IN2012DN05069A - - Google Patents

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Publication number
IN2012DN05069A
IN2012DN05069A IN5069DEN2012A IN2012DN05069A IN 2012DN05069 A IN2012DN05069 A IN 2012DN05069A IN 5069DEN2012 A IN5069DEN2012 A IN 5069DEN2012A IN 2012DN05069 A IN2012DN05069 A IN 2012DN05069A
Authority
IN
India
Prior art keywords
sample
pathogen
trained personnel
pathogens
present
Prior art date
Application number
Other languages
English (en)
Inventor
Ido Bachelet
Joseph Joel Pollak
Daniel Levner
Yonatan Bilu
Noam Yorav-Raphael
Original Assignee
Parasight Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Parasight Ltd filed Critical Parasight Ltd
Publication of IN2012DN05069A publication Critical patent/IN2012DN05069A/en

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Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B01L3/502715—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by interfacing components, e.g. fluidic, electrical, optical or mechanical interfaces
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10—Investigating individual particles
    • G01N15/14—Optical investigation techniques, e.g. flow cytometry
    • G01N15/1429—Signal processing
    • G01N15/1433—Signal processing using image recognition
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
    • G01N21/21—Polarisation-affecting properties
    • G01N21/23—Bi-refringence
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
    • G01N21/59—Transmissivity
    • G01N21/5907—Densitometers
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64—Fluorescence; Phosphorescence
    • G01N21/645—Specially adapted constructive features of fluorimeters
    • G01N21/6456—Spatial resolved fluorescence measurements; Imaging
    • G01N21/6458—Fluorescence microscopy
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/0809—Geometry, shape and general structure rectangular shaped
    • B01L2300/0816—Cards, e.g. flat sample carriers usually with flow in two horizontal directions
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/0861—Configuration of multiple channels and/or chambers in a single devices
    • B01L2300/0864—Configuration of multiple channels and/or chambers in a single devices comprising only one inlet and multiple receiving wells, e.g. for separation, splitting
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/01—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials specially adapted for biological cells, e.g. blood cells
    • G01N2015/016—White blood cells
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10—Investigating individual particles
    • G01N2015/1006—Investigating individual particles for cytology
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
    • G01N21/59—Transmissivity
    • G01N21/5907—Densitometers
    • G01N2021/5957—Densitometers using an image detector type detector, e.g. CCD
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64—Fluorescence; Phosphorescence
    • G01N2021/6417—Spectrofluorimetric devices
    • G01N2021/6419—Excitation at two or more wavelengths
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64—Fluorescence; Phosphorescence
    • G01N2021/6417—Spectrofluorimetric devices
    • G01N2021/6421—Measuring at two or more wavelengths
    • G—PHYSICS
    • G06—COMPUTING; CALCULATING OR COUNTING
    • G06V—IMAGE OR VIDEO RECOGNITION OR UNDERSTANDING
    • G06V2201/00—Indexing scheme relating to image or video recognition or understanding
    • G06V2201/03—Recognition of patterns in medical or anatomical images
    • G—PHYSICS
    • G06—COMPUTING; CALCULATING OR COUNTING
    • G06V—IMAGE OR VIDEO RECOGNITION OR UNDERSTANDING
    • G06V2201/00—Indexing scheme relating to image or video recognition or understanding
    • G06V2201/04—Recognition of patterns in DNA microarrays

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Analytical Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Biochemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Dispersion Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Hematology (AREA)
  • Clinical Laboratory Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Signal Processing (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Computer Vision & Pattern Recognition (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
IN5069DEN2012 2010-12-29 2011-12-29 IN2012DN05069A (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201061427809P 2010-12-29 2010-12-29
PCT/IL2011/000973 WO2012090198A2 (fr) 2010-12-29 2011-12-29 Appareil et procédé de détection automatique de pathogènes

Publications (1)

Publication Number Publication Date
IN2012DN05069A true IN2012DN05069A (fr) 2015-10-09

Family

ID=46380428

Family Applications (1)

Application Number Title Priority Date Filing Date
IN5069DEN2012 IN2012DN05069A (fr) 2010-12-29 2011-12-29

Country Status (3)

Country Link
US (3) US9522396B2 (fr)
IN (1) IN2012DN05069A (fr)
WO (1) WO2012090198A2 (fr)

Families Citing this family (53)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20120077206A1 (en) 2003-07-12 2012-03-29 Accelr8 Technology Corporation Rapid Microbial Detection and Antimicrobial Susceptibility Testing
CA2956645A1 (fr) 2003-07-12 2005-03-31 David A. Goldberg Biodetection sensible et rapide
US9522396B2 (en) 2010-12-29 2016-12-20 S.D. Sight Diagnostics Ltd. Apparatus and method for automatic detection of pathogens
US9434937B2 (en) 2011-03-07 2016-09-06 Accelerate Diagnostics, Inc. Rapid cell purification systems
US10254204B2 (en) 2011-03-07 2019-04-09 Accelerate Diagnostics, Inc. Membrane-assisted purification
WO2013098821A1 (fr) 2011-12-29 2013-07-04 Parasight Ltd. Procédés et systèmes de détection de pathogène dans un prélèvement biologique
US9677109B2 (en) 2013-03-15 2017-06-13 Accelerate Diagnostics, Inc. Rapid determination of microbial growth and antimicrobial susceptibility
WO2014188405A1 (fr) 2013-05-23 2014-11-27 Parasight Ltd. Procédé et système d'imagerie de prélèvement cellulaire
IL227276A0 (en) 2013-07-01 2014-03-06 Parasight Ltd A method and system for obtaining a monolayer of cells, for use specifically for diagnosis
WO2015029032A1 (fr) * 2013-08-26 2015-03-05 Parasight Ltd. Systèmes, procédés et produits programmes d'ordinateur de microscopie numérique
US9536304B2 (en) * 2013-08-30 2017-01-03 Dairy Quality Inc. Determining pathogens based on an image of somatic cells in a fluid sample
ES2552405B1 (es) * 2014-05-27 2016-09-14 Tecnología Marina Ximo, S.L. Sistema y método de detección de parásitos Anisakis en filetes de pescado
JP6692049B2 (ja) * 2014-07-29 2020-05-13 国立大学法人浜松医科大学 識別装置および識別方法
WO2016030897A1 (fr) * 2014-08-27 2016-03-03 S.D. Sight Diagnostics Ltd Système et procédé de calcul de variation de focalisation pour un microscope numérique
WO2016061754A1 (fr) * 2014-10-22 2016-04-28 中国科学院自动化研究所 Système de navigation d'imagerie moléculaire portable
US10625259B1 (en) 2014-11-26 2020-04-21 Medica Corporation Automated microscopic cell analysis
US11478789B2 (en) * 2014-11-26 2022-10-25 Medica Corporation Automated microscopic cell analysis
US20170328924A1 (en) 2014-11-26 2017-11-16 Ronald Jones Automated microscopic cell analysis
US12005441B1 (en) 2014-11-26 2024-06-11 Medica Corporation Automated microscopic cell analysis
US10253355B2 (en) 2015-03-30 2019-04-09 Accelerate Diagnostics, Inc. Instrument and system for rapid microorganism identification and antimicrobial agent susceptibility testing
US10023895B2 (en) * 2015-03-30 2018-07-17 Accelerate Diagnostics, Inc. Instrument and system for rapid microogranism identification and antimicrobial agent susceptibility testing
AU2016322966B2 (en) 2015-09-17 2021-10-14 S.D. Sight Diagnostics Ltd Methods and apparatus for detecting an entity in a bodily sample
USD786707S1 (en) * 2016-01-19 2017-05-16 Stem Arts Projects, Llc Wavelength scanning apparatus
EP3408653B1 (fr) * 2016-01-28 2024-01-17 Siemens Healthcare Diagnostics Inc. Procédés et appareil aptes à quantifier un échantillon à partir de multiples vues latérales
