IL155712A0 - Aminothiazoles and their use as adenosine receptor antagonists - Google Patents
Aminothiazoles and their use as adenosine receptor antagonistsInfo
- Publication number
- IL155712A0 IL155712A0 IL15571201A IL15571201A IL155712A0 IL 155712 A0 IL155712 A0 IL 155712A0 IL 15571201 A IL15571201 A IL 15571201A IL 15571201 A IL15571201 A IL 15571201A IL 155712 A0 IL155712 A0 IL 155712A0
- Authority
- IL
- Israel
- Prior art keywords
- aminothiazoles
- receptor antagonists
- adenosine receptor
- adenosine
- antagonists
- Prior art date
Links
- RAIPHJJURHTUIC-UHFFFAOYSA-N 1,3-thiazol-2-amine Chemical class NC1=NC=CS1 RAIPHJJURHTUIC-UHFFFAOYSA-N 0.000 title 1
- 229940121359 adenosine receptor antagonist Drugs 0.000 title 1
- 239000000296 purinergic P1 receptor antagonist Substances 0.000 title 1
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
- C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
- C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D231/12—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
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- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
-
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- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
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- A—HUMAN NECESSITIES
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- A—HUMAN NECESSITIES
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/56—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
- C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
- C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
Landscapes
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pulmonology (AREA)
- Diabetes (AREA)
- Ophthalmology & Optometry (AREA)
- Dermatology (AREA)
- Neurology (AREA)
- Immunology (AREA)
- Hematology (AREA)
- Neurosurgery (AREA)
- Physical Education & Sports Medicine (AREA)
- Urology & Nephrology (AREA)
- Biomedical Technology (AREA)
- Emergency Medicine (AREA)
- Obesity (AREA)
- Otolaryngology (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Gastroenterology & Hepatology (AREA)
- Toxicology (AREA)
- Endocrinology (AREA)
- Hospice & Palliative Care (AREA)
- Psychiatry (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Vascular Medicine (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GBGB0028383.8A GB0028383D0 (en) | 2000-11-21 | 2000-11-21 | Organic compounds |
PCT/EP2001/013378 WO2002042298A1 (en) | 2000-11-21 | 2001-11-19 | Aminothiazoles and their use as adenosine receptor antagonists |
Publications (1)
Publication Number | Publication Date |
---|---|
IL155712A0 true IL155712A0 (en) | 2003-11-23 |
Family
ID=9903594
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IL15571201A IL155712A0 (en) | 2000-11-21 | 2001-11-19 | Aminothiazoles and their use as adenosine receptor antagonists |
Country Status (26)
Country | Link |
---|---|
US (1) | US7109202B2 (es) |
EP (1) | EP1339711B1 (es) |
JP (1) | JP3973556B2 (es) |
KR (1) | KR20040007412A (es) |
CN (1) | CN1244580C (es) |
AR (1) | AR035371A1 (es) |
AT (1) | ATE300536T1 (es) |
AU (1) | AU2002237221A1 (es) |
BR (1) | BR0115478A (es) |
CA (1) | CA2429442A1 (es) |
