IL157470A0 - Isoxazoline derivatives as anti-depressants - Google Patents

Isoxazoline derivatives as anti-depressants

Info

Publication number
IL157470A0
IL157470A0 IL15747002A IL15747002A IL157470A0 IL 157470 A0 IL157470 A0 IL 157470A0 IL 15747002 A IL15747002 A IL 15747002A IL 15747002 A IL15747002 A IL 15747002A IL 157470 A0 IL157470 A0 IL 157470A0
Authority
IL
Israel
Prior art keywords
depressants
isoxazoline derivatives
isoxazoline
derivatives
Prior art date
Application number
IL15747002A
Other languages
English (en)
Original Assignee
Janssen Pharmaceutica N V Jans
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Janssen Pharmaceutica N V Jans filed Critical Janssen Pharmaceutica N V Jans
Publication of IL157470A0 publication Critical patent/IL157470A0/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D498/00Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D498/02Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D498/04Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/18Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/22Anxiolytics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/24Antidepressants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/04Anorexiants; Antiobesity agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D261/00Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings
    • C07D261/20Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings condensed with carbocyclic rings or ring systems

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Epidemiology (AREA)
  • Psychiatry (AREA)
  • Child & Adolescent Psychology (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Pain & Pain Management (AREA)
  • Diabetes (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
IL15747002A 2001-02-21 2002-02-13 Isoxazoline derivatives as anti-depressants IL157470A0 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP01200611 2001-02-21
EP01201264 2001-04-05
PCT/EP2002/001567 WO2002066484A1 (en) 2001-02-21 2002-02-13 Isoxazoline derivatives as anti-depressants

Publications (1)

Publication Number Publication Date
IL157470A0 true IL157470A0 (en) 2004-03-28

Family

ID=26076836

Family Applications (2)

Application Number Title Priority Date Filing Date
IL15747002A IL157470A0 (en) 2001-02-21 2002-02-13 Isoxazoline derivatives as anti-depressants
IL157470A IL157470A (en) 2001-02-21 2003-08-19 History of isoxazoline used as antidepressants

Family Applications After (1)

Application Number Title Priority Date Filing Date
IL157470A IL157470A (en) 2001-02-21 2003-08-19 History of isoxazoline used as antidepressants

Country Status (33)

Country Link
US (1) US7169786B2 (de)
EP (1) EP1368358B1 (de)
JP (1) JP3953424B2 (de)
KR (1) KR100848898B1 (de)
CN (1) CN100400540C (de)
AR (1) AR035685A1 (de)
AT (1) ATE337322T1 (de)
AU (1) AU2002244717B2 (de)
BG (1) BG107984A (de)
BR (1) BR0207433A (de)
CA (1) CA2437505C (de)
CY (1) CY1106448T1 (de)
CZ (1) CZ20032515A3 (de)
DE (1) DE60214138T2 (de)
DK (1) DK1368358T3 (de)
EA (1) EA006747B1 (de)
EE (1) EE200300398A (de)
EG (1) EG23929A (de)
ES (1) ES2271230T3 (de)
HK (1) HK1065537A1 (de)
HR (1) HRP20030647A2 (de)
HU (1) HUP0303270A3 (de)
IL (2) IL157470A0 (de)
MX (1) MXPA03007432A (de)
MY (1) MY137836A (de)
NO (1) NO20033700L (de)
NZ (1) NZ526741A (de)
PL (1) PL208593B1 (de)
PT (1) PT1368358E (de)
SI (1) SI1368358T1 (de)
SK (1) SK11612003A3 (de)
TW (1) TWI257392B (de)
WO (1) WO2002066484A1 (de)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0203299D0 (en) * 2002-02-12 2002-03-27 Glaxo Group Ltd Novel compounds
DE60316134T2 (de) * 2002-04-02 2008-05-29 Janssen Pharmaceutica N.V. Substituierte aminoisoxazolinderivate und ihre verwendung als antidepressiva
AR040967A1 (es) * 2002-08-12 2005-04-27 Janssen Pharmaceutica Nv Derivados de isoxazolina triciclicos c- sustituidos y su uso como anti- depresivos
CN100522972C (zh) * 2002-08-15 2009-08-05 詹森药业有限公司 稠合杂环异噁唑啉衍生物和它们作为抗抑郁剂的用途
ATE387455T1 (de) * 2002-08-21 2008-03-15 Janssen Pharmaceutica Nv C6- und c9-substituierte chromeno(4,3- c)isoxazoline und ihre verwendung als anti- depressiva
KR20050114641A (ko) 2003-03-07 2005-12-06 아스텔라스세이야쿠 가부시키가이샤 2,6-이치환된 스티릴을 갖는 질소 함유 헤테로환 유도체
EP1905774B1 (de) * 2003-09-17 2013-02-20 Janssen Pharmaceutica N.V. Kondensierte heterocyclische Verbindungen als Modulatoren des Serotoninrezeptors
ES2319539T3 (es) * 2003-09-17 2009-05-08 Janssen Pharmaceutica Nv Compuestos heterociclicos condensados como moduladores del receptor de serotonina.
US7635696B2 (en) 2004-11-26 2009-12-22 Janssen Pharmaceutica N.V. Isoxazoline-indole derivatives with an improved antipsychotic and anxiolytic activity
MY147757A (en) * 2007-03-09 2013-01-15 Sanofi Aventis Substituted dihydro and tetrahydro oxazolopyrimidinones, preparation and use thereof
CN101686682A (zh) * 2007-06-08 2010-03-31 海利空医疗公司 治疗用吡唑并喹啉脲衍生物
EP2236511A4 (de) 2007-12-21 2011-04-13 Alla Chem Llc Liganden von alpha-adrenoceptoren und von dopamin-, histamin-, imidazolin- und serotoninrezeptoren und anwendung davon
AR078171A1 (es) 2009-09-15 2011-10-19 Sanofi Aventis Dihidrobenzocicloalquiloximetil-oxazolopirimidinonas sustituidas, preparacion y uso de las mismas