WO2017132169A1 (fr) * 2016-01-28 2017-08-03 Siemens Healthcare Diagnostics Inc. Méthodes et appareil de détection d'interférant dans un échantillon
CN108738339B (zh) * 2016-01-28 2022-02-01 西门子医疗保健诊断公司 用于对试样中的伪像进行分类的方法和装置
WO2017168411A1 (fr) * 2016-03-30 2017-10-05 S.D. Sight Diagnostics Ltd Dispositif de traitement d'images destiné à l'identification de parasites du sang
JP6942148B2 (ja) 2016-05-11 2021-09-29 エス．ディー．サイト ダイアグノスティクス リミテッド 試料に対する光学測定の実施
US11307196B2 (en) 2016-05-11 2022-04-19 S.D. Sight Diagnostics Ltd. Sample carrier for optical measurements
WO2018119105A1 (fr) * 2016-12-20 2018-06-28 Indevr, Inc. Expertise par module d'extension pour l'identification de pathogènes à l'aide de réseaux neuronaux modulaires
KR102291945B1 (ko) 2017-02-02 2021-08-23 패스트 코포레이션 미생물의 운동성 운동학의 분석 및 사용
KR101791029B1 (ko) * 2017-05-31 2017-10-27 주식회사 뷰노 원충성 감염병에 대한 피검체의 감염 여부를 판정하는 방법 및 이를 이용한 장치
JP7214729B2 (ja) 2017-11-14 2023-01-30 エス．ディー．サイト ダイアグノスティクス リミテッド 光学測定用試料収容器
US11047845B1 (en) 2017-11-15 2021-06-29 Medica Corporation Control material and methods for cell analyzers
EP3818356A4 (fr) * 2018-07-02 2022-04-13 Ortho-Clinical Diagnostics, Inc. Procédé et appareil pour sélectionner un emplacement de lecture d'image sur support de lame
CN110569856B (zh) * 2018-08-24 2020-07-21 阿里巴巴集团控股有限公司 样本标注方法及装置、损伤类别的识别方法及装置
JP7274605B2 (ja) * 2019-04-18 2023-05-16 フンダシオ インスティテュート デ サイエンセズ フォトニクス 個々の微生物の光学的調査のための流体装置
US11402331B2 (en) * 2019-05-08 2022-08-02 City University Of Hong Kong Imaging and manipulation of biological sample
US20220206007A1 (en) * 2019-05-24 2022-06-30 The Board Of Trustees Of The Leland Stanford Junior University A Spectral Imaging Platform For Infectious Disease Diagnosis
US20220218242A1 (en) * 2019-05-29 2022-07-14 Ohio State Innovation Foundation Methods and apparatus for making a determination about a presence or an absence of a parasite in a blood sample
AU2020370212A1 (en) 2019-10-22 2022-04-28 S.D. Sight Diagnostics Ltd Accounting for errors in optical measurements
EP4073508A1 (fr) 2019-12-12 2022-10-19 S.D. Sight Diagnostics Ltd. Détection de plaquettes dans un échantillon de sang
WO2021116957A1 (fr) 2019-12-12 2021-06-17 S.D. Sight Diagnostics Ltd Images microscopiques extra-focale d'un échantillon
AU2020400401A1 (en) 2019-12-12 2022-06-02 S.D. Sight Diagnostics Ltd Analyzing an analyte disposed within a medium
CN114787685A (zh) 2019-12-12 2022-07-22 思迪赛特诊断有限公司 人工生成彩色血液涂片图像
WO2021116960A1 (fr) 2019-12-12 2021-06-17 S.D. Sight Diagnostics Ltd Modèles de classification destinés à l'analyse d'un échantillon
WO2022009104A2 (fr) 2020-07-07 2022-01-13 S.D. Sight Diagnostics Ltd Focalisation d'un microscope au moyen d'images fluorescentes
US11914131B1 (en) * 2020-08-16 2024-02-27 Gregory Dimitrenko Optical testing system for detecting infectious disease, testing device, specimen collector and related methods
GB2600719B (en) * 2020-11-05 2023-10-11 Oxford Nanoimaging Ltd Fluorescence assay
CN113537306A (zh) * 2021-06-29 2021-10-22 复旦大学 一种基于渐进式成长元学习的图像分类方法
US20230129946A1 (en) * 2021-10-25 2023-04-27 Principia Life, LLC Smart material sample analysis
WO2023144713A1 (fr) 2022-01-25 2023-08-03 S.D. Sight Diagnostics Ltd Porte-échantillon destiné à être utilisé avec un échantillon organique
GB202218615D0 (en) 2022-12-12 2023-01-25 S D Sight Diagnostics Ltd System and method for analyzing bodily samples

Family Cites Families (345)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3603156A (en) 1970-02-04 1971-09-07 Gradko Glass Lab Inc Disposable dilution system
US3676076A (en) 1970-09-24 1972-07-11 Gradko Glass Lab Inc Disposable container
GB1324323A (en) 1971-02-05 1973-07-25 Image Analysing Computers Ltd Automatic focusing of an optical image
US3967056A (en) 1973-02-26 1976-06-29 Minolta Camera Kabushiki Kaisha Automatic focusing apparatus
US3916205A (en) 1973-05-31 1975-10-28 Block Engineering Differential counting of leukocytes and other cells
US4076419A (en) 1976-07-12 1978-02-28 Kleker Richard G Method and apparatus for hematology
US4209548A (en) 1976-11-01 1980-06-24 Rush-Presbyterian-St. Luke's Medical Center Method for the preparation of blood samples for automated analysis
DE2910875C2 (de) 1979-03-20 1985-11-14 Kernforschungszentrum Karlsruhe Gmbh, 7500 Karlsruhe Verfahren zur automatischen Scharfeinstellung
ES508295A0 (es) 1981-08-27 1983-06-16 Becton Dickinson Co "perfeccionamientos introducidos en un aparato para introducir reactivos en recipientes de recogida de muestras".
US4454235A (en) 1982-06-01 1984-06-12 Miles Laboratories, Inc. Capillary tube holder for liquid transfer in immunoassay
US4494479A (en) 1982-10-14 1985-01-22 Coulter Electronics, Inc. Slide preparation apparatus
ATE98300T1 (de) 1983-01-10 1993-12-15 Gen Probe Inc Verfahren zum aufspueren, identifizieren und quantifizieren von organismen und viren.
US4580895A (en) 1983-10-28 1986-04-08 Dynatech Laboratories, Incorporated Sample-scanning photometer
DE3574408D1 (en) 1984-05-15 1989-12-28 Lawrence Kass Single dye replacement for romanowsky plural dye variable compositions in human biopsy specimen constituent identifications
US4700298A (en) 1984-09-14 1987-10-13 Branko Palcic Dynamic microscope image processing scanner
JPS61198204A (ja) 1985-02-28 1986-09-02 Disco Abrasive Sys Ltd 顕微鏡のオ−トフオ−カス方法
US5164598A (en) 1985-08-05 1992-11-17 Biotrack Capillary flow device
US4761381A (en) 1985-09-18 1988-08-02 Miles Inc. Volume metering capillary gap device for applying a liquid sample onto a reactive surface
DE3707487A1 (de) 1986-05-16 1987-11-26 Reichert Optische Werke Ag Verfahren zur autofokussierung von mikroskopen und mikroskope mit einer autofokussierung
JPH0774856B2 (ja) 1986-10-16 1995-08-09 オリンパス光学工業株式会社 自動焦点調節方法
US4774192A (en) 1987-01-28 1988-09-27 Technimed Corporation A dry reagent delivery system with membrane having porosity gradient
US4849340A (en) 1987-04-03 1989-07-18 Cardiovascular Diagnostics, Inc. Reaction system element and method for performing prothrombin time assay
US6262798B1 (en) 1992-09-29 2001-07-17 Board Of Regents, The University Of Texas System Method and apparatus for direct spectrophotometric measurements in unaltered whole blood
US5001067A (en) 1989-09-18 1991-03-19 Nova Biomedical Corporation Determining the concentration of water soluble species in biological fluid
US5064282A (en) 1989-09-26 1991-11-12 Artel, Inc. Photometric apparatus and method for measuring hemoglobin
US5229265A (en) 1990-03-13 1993-07-20 Litron Laboratories Process for analyzing clastogenic agents
US5427959A (en) 1990-10-01 1995-06-27 Canon Kabushiki Kaisha Apparatus and method for measuring specimen
US5331958A (en) 1992-03-31 1994-07-26 University Of Manitoba Spectrophotometric blood analysis
US5430542A (en) 1992-04-10 1995-07-04 Avox Systems, Inc. Disposable optical cuvette
US5342790A (en) 1992-10-30 1994-08-30 Becton Dickinson And Company Apparatus for indirect fluorescent assay of blood samples
EP0613003B1 (fr) 1993-02-22 2000-04-26 Sysmex Corporation Réactif pour détecter des cellules infectées avec malaria et méthode pour détecter des cellules infectées avec malaria utilisant ce réactif
US5483055A (en) 1994-01-18 1996-01-09 Thompson; Timothy V. Method and apparatus for performing an automatic focus operation for a microscope
US6074789A (en) 1994-03-08 2000-06-13 Philips Electronics N.A. Corp. Method for producing phosphor screens, and color cathode ray tubes incorporating same
US5590660A (en) 1994-03-28 1997-01-07 Xillix Technologies Corp. Apparatus and method for imaging diseased tissue using integrated autofluorescence
US5782770A (en) 1994-05-12 1998-07-21 Science Applications International Corporation Hyperspectral imaging methods and apparatus for non-invasive diagnosis of tissue for cancer
JPH07325247A (ja) 1994-05-31 1995-12-12 Nikon Corp 自動合焦装置
ES2131838T3 (es) 1994-07-01 1999-08-01 Jeffrey H Price Sistema de autofoco para microscopia de exploracion.
