IL90062A - History of pyridonecarboxylic acid, their preparation and pharmaceutical preparations containing them - Google Patents
History of pyridonecarboxylic acid, their preparation and pharmaceutical preparations containing themInfo
- Publication number
- IL90062A IL90062A IL9006289A IL9006289A IL90062A IL 90062 A IL90062 A IL 90062A IL 9006289 A IL9006289 A IL 9006289A IL 9006289 A IL9006289 A IL 9006289A IL 90062 A IL90062 A IL 90062A
- Authority
- IL
- Israel
- Prior art keywords
- group
- amino
- cis
- compound
- oxo
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/48—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
- C07D215/54—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 3
- C07D215/56—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 3 with oxygen atoms in position 4
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Oncology (AREA)
- Pharmacology & Pharmacy (AREA)
- Communicable Diseases (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Pyridine Compounds (AREA)
- Quinoline Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Hydrogenated Pyridines (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP10462588 | 1988-04-27 | ||
JP29698488 | 1988-11-24 |
Publications (2)
Publication Number | Publication Date |
---|---|
IL90062A0 IL90062A0 (en) | 1989-12-15 |
IL90062A true IL90062A (en) | 1994-10-07 |
Family
ID=26445063
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IL9006289A IL90062A (en) | 1988-04-27 | 1989-04-24 | History of pyridonecarboxylic acid, their preparation and pharmaceutical preparations containing them |
Country Status (26)
Country | Link |
---|---|
US (4) | US5587386A (ru) |
EP (1) | EP0341493B1 (ru) |
JP (5) | JP2714597B2 (ru) |
KR (1) | KR0184614B1 (ru) |
CN (1) | CN1033751C (ru) |
AT (1) | ATE182145T1 (ru) |
AU (1) | AU625414B2 (ru) |
BG (1) | BG61122B2 (ru) |
CA (1) | CA1340801C (ru) |
DE (1) | DE68929030T2 (ru) |
DK (1) | DK175467B1 (ru) |
ES (1) | ES2135372T3 (ru) |
FI (1) | FI96947C (ru) |
GR (1) | GR3031365T3 (ru) |
HK (1) | HK1002108A1 (ru) |
HU (1) | HU211136A9 (ru) |
IL (1) | IL90062A (ru) |
LV (1) | LV10092B (ru) |
MY (1) | MY105136A (ru) |
NO (1) | NO175939C (ru) |
NZ (1) | NZ228893A (ru) |
PT (1) | PT90377B (ru) |
RU (1) | RU2075475C1 (ru) |
SG (1) | SG48036A1 (ru) |
UA (1) | UA29378C2 (ru) |
YU (1) | YU48432B (ru) |
Families Citing this family (42)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
IL90062A (en) * | 1988-04-27 | 1994-10-07 | Daiichi Seiyaku Co | History of pyridonecarboxylic acid, their preparation and pharmaceutical preparations containing them |
JPH0674261B2 (ja) * | 1988-06-21 | 1994-09-21 | 塩野義製薬株式会社 | キノロンカルボン酸誘導体 |
CA1336090C (en) * | 1988-08-31 | 1995-06-27 | Isao Hayakawa | Spiro-substituted cyclic amines of quinolone derivatives |
CN1054980A (zh) * | 1990-02-19 | 1991-10-02 | 杏林制药株式会社 | 具有旋光活性的8-甲氧基喹诺酮羧酸衍生物,它们的制备方法以及它们的中间体 |
MY109714A (en) * | 1990-10-18 | 1997-04-30 | Daiichi Seiyaku Co | Process for preparing 8-chloroquinolone derivatives |
WO1992021659A1 (en) * | 1991-05-28 | 1992-12-10 | Daiichi Pharmaceutical Co., Ltd. | Pyridonecarboxylic acid derivative |
JPH0678335B2 (ja) * | 1991-06-19 | 1994-10-05 | ファイザー・インコーポレーテッド | アザスピロキノロン化合物、その製法および抗菌組成物 |
