IL142397A0 - Method for producing chiral carboxylic acids from nitriles with the assistance of a nitrilase or microorganisms which contain a gene for the nitrilase - Google Patents

Method for producing chiral carboxylic acids from nitriles with the assistance of a nitrilase or microorganisms which contain a gene for the nitrilase

Info

Publication number
IL142397A0
IL142397A0 IL14239799A IL14239799A IL142397A0 IL 142397 A0 IL142397 A0 IL 142397A0 IL 14239799 A IL14239799 A IL 14239799A IL 14239799 A IL14239799 A IL 14239799A IL 142397 A0 IL142397 A0 IL 142397A0
Authority
IL
Israel
Prior art keywords
nucleic acid
nitrilase
acid sequences
microorganisms
carboxylic acids
Prior art date
Application number
IL14239799A
Other languages
English (en)
Original Assignee
Basf Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Basf Ag filed Critical Basf Ag
Publication of IL142397A0 publication Critical patent/IL142397A0/xx

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H21/00Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/11DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/52Genes encoding for enzymes or proenzymes
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14Hydrolases (3)
    • C12N9/78Hydrolases (3) acting on carbon to nitrogen bonds other than peptide bonds (3.5)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P41/00Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture
    • C12P41/006Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture by reactions involving C-N bonds, e.g. nitriles, amides, hydantoins, carbamates, lactames, transamination reactions, or keto group formation from racemic mixtures
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00Preparation of oxygen-containing organic compounds
    • C12P7/40Preparation of oxygen-containing organic compounds containing a carboxyl group including Peroxycarboxylic acids
    • C12P7/42Hydroxy-carboxylic acids

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  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Biomedical Technology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • Analytical Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Plant Pathology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Enzymes And Modification Thereof (AREA)
IL14239799A 1998-10-19 1999-10-13 Method for producing chiral carboxylic acids from nitriles with the assistance of a nitrilase or microorganisms which contain a gene for the nitrilase IL142397A0 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19848129A DE19848129A1 (de) 1998-10-19 1998-10-19 Verfahren zur Herstellung chiraler Carbonsäuren aus Nitrilen mit Hilfe einer Nitrilase oder Mikroorganismen, die ein Gen für die Nitrilase enthalten
PCT/EP1999/007679 WO2000023577A1 (de) 1998-10-19 1999-10-13 Verfahren zur herstellung chiraler carbonsäuren aus nitrilen mit hilfe einer nitrilase oder mikroorganismen, die ein gen für die nitrilase enthalten

Publications (1)

Publication Number Publication Date
IL142397A0 true IL142397A0 (en) 2002-03-10

Family

ID=7884933

Family Applications (2)

Application Number Title Priority Date Filing Date
IL14239799A IL142397A0 (en) 1998-10-19 1999-10-13 Method for producing chiral carboxylic acids from nitriles with the assistance of a nitrilase or microorganisms which contain a gene for the nitrilase
IL142397A IL142397A (en) 1998-10-19 2001-04-03 Process for the formation of nitrile acrylic carboxylic acids using nitrilase or microorganisms containing a nitrilase gene

Family Applications After (1)

Application Number Title Priority Date Filing Date
IL142397A IL142397A (en) 1998-10-19 2001-04-03 Process for the formation of nitrile acrylic carboxylic acids using nitrilase or microorganisms containing a nitrilase gene

Country Status (21)

Country Link
US (1) US6869783B1 (cs)
EP (1) EP1123386B1 (cs)
JP (1) JP4489298B2 (cs)
KR (1) KR100715744B1 (cs)
CN (1) CN100422319C (cs)
AT (1) ATE349517T1 (cs)
AU (1) AU765480B2 (cs)
BR (1) BR9914629A (cs)
CA (1) CA2347521C (cs)
CZ (1) CZ302494B6 (cs)
DE (2) DE19848129A1 (cs)
DK (1) DK1123386T3 (cs)
EE (1) EE05008B1 (cs)
ES (1) ES2280125T3 (cs)
HU (1) HU228092B1 (cs)
ID (1) ID29136A (cs)
IL (2) IL142397A0 (cs)
NO (1) NO327857B1 (cs)
PT (1) PT1123386E (cs)
WO (1) WO2000023577A1 (cs)
ZA (1) ZA200104066B (cs)

