ATE337322T1 - Isoxazolin-derivate als antidepressiva - Google Patents

Isoxazolin-derivate als antidepressiva

Info

Publication number
ATE337322T1
ATE337322T1 AT02712909T AT02712909T ATE337322T1 AT E337322 T1 ATE337322 T1 AT E337322T1 AT 02712909 T AT02712909 T AT 02712909T AT 02712909 T AT02712909 T AT 02712909T AT E337322 T1 ATE337322 T1 AT E337322T1
Authority
AT
Austria
Prior art keywords
antidepressants
isoxazoline derivatives
isoxazoline
derivatives
Prior art date
Application number
AT02712909T
Other languages
English (en)
Inventor
J I Andres-Gil
F J Fernandez-Gadea
M J Alcazar-Vaca
J M Cid-Nunez
J Pastor-Fernandez
A A H P Megens
G I C M Heylen
X J M Langlois
M H M Bakker
T H W Steckler
Original Assignee
Janssen Pharmaceutica Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Janssen Pharmaceutica Nv filed Critical Janssen Pharmaceutica Nv
Application granted granted Critical
Publication of ATE337322T1 publication Critical patent/ATE337322T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D498/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D498/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/22—Anxiolytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D261/00—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings
    • C07D261/20—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings condensed with carbocyclic rings or ring systems

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Epidemiology (AREA)
  • Psychiatry (AREA)
  • Child & Adolescent Psychology (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Diabetes (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
AT02712909T 2001-02-21 2002-02-13 Isoxazolin-derivate als antidepressiva ATE337322T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP01200611 2001-02-21
EP01201264 2001-04-05

Publications (1)

Publication Number Publication Date
ATE337322T1 true ATE337322T1 (de) 2006-09-15

Family

ID=26076836

Family Applications (1)

Application Number Title Priority Date Filing Date
AT02712909T ATE337322T1 (de) 2001-02-21 2002-02-13 Isoxazolin-derivate als antidepressiva

Country Status (33)

Country Link
US (1) US7169786B2 (de)
EP (1) EP1368358B1 (de)
JP (1) JP3953424B2 (de)
KR (1) KR100848898B1 (de)
CN (1) CN100400540C (de)
AR (1) AR035685A1 (de)
AT (1) ATE337322T1 (de)
AU (1) AU2002244717B2 (de)
BG (1) BG107984A (de)
BR (1) BR0207433A (de)
CA (1) CA2437505C (de)
CY (1) CY1106448T1 (de)
CZ (1) CZ20032515A3 (de)
DE (1) DE60214138T2 (de)
DK (1) DK1368358T3 (de)
EA (1) EA006747B1 (de)
EE (1) EE200300398A (de)
EG (1) EG23929A (de)
ES (1) ES2271230T3 (de)
HK (1) HK1065537A1 (de)
HR (1) HRP20030647A2 (de)
HU (1) HUP0303270A3 (de)
IL (2) IL157470A0 (de)
MX (1) MXPA03007432A (de)
MY (1) MY137836A (de)
NO (1) NO20033700L (de)
NZ (1) NZ526741A (de)
PL (1) PL208593B1 (de)
PT (1) PT1368358E (de)
SI (1) SI1368358T1 (de)
SK (1) SK11612003A3 (de)
TW (1) TWI257392B (de)
WO (1) WO2002066484A1 (de)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0203299D0 (en) * 2002-02-12 2002-03-27 Glaxo Group Ltd Novel compounds
WO2003082878A1 (en) * 2002-04-02 2003-10-09 Janssen Pharmaceutica N.V. Substituted amino isoxazoline derivatives and their use as anti-depressants.
TW200409777A (en) * 2002-08-12 2004-06-16 Janssen Pharmaceutica Nv C-substituted tricyclic isoxazoline derivatives and their use as anti-depressants
EP1554286B1 (de) * 2002-08-15 2010-01-27 Janssen Pharmaceutica N.V. Kondensierte heterocyclische isoxazolinderivate und deren verwendung als antidepressiva
EP1532155B1 (de) * 2002-08-21 2008-02-27 Janssen Pharmaceutica N.V. C6- UND C9-SUBSTITUIERTE CHROMENO[4,3-c]ISOXAZOLINE UND IHRE VERWENDUNG ALS ANTI-DEPRESSIVA
KR20050114641A (ko) 2003-03-07 2005-12-06 아스텔라스세이야쿠 가부시키가이샤 2,6-이치환된 스티릴을 갖는 질소 함유 헤테로환 유도체
ATE420881T1 (de) 2003-09-17 2009-01-15 Janssen Pharmaceutica Nv Kondensierte heterocyclische verbindungen als modulatoren des serotoninrezeptors
EP1905774B1 (de) * 2003-09-17 2013-02-20 Janssen Pharmaceutica N.V. Kondensierte heterocyclische Verbindungen als Modulatoren des Serotoninrezeptors
DE602005016836D1 (de) * 2004-11-26 2009-11-05 Janssen Pharmaceutica Nv Chotischer und anxiolytischer aktivität
MX2009009447A (es) * 2007-03-09 2009-09-14 Sanofi Aventis Dihidro y tetrahidro oxazolopirimidinonas sustituidas, preparacion y uso de las mismas.
US7863266B2 (en) * 2007-06-08 2011-01-04 Helicon Therapeutics, Inc. Therapeutic pyrazoloquinoline urea derivatives
EP2236511A4 (de) 2007-12-21 2011-04-13 Alla Chem Llc Liganden von alpha-adrenoceptoren und von dopamin-, histamin-, imidazolin- und serotoninrezeptoren und anwendung davon
AR078171A1 (es) 2009-09-15 2011-10-19 Sanofi Aventis Dihidrobenzocicloalquiloximetil-oxazolopirimidinonas sustituidas, preparacion y uso de las mismas