KR960011370B1 (ko) * | 1991-12-31 | 1996-08-22 | 재단법인 한국화학연구소 | 스피로알킬아민 유도체와 그의 제조방법 |
NO301165B1 (no) * | 1992-12-25 | 1997-09-22 | Daiichi Seiyaku Co | Bicykliske aminderivater og antibakterielle midler inneholdende disse |
ZA946853B (en) * | 1993-09-10 | 1995-04-24 | Daiichi Seiyaku Co | Crystals of antimicrobial compound. |
WO1996002512A1 (fr) * | 1994-07-18 | 1996-02-01 | Ube Industries, Ltd. | Acide du type trifluoromethylquinoleinecarboxylique |
ATE239720T1 (de) * | 1995-02-02 | 2003-05-15 | Daiichi Seiyaku Co | Heterozyklische verbindungen |
ATE240312T1 (de) * | 1995-02-07 | 2003-05-15 | Daiichi Seiyaku Co | Heterocyclische spiroderivate |
JPH09124556A (ja) | 1995-08-30 | 1997-05-13 | Dai Ichi Seiyaku Co Ltd | ハロゲン化シクロプロパン誘導体の製造方法 |
CA2238765A1 (en) * | 1995-11-22 | 1997-05-29 | Satoru Miyauchi | Substituted aminocycloalkylpyrrolidine derivatives |
US6121285A (en) | 1995-11-22 | 2000-09-19 | Daiichi Pharmaceutical Co., Ltd. | Substituted aminocycloalkylpyrrolidine derivatives and cis-substituted aminocycloalkylpyrrolidine derivatives |
WO1997029102A1 (fr) * | 1996-02-09 | 1997-08-14 | Toyama Chemical Co., Ltd. | Derives de l'acide quinolonecarboxylique et leurs sels |
TW425394B (en) * | 1996-04-24 | 2001-03-11 | Daiichi Seiyaku Co | Antimicrobial quinolone derivatives having 3-(N-cycloalkyl) aminomethylpyrrolidine group |
WO1998024781A1 (fr) * | 1996-12-04 | 1998-06-11 | Daiichi Pharmaceutical Co., Ltd. | Derives d'aminomethylpyrrolidine substitue |
EP1134219B1 (en) | 1998-11-24 | 2005-06-15 | Daiichi Pharmaceutical Co., Ltd. | Cycloalkyl-substituted aminomethylpyrrolidine derivatives |
RU2255938C2 (ru) | 1999-03-10 | 2005-07-10 | Дайити Фармасьютикал Ко., Лтд. | Производные аминометилпирролидина, имеющие ароматические заместители |
EP2275141A1 (en) | 1999-03-17 | 2011-01-19 | Daiichi Pharmaceutical Co., Ltd. | Tastemasked pharmaceutical compositions |
MXPA02007667A (es) | 2000-02-09 | 2003-04-14 | Daiichi Seiyaku Co | Agentes antibacterianos antiacidos-resistentes que contienen acidos piridoncarboxilicos como el ingrediente activo. |
AR027761A1 (es) | 2000-03-31 | 2003-04-09 | Daiichi Seiyaku Co | Un derivado del acido quinolonacarboxilico, las composiciones antibacterianas que lo contienen y el uso de dicho derivado para la elaboracion de drogaspara el tratamiento de enfermedades infecciosas |
JP5027975B2 (ja) | 2000-04-24 | 2012-09-19 | 第一三共株式会社 | 安定化液状製剤 |
JP3573287B2 (ja) | 2000-08-08 | 2004-10-06 | 第一製薬株式会社 | 高吸収性固形製剤 |
JPWO2003097634A1 (ja) * | 2002-05-17 | 2005-09-15 | 第一製薬株式会社 | キノロンカルボン酸誘導体の製造方法 |
ES2354214T3 (es) * | 2003-01-07 | 2011-03-11 | Daiichi Sankyo Company, Limited | Proceso de deshalogenación reductora. |
US7085154B2 (en) * | 2003-06-03 | 2006-08-01 | Samsung Electronics Co., Ltd. | Device and method for pulse width control in a phase change memory device |
EP1757598A4 (en) * | 2004-05-13 | 2010-07-21 | Daiichi Seiyaku Co | SUBSTITUTED PYRROLIDINE DERIVATIVE |
JP5063032B2 (ja) * | 2005-05-19 | 2012-10-31 | 第一三共株式会社 | トリ−、テトラ−置換−3−アミノピロリジン誘導体 |
US7563805B2 (en) | 2005-05-19 | 2009-07-21 | Daiichi Pharmaceutical Co., Ltd. | Tri-, tetra-substituted-3-aminopyrrolidine derivative |
