ATE337322T1 - Isoxazolin-derivate als antidepressiva - Google Patents

Isoxazolin-derivate als antidepressiva

Info

Publication number
ATE337322T1
ATE337322T1 AT02712909T AT02712909T ATE337322T1 AT E337322 T1 ATE337322 T1 AT E337322T1 AT 02712909 T AT02712909 T AT 02712909T AT 02712909 T AT02712909 T AT 02712909T AT E337322 T1 ATE337322 T1 AT E337322T1
Authority
AT
Austria
Prior art keywords
antidepressants
isoxazoline derivatives
isoxazoline
derivatives
Prior art date
Application number
AT02712909T
Other languages
English (en)
Inventor
J I Andres-Gil
F J Fernandez-Gadea
M J Alcazar-Vaca
J M Cid-Nunez
J Pastor-Fernandez
A A H P Megens
G I C M Heylen
X J M Langlois
M H M Bakker
T H W Steckler
Original Assignee
Janssen Pharmaceutica Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Janssen Pharmaceutica Nv filed Critical Janssen Pharmaceutica Nv
Application granted granted Critical
Publication of ATE337322T1 publication Critical patent/ATE337322T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D498/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D498/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/22—Anxiolytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D261/00—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings
    • C07D261/20—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings condensed with carbocyclic rings or ring systems

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Epidemiology (AREA)
  • Psychiatry (AREA)
  • Child & Adolescent Psychology (AREA)
  • Pain & Pain Management (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Diabetes (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
AT02712909T 2001-02-21 2002-02-13 Isoxazolin-derivate als antidepressiva ATE337322T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP01200611 2001-02-21
EP01201264 2001-04-05

Publications (1)

Publication Number Publication Date
ATE337322T1 true ATE337322T1 (de) 2006-09-15

Family

ID=26076836

Family Applications (1)

Application Number Title Priority Date Filing Date
AT02712909T ATE337322T1 (de) 2001-02-21 2002-02-13 Isoxazolin-derivate als antidepressiva

Country Status (32)

Country Link
US (1) US7169786B2 (de)
EP (1) EP1368358B1 (de)
JP (1) JP3953424B2 (de)
KR (1) KR100848898B1 (de)
CN (1) CN100400540C (de)
AR (1) AR035685A1 (de)
AT (1) ATE337322T1 (de)
AU (1) AU2002244717B2 (de)
BG (1) BG107984A (de)
BR (1) BR0207433A (de)
CA (1) CA2437505C (de)
CY (1) CY1106448T1 (de)
CZ (1) CZ20032515A3 (de)
DE (1) DE60214138T2 (de)
DK (1) DK1368358T3 (de)
EA (1) EA006747B1 (de)
EE (1) EE200300398A (de)
EG (1) EG23929A (de)
ES (1) ES2271230T3 (de)
HR (1) HRP20030647A2 (de)
HU (1) HUP0303270A3 (de)
IL (2) IL157470A0 (de)
MX (1) MXPA03007432A (de)
MY (1) MY137836A (de)
NO (1) NO20033700L (de)
NZ (1) NZ526741A (de)
PL (1) PL208593B1 (de)
PT (1) PT1368358E (de)
SI (1) SI1368358T1 (de)
SK (1) SK11612003A3 (de)
TW (1) TWI257392B (de)
WO (1) WO2002066484A1 (de)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0203299D0 (en) * 2002-02-12 2002-03-27 Glaxo Group Ltd Novel compounds
DE60316134T2 (de) * 2002-04-02 2008-05-29 Janssen Pharmaceutica N.V. Substituierte aminoisoxazolinderivate und ihre verwendung als antidepressiva
AR040967A1 (es) * 2002-08-12 2005-04-27 Janssen Pharmaceutica Nv Derivados de isoxazolina triciclicos c- sustituidos y su uso como anti- depresivos
CN100522972C (zh) * 2002-08-15 2009-08-05 詹森药业有限公司 稠合杂环异噁唑啉衍生物和它们作为抗抑郁剂的用途
US7462717B2 (en) 2002-08-21 2008-12-09 Janssen Pharmaceutica N.V. C6-and C9-substituted chromeno[4,3-c]isoxazoline derivatives and their use as anti-depressants
ZA200507486B (en) 2003-03-07 2007-03-28 Astellas Pharma Inc Nitrogenous heterocyclic derivative having 2,6-disubstituted styryl
EP1944306A1 (de) * 2003-09-17 2008-07-16 Janssen Pharmaceutica, N.V. Fusionierte heterocyclische Verbindungen
DE602004019118D1 (de) 2003-09-17 2009-03-05 Janssen Pharmaceutica Nv Kondensierte heterocyclische verbindungen als modulatoren des serotoninrezeptors
US7635696B2 (en) 2004-11-26 2009-12-22 Janssen Pharmaceutica N.V. Isoxazoline-indole derivatives with an improved antipsychotic and anxiolytic activity
MY147757A (en) 2007-03-09 2013-01-15 Sanofi Aventis Substituted dihydro and tetrahydro oxazolopyrimidinones, preparation and use thereof
US7863266B2 (en) * 2007-06-08 2011-01-04 Helicon Therapeutics, Inc. Therapeutic pyrazoloquinoline urea derivatives
JP2011507835A (ja) 2007-12-21 2011-03-10 アンドレイ・アレクサンドロビッチ・イワシェンコ α−アドレナリン受容体、ドーパミン、ヒスタミン、イミダゾリン及びセロトニン受容体のリガンド並びにその使用
AR078171A1 (es) 2009-09-15 2011-10-19 Sanofi Aventis Dihidrobenzocicloalquiloximetil-oxazolopirimidinonas sustituidas, preparacion y uso de las mismas

