013-03-08
NZ581376A (en) 2011-05-27
AU2005280130C1 (en) 2010-02-18
PL2135608T3 (pl) 2012-07-31
US20100081827A1 (en) 2010-04-01
AU2009217458A8 (en) 2009-10-29
EP2402011B1 (en) 2012-11-14
US20110313157A1 (en) 2011-12-22
CA2578068C (en) 2011-08-09
CY2016028I1 (el) 2016-12-14
HK1133582A1 (en) 2010-04-01
SG185992A1 (en) 2012-12-28
EA200901186A1 (ru) 2010-04-30
EA014737B1 (ru) 2011-02-28
JP5457472B2 (ja) 2014-04-02
WO2006026356A2 (en) 2006-03-09
US8003681B2 (en) 2011-08-23
AU2005280130B2 (en) 2009-09-10
US7947721B2 (en) 2011-05-24
ECSP077322A (es) 2007-04-26
EP1789039B1 (en) 2012-01-11
HUS1600034I1 (hu) 2016-09-28
CN101817793A (zh) 2010-09-01
ATE528001T1 (de) 2011-10-15
FR16C0031I1 (nl) 2016-09-23
AU2005280130C9 (en) 2010-03-04
FR16C0031I2 (fr) 2017-03-31
ATE540677T1 (de) 2012-01-15
EP2609917A1 (en) 2013-07-03
BRPI0520870B8 (pt) 2021-05-25
US20180002296A1 (en) 2018-01-04
ES2374773T3 (es) 2012-02-21
AU2009217458B2 (en) 2009-11-19
HRP20130075T1 (hr) 2013-02-28
JP2012077088A (ja) 2012-04-19
KR20070054694A (ko) 2007-05-29
JP2008510828A (ja) 2008-04-10
SI2135608T1 (sl) 2012-03-30
CN101817793B (zh) 2014-01-08
BRPI0514630A (pt) 2008-06-17
CY2016028I2 (el) 2016-12-14
MX2007002236A (es) 2007-07-09
WO2006026356A3 (en) 2006-08-10
EP2135608A1 (en) 2009-12-23
RS52632B (en) 2013-06-28
DK2135608T3 (da) 2012-01-23
EP2433633A1 (en) 2012-03-28
PT2135608E (pt) 2012-01-13
US20100267724A2 (en) 2010-10-21
LTC2135608I2 (lt) 2017-07-25
US20080176850A1 (en) 2008-07-24
BRPI0514630B8 (pt) 2021-05-25
ME01512B (me) 2014-04-20
NZ553534A (en) 2010-10-29
AU2009217458A1 (en) 2009-10-15
CA2578068A1 (en) 2006-03-09
BRPI0520870B1 (pt) 2020-11-10
EP2135608B8 (en) 2012-03-21
SG155246A1 (en) 2009-09-30
US8252828B2 (en) 2012-08-28
US8481581B2 (en) 2013-07-09
BRPI0514630B1 (pt) 2020-09-15
US20110190491A1 (en) 2011-08-04
IL201546A (en) 2013-10-31
CN101083987B (zh) 2011-01-26
US8946273B2 (en) 2015-02-03

Similar Documents

Publication Publication Date Title
FR16C0031I1 (nl)
USD482736S1 (en) Design craft kit construction component—leaf form
GB2371066B (en) Tubulars with expandable cells and locking mechanisms
WO2005032488A3 (en) 2,4-dioxo-3-quinazolinylaryl sulfonylureas
USD488195S1 (en) Craft kit construction component-leaf form with through-hole
DE602005011031D1 (en) Phosphoindole als hiv-inhibitoren
USD527056S1 (en) Craft kit construction component—tear-drop form with through-hole
UA89200C2 (ru) S-ТРИАЗОЛИЛ-б-МЕРКАПТОАЦЕТАНИЛИДЫ КАК ИНГИБИТОРЫ ОБРАТНОЙ ТРАНСКРИПТАЗЫ ВИЧ
USD475099S1 (en) Craft kit construction component-arm and hand form with through-hole
AP2005003248A0 (en) 4-(3,5-dicyanophenoxy) pyrazole derivatives for use as reverse transcriptase modulators in the treatment of I. A. HIV.
USD475098S1 (en) Craft kit construction component—leg form
WO2004096147A3 (en) Oxo-pyrimidine compounds
USD472406S1 (en) Table
AR028458A1 (es) Un estuche de combinacion usado en el tratamiento del paludismo
RU2006146820A (ru) Средство связи
TH54449EX (th) อุปกรณ์ควบคุมไร้สาย
JP2003334596A5 (nl)
AP2005003429A0 (en) 5,7-Diaminopyrazolo Ä4,3-DÜ pyrimidines useful in the treatment of hypertension.