US5932872A (en) 1994-07-01 1999-08-03 Jeffrey H. Price Autofocus system for scanning microscopy having a volume image formation
WO1996012981A1 (fr) 1994-10-21 1996-05-02 Kla Instruments Corporation Dispositif et procede de focalisation automatique destine a un microscope a haute resolution
WO1996013615A1 (fr) 1994-10-27 1996-05-09 Entremed, Inc. Identification d'une infection par cytometrie de flux
DE69417900T2 (de) 1994-11-17 1999-11-11 Chemunex Maisons Alfort Vorrichtung und Verfahren zum schnellen und hochempfindlichen Erkennen und Zählen von Mikroorganismen mittels Fluoreszenz
SE504193C2 (sv) 1995-04-21 1996-12-02 Hemocue Ab Kapillär mikrokyvett
US5985595A (en) 1995-06-07 1999-11-16 The University Of Connecticut Early detection of Borrelia infection
US6005964A (en) * 1996-01-24 1999-12-21 The Board Of Trustees Of The University Of Illinois Automatic machine vision microscope slide inspection system and method
KR0165522B1 (ko) 1996-05-23 1999-03-20 김광호 혈증성분 무혈진단을 위한 최적지점 검색장치및 이를 이용한 무혈진단기
EP1947442A3 (fr) 1997-05-05 2008-07-30 ChemoMetec A/S Procédé et dispositif de détermination des particules biologiques dans un échantillon liquide
US6074879A (en) 1997-06-23 2000-06-13 Bayer Corporation Synthetic polymer particles for use as standards and calibrators in flow cytometry
JPH1173903A (ja) 1997-08-28 1999-03-16 Jeol Ltd 走査電子顕微鏡のオートフォーカス方法
GB2329014A (en) 1997-09-05 1999-03-10 Colin Campbell Automated identification of tubercle bacilli
US6064474A (en) 1998-02-06 2000-05-16 Optical Sensors, Inc. Optical measurement of blood hematocrit incorporating a self-calibration algorithm
US20020028471A1 (en) 1998-02-20 2002-03-07 Oberhardt Bruce J. Cell analysis methods and apparatus
US6929953B1 (en) 1998-03-07 2005-08-16 Robert A. Levine Apparatus for analyzing biologic fluids
US6350613B1 (en) 1998-03-07 2002-02-26 Belton Dickinson & Co. Determination of white blood cell differential and reticulocyte counts
US5948686A (en) 1998-03-07 1999-09-07 Robert A. Leuine Method for performing blood cell counts
US6723290B1 (en) 1998-03-07 2004-04-20 Levine Robert A Container for holding biologic fluid for analysis
US6027695A (en) 1998-04-01 2000-02-22 Dupont Pharmaceuticals Company Apparatus for holding small volumes of liquids
KR20010083041A (ko) 1998-06-02 2001-08-31 추후 파수 도메인 반사측정과 배경 진폭 감소 및 보상을 사용한공초점 간섭 마이크로스코피용 방법 및 장치
US6101104A (en) 1998-06-04 2000-08-08 Hughes Electronics Corporation Predictive threshold synchronous rectifier control
IT1304854B1 (it) 1998-07-29 2001-04-05 Paolo Fazii Metodo di differenziazione cromatica dei microrganismi in fluorescenza
US6132685A (en) 1998-08-10 2000-10-17 Caliper Technologies Corporation High throughput microfluidic systems and methods
US6320979B1 (en) 1998-10-06 2001-11-20 Canon Kabushiki Kaisha Depth of field enhancement
US6340613B1 (en) 1998-11-12 2002-01-22 Micron Technology, Inc. Structural integrity enhancement of dielectric films
US6496260B1 (en) 1998-12-23 2002-12-17 Molecular Devices Corp. Vertical-beam photometer for determination of light absorption pathlength
JP2000199845A (ja) 1999-01-05 2000-07-18 Ricoh Co Ltd 自動合焦装置及び自動合焦方法
US6344340B1 (en) 1999-03-01 2002-02-05 Novus International, Inc. Viability assay for sporocyst-forming protozoa
WO2000070350A1 (fr) 1999-05-12 2000-11-23 Cme Telemetrix Inc. Procede et dispositif de mesure rapide de hba¿1c?