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE68906340T2 (de) 1988-09-19 1993-08-12 Akzo Nv Tetrahydronaphthalin und indan-derivate.
US5880121A (en) * 1996-01-05 1999-03-09 Hoechst Marion Roussel Inc. 4,5-dihydronaphth (1,2-c) isoxazoles and derivatives thereof
PL186541B1 (pl) * 1996-04-12 2004-01-30 Janssen Pharmaceutica Nv Nowy związek, pochodna izoksazolidyny, kompozycjafarmaceutyczna, zastosowanie pochodnej izoksazolidyny i sposób wytwarzania pochodnej izoksazolidyny
HUP9602763A3 (en) * 1996-10-09 1999-05-28 Egyt Gyogyszervegyeszeti Gyar 3-phenyl isoxazole derivatives, process for producing them and pharmaceutical compositions containing the same
CA2346396C (en) * 1998-10-09 2009-04-28 Janssen Pharmaceutica N.V. 4,5-dihydro-isoxazole derivatives and their pharmaceutical use

Also Published As

Publication number Publication date
DE60214138D1 (de) 2006-10-05
CA2437505C (en) 2010-02-09
PL208593B1 (pl) 2011-05-31
HUP0303270A3 (en) 2007-03-28
HK1065537A1 (zh) 2005-02-25
DK1368358T3 (da) 2007-01-02
CY1106448T1 (el) 2011-10-12
EE200300398A (et) 2003-12-15
KR100848898B1 (ko) 2008-07-29
IL157470A0 (en) 2004-03-28
PL363264A1 (en) 2004-11-15
EA006747B1 (ru) 2006-04-28
JP3953424B2 (ja) 2007-08-08
TWI257392B (en) 2006-07-01
AR035685A1 (es) 2004-06-23
CA2437505A1 (en) 2002-08-29
CN1492871A (zh) 2004-04-28
EG23929A (en) 2008-01-14
EP1368358A1 (de) 2003-12-10
US7169786B2 (en) 2007-01-30
AU2002244717B2 (en) 2007-07-19
US20040122037A1 (en) 2004-06-24
ES2271230T3 (es) 2007-04-16
PT1368358E (pt) 2007-01-31
NO20033700D0 (no) 2003-08-20
KR20030076590A (ko) 2003-09-26
JP2004518748A (ja) 2004-06-24
MY137836A (en) 2009-03-31
IL157470A (en) 2008-07-08
BR0207433A (pt) 2004-06-01
HUP0303270A2 (hu) 2004-01-28
DE60214138T2 (de) 2007-03-29
CZ20032515A3 (cs) 2003-12-17
EP1368358B1 (de) 2006-08-23
NZ526741A (en) 2004-04-30
HRP20030647A2 (en) 2005-06-30
SK11612003A3 (sk) 2004-04-06
MXPA03007432A (es) 2003-11-18
CN100400540C (zh) 2008-07-09
NO20033700L (no) 2003-10-21
SI1368358T1 (sl) 2007-02-28
WO2002066484A1 (en) 2002-08-29
BG107984A (bg) 2004-09-30
EA200300915A1 (ru) 2004-06-24

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