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2055011T3 (es) 1988-09-19 1994-08-16 Akzo Nv Un procedimiento para la preparacion de derivados de tetrahidronaftaleno e indano.
US5880121A (en) * 1996-01-05 1999-03-09 Hoechst Marion Roussel Inc. 4,5-dihydronaphth (1,2-c) isoxazoles and derivatives thereof
PT892804E (pt) * 1996-04-12 2003-01-31 Janssen Pharmaceutica Nv Derivados de isoxazolidina
HUP9602763A3 (en) * 1996-10-09 1999-05-28 Egyt Gyogyszervegyeszeti Gyar 3-phenyl isoxazole derivatives, process for producing them and pharmaceutical compositions containing the same
EP1119568B1 (de) * 1998-10-09 2004-02-18 Janssen Pharmaceutica N.V. 4,5-dehydroisoxazole derivate und ihre pharmazeutische verwendung

Also Published As

Publication number Publication date
KR100848898B1 (ko) 2008-07-29
HUP0303270A2 (hu) 2004-01-28
DE60214138D1 (de) 2006-10-05
NO20033700L (no) 2003-10-21
JP3953424B2 (ja) 2007-08-08
EP1368358B1 (de) 2006-08-23
BG107984A (bg) 2004-09-30
HRP20030647A2 (en) 2005-06-30
CN1492871A (zh) 2004-04-28
DE60214138T2 (de) 2007-03-29
EE200300398A (et) 2003-12-15
US20040122037A1 (en) 2004-06-24
EA006747B1 (ru) 2006-04-28
JP2004518748A (ja) 2004-06-24
MY137836A (en) 2009-03-31
EG23929A (en) 2008-01-14
IL157470A0 (en) 2004-03-28
EP1368358A1 (de) 2003-12-10
NO20033700D0 (no) 2003-08-20
PT1368358E (pt) 2007-01-31
WO2002066484A1 (en) 2002-08-29
SI1368358T1 (sl) 2007-02-28
HUP0303270A3 (en) 2007-03-28
CA2437505C (en) 2010-02-09
PL208593B1 (pl) 2011-05-31
AU2002244717B2 (en) 2007-07-19
BR0207433A (pt) 2004-06-01
DK1368358T3 (da) 2007-01-02
TWI257392B (en) 2006-07-01
HK1065537A1 (en) 2005-02-25
SK11612003A3 (sk) 2004-04-06
KR20030076590A (ko) 2003-09-26
NZ526741A (en) 2004-04-30
EA200300915A1 (ru) 2004-06-24
US7169786B2 (en) 2007-01-30
CY1106448T1 (el) 2011-10-12
AR035685A1 (es) 2004-06-23
CA2437505A1 (en) 2002-08-29
IL157470A (en) 2008-07-08
CZ20032515A3 (cs) 2003-12-17
MXPA03007432A (es) 2003-11-18
CN100400540C (zh) 2008-07-09
ES2271230T3 (es) 2007-04-16
PL363264A1 (en) 2004-11-15

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