JP3901427B2 (ja) 1999-05-27 2007-04-04 松下電器産業株式会社 電子装置とその製造方法およびその製造装置
US7034883B1 (en) 1999-08-10 2006-04-25 Cellavision Ab Automatic focusing
US6949384B2 (en) 2001-12-21 2005-09-27 Spectromedical Inc. Method for monitoring degradation of Hb-based blood substitutes
US6611777B2 (en) 1999-11-23 2003-08-26 James Samsoondar Method for calibrating spectrophotometric apparatus
US6711516B2 (en) 1999-11-23 2004-03-23 Spectromedical Inc. Method for calibrating spectrophotometric apparatus
AU2610101A (en) 2000-01-06 2001-07-16 Caliper Technologies Corporation Methods and systems for monitoring intracellular binding reactions
JP2001199845A (ja) 2000-01-24 2001-07-24 Kao Corp 毛髪化粧料
US6836559B2 (en) 2000-03-09 2004-12-28 The Regents Of The University Of California Automated video-microscopic imaging and data acquisition system for colloid deposition measurements
AU2001251539A1 (en) 2000-04-11 2001-10-23 Cornell Research Foundation Inc. System and method for three-dimensional image rendering and analysis
US7668362B2 (en) 2000-05-03 2010-02-23 Aperio Technologies, Inc. System and method for assessing virtual slide image quality
US6711283B1 (en) 2000-05-03 2004-03-23 Aperio Technologies, Inc. Fully automatic rapid microscope slide scanner
US6799119B1 (en) 2000-05-15 2004-09-28 Colorado School Of Mines Method for detection of biological related materials using biomarkers
DK1287502T3 (da) 2000-05-23 2009-02-02 Munroe Chirnomas Fremgangsmåde og apparat til opbevaring af slanger i en anordning til håndtering af artikler
US6554788B1 (en) 2000-06-02 2003-04-29 Cobe Cardiovascular, Inc. Hematocrit sampling system
US7630063B2 (en) 2000-08-02 2009-12-08 Honeywell International Inc. Miniaturized cytometer for detecting multiple species in a sample
JP2003535330A (ja) 2000-06-02 2003-11-25 メディコメトリクス アンパーツゼルスカブ 生物試料の分類のための方法及びシステム
US6632681B1 (en) 2000-07-24 2003-10-14 Ey Laboratories Reagent delivery device and method of use
US6819408B1 (en) * 2000-09-27 2004-11-16 Becton, Dickinson And Company Method for obtaining a monolayer of desired particles in a liquid sample
US6448024B1 (en) 2000-10-03 2002-09-10 Roche Diagnostics Corporation Method, reagent, cartridge, and device for determining fibrinogen
US20100261159A1 (en) 2000-10-10 2010-10-14 Robert Hess Apparatus for assay, synthesis and storage, and methods of manufacture, use, and manipulation thereof
DE10051806A1 (de) 2000-10-18 2002-04-25 Bayer Ag Verfahren zur Charakterisierung, Identifizierung und Kennzeichnung von mikrobiellen Mischungen
US7027628B1 (en) 2000-11-14 2006-04-11 The United States Of America As Represented By The Department Of Health And Human Services Automated microscopic image acquisition, compositing, and display
US7155049B2 (en) 2001-01-11 2006-12-26 Trestle Acquisition Corp. System for creating microscopic digital montage images
EP1349493A2 (fr) 2001-01-12 2003-10-08 The General Hospital Corporation Systeme et procede permettant l'etalonnage et la mise en image simultanes d'un milieu
JP4937457B2 (ja) 2001-03-01 2012-05-23 オリンパス株式会社 顕微鏡制御装置、顕微鏡制御システム、顕微鏡の制御方法、プログラム、及び記録媒体
US6898451B2 (en) 2001-03-21 2005-05-24 Minformed, L.L.C. Non-invasive blood analyte measuring system and method utilizing optical absorption
US6519355B2 (en) 2001-03-28 2003-02-11 Alan C. Nelson Optical projection imaging system and method for automatically detecting cells having nuclear and cytoplasmic densitometric features associated with disease
EP1381229B1 (fr) 2001-03-30 2008-12-10 National Institute of Advanced Industrial Science and Technology Camera de microscope omnifocale en temps reel
US7132636B1 (en) 2001-07-06 2006-11-07 Palantyr Research, Llc Imaging system and methodology employing reciprocal space optical design
US7151246B2 (en) 2001-07-06 2006-12-19 Palantyr Research, Llc Imaging system and methodology
US7248716B2 (en) 2001-07-06 2007-07-24 Palantyr Research, Llc Imaging system, methodology, and applications employing reciprocal space optical design
US6872930B2 (en) 2003-03-31 2005-03-29 Palantyr Research, Llc Imaging system and methodology employing reciprocal space optical design
US7338168B2 (en) 2001-07-06 2008-03-04 Palantyr Research, Llc Particle analyzing system and methodology
US6664528B1 (en) 2001-07-06 2003-12-16 Palantyr Research, Llc Imaging system and methodology employing reciprocal space optical design
US7863552B2 (en) 2001-07-06 2011-01-04 Palantyr Research Llc Digital images and related methodologies
US6884983B2 (en) 2002-06-10 2005-04-26 Palantyr Research, Llc Imaging system for examining biological material
US7439478B2 (en) 2001-07-06 2008-10-21 Palantyr Research, Llc Imaging system, methodology, and applications employing reciprocal space optical design having at least one pixel being scaled to about a size of a diffraction-limited spot defined by a microscopic optical system
US7385168B2 (en) 2001-07-06 2008-06-10 Palantyr Research, Llc Imaging system, methodology, and applications employing reciprocal space optical design
US7288751B2 (en) 2001-07-06 2007-10-30 Palantyr Research, Llc Imaging system, methodology, and applications employing reciprocal space optical design
US7105795B2 (en) 2001-07-06 2006-09-12 Palantyr Research, Llc Imaging system, methodology, and applications employing reciprocal space optical design
JP4751535B2 (ja) 2001-07-26 2011-08-17 シスメックス株式会社 分画方法とそれを用いた血液分析装置
CN100354430C (zh) 2001-09-06 2007-12-12 基因描绘系统有限公司 一种检测样品中靶细胞或病毒的方法
US6989891B2 (en) 2001-11-08 2006-01-24 Optiscan Biomedical Corporation Device and method for in vitro determination of analyte concentrations within body fluids
SE0104443D0 (sv) 2001-12-28 2001-12-28 Hemocue Ab Analysis method and cuvette therefor
US7713474B2 (en) 2002-01-15 2010-05-11 Siemens Healthcare Diagnostics Inc. Liquid permeable composition in dry reagent devices
US7133547B2 (en) 2002-01-24 2006-11-07 Tripath Imaging, Inc. Method for quantitative video-microscopy and associated system and computer software program product
US7764821B2 (en) 2002-02-14 2010-07-27 Veridex, Llc Methods and algorithms for cell enumeration in a low-cost cytometer
AU2003217694A1 (en) 2002-02-22 2003-09-09 Bacus Research Laboratories, Inc. Focusable virtual microscopy apparatus and method
US20030161514A1 (en) 2002-02-28 2003-08-28 Curry Bo U. Bi-directional scanner control system
DE10246777A1 (de) 2002-03-21 2003-10-02 Endress & Hauser Wetzer Gmbh Vorrichtung zur Identifizierung eines Probennehmerbehälters
DE10217404A1 (de) 2002-04-18 2003-11-06 Leica Microsystems Autofokusverfahren für ein Mikroskop und System zum Einstellen des Fokus für ein Mikroskop
US6658143B2 (en) 2002-04-29 2003-12-02 Amersham Biosciences Corp. Ray-based image analysis for biological specimens
AU2003221584A1 (en) * 2002-05-01 2003-11-17 Chromos Molecular Systems, Inc. Methods for delivering nucleic acid molecules into cells and assessment thereof
US7272252B2 (en) 2002-06-12 2007-09-18 Clarient, Inc. Automated system for combining bright field and fluorescent microscopy
JP2004061942A (ja) 2002-07-30 2004-02-26 Nikon Corp 顕微鏡システム
US7177767B2 (en) 2002-10-18 2007-02-13 Abaxis, Inc. Systems and methods for the detection of short and long samples
JP3904505B2 (ja) 2002-10-22 2007-04-11 独立行政法人科学技術振興機構 マラリア感染診断剤及びマラリア原虫染色剤
DE10254685A1 (de) 2002-11-22 2004-06-03 Roche Diagnostics Gmbh Messeinrichtung zur optischen Untersuchung eines Testelements
US7490085B2 (en) 2002-12-18 2009-02-10 Ge Medical Systems Global Technology Company, Llc Computer-assisted data processing system and method incorporating automated learning
US20040128077A1 (en) * 2002-12-27 2004-07-01 Automated Cell, Inc. Method and apparatus for following cells
US20040132171A1 (en) 2003-01-06 2004-07-08 Peter Rule Wearable device for measuring analyte concentration
US20040253742A1 (en) 2003-01-31 2004-12-16 Affleck Rhett L. Automated imaging system and method
JP3869810B2 (ja) 2003-02-24 2007-01-17 株式会社堀場製作所 マイクロ血球カウンタ
US6955872B2 (en) 2003-03-20 2005-10-18 Coulter International Corp. Dye compositions which provide enhanced differential fluorescence and light scatter characteristics
US7346205B2 (en) * 2003-03-27 2008-03-18 Bartron Medical Imaging, Llc System and method for rapidly identifying pathogens, bacteria and abnormal cells
GB2401431B (en) 2003-04-02 2005-04-27 Amersham Biosciences Uk Ltd Method of, and computer software for, classification of cells into subpopulations
US7706862B2 (en) 2003-04-17 2010-04-27 Research Foundation Of The City University Of New York Detecting human cancer through spectral optical imaging using key water absorption wavelengths
US7329537B2 (en) 2003-04-17 2008-02-12 Nexcelom Bioscience, Llc Micro-pattern embedded plastic optical film device for cell-based assays
US7324694B2 (en) 2003-05-23 2008-01-29 International Remote Imaging Systems, Inc. Fluid sample analysis using class weights
US20040241677A1 (en) * 2003-05-29 2004-12-02 Lin Jeffrey S Techniques for automated diagnosis of cell-borne anomalies with digital optical microscope
EP1654346B1 (fr) 2003-06-12 2017-08-02 Accupath Diagnostic Laboratories, Inc. Procede et systeme pour l'analyse d'echantillons de cellules de forte densite
EP1649038B1 (fr) 2003-06-26 2014-07-02 Litron Laboratories Ltd. Procede de numeration de populations d'erythrocytes a micronoyaux avec distinction des plaquettes et / ou des amas associes aux plaquettes
CA2956645A1 (fr) 2003-07-12 2005-03-31 David A. Goldberg Biodetection sensible et rapide
KR100573621B1 (ko) 2003-07-18 2006-04-25 주식회사 디지탈바이오테크놀러지 세포 개체수 계수용 장치 및 그 제조방법
US7411680B2 (en) 2003-07-19 2008-08-12 Digital Bio Technology Device for counting micro particles
SE0302114D0 (sv) 2003-07-21 2003-07-21 Cellavision Ab Sätt att urskilja en objektkontur
US20050089208A1 (en) 2003-07-22 2005-04-28 Rui-Tao Dong System and method for generating digital images of a microscope slide
US7846738B2 (en) 2003-08-15 2010-12-07 President And Fellows Of Harvard College Study of polymer molecules and conformations with a nanopore
US20060233671A1 (en) 2003-09-19 2006-10-19 Beard Nigel P High density plate filler
US7998435B2 (en) 2003-09-19 2011-08-16 Life Technologies Corporation High density plate filler
JP4521490B2 (ja) 2003-11-21 2010-08-11 国立大学法人高知大学 類似パターン検索装置、類似パターン検索方法、類似パターン検索プログラム、および分画分離装置
US7030351B2 (en) 2003-11-24 2006-04-18 Mitutoyo Corporation Systems and methods for rapidly automatically focusing a machine vision inspection system
ES2332523T3 (es) 2004-02-09 2010-02-08 Rapid Pathogen Screening Inc. Metodo para el diagnostico rapido de blancos en fluidos corporales humanos.
