IL165930A0 - Process for the preparation of crystalline nano-particle dispersions - Google Patents

Process for the preparation of crystalline nano-particle dispersions

Info

Publication number
IL165930A0
IL165930A0 IL16593004A IL16593004A IL165930A0 IL 165930 A0 IL165930 A0 IL 165930A0 IL 16593004 A IL16593004 A IL 16593004A IL 16593004 A IL16593004 A IL 16593004A IL 165930 A0 IL165930 A0 IL 165930A0
Authority
IL
Israel
Prior art keywords
preparation
dispersion
water
particle dispersions
insoluble substance
Prior art date
Application number
IL16593004A
Other languages
English (en)
Original Assignee
Astrazeneca Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Astrazeneca Ab filed Critical Astrazeneca Ab
Publication of IL165930A0 publication Critical patent/IL165930A0/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
    • A61K9/145—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
    • A61K9/146—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic macromolecular compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/51—Nanocapsules; Nanoparticles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/51—Nanocapsules; Nanoparticles
    • A61K9/5107—Excipients; Inactive ingredients
    • A61K9/513—Organic macromolecular compounds; Dendrimers
    • A61K9/5138—Organic macromolecular compounds; Dendrimers obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B82—NANOTECHNOLOGY
    • B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
    • B82Y40/00—Manufacture or treatment of nanostructures
IL16593004A 2002-07-18 2004-12-22 Process for the preparation of crystalline nano-particle dispersions IL165930A0 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB0216700.5A GB0216700D0 (en) 2002-07-18 2002-07-18 Process
PCT/GB2003/003044 WO2004009057A1 (en) 2002-07-18 2003-07-14 Process for the preparation of crystalline nano-particle dispersions

Publications (1)

Publication Number Publication Date
IL165930A0 true IL165930A0 (en) 2006-01-15

Family

ID=9940704

Family Applications (1)

Application Number Title Priority Date Filing Date
IL16593004A IL165930A0 (en) 2002-07-18 2004-12-22 Process for the preparation of crystalline nano-particle dispersions

Country Status (18)

Country Link
US (1) US7780989B2 (xx)
EP (1) EP1524964B1 (xx)
JP (1) JP2006504511A (xx)
KR (1) KR101061309B1 (xx)
CN (1) CN100594885C (xx)
AT (1) ATE489939T1 (xx)
BR (1) BR0312631A (xx)
CA (1) CA2492709C (xx)
DE (1) DE60335189D1 (xx)
ES (1) ES2355137T3 (xx)
GB (1) GB0216700D0 (xx)
HK (1) HK1075199A1 (xx)
IL (1) IL165930A0 (xx)
MX (1) MXPA05000595A (xx)
NO (1) NO20050860L (xx)
NZ (1) NZ537654A (xx)
WO (1) WO2004009057A1 (xx)
ZA (1) ZA200410343B (xx)

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GB0230087D0 (en) * 2002-12-24 2003-01-29 Astrazeneca Ab Therapeutic agents
GB0302671D0 (en) * 2003-02-06 2003-03-12 Astrazeneca Ab Pharmaceutical formulations
GB0302672D0 (en) * 2003-02-06 2003-03-12 Astrazeneca Ab Pharmaceutical formulations
GB0302673D0 (en) * 2003-02-06 2003-03-12 Astrazeneca Ab Pharmaceutical formulations
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GB0314057D0 (en) * 2003-06-18 2003-07-23 Astrazeneca Ab Therapeutic agents
US20060135523A1 (en) * 2003-06-18 2006-06-22 Astrazeneca Ab 2-substituted 5,6-diaryl-pyrazine derivatives as cb1 modulator
GB0314261D0 (en) * 2003-06-19 2003-07-23 Astrazeneca Ab Therapeutic agents
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CN102048702B (zh) * 2010-12-03 2012-05-23 山东大学 一种联苯双酯纳米结晶制剂及其制备方法
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JP2014532655A (ja) * 2011-10-31 2014-12-08 メルク・シャープ・アンド・ドーム・コーポレーションＭｅｒｃｋ Ｓｈａｒｐ ＆ Ｄｏｈｍｅ Ｃｏｒｐ． ナノ懸濁過程
CN102846554B (zh) * 2012-09-28 2014-11-26 山东大学 一种h2纳米结晶制剂及其制备方法
KR102045732B1 (ko) * 2012-12-28 2019-11-18 엘지디스플레이 주식회사 온도감응형 계면활성제를 이용한 수용성 나노입자의 제조방법
CN103145594B (zh) * 2013-03-26 2014-12-17 四川农业大学 一种制备氟苯尼考微晶体的方法
JPWO2015137289A1 (ja) * 2014-03-10 2017-04-06 国立大学法人 東京大学 水分散性非晶質粒子及びその調製方法
CN107001810A (zh) * 2014-12-15 2017-08-01 M技术株式会社 有机物微粒的制造方法及有机物微粒的改性方法
CN107541209B (zh) * 2016-06-28 2020-09-01 苏州大学 一种将油相纳米粒子转移至水相的方法
CN109020807B (zh) * 2017-06-09 2022-06-24 鲁南制药集团股份有限公司 一种肉豆蔻酸钠晶型及其制备方法
CN107595772B (zh) * 2017-09-26 2020-09-18 山东省药学科学院 一种他克莫司纳米混悬滴眼液的制备方法
CN108383887A (zh) * 2018-03-14 2018-08-10 广东润华药业有限公司 一种替米考星纳米结晶的制备方法
CN109260159B (zh) * 2018-11-29 2021-07-23 沈阳药科大学 一种含有艾地苯醌的药物组合物及其制备方法
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Also Published As

Publication number Publication date
EP1524964A1 (en) 2005-04-27
DE60335189D1 (de) 2011-01-13
KR101061309B1 (ko) 2011-08-31
ZA200410343B (en) 2005-10-17
US7780989B2 (en) 2010-08-24
WO2004009057A1 (en) 2004-01-29
KR20050023432A (ko) 2005-03-09
NO20050860L (no) 2005-04-18
JP2006504511A (ja) 2006-02-09
ATE489939T1 (de) 2010-12-15
GB0216700D0 (en) 2002-08-28
CN100594885C (zh) 2010-03-24
BR0312631A (pt) 2005-04-19
HK1075199A1 (en) 2005-12-09
CA2492709A1 (en) 2004-01-29
AU2003244871A1 (en) 2004-02-09
CN1668280A (zh) 2005-09-14
ES2355137T3 (es) 2011-03-23
EP1524964B1 (en) 2010-12-01
CA2492709C (en) 2012-01-24
NZ537654A (en) 2006-08-31
US20050202092A1 (en) 2005-09-15
MXPA05000595A (es) 2005-04-19

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