Families Citing this family (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19848129A1 (de) * 1998-10-19 2000-04-20 Basf Ag Verfahren zur Herstellung chiraler Carbonsäuren aus Nitrilen mit Hilfe einer Nitrilase oder Mikroorganismen, die ein Gen für die Nitrilase enthalten
WO2003000840A2 (en) 2001-06-21 2003-01-03 Diversa Corporation Nitrilases
US20040002147A1 (en) * 1999-12-29 2004-01-01 Desantis Grace Nitrilases
DE10010149A1 (de) * 2000-03-03 2001-09-06 Basf Ag Nitrilase aus Rhodococcus rhodochrous NCIMB 11216
US6455730B1 (en) 2000-08-04 2002-09-24 E. I. Du Pont De Nemours & Company Preparation of dicarboxylic acid monoesters from cyanocarboxylic acid esters
US6562603B2 (en) 2000-08-04 2003-05-13 E. I. Du Pont De Nemours And Company 3-hydroxycarboxylic acid production and use in branched polymers
US20020137153A1 (en) * 2000-10-04 2002-09-26 Ramer Sandra W. Enantioselective production of amino carboxylic acids
FR2822460B1 (fr) * 2001-03-26 2005-04-29 Rhodia Chimie Sa Procede de preparation enantioselectif d'acides carboxyliques optiquement actifs par hydrolyse enzymatique de nitriles
ITMI20011826A1 (it) * 2001-08-30 2003-03-02 Istituto Biochimico Italiano Microorganismo dotato di attivita' nitrile-idratasica/amidasica enantioselettiva e regioselettiva
DE50307835D1 (de) 2002-12-02 2007-09-13 Basf Ag L-rhamnose-induzierbare expressionssysteme
JP4551224B2 (ja) * 2003-01-08 2010-09-22 ビーエーエスエフ ソシエタス・ヨーロピア ニトリラーゼ又はニトリルヒドラターゼ活性を有する細胞を保存及び/又は貯蔵する方法
DE602004021778D1 (de) * 2003-02-27 2009-08-13 Basf Se Modifizierte nitrilasen und deren verwendung in verfahren zur herstellung von carbonsäuren
AT412092B (de) * 2003-02-27 2004-09-27 Dsm Fine Chem Austria Gmbh Verfahren zur herstellung chiraler alpha-hydroxycarbonsäuren durch enzymatische hydrolyse von chiralen cyanhydrinen
CN102899362B (zh) * 2004-12-22 2014-06-04 纳幕尔杜邦公司 乙醇酸的酶促生产
US20100267100A1 (en) * 2007-03-21 2010-10-21 Ling Hua Enzymatic synthesis of optically pure beta-hydroxy carboxylic acids and their derivatives
US20090004720A1 (en) * 2007-06-26 2009-01-01 Ling Hua Smart Biocatalysts For Organic Synthesis
EP2338987A1 (en) 2009-11-16 2011-06-29 ZYRUS Beteiligungsgesellschaft mbH & Co. Patente I KG Whole cell biocatalyst
JP2013162746A (ja) * 2010-05-24 2013-08-22 Mitsui Chemicals Inc アミド化合物の製造方法
WO2012069434A1 (de) 2010-11-24 2012-05-31 Basf Se Verfahren zur herstellung n-heterozyklischer optisch aktiver alkohole
KR101223663B1 (ko) * 2011-01-26 2013-01-21 재단법인 경북해양바이오산업연구원 나이트릴레이즈 vmn1을 이용한 카르복실산의 제조방법
KR101223664B1 (ko) * 2011-01-26 2013-01-17 재단법인 경북해양바이오산업연구원 나이트릴레이즈 rmn1을 이용한 카르복실산의 제조방법
KR101223665B1 (ko) * 2011-01-26 2013-01-17 재단법인 경북해양바이오산업연구원 나이트릴레이즈 rmn2을 이용한 카르복실산의 제조방법
KR101223666B1 (ko) * 2011-01-26 2013-01-17 재단법인 경북해양바이오산업연구원 나이트릴레이즈 orn을 이용한 카르복실산의 제조방법
WO2021229106A1 (en) 2020-05-15 2021-11-18 Basf Se Improved method for the production of isoprenoids
AR127935A1 (es) 2021-12-10 2024-03-13 Basf Se Descarbamoilación enzimática de derivados de glufosinato
CA3240073A1 (en) 2021-12-10 2023-06-15 Klaus Ditrich Herbicidal activity of alkyl phosphinates
CA3240053A1 (en) 2021-12-10 2023-06-15 Klaus Ditrich Synthesis of glufosinate using a hydantoinase-based process