US9176121B2 (en) 2004-02-13 2015-11-03 Roche Diagnostics Hematology, Inc. Identification of blood elements using inverted microscopy
JP4417143B2 (ja) 2004-03-11 2010-02-17 シスメックス株式会社 試料分析装置、プログラムおよびそのプログラムを記録した記録媒体
CA2559171A1 (fr) 2004-03-12 2005-09-29 Biotrove, Inc. Chargement d'ensembles d'echantillons de l'ordre du nanolitre
US7925070B2 (en) 2004-03-30 2011-04-12 Sysmex Corporation Method for displaying virtual slide and terminal device for displaying virtual slide
WO2005100539A2 (fr) 2004-04-07 2005-10-27 Levine, Robert, A. Chambre jetable pour l'analyse de liquides biologiques
EP1787156A1 (fr) 2004-06-11 2007-05-23 Nicholas Etienne Ross Diagnostic automatise de la malaria et d'autres infections
ATE479918T1 (de) 2004-06-17 2010-09-15 Koninkl Philips Electronics Nv Autofocus-mechanismus für ein spektroskopisches system
GB0414201D0 (en) 2004-06-24 2004-07-28 Fujifilm Electronic Imaging Method and apparatus for forming a multiple focus stack image
US8582924B2 (en) 2004-06-30 2013-11-12 Carl Zeiss Microimaging Gmbh Data structure of an image storage and retrieval system
US7456377B2 (en) 2004-08-31 2008-11-25 Carl Zeiss Microimaging Ais, Inc. System and method for creating magnified images of a microscope slide
US20060063185A1 (en) 2004-09-09 2006-03-23 Edouard Vannier Methods for detection of pathogens in red blood cells
US20060095241A1 (en) 2004-10-29 2006-05-04 Microsoft Corporation Systems and methods that utilize machine learning algorithms to facilitate assembly of aids vaccine cocktails
US7663738B2 (en) 2004-10-11 2010-02-16 Thermo Fisher Scientific Oy Method for automatically detecting factors that disturb analysis by a photometer
US8045782B2 (en) 2004-12-07 2011-10-25 Ge Healthcare Niagara, Inc. Method of, and apparatus and computer software for, implementing image analysis protocols
CA2589996C (fr) 2004-12-13 2012-02-21 Bayer Healthcare Llc Systeme de spectroscopie de transmission utilise pour la determination d'analytes dans un fluide corporel
MX2007006885A (es) 2004-12-13 2007-08-20 Bayer Healthcare Llc Sensor de prueba independiente.
EP1836490A2 (fr) 2004-12-14 2007-09-26 University Of The Witwatersrand Johannesburg Methode de diagnostic et de suivi des reservoirs de cellules morbides
US8140140B2 (en) 2005-02-14 2012-03-20 Optiscan Biomedical Corporation Analyte detection system for multiple analytes
US20060223052A1 (en) 2005-03-30 2006-10-05 Kimberly-Clark Worldwide, Inc. Technique for detecting microorganisms
US8145431B2 (en) 2005-04-01 2012-03-27 Advanced Medical Products Gmbh Body fluid testing component for simultaneous analyte detection
JP2006313151A (ja) 2005-04-07 2006-11-16 Sysmex Corp 血液分析装置、試料分析装置及びフローサイトメータ
JP2006301270A (ja) 2005-04-20 2006-11-02 Hitachi Kokusai Electric Inc オートフォーカス装置及びオートフォーカス方法
JP4667944B2 (ja) 2005-04-20 2011-04-13 シスメックス株式会社 画像作成装置
FR2884920B1 (fr) 2005-04-21 2007-08-10 Horiba Abx Sa Sa Dispositif et procede d'analyse multiparametrique d'elements microscopiques
US8263386B2 (en) 2005-05-06 2012-09-11 Samsung Electronics Co., Ltd. Digital bio disc (DBD), DBD driver apparatus, and assay method using the same
AT501944B1 (de) 2005-06-15 2007-06-15 Tissuegnostics Gmbh Verfahren zum segmentieren von leukozyten
US7417213B2 (en) 2005-06-22 2008-08-26 Tripath Imaging, Inc. Apparatus and method for rapid microscopic image focusing having a movable objective
EP1904826B1 (fr) 2005-07-14 2019-02-20 Battelle Memorial Institute Systèmes et procédés de détection biologique et chimique
US20070031056A1 (en) 2005-08-02 2007-02-08 Perz Cynthia B System for and method of focusing in automated microscope systems
JP2007040814A (ja) 2005-08-03 2007-02-15 Matsushita Electric Ind Co Ltd 吸光度測定用センサ及び吸光度測定方法
WO2007035633A2 (fr) 2005-09-16 2007-03-29 President & Fellows Of Harvard College Techniques et procedes de criblage
US7609369B2 (en) 2005-09-24 2009-10-27 Beckman Coulter, Inc. Methods of detection of iron deficiency and hemochromatosis
US7796797B2 (en) 2005-09-28 2010-09-14 Sysmex Corporation Apparatus for obtaining an image of a blood cell and method for obtaining an image of a blood cell
US7599893B2 (en) 2005-10-13 2009-10-06 Aureon Laboratories, Inc. Methods and systems for feature selection in machine learning based on feature contribution and model fitness
GB2431537B (en) 2005-10-20 2011-05-04 Amersham Biosciences Uk Ltd Method of processing an image
US7344890B2 (en) 2005-11-09 2008-03-18 Beckman Coulter, Inc. Method for discriminating platelets from red blood cells
US7933435B2 (en) 2005-11-21 2011-04-26 Vala Sciences, Inc. System, method, and kit for processing a magnified image of biological material to identify components of a biological object
WO2007063131A1 (fr) 2005-12-01 2007-06-07 Evotec Technologies Gmbh Dosage generique pour le suivi de l'endocytose
SE529536C2 (sv) 2006-01-25 2007-09-04 Hemocue Ab Metod för säkerställande av en provbehållares kvalitet
GB2435925A (en) * 2006-03-09 2007-09-12 Cytokinetics Inc Cellular predictive models for toxicities
SE530244C2 (sv) 2006-05-05 2008-04-08 Hemocue Ab Förfarande och system för kvantitativ hemoglobinbestämning
JP5040191B2 (ja) 2006-06-29 2012-10-03 富士通株式会社 マイクロインジェクション装置及び自動焦点調整方法
AT503862B1 (de) 2006-07-05 2010-11-15 Arc Austrian Res Centers Gmbh Pathogen-identifizierung anhand eines 16s oder 18s-rrna mikroarray
DE102006031177A1 (de) 2006-07-06 2008-01-10 Carl Zeiss Microimaging Gmbh Verfahren und Vorrichtung zur Erzeugung eines Bildes einer dünnen Schicht eines Objekts
SE530750C2 (sv) 2006-07-19 2008-09-02 Hemocue Ab En mätapparat, en metod och ett datorprogram
US7542137B2 (en) 2006-07-24 2009-06-02 University Of Ottawa Pathogen detection using coherent anti-stokes Raman scattering microscopy
US8067245B2 (en) 2006-07-24 2011-11-29 Medica Corporation Automated microscope for blood cell analysis
US8428331B2 (en) 2006-08-07 2013-04-23 Northeastern University Phase subtraction cell counting method
WO2008063135A1 (fr) 2006-11-24 2008-05-29 Agency For Science, Technology And Research Appareil pour traiter un échantillon dans une gouttelette de liquide et procédé d'utilisation