CZ (1) | CZ20031393A3 (es) |
DE (1) | DE60112322T2 (es) |
EC (1) | ECSP034611A (es) |
ES (1) | ES2246346T3 (es) |
GB (1) | GB0028383D0 (es) |
HU (1) | HUP0302079A2 (es) |
IL (1) | IL155712A0 (es) |
MX (1) | MXPA03004439A (es) |
NO (1) | NO20032277L (es) |
NZ (1) | NZ525875A (es) |
PE (1) | PE20020580A1 (es) |
PL (1) | PL361842A1 (es) |
RU (1) | RU2003117476A (es) |
SK (1) | SK6032003A3 (es) |
WO (1) | WO2002042298A1 (es) |
ZA (1) | ZA200303721B (es) |
Families Citing this family (121)
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US20020115635A1 (en) * | 2001-02-21 | 2002-08-22 | Pnina Fishman | Modulation of GSK-3beta activity and its different uses |
AU2002349705A1 (en) * | 2001-12-03 | 2003-06-17 | Japan Tobacco Inc. | Azole compound and medicinal use thereof |
CN1319967C (zh) * | 2002-01-18 | 2007-06-06 | 安斯泰来制药有限公司 | 2-酰基氨基噻唑衍生物或其盐 |
TW200519106A (en) | 2003-05-02 | 2005-06-16 | Novartis Ag | Organic compounds |
TW200524887A (en) * | 2003-10-27 | 2005-08-01 | Lundbeck & Co As H | N-thiazol-2-yl-benzamide derivatives |
DK1700856T3 (en) * | 2003-12-26 | 2015-12-14 | Kyowa Hakko Kirin Co Ltd | thiazole |
GB0401336D0 (en) * | 2004-01-21 | 2004-02-25 | Novartis Ag | Organic compounds |
GB0401334D0 (en) | 2004-01-21 | 2004-02-25 | Novartis Ag | Organic compounds |
GB0411056D0 (en) | 2004-05-18 | 2004-06-23 | Novartis Ag | Organic compounds |
PE20060272A1 (es) * | 2004-05-24 | 2006-05-22 | Glaxo Group Ltd | (2r,3r,4s,5r,2'r,3'r,4's,5's)-2,2'-{trans-1,4-ciclohexanodiilbis-[imino(2-{[2-(1-metil-1h-imidazol-4-il)etil]amino}-9h-purin-6,9-diil)]}bis[5-(2-etil-2h-tetrazol-5-il)tetrahidro-3,4-furanodiol] como agonista a2a |
GB0417910D0 (en) * | 2004-08-11 | 2004-09-15 | Novartis Ag | Organic compounds |
US7910613B2 (en) | 2004-09-22 | 2011-03-22 | H. Lundbeck A/S | 2-acylaminothiazole derivatives |
BRPI0515519A (pt) * | 2004-09-22 | 2008-07-29 | H. Lundbeck & Co A/S | composto, e, uso do mesmo |
GT200500281A (es) | 2004-10-22 | 2006-04-24 | Novartis Ag | Compuestos organicos. |
GB0424284D0 (en) | 2004-11-02 | 2004-12-01 | Novartis Ag | Organic compounds |
GB0426164D0 (en) | 2004-11-29 | 2004-12-29 | Novartis Ag | Organic compounds |
GB0507577D0 (en) | 2005-04-14 | 2005-05-18 | Novartis Ag | Organic compounds |
US7674912B2 (en) | 2005-04-25 | 2010-03-09 | H. Lundbeck A/S | Pro-drugs of N-thiazol-2-yl-benzamide derivatives |
CA2607617A1 (en) * | 2005-05-09 | 2006-11-16 | Achillion Pharmaceuticals, Inc. | Thiazole compounds and methods of use |
GB0510390D0 (en) | 2005-05-20 | 2005-06-29 | Novartis Ag | Organic compounds |
EP1893607A4 (en) * | 2005-06-09 | 2010-07-21 | Merck Sharp & Dohme | CHECKPOINT KINASE INHIBITORS |
EP1894930A4 (en) * | 2005-06-23 | 2010-06-23 | Kyowa Hakko Kirin Co Ltd | THIAZOLE DERIVATIVE |
GB0514809D0 (en) | 2005-07-19 | 2005-08-24 | Glaxo Group Ltd | Compounds |
ES2270715B1 (es) | 2005-07-29 | 2008-04-01 | Laboratorios Almirall S.A. | Nuevos derivados de pirazina. |
PL1921077T3 (pl) | 2005-08-02 | 2018-01-31 | Kyowa Hakko Kirin Co Ltd | Środek do zapobiegania i/lub leczenia zaburzenia snu |
GB0516313D0 (en) | 2005-08-08 | 2005-09-14 | Argenta Discovery Ltd | Azole derivatives and their uses |