EP1882685A4 (en) | 2005-05-20 | 2010-10-27 | Daiichi Sankyo Co Ltd | METHOD FOR PRODUCING AN ASYMMETRIC TETRASUBSTITUTED CARBON CONTAINING COMPOUND |
US7977346B2 (en) | 2006-01-17 | 2011-07-12 | Guoqing Paul Chen | Spiro compounds and methods of use |
TWI386401B (zh) * | 2006-03-27 | 2013-02-21 | Daiichi Seiyaku Co | 醫藥用水合物 |
ES2428344T3 (es) | 2007-01-05 | 2013-11-07 | Daiichi Sankyo Company, Limited | Derivado de aminopirrolidina sustituido fusionado |
JP5414395B2 (ja) | 2008-07-11 | 2014-02-12 | 住友化学株式会社 | (1s,2r)−2−クロロ−2−フルオロシクロプロパンカルボン酸の製造方法 |
FR2961207B1 (fr) * | 2010-06-09 | 2013-01-18 | Oreal | Utilisation d'un derive de 4- carboxy 2-pyrrolidinone comme solvant dans les compositions cosmetiques ; compositions cosmetiques les contenant ; nouveaux composes |
CN103467448B (zh) * | 2013-09-18 | 2015-04-15 | 浙江司太立制药股份有限公司 | 7-(3-氨基-4-烷氧亚胺基-1-哌啶基)-1-[(1r,2s)-2-氟环丙基]喹诺酮羧酸类化合物及其制备方法 |
EP2957561A1 (en) * | 2014-06-18 | 2015-12-23 | Université Paris 6 Pierre et Marie Curie UPMC | Novel fluoroquinolones and use thereof to treat bacterial infections |
CN105330590B (zh) * | 2015-10-15 | 2018-09-25 | 广州市朗启医药科技有限责任公司 | 西他沙星五元环侧链中间体的制备方法 |
CN109912504B (zh) * | 2019-04-04 | 2020-11-10 | 山东省联合农药工业有限公司 | 一种喹啉羧酸类化合物及其制备方法与用途 |
Family Cites Families (17)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS6212760A (ja) * | 1984-12-14 | 1987-01-21 | Dai Ichi Seiyaku Co Ltd | 1−(2−ハロゲノシクロプロピル)キノリンカルボン酸誘導体 |
AU5427286A (en) * | 1985-03-08 | 1986-09-11 | Kyorin Pharmaceutical Co. Ltd. | 7-(1-pyrrolidinyl)-3-quinolinecarboxylic acid derivatives |
DE3509546A1 (de) * | 1985-03-16 | 1986-09-25 | Bayer Ag, 5090 Leverkusen | 7-amino-1-(subst.cyclopropyl)-1,4-dihydro-4-oxo-3-chinolincarbonsaeuren, verfahren zu ihrer herstellung sowie diese enthaltende antibakterielle mittel |
US4657913A (en) | 1985-04-18 | 1987-04-14 | Warner-Lambert Company | Trifluoro- quinoline -3- carboxylic acids and their use as anti-bacterial agents |
US4668680A (en) * | 1985-12-12 | 1987-05-26 | Warner-Lambert Company | 5-amino-6,8-difluoroquinolones as antibacterial agents |
US4735949A (en) | 1986-02-18 | 1988-04-05 | Warner-Lambert Company | Disubstituted-7-pyrrolidinonaphthyridine antibacterial agents |
DE3705621C2 (de) * | 1986-02-25 | 1997-01-09 | Otsuka Pharma Co Ltd | Heterocyclisch substituierte Chinoloncarbonsäurederivate |
DE3702393A1 (de) * | 1987-01-28 | 1988-08-11 | Bayer Ag | 8-cyano-1-cyclopropyl-1,4-dihydro-4-oxo- 3-chinolincarbonsaeuren, verfahren zu ihrer herstellung und diese enthaltende antibakterielle mittel |
US5290934A (en) * | 1987-04-16 | 1994-03-01 | Otsuka Pharmaceutical Company, Limited | Benzoheterocyclic compounds |
US4851418A (en) * | 1987-08-21 | 1989-07-25 | Warner-Lambert Company | Naphthyridine antibacterial agents containing an α-amino acid in the side chain of the 7-substituent |
IL90062A (en) * | 1988-04-27 | 1994-10-07 | Daiichi Seiyaku Co | History of pyridonecarboxylic acid, their preparation and pharmaceutical preparations containing them |
AU618823B2 (en) * | 1988-07-20 | 1992-01-09 | Sankyo Company Limited | 4-oxoquinoline-3-carboxylic acid derivatives, their preparation and their use |
US5286723A (en) | 1988-08-31 | 1994-02-15 | Daiichi Seiyaku Co., Ltd. | Spiro compound |