KR100844350B1 (ko) 2007-01-09 2008-07-07 주식회사 디지탈바이오테크놀러지 부유 혼합 미세입자 중 특정 미세입자를 광학적인 방법으로계수하기 위한 미세채널 칩 및 이를 이용한 미세입자 계수방법
CN101669143B (zh) 2007-01-11 2012-06-20 Mvm知识产权有限公司 利用自动图像分析测试机能微循环几何结构和速度分布
US7738094B2 (en) 2007-01-26 2010-06-15 Becton, Dickinson And Company Method, system, and compositions for cell counting and analysis
CA2677123A1 (fr) 2007-02-02 2008-08-07 Canadian Blood Services Procede de detection d'une contamination bacterienne a l'aide d'une diffusion de lumiere dynamique
CN101657840B (zh) 2007-02-05 2013-07-31 西门子医疗保健诊断公司 用于以显微术进行细胞分析的系统和方法
JP5105945B2 (ja) * 2007-04-19 2012-12-26 キヤノン株式会社 雲台装置及びその制御方法
DE102007021387A1 (de) 2007-05-04 2008-11-06 Eads Deutschland Gmbh Detektionsvorrichtung zur Detektion von biologischen Mikropartikeln wie Bakterien, Viren, Sporen, Pollen oder biologische Toxine, sowie Detektionsverfahren
US20080305514A1 (en) 2007-06-06 2008-12-11 Alcon Research, Ltd. Method for detecting microbes
KR100900511B1 (ko) 2007-07-23 2009-06-03 주식회사 디지탈바이오테크놀러지 유체분석용 칩
WO2009018473A1 (fr) 2007-07-31 2009-02-05 Micronics, Inc. Système de récupération d'écouvillon sanitaire, dispositif d'analyse microfluidique et procédés pour des analyses de diagnostic
US7936913B2 (en) 2007-08-07 2011-05-03 Nextslide Imaging Llc Network image review in clinical hematology
US7884254B2 (en) 2007-08-08 2011-02-08 Honeywell International Inc. Dehydrochlorination of hydrochlorofluorocarbons using pre-treated activated carbon catalysts
US8878923B2 (en) 2007-08-23 2014-11-04 General Electric Company System and method for enhanced predictive autofocusing
CN101387599B (zh) 2007-09-13 2011-01-26 深圳迈瑞生物医疗电子股份有限公司 一种区分粒子群落的方法及粒子分析仪
BRPI0815961A2 (pt) 2007-09-21 2018-02-14 Dow Global Technologies Inc pré-polímero terminado por isocianato, elastômero e processo para produzir um elastômero
WO2009041918A1 (fr) 2007-09-26 2009-04-02 Agency For Science, Technology And Research Procédé et système pour générer une image entièrement bien focalisée d'une grande scène tridimensionnelle
JP2009109198A (ja) 2007-10-26 2009-05-21 Arkray Inc 分析装置
KR101009447B1 (ko) 2007-11-12 2011-01-19 바디텍메드 주식회사 체액 샘플링, 전처리 및 투입장치 및 방법
US8125512B2 (en) 2007-11-16 2012-02-28 Samsung Electronics Co., Ltd. System and method for moving object selection in a handheld image capture device
EP2227711A4 (fr) * 2008-01-02 2014-01-22 Univ California Appareil de télémicroscopie à ouverture numérique élevée
US20090185734A1 (en) 2008-01-18 2009-07-23 Hemocue Ab Apparatus and method for analysis of particles in a liquid sample
JP4558047B2 (ja) 2008-01-23 2010-10-06 オリンパス株式会社 顕微鏡システム、画像生成方法、及びプログラム
US20110007178A1 (en) * 2008-03-12 2011-01-13 Koninklijke Philips Electronics N.V. Correction of spot area in measuring brightness of sample in biosensing device
ES2464572T3 (es) 2008-03-21 2014-06-03 Abbott Point Of Care, Inc. Método y aparato para determinar los índices de células sanguíneas rojas en una muestra de sangre utilizando la pigmentación intrínseca de la hemoglobina contenida en las células sanguíneas rojas
CN102027369B (zh) 2008-03-21 2018-10-26 艾博特健康公司 单独和在聚合凝块中检测和计数血小板的方法及设备
US8081303B2 (en) 2008-03-21 2011-12-20 Abbott Point Of Care, Inc. Method and apparatus for analyzing individual cells or particulates using fluorescent quenching and/or bleaching
ES2392380T3 (es) 2008-03-21 2012-12-10 Abbott Point Of Care, Inc. Procedimiento y aparato para determinar el hematocrito de una muestra de sangre utilizando la pigmentación intrínseca de la hemoglobina contenida en los glóbulos rojos
KR101561718B1 (ko) 2008-03-27 2015-10-19 프레지던트 앤드 펠로우즈 오브 하바드 칼리지 3차원 마이크로유체 장치
US8883491B2 (en) 2008-04-09 2014-11-11 Nexcelom Bioscience Llc Systems and methods for counting cells and biomolecules
US9017610B2 (en) 2008-04-25 2015-04-28 Roche Diagnostics Hematology, Inc. Method of determining a complete blood count and a white blood cell differential count
US8379944B2 (en) 2008-04-29 2013-02-19 Siemens Healthcare Diagnostics Inc. Identification, classification and counting of targets of interest in multispectral image data
WO2009157385A1 (fr) 2008-06-27 2009-12-30 古河電気工業株式会社 Procédé pour distinguer et trier des cellules et dispositif pour le réaliser
DE102008030874A1 (de) 2008-06-30 2010-01-07 Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. Verfahren und Vorrichtung zum Ermitteln einer Kontur und eines Mittelpunktes eines Objekts
US8491840B2 (en) 2008-07-14 2013-07-23 Samsung Electronics Co., Ltd. Microfluidic device, sample analyzing method using the same, and dilution ratio measuring method
US8385971B2 (en) 2008-08-19 2013-02-26 Digimarc Corporation Methods and systems for content processing
US8404198B2 (en) 2008-08-27 2013-03-26 Life Technologies Corporation Apparatus for and method of processing biological samples
CA2737116C (fr) * 2008-09-16 2019-01-15 Historx, Inc. Quantification reproductible de l'expression de biomarqueurs
US8280134B2 (en) 2008-09-22 2012-10-02 Cambridge Research & Instrumentation, Inc. Multi-spectral imaging including at least one common stain
JP5380973B2 (ja) 2008-09-25 2014-01-08 株式会社ニコン 画像処理装置及び画像処理プログラム
US8760756B2 (en) 2008-10-14 2014-06-24 Burnham Institute For Medical Research Automated scanning cytometry using chromatic aberration for multiplanar image acquisition
US8842900B2 (en) 2008-10-28 2014-09-23 Sysmex Corporation Specimen processing system and blood cell image classifying apparatus
EP2356465B1 (fr) 2008-11-13 2014-10-01 Beckman Coulter, Inc. Procédé de correction d'interférence de particules dans une mesure d'hémoglobine
CN101403650B (zh) 2008-11-21 2010-06-23 北京理工大学 差动共焦组合超长焦距测量方法与装置
US9041792B2 (en) 2008-11-27 2015-05-26 Koninklijke Philips N.V. Generation of a multicolour image of an unstained biological specimen
US20100157086A1 (en) 2008-12-15 2010-06-24 Illumina, Inc Dynamic autofocus method and system for assay imager
GB0900526D0 (en) 2009-01-14 2009-02-11 Perkinelmer Ltd Fluorescence microscopy methods and apparatus
JP5426181B2 (ja) 2009-01-21 2014-02-26 シスメックス株式会社 検体処理システム、細胞画像分類装置、及び検体処理方法
EP2216095A1 (fr) 2009-01-27 2010-08-11 Koninklijke Philips Electronics N.V. Dispositif microfluidiques pour numération formule sanguine