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EP0332379B1 (en) 1988-03-08 1996-08-14 Japan Energy Corporation Production process of L-alpha-amino acids
US5283193A (en) 1988-06-27 1994-02-01 Asahi Kasei Kogyo K.K. Process for producing optically active α-substituted organic acid and microorganism and enzyme used therefor
DK314989A (da) 1988-06-27 1989-12-28 Asahi Chemical Ind Fremgangsmaade til fremstilling af optisk aktive alfa-substituerede organiske syrer, samt mikroorganismer og enzymer anvendelige ved fremgangsmaaden
JPH0219577A (ja) 1988-07-04 1990-01-23 Nippon Saafuakutanto Kogyo Kk 反応染料用均染剤組成物
DE69131217T2 (de) 1990-03-30 1999-09-23 Mitsubishi Rayon Co Verfahren zur Herstellung von R(-)Mandelsäure und deren Derivaten
JP2974737B2 (ja) 1990-08-16 1999-11-10 三菱レイヨン株式会社 光学活性乳酸の製造法
DK0549710T3 (da) 1990-09-20 1996-03-18 Du Pont Fremgangsmåde til fremstilling af enantiomere 2-alkansyrer
JP2676568B2 (ja) 1991-06-26 1997-11-17 日東化学工業株式会社 R(−)−マンデル酸およびその誘導体の製造法
JP3093056B2 (ja) * 1992-11-17 2000-10-03 三菱レイヨン株式会社 ニトリラーゼ活性を有するポリペプチドをコードする遺伝子dnaを含有する形質転換体による有機酸の製造法
JP3218133B2 (ja) 1993-02-03 2001-10-15 三菱レイヨン株式会社 フェニル基を有する光学活性α−ヒドロキシカルボン酸の製造法
JP2720140B2 (ja) 1993-02-03 1998-02-25 日東化学工業株式会社 フェニル基を有する光学活性α−ヒドロキシカルボン酸の製造法
JP3354688B2 (ja) 1994-01-28 2002-12-09 三菱レイヨン株式会社 微生物によるα−ヒドロキシ酸またはα−ヒドロキシアミドの製造法
JP3154633B2 (ja) 1994-12-28 2001-04-09 三菱レイヨン株式会社 ニトリラーゼ遺伝子発現のための調節因子およびその遺伝子
WO1997032030A1 (fr) 1996-02-29 1997-09-04 Nippon Soda Co., Ltd. PROCESSUS DE PREPARATION D'ACIDES α-HYDROXY A L'AIDE D'UN MICRO-ORGANISME ET NOUVEAU MICRO-ORGANISME
DE19848129A1 (de) * 1998-10-19 2000-04-20 Basf Ag Verfahren zur Herstellung chiraler Carbonsäuren aus Nitrilen mit Hilfe einer Nitrilase oder Mikroorganismen, die ein Gen für die Nitrilase enthalten

Also Published As

Publication number Publication date
EP1123386A1 (de) 2001-08-16
ATE349517T1 (de) 2007-01-15
EE05008B1 (et) 2008-04-15
CZ20011382A3 (cs) 2002-03-13
NO20011912L (no) 2001-04-18
HUP0104802A3 (en) 2005-10-28
HU228092B1 (en) 2012-10-29
BR9914629A (pt) 2001-06-26
CA2347521C (en) 2010-02-23
DE59914102D1 (de) 2007-02-08
ZA200104066B (en) 2002-07-01
CN100422319C (zh) 2008-10-01
PT1123386E (pt) 2007-03-30
DK1123386T3 (da) 2007-05-07
CN1331743A (zh) 2002-01-16
NO20011912D0 (no) 2001-04-18
WO2000023577A1 (de) 2000-04-27
JP2002527106A (ja) 2002-08-27
EP1123386B1 (de) 2006-12-27
KR20010085938A (ko) 2001-09-07
ES2280125T3 (es) 2007-09-01
NO327857B1 (no) 2009-10-05
AU765480B2 (en) 2003-09-18
US6869783B1 (en) 2005-03-22
CA2347521A1 (en) 2000-04-27
IL142397A (en) 2008-03-20
HUP0104802A2 (hu) 2002-04-29
CZ302494B6 (cs) 2011-06-15
ID29136A (id) 2001-08-02
AU6470899A (en) 2000-05-08
KR100715744B1 (ko) 2007-05-08
EE200100232A (et) 2002-08-15
JP4489298B2 (ja) 2010-06-23
DE19848129A1 (de) 2000-04-20

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