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2055011T3 (es) * 1988-09-19 1994-08-16 Akzo Nv Un procedimiento para la preparacion de derivados de tetrahidronaftaleno e indano.
US5880121A (en) * 1996-01-05 1999-03-09 Hoechst Marion Roussel Inc. 4,5-dihydronaphth (1,2-c) isoxazoles and derivatives thereof
NZ329954A (en) * 1996-04-12 1999-07-29 Janssen Pharmaceutica Nv Isoxazolidine tetracyclic and tricyclic ring system derivatives and medicaments
HUP9602763A3 (en) * 1996-10-09 1999-05-28 Egyt Gyogyszervegyeszeti Gyar 3-phenyl isoxazole derivatives, process for producing them and pharmaceutical compositions containing the same
EP1119568B1 (de) * 1998-10-09 2004-02-18 Janssen Pharmaceutica N.V. 4,5-dehydroisoxazole derivate und ihre pharmazeutische verwendung

Also Published As

Publication number Publication date
ES2271230T3 (es) 2007-04-16
DE60214138D1 (de) 2006-10-05
PT1368358E (pt) 2007-01-31
CZ20032515A3 (cs) 2003-12-17
JP2004518748A (ja) 2004-06-24
JP3953424B2 (ja) 2007-08-08
KR100848898B1 (ko) 2008-07-29
BG107984A (bg) 2004-09-30
SI1368358T1 (sl) 2007-02-28
HRP20030647A2 (en) 2005-06-30
MY137836A (en) 2009-03-31
WO2002066484A1 (en) 2002-08-29
NZ526741A (en) 2004-04-30
BR0207433A (pt) 2004-06-01
CA2437505C (en) 2010-02-09
ATE337322T1 (de) 2006-09-15
NO20033700D0 (no) 2003-08-20
KR20030076590A (ko) 2003-09-26
HUP0303270A2 (hu) 2004-01-28
US7169786B2 (en) 2007-01-30
DK1368358T3 (da) 2007-01-02
HK1065537A1 (en) 2005-02-25
PL363264A1 (en) 2004-11-15
CN100400540C (zh) 2008-07-09
CY1106448T1 (el) 2011-10-12
EA200300915A1 (ru) 2004-06-24
NO20033700L (no) 2003-10-21
SK11612003A3 (sk) 2004-04-06
CN1492871A (zh) 2004-04-28
AU2002244717B2 (en) 2007-07-19
DE60214138T2 (de) 2007-03-29
EA006747B1 (ru) 2006-04-28
TWI257392B (en) 2006-07-01
AR035685A1 (es) 2004-06-23
CA2437505A1 (en) 2002-08-29
HUP0303270A3 (en) 2007-03-28
EP1368358B1 (de) 2006-08-23
EG23929A (en) 2008-01-14
MXPA03007432A (es) 2003-11-18
EE200300398A (et) 2003-12-15
PL208593B1 (pl) 2011-05-31
EP1368358A1 (de) 2003-12-10
US20040122037A1 (en) 2004-06-24
IL157470A (en) 2008-07-08

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