US9778188B2 (en) 2009-03-11 2017-10-03 Industrial Technology Research Institute Apparatus and method for detection and discrimination molecular object
US9470609B2 (en) 2009-04-09 2016-10-18 Koninklijke Philips N. V. Preparation of thin layers of a fluid containing cells for analysis
WO2010126903A1 (fr) 2009-04-27 2010-11-04 Constitution Medical Investors, Inc. Systèmes et méthodes d'analyse des liquides organiques
JP5424712B2 (ja) 2009-05-21 2014-02-26 キヤノン株式会社 画像処理装置及びその制御方法とプログラム
US20100300563A1 (en) 2009-05-27 2010-12-02 John Ramunas Modular device and method for moving fluids to and from a sample delivery element
US8891851B2 (en) 2009-07-15 2014-11-18 Glenn F. Spaulding Home healthcare management system and hardware
US8481303B2 (en) 2009-10-12 2013-07-09 Corning Incorporated Microfluidic device for cell culture
US8320655B2 (en) 2009-10-16 2012-11-27 General Electric Company Process and system for analyzing the expression of biomarkers in cells
SG187478A1 (en) 2009-10-19 2013-02-28 Ventana Med Syst Inc Imaging system and techniques
JP5394887B2 (ja) 2009-10-29 2014-01-22 オリンパス株式会社 顕微鏡装置および顕微鏡観察方法
CN102053051A (zh) 2009-10-30 2011-05-11 西门子公司 一种体液分析系统和用于体液分析的图像处理设备、方法
US20120058504A1 (en) 2009-10-30 2012-03-08 Simon Fraser University Methods and apparatus for dielectrophoretic shuttling and measurement of single cells or other particles in microfluidic chips
US9072772B2 (en) * 2009-11-05 2015-07-07 University of Pittsburgh—of the Commonwealth System of Higher Education Methods of treating disorders associated with protein aggregation
US9119573B2 (en) 2009-12-10 2015-09-01 Siemens Aktiengesellschaft Stent marker detection using a learning based classifier in medical imaging
US8748186B2 (en) 2009-12-22 2014-06-10 Abbott Laboratories Method for performing a blood count and determining the morphology of a blood smear
WO2011076413A1 (fr) 2009-12-22 2011-06-30 Universität Heidelberg Moyen et procédés permettant de détecter des plasmodies et de cribler ou de diagnostiquer une résistance au médicament ou une réactivité au médicament altérée des plasmodies
US8237786B2 (en) 2009-12-23 2012-08-07 Applied Precision, Inc. System and method for dense-stochastic-sampling imaging
WO2011082342A1 (fr) 2009-12-31 2011-07-07 Abbott Point Of Care, Inc. Procédé et appareil pour déterminer le volume globulaire moyen des globules rouges
US8906308B2 (en) 2010-01-15 2014-12-09 Abbott Laboratories Method for determining volume and hemoglobin content of individual red blood cells
WO2011091007A2 (fr) 2010-01-20 2011-07-28 Nexcelom Bioscience Llc Numération cellulaire et chambre d'échantillonnage et procédés de fabrication
KR101851117B1 (ko) 2010-01-29 2018-04-23 마이크로닉스 인코포레이티드. 샘플-투-앤서 마이크로유체 카트리지
JP5490568B2 (ja) 2010-02-26 2014-05-14 オリンパス株式会社 顕微鏡システム、標本観察方法およびプログラム
WO2011119678A2 (fr) * 2010-03-23 2011-09-29 California Institute Of Technology Microscopes optofluidiques super-résolution pour une imagerie en deux dimensions (2d) et en trois dimensions (3d)
SG174650A1 (en) 2010-03-31 2011-10-28 Agency Science Tech & Res A method of monitoring parasite development in blood
US8396269B2 (en) 2010-04-08 2013-03-12 Digital Pathco LLC Image quality assessment including comparison of overlapped margins
US8040517B1 (en) 2010-04-30 2011-10-18 General Electric Company Arc flash detection system and method
EP2585578A4 (fr) 2010-05-08 2014-01-08 Univ Twente Procédé simple et abordable pour l'immunophénotypage utilisant une préparation d'échantillons sur puce microfluidique avec cytométrie en image
WO2012000102A1 (fr) 2010-06-30 2012-01-05 The Governors Of The University Of Alberta Appareil et procédé pour une cytométrie cytofluidique exempte d'étiquette et basée sur la microscopie
US8813294B2 (en) 2010-07-07 2014-08-26 Clean & Go, Llc Grout and tile cleaning implement with replaceable member
US20120030618A1 (en) 2010-07-08 2012-02-02 Life Technologies Corporation Systems and methods for assigning attributes to a plurality of samples
US20150032671A9 (en) 2010-07-23 2015-01-29 General Electric Company Systems and methods for selecting and analyzing particles in a biological tissue
US10139613B2 (en) 2010-08-20 2018-11-27 Sakura Finetek U.S.A., Inc. Digital microscope and method of sensing an image of a tissue sample
US8933927B2 (en) 2010-09-02 2015-01-13 Samsung Electronics Co., Ltd. Display system with image conversion mechanism and method of operation thereof
US8351676B2 (en) 2010-10-12 2013-01-08 Sony Corporation Digital image analysis using multi-step analysis
US8542274B2 (en) 2010-10-18 2013-09-24 Olympus America Inc. Wide field microscopic imaging system and method
USD655421S1 (en) 2010-11-03 2012-03-06 Life Technologies Corporation Cell counter
WO2012075263A1 (fr) 2010-12-03 2012-06-07 Abbott Point Of Care Inc. Dispositifs d'analyse avec dilution d'échantillon et vérification de dilution intégrées et leurs procédés d'utilisation
US9522396B2 (en) 2010-12-29 2016-12-20 S.D. Sight Diagnostics Ltd. Apparatus and method for automatic detection of pathogens
JP5331828B2 (ja) 2011-01-14 2013-10-30 株式会社日立ハイテクノロジーズ 荷電粒子線装置
EP2686828A1 (fr) 2011-03-14 2014-01-22 The University Of Warwick Analyse histologique
US8982206B2 (en) 2011-04-07 2015-03-17 Uwm Research Foundation, Inc. High speed microscope with narrow detector and pixel binning
US9064301B2 (en) 2011-04-14 2015-06-23 Abbott Point Of Care, Inc. Method and apparatus for compressing imaging data of whole blood sample analyses
CN104094099B (zh) 2011-04-15 2017-05-03 罗氏血液诊断股份有限公司 测量细胞体积和成份
TWI493505B (zh) 2011-06-20 2015-07-21 Mstar Semiconductor Inc 影像處理方法以及影像處理裝置
US10426356B2 (en) 2011-07-09 2019-10-01 Gauss Surgical, Inc. Method for estimating a quantity of a blood component in a fluid receiver and corresponding error
US9652655B2 (en) 2011-07-09 2017-05-16 Gauss Surgical, Inc. System and method for estimating extracorporeal blood volume in a physical sample
CA2842377C (fr) 2011-07-19 2019-08-27 Ovizio Imaging Systems N.V. Procede et systeme de detection de cellules cancereuses et/ou de classification de cellules dans un echantillon de cellules
JP6031513B2 (ja) 2011-07-22 2016-11-24 ロッシュ ダイアグノスティクス ヘマトロジー インコーポレイテッド 網赤血球の同定および測定
