BR112015029970A2 - inibidores de cinase - Google Patents

inibidores de cinase

Info

Publication number
BR112015029970A2
BR112015029970A2 BR112015029970A BR112015029970A BR112015029970A2 BR 112015029970 A2 BR112015029970 A2 BR 112015029970A2 BR 112015029970 A BR112015029970 A BR 112015029970A BR 112015029970 A BR112015029970 A BR 112015029970A BR 112015029970 A2 BR112015029970 A2 BR 112015029970A2
Authority
BR
Brazil
Prior art keywords
kinase inhibitors
compositions
compounds
treatment
inter alia
Prior art date
Application number
BR112015029970A
Other languages
English (en)
Inventor
Peter Cridland Andrew
Stephen Robert Jennings Andrew
Hurley Christopher
Alcaraz Lilian
Original Assignee
Chiesi Farm Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Chiesi Farm Spa filed Critical Chiesi Farm Spa
Publication of BR112015029970A2 publication Critical patent/BR112015029970A2/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C53/00—Saturated compounds having only one carboxyl group bound to an acyclic carbon atom or hydrogen
    • C07C53/02—Formic acid
    • C07C53/06—Salts thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D519/00—Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pulmonology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

resumo patente de invenção: "inibidores de cinase". esta invenção refere-se a compostos e composições que são inibidores de p38 mapk, úteis como agentes anti-inflamatórios no tratamento de, inter alia, doenças do trato respiratório.
BR112015029970A 2013-06-06 2014-06-05 inibidores de cinase BR112015029970A2 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP13170937 2013-06-06
PCT/EP2014/061683 WO2014195402A1 (en) 2013-06-06 2014-06-05 Kinase inhibitors

Publications (1)

Publication Number Publication Date
BR112015029970A2 true BR112015029970A2 (pt) 2017-07-25

Family

ID=48569997

Family Applications (1)

Application Number Title Priority Date Filing Date
BR112015029970A BR112015029970A2 (pt) 2013-06-06 2014-06-05 inibidores de cinase

Country Status (10)

Country Link
US (2) US9181242B2 (pt)
EP (1) EP3004097B1 (pt)
KR (1) KR20160018567A (pt)
CN (1) CN105377847A (pt)
AR (1) AR096532A1 (pt)
BR (1) BR112015029970A2 (pt)
CA (1) CA2914432A1 (pt)
HK (1) HK1220459A1 (pt)
RU (1) RU2015151886A (pt)
WO (1) WO2014195402A1 (pt)

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BR112015029504A2 (pt) * 2013-06-06 2017-07-25 Chiesi Farm Spa inibidores quinase
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AR107165A1 (es) 2015-12-23 2018-03-28 Chiesi Farm Spa Inhibidores de quinasa
AR107163A1 (es) 2015-12-23 2018-03-28 Chiesi Farm Spa Inhibidores de quinasa
US10364245B2 (en) 2017-06-07 2019-07-30 Chiesi Farmaceutici S.P.A. Kinase inhibitors
SG10202110259QA (en) 2017-10-05 2021-10-28 Fulcrum Therapeutics Inc Use of p38 inhibitors to reduce expression of dux4
US10342786B2 (en) 2017-10-05 2019-07-09 Fulcrum Therapeutics, Inc. P38 kinase inhibitors reduce DUX4 and downstream gene expression for the treatment of FSHD
CN108424372B (zh) * 2018-05-11 2021-08-10 浙江华贝药业有限责任公司 2，2，2-三氟-n-[(s)-4-羰基四氢萘-1-基]-乙酰胺的纯化工艺
US11066404B2 (en) 2018-10-11 2021-07-20 Incyte Corporation Dihydropyrido[2,3-d]pyrimidinone compounds as CDK2 inhibitors
US11034669B2 (en) 2018-11-30 2021-06-15 Nuvation Bio Inc. Pyrrole and pyrazole compounds and methods of use thereof
US11384083B2 (en) 2019-02-15 2022-07-12 Incyte Corporation Substituted spiro[cyclopropane-1,5′-pyrrolo[2,3-d]pyrimidin]-6′(7′h)-ones as CDK2 inhibitors
WO2020180959A1 (en) 2019-03-05 2020-09-10 Incyte Corporation Pyrazolyl pyrimidinylamine compounds as cdk2 inhibitors
WO2020205560A1 (en) 2019-03-29 2020-10-08 Incyte Corporation Sulfonylamide compounds as cdk2 inhibitors
WO2020223558A1 (en) 2019-05-01 2020-11-05 Incyte Corporation Tricyclic amine compounds as cdk2 inhibitors
WO2020223469A1 (en) 2019-05-01 2020-11-05 Incyte Corporation N-(1-(methylsulfonyl)piperidin-4-yl)-4,5-di hydro-1h-imidazo[4,5-h]quinazolin-8-amine derivatives and related compounds as cyclin-dependent kinase 2 (cdk2) inhibitors for treating cancer
EP4013750A1 (en) 2019-08-14 2022-06-22 Incyte Corporation Imidazolyl pyrimidinylamine compounds as cdk2 inhibitors
WO2021072232A1 (en) 2019-10-11 2021-04-15 Incyte Corporation Bicyclic amines as cdk2 inhibitors
US11981671B2 (en) 2021-06-21 2024-05-14 Incyte Corporation Bicyclic pyrazolyl amines as CDK2 inhibitors
US11976073B2 (en) 2021-12-10 2024-05-07 Incyte Corporation Bicyclic amines as CDK2 inhibitors

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KR20160015221A (ko) 2013-06-06 2016-02-12 키에시 파르마슈티시 엣스. 피. 에이. 키나아제 억제제
KR20160018567A (ko) * 2013-06-06 2016-02-17 키에시 파르마슈티시 엣스. 피. 에이. 키나아제 억제제

Also Published As

Publication number Publication date
KR20160018567A (ko) 2016-02-17
WO2014195402A1 (en) 2014-12-11
US20140364412A1 (en) 2014-12-11
HK1220459A1 (zh) 2017-05-05
RU2015151886A (ru) 2017-06-08
US20160016953A1 (en) 2016-01-21
RU2015151886A3 (pt) 2018-03-30
AR096532A1 (es) 2016-01-13
EP3004097B1 (en) 2018-01-17
CA2914432A1 (en) 2014-12-11
EP3004097A1 (en) 2016-04-13
US9181242B2 (en) 2015-11-10
US9440974B2 (en) 2016-09-13
CN105377847A (zh) 2016-03-02

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Legal Events

Date Code Title Description
B07D Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette]
B08F Application fees: application dismissed [chapter 8.6 patent gazette]

Free format text: REFERENTE A 5A ANUIDADE.

B07E Notice of approval relating to section 229 industrial property law [chapter 7.5 patent gazette]

Free format text: NOTIFICACAO DE ANUENCIA RELACIONADA COM O ART 229 DA LPI

B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: EM VIRTUDE DO ARQUIVAMENTO PUBLICADO NA RPI 2517 DE 02-04-2019 E CONSIDERANDO AUSENCIA DE MANIFESTACAO DENTRO DOS PRAZOS LEGAIS, INFORMO QUE CABE SER MANTIDO O ARQUIVAMENTO DO PEDIDO DE PATENTE, CONFORME O DISPOSTO NO ARTIGO 12, DA RESOLUCAO 113/2013.

B350 Update of information on the portal [chapter 15.35 patent gazette]