KR20080036632A (ko) | 2005-08-08 | 2008-04-28 | 아젠터 디스커버리 리미티드 | 바이시클로[2.2.1]헵트-7-일아민 유도체 및 이들의 용도 |
EP1926719B1 (en) * | 2005-09-13 | 2017-05-31 | Janssen Pharmaceutica NV | 2-aniline-4-aryl substituted thiazole derivatives |
ES2274712B1 (es) | 2005-10-06 | 2008-03-01 | Laboratorios Almirall S.A. | Nuevos derivados imidazopiridina. |
PT2532679T (pt) | 2005-10-21 | 2017-07-18 | Novartis Ag | Anticorpos humanos contra il13 e utilizações terapêuticas |
AU2006313491B2 (en) * | 2005-11-08 | 2011-01-06 | Astellas Pharma Inc. | Compositions and methods for treating thrombocytopenia |
GB0526244D0 (en) | 2005-12-22 | 2006-02-01 | Novartis Ag | Organic compounds |
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EP2007393B1 (en) * | 2006-04-07 | 2013-08-21 | Board Of Supervisors Of Louisiana State University And Agricultural And Mechanical College | Thiazole and thiophene analogues, and their use in treating autoimmune diseases and cancers |
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-
2000
- 2000-11-21 GB GBGB0028383.8A patent/GB0028383D0/en not_active Ceased
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2001
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- 2001-11-19 AU AU2002237221A patent/AU2002237221A1/en not_active Abandoned
- 2001-11-19 BR BR0115478-8A patent/BR0115478A/pt not_active Application Discontinuation
- 2001-11-19 ES ES01986395T patent/ES2246346T3/es not_active Expired - Lifetime
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- 2001-11-19 WO PCT/EP2001/013378 patent/WO2002042298A1/en active IP Right Grant
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- 2001-11-19 KR KR10-2003-7006156A patent/KR20040007412A/ko not_active Application Discontinuation
- 2001-11-19 NZ NZ525875A patent/NZ525875A/en unknown
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- 2001-11-19 JP JP2002544432A patent/JP3973556B2/ja not_active Expired - Fee Related
- 2001-11-19 PL PL01361842A patent/PL361842A1/xx not_active Application Discontinuation
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- 2001-11-20 PE PE2001001159A patent/PE20020580A1/es not_active Application Discontinuation
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ES2246346T3 (es) | 2006-02-16 |
CN1476447A (zh) | 2004-02-18 |
WO2002042298A1 (en) | 2002-05-30 |
GB0028383D0 (en) | 2001-01-03 |
CZ20031393A3 (cs) | 2003-08-13 |
ZA200303721B (en) | 2004-05-10 |
DE60112322D1 (de) | 2005-09-01 |
AR035371A1 (es) | 2004-05-12 |
NZ525875A (en) | 2004-11-26 |
EP1339711B1 (en) | 2005-07-27 |
BR0115478A (pt) | 2004-02-17 |
EP1339711A1 (en) | 2003-09-03 |
PL361842A1 (en) | 2004-10-04 |
SK6032003A3 (en) | 2004-01-08 |
NO20032277D0 (no) | 2003-05-20 |
NO20032277L (no) | 2003-07-21 |
KR20040007412A (ko) | 2004-01-24 |
RU2003117476A (ru) | 2005-02-10 |
AU2002237221A1 (en) | 2002-06-03 |
JP3973556B2 (ja) | 2007-09-12 |
MXPA03004439A (es) | 2003-08-19 |
US20040053982A1 (en) | 2004-03-18 |
DE60112322T2 (de) | 2006-05-24 |
ATE300536T1 (de) | 2005-08-15 |
HUP0302079A2 (hu) | 2003-09-29 |
CN1244580C (zh) | 2006-03-08 |
PE20020580A1 (es) | 2002-08-13 |
US7109202B2 (en) | 2006-09-19 |
CA2429442A1 (en) | 2002-05-30 |
JP2004521871A (ja) | 2004-07-22 |
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