FI901201A0 (fi) * | 1989-03-13 | 1990-03-09 | Bristol Myers Squibb Co | Antibakteriella 5-substituerade 1,4-dihydro-4-oxonaftyridin-3-karboxylatderivat och deras framstaellning. |
DE3910663A1 (de) * | 1989-04-03 | 1990-10-04 | Bayer Ag | 5-alkylchinoloncarbonsaeuren |
AR027761A1 (es) | 2000-03-31 | 2003-04-09 | Daiichi Seiyaku Co | Un derivado del acido quinolonacarboxilico, las composiciones antibacterianas que lo contienen y el uso de dicho derivado para la elaboracion de drogaspara el tratamiento de enfermedades infecciosas |
EP1757598A4 (en) * | 2004-05-13 | 2010-07-21 | Daiichi Seiyaku Co | SUBSTITUTED PYRROLIDINE DERIVATIVE |
-
1989
- 1989-04-24 IL IL9006289A patent/IL90062A/en unknown
- 1989-04-24 MY MYPI89000521A patent/MY105136A/en unknown
- 1989-04-25 NO NO891698A patent/NO175939C/no not_active IP Right Cessation
- 1989-04-26 FI FI891980A patent/FI96947C/fi not_active IP Right Cessation
- 1989-04-26 NZ NZ228893A patent/NZ228893A/xx unknown
- 1989-04-26 AU AU33702/89A patent/AU625414B2/en not_active Ceased
- 1989-04-26 JP JP1106762A patent/JP2714597B2/ja not_active Expired - Lifetime
- 1989-04-26 ES ES89107550T patent/ES2135372T3/es not_active Expired - Lifetime
- 1989-04-26 PT PT90377A patent/PT90377B/pt not_active IP Right Cessation
- 1989-04-26 EP EP89107550A patent/EP0341493B1/en not_active Expired - Lifetime
- 1989-04-26 SG SG1996006401A patent/SG48036A1/en unknown
- 1989-04-26 DE DE68929030T patent/DE68929030T2/de not_active Expired - Lifetime
- 1989-04-26 YU YU87589A patent/YU48432B/sh unknown
- 1989-04-26 AT AT89107550T patent/ATE182145T1/de not_active IP Right Cessation
- 1989-04-26 CA CA000597865A patent/CA1340801C/en not_active Expired - Fee Related
- 1989-04-26 UA UA5001894A patent/UA29378C2/ru unknown
- 1989-04-27 DK DK205789A patent/DK175467B1/da not_active IP Right Cessation
- 1989-04-27 CN CN89103911A patent/CN1033751C/zh not_active Expired - Lifetime
- 1989-04-27 KR KR1019890005539A patent/KR0184614B1/ko not_active IP Right Cessation
-
1991
- 1991-10-29 RU SU915001894A patent/RU2075475C1/ru not_active IP Right Cessation
-
1992
- 1992-12-30 LV LVP-92-696A patent/LV10092B/en unknown
-
1993
- 1993-10-28 US US08/142,105 patent/US5587386A/en not_active Ceased
-
1994
- 1994-02-28 BG BG098620A patent/BG61122B2/bg unknown
-
1995
- 1995-04-13 JP JP7088282A patent/JP2903292B2/ja not_active Expired - Lifetime
- 1995-06-07 US US08/477,886 patent/US5767127A/en not_active Expired - Lifetime
- 1995-06-22 HU HU95P/P00371P patent/HU211136A9/hu unknown
-
1997
- 1997-07-31 JP JP9205599A patent/JP2917010B2/ja not_active Expired - Fee Related
-
1998
- 1998-01-21 HK HK98100553A patent/HK1002108A1/xx not_active IP Right Cessation
- 1998-04-06 US US09/055,127 patent/US6031102A/en not_active Expired - Fee Related
- 1998-08-20 JP JP10233763A patent/JPH11124367A/ja active Pending
- 1998-08-20 JP JP10233764A patent/JPH11124380A/ja active Pending
-
1999
- 1999-09-29 GR GR990402459T patent/GR3031365T3/el unknown
-
2004
- 2004-06-03 US US10/859,587 patent/USRE41149E1/en not_active Expired - Lifetime
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Legal Events
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