HK1220459A1 - 激酶抑制劑 - Google Patents

激酶抑制劑

Info

Publication number
HK1220459A1
HK1220459A1 HK16108561.4A HK16108561A HK1220459A1 HK 1220459 A1 HK1220459 A1 HK 1220459A1 HK 16108561 A HK16108561 A HK 16108561A HK 1220459 A1 HK1220459 A1 HK 1220459A1
Authority
HK
Hong Kong
Prior art keywords
kinase inhibitors
kinase
inhibitors
Prior art date
Application number
HK16108561.4A
Other languages
English (en)
Inventor
．阿爾卡拉斯
．赫爾利
．克裡蒂蘭德
．詹寧斯
Original Assignee
Chiesi Farm Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Chiesi Farm Spa filed Critical Chiesi Farm Spa
Publication of HK1220459A1 publication Critical patent/HK1220459A1/zh

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C53/00—Saturated compounds having only one carboxyl group bound to an acyclic carbon atom or hydrogen
    • C07C53/02—Formic acid
    • C07C53/06—Salts thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D519/00—Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00
HK16108561.4A 2013-06-06 2016-07-19 激酶抑制劑 HK1220459A1 (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP13170937 2013-06-06
PCT/EP2014/061683 WO2014195402A1 (en) 2013-06-06 2014-06-05 Kinase inhibitors

Publications (1)

Publication Number Publication Date
HK1220459A1 true HK1220459A1 (zh) 2017-05-05

Family

ID=48569997

Family Applications (1)

Application Number Title Priority Date Filing Date
HK16108561.4A HK1220459A1 (zh) 2013-06-06 2016-07-19 激酶抑制劑

Country Status (10)

Country Link
US (2) US9181242B2 (zh)
EP (1) EP3004097B1 (zh)
KR (1) KR20160018567A (zh)
CN (1) CN105377847A (zh)
AR (1) AR096532A1 (zh)
BR (1) BR112015029970A2 (zh)
CA (1) CA2914432A1 (zh)
HK (1) HK1220459A1 (zh)
RU (1) RU2015151886A (zh)
WO (1) WO2014195402A1 (zh)

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DK2788349T3 (en) 2011-12-09 2017-01-30 Chiesi Farm Spa kinase inhibitors
CN105377847A (zh) * 2013-06-06 2016-03-02 奇斯药制品公司 激酶抑制剂
KR20160015221A (ko) * 2013-06-06 2016-02-12 키에시 파르마슈티시 엣스. 피. 에이. 키나아제 억제제
BR112015029504A2 (pt) * 2013-06-06 2017-07-25 Chiesi Farm Spa inibidores quinase
EP3394058B1 (en) 2015-12-23 2020-10-14 Chiesi Farmaceutici S.p.A. N-[3-(3-{4-[[1,2,4]triazolo[4,3-a]pyridin-6-yloxy]-1,2,3,4-tetrahydro-naphthalen-1-yl} -ureido)-phenyl]-methanesulfonamide derivatives and their use as p38 mapk inhibitors
TW201730189A (zh) 2015-12-23 2017-09-01 吉斯藥品公司 激酶抑制劑
US10364245B2 (en) 2017-06-07 2019-07-30 Chiesi Farmaceutici S.P.A. Kinase inhibitors
US10342786B2 (en) 2017-10-05 2019-07-09 Fulcrum Therapeutics, Inc. P38 kinase inhibitors reduce DUX4 and downstream gene expression for the treatment of FSHD
CA3128468A1 (en) 2017-10-05 2019-04-11 Fulcrum Therapeutics, Inc. P38 kinase inhibitors reduce dux4 and downstream gene expression for the treatment of fshd
CN108424372B (zh) * 2018-05-11 2021-08-10 浙江华贝药业有限责任公司 2，2，2-三氟-n-[(s)-4-羰基四氢萘-1-基]-乙酰胺的纯化工艺
US11066404B2 (en) 2018-10-11 2021-07-20 Incyte Corporation Dihydropyrido[2,3-d]pyrimidinone compounds as CDK2 inhibitors
WO2020113094A1 (en) 2018-11-30 2020-06-04 Nuvation Bio Inc. Pyrrole and pyrazole compounds and methods of use thereof
WO2020168197A1 (en) 2019-02-15 2020-08-20 Incyte Corporation Pyrrolo[2,3-d]pyrimidinone compounds as cdk2 inhibitors
US11472791B2 (en) 2019-03-05 2022-10-18 Incyte Corporation Pyrazolyl pyrimidinylamine compounds as CDK2 inhibitors
US11919904B2 (en) 2019-03-29 2024-03-05 Incyte Corporation Sulfonylamide compounds as CDK2 inhibitors
WO2020223469A1 (en) 2019-05-01 2020-11-05 Incyte Corporation N-(1-(methylsulfonyl)piperidin-4-yl)-4,5-di hydro-1h-imidazo[4,5-h]quinazolin-8-amine derivatives and related compounds as cyclin-dependent kinase 2 (cdk2) inhibitors for treating cancer
WO2020223558A1 (en) 2019-05-01 2020-11-05 Incyte Corporation Tricyclic amine compounds as cdk2 inhibitors
US11427567B2 (en) 2019-08-14 2022-08-30 Incyte Corporation Imidazolyl pyrimidinylamine compounds as CDK2 inhibitors
KR20220099970A (ko) 2019-10-11 2022-07-14 인사이트 코포레이션 Cdk2 억제제로서의 이환식 아민

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WO2010094956A1 (en) * 2009-02-17 2010-08-26 Pulmagen Therapeutics (Inflammation) Limited. Triazolopyridine derivatives as p38 map kinase inhibitors
GB0902648D0 (en) 2009-02-17 2009-04-01 Argenta Discovery Ltd Pharmaceutical compounds and compositions
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KR20140103925A (ko) 2011-12-09 2014-08-27 키에시 파르마슈티시 엣스. 피. 에이. 4-히드록시-1,2,3,4-테트라히드로나프탈렌-1-일 우레아 및 호흡기 질환의 치료에서의 이들의 용도
DK2788349T3 (en) * 2011-12-09 2017-01-30 Chiesi Farm Spa kinase inhibitors
SG11201402986RA (en) * 2011-12-09 2014-12-30 Chiesi Farma Spa Kinase inhibitors
CN105377847A (zh) * 2013-06-06 2016-03-02 奇斯药制品公司 激酶抑制剂
KR20160015221A (ko) 2013-06-06 2016-02-12 키에시 파르마슈티시 엣스. 피. 에이. 키나아제 억제제

Also Published As

Publication number Publication date
EP3004097A1 (en) 2016-04-13
CN105377847A (zh) 2016-03-02
KR20160018567A (ko) 2016-02-17
RU2015151886A3 (zh) 2018-03-30
US9181242B2 (en) 2015-11-10
US20140364412A1 (en) 2014-12-11
CA2914432A1 (en) 2014-12-11
EP3004097B1 (en) 2018-01-17
BR112015029970A2 (pt) 2017-07-25
AR096532A1 (es) 2016-01-13
US9440974B2 (en) 2016-09-13
WO2014195402A1 (en) 2014-12-11
RU2015151886A (ru) 2017-06-08
US20160016953A1 (en) 2016-01-21

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