JP5959814B2 (ja) 2011-08-08 2016-08-02 ソニー株式会社 血液分析装置および血液分析方法
EP2758765B1 (fr) 2011-09-22 2020-08-12 FOCE Technology International B.V. Procédé de compteur optique de plaquettes
US9046473B2 (en) 2011-09-28 2015-06-02 Abbott Point Of Care, Inc. Method and apparatus for detecting the presence of intraerythrocytic parasites
US9526431B2 (en) 2011-10-19 2016-12-27 Biovotion Ag System for noninvasive optical measurements of physiological properties in tissue
TWI431264B (zh) 2011-10-20 2014-03-21 Lite On It Corp 光學偵測裝置及光學量測系統
US8885912B2 (en) 2011-11-03 2014-11-11 General Electric Company Generate percentage of positive cells for biomarkers by normalizing and autothresholding the image intensity produced by immunohistochemistry technique
WO2013098821A1 (fr) 2011-12-29 2013-07-04 Parasight Ltd. Procédés et systèmes de détection de pathogène dans un prélèvement biologique
EP2798352B1 (fr) 2011-12-30 2015-11-25 Abbott Point Of Care, Inc. Procédé et appareil d'identification automatisée de plaquettes dans échantillon de sang total à partir d'images de microscopie
WO2013158506A2 (fr) 2012-04-17 2013-10-24 Ehrenkranz Joel R L Dispositif pour effectuer un comptage sanguin, de cellules et/ou de pathogène et procédés pour utilisation de celui-ci
CN104507577B (zh) 2012-04-18 2017-08-08 拜奥法尔诊断有限责任公司 微点样装置
US20140315283A1 (en) 2012-05-09 2014-10-23 David A. Calderwood Sample cartridge and sample stage
US8873827B2 (en) 2012-06-29 2014-10-28 General Electric Company Determination of spatial proximity between features of interest in biological tissue
US8744165B2 (en) 2012-07-19 2014-06-03 Sony Corporation Method and apparatus for stain separation in digital pathology images
CN103580818B (zh) 2012-07-31 2018-08-03 中兴通讯股份有限公司 一种信道状态信息的反馈方法、基站和终端
JP5333635B1 (ja) 2012-08-23 2013-11-06 富士ゼロックス株式会社 画像処理装置、プログラム及び画像処理システム
JP5464244B2 (ja) 2012-08-24 2014-04-09 富士ゼロックス株式会社 画像処理装置、プログラム及び画像処理システム
EP2731051A1 (fr) 2012-11-07 2014-05-14 bioMérieux Procédé de bio-imagerie
US9400414B2 (en) 2012-11-19 2016-07-26 Raytheon Company Methods and apparatus for imaging without retro-reflection using a tilted image plane and structured relay optic
EP2927311B1 (fr) 2012-11-28 2019-11-20 Japan Science And Technology Agency Dispositif d'observation de cellule, méthode d'observation de cellule et programme correspondant
US20140170678A1 (en) 2012-12-17 2014-06-19 Leukodx Ltd. Kits, compositions and methods for detecting a biological condition
US9976963B2 (en) 2012-12-21 2018-05-22 Integrated Plasmonics Corporation Microcuvette cartridge
WO2014159692A1 (fr) 2013-03-13 2014-10-02 Tahoe Institute for Rural Health Research, LLC Instrument portable de surveillance de numération sanguine
WO2014159620A1 (fr) 2013-03-14 2014-10-02 Samuels Mark A Dispositif d'étalonnage codé et systèmes et procédés correspondants
WO2014188405A1 (fr) 2013-05-23 2014-11-27 Parasight Ltd. Procédé et système d'imagerie de prélèvement cellulaire
IL227276A0 (en) 2013-07-01 2014-03-06 Parasight Ltd A method and system for obtaining a monolayer of cells, for use specifically for diagnosis
WO2015029032A1 (fr) 2013-08-26 2015-03-05 Parasight Ltd. Systèmes, procédés et produits programmes d'ordinateur de microscopie numérique
JP6194791B2 (ja) 2013-12-27 2017-09-13 富士ゼロックス株式会社 画像処理装置及びプログラム
WO2016030897A1 (fr) 2014-08-27 2016-03-03 S.D. Sight Diagnostics Ltd Système et procédé de calcul de variation de focalisation pour un microscope numérique
JP6352750B2 (ja) 2014-09-26 2018-07-04 シスメックス株式会社 血液分析装置および血液分析方法
EP3201311A4 (fr) 2014-09-29 2018-06-20 Chipcare Corporation Procédés et dispositifs pour la détection de cellules
US20170328924A1 (en) 2014-11-26 2017-11-16 Ronald Jones Automated microscopic cell analysis
US11478789B2 (en) 2014-11-26 2022-10-25 Medica Corporation Automated microscopic cell analysis
US10061972B2 (en) 2015-05-28 2018-08-28 Tokitae Llc Image analysis systems and related methods
JP6461739B2 (ja) 2015-07-28 2019-01-30 富士フイルム株式会社 画像処理装置及び内視鏡システム並びに画像処理装置の作動方法
DE102015113557B4 (de) 2015-08-17 2019-05-02 Gerresheimer Regensburg Gmbh Probenvorrichtung mit Referenzmarkierung
AU2016322966B2 (en) 2015-09-17 2021-10-14 S.D. Sight Diagnostics Ltd Methods and apparatus for detecting an entity in a bodily sample
US11175205B2 (en) 2015-11-02 2021-11-16 Biofire Diagnostics, Llc Sample preparation for difficult sample types
JP6559555B2 (ja) 2015-12-02 2019-08-14 株式会社日立エルジーデータストレージ 光計測方法および装置
WO2017168411A1 (fr) 2016-03-30 2017-10-05 S.D. Sight Diagnostics Ltd Dispositif de traitement d'images destiné à l'identification de parasites du sang
JP6942148B2 (ja) 2016-05-11 2021-09-29 エス．ディー．サイト ダイアグノスティクス リミテッド 試料に対する光学測定の実施
US10281386B2 (en) 2016-05-11 2019-05-07 Bonraybio Co., Ltd. Automated testing apparatus
US11307196B2 (en) 2016-05-11 2022-04-19 S.D. Sight Diagnostics Ltd. Sample carrier for optical measurements
EP3482189A4 (fr) 2016-07-08 2020-08-19 Medica Corporation Analyse automatisée de cellules microscopiques
US20190054466A1 (en) 2017-08-17 2019-02-21 Abbott Point Of Care Inc. Single-use test device for imaging blood cells
JP6505792B2 (ja) 2017-08-29 2019-04-24 富士フイルム株式会社 内視鏡用光源装置及び内視鏡システム
JP7214729B2 (ja) 2017-11-14 2023-01-30 エス．ディー．サイト ダイアグノスティクス リミテッド 光学測定用試料収容器
WO2019102277A1 (fr) 2017-11-23 2019-05-31 Sigtuple Technologies Private Limited Méthode et système de détermination de paramètres hématologiques dans un frottis sanguin périphérique
WO2019198094A1 (fr) 2018-04-09 2019-10-17 Sigtuple Technologies Private Limited Procédé et système d'estimation du nombre total de cellules sanguines dans un frottis sanguin
JP2019195304A (ja) 2018-05-10 2019-11-14 学校法人順天堂 画像解析方法、装置、コンピュータプログラム、及び深層学習アルゴリズムの生成方法
AU2020370212A1 (en) 2019-10-22 2022-04-28 S.D. Sight Diagnostics Ltd Accounting for errors in optical measurements
WO2021188569A1 (fr) 2020-03-17 2021-09-23 Detect, Inc. Test de diagnostic rapide avec emballage coque

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US9522396B2 (en) 2016-12-20
WO2012090198A2 (fr) 2012-07-05
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US12005443B2 (en) 2024-06-11
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