MX291457B - Metodos para producir acidos carboxilicos alfa-sustituidos, enantiomericamente puros. - Google Patents

Metodos para producir acidos carboxilicos alfa-sustituidos, enantiomericamente puros.

Info

Publication number
MX291457B
MX291457B MXPA01008736A MX291457B MX 291457 B MX291457 B MX 291457B MX PA01008736 A MXPA01008736 A MX PA01008736A MX 291457 B MX291457 B MX 291457B
Authority
MX
Mexico
Prior art keywords
enantiomerically pure
carboxylic acids
substituted carboxylic
methods
producing enantiomerically
Prior art date
Application number
Other languages
English (en)
Inventor
Madden Darcy
Original Assignee
Diversa Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Diversa Corp filed Critical Diversa Corp
Publication of MXPA01008736A publication Critical patent/MXPA01008736A/es
Publication of MX291457B publication Critical patent/MX291457B/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/78—Hydrolases (3) acting on carbon to nitrogen bonds other than peptide bonds (3.5)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00—Preparation of nitrogen-containing organic compounds
    • C12P13/002—Nitriles (-CN)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00—Preparation of nitrogen-containing organic compounds
    • C12P13/04—Alpha- or beta- amino acids
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P41/00—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture
    • C12P41/006—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture by reactions involving C-N bonds, e.g. nitriles, amides, hydantoins, carbamates, lactames, transamination reactions, or keto group formation from racemic mixtures
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/40—Preparation of oxygen-containing organic compounds containing a carboxyl group including Peroxycarboxylic acids
    • C12P7/42—Hydroxy-carboxylic acids
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y305/00—Hydrolases acting on carbon-nitrogen bonds, other than peptide bonds (3.5)
    • C12Y305/05—Hydrolases acting on carbon-nitrogen bonds, other than peptide bonds (3.5) in nitriles (3.5.5)
    • C12Y305/05001—Nitrilase (3.5.5.1)
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/52—Improvements relating to the production of bulk chemicals using catalysts, e.g. selective catalysts

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Analytical Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Plant Pathology (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
MXPA01008736 1999-12-29 2000-12-29 Metodos para producir acidos carboxilicos alfa-sustituidos, enantiomericamente puros. MX291457B (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US17360999P 1999-12-29 1999-12-29
US25441400P 2000-12-07 2000-12-07
PCT/US2000/035555 WO2001048175A2 (en) 1999-12-29 2000-12-29 METHODS FOR PRODUCING ENANTIOMERICALLY PURE α-SUBSTITUTED CARBOXYLIC ACIDS

Publications (2)

Publication Number Publication Date
MXPA01008736A MXPA01008736A (es) 2002-06-21
MX291457B true MX291457B (es) 2011-10-28

Family

ID=26869344

Family Applications (1)

Application Number Title Priority Date Filing Date
MXPA01008736 MX291457B (es) 1999-12-29 2000-12-29 Metodos para producir acidos carboxilicos alfa-sustituidos, enantiomericamente puros.

Country Status (9)

Country Link
US (9) US7300775B2 (es)
EP (2) EP2258840A1 (es)
JP (1) JP4261799B2 (es)
AU (1) AU785076B2 (es)
CA (2) CA2718302C (es)
HK (1) HK1050216B (es)
IL (1) IL145054A0 (es)
MX (1) MX291457B (es)
WO (1) WO2001048175A2 (es)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7521216B2 (en) 1999-12-29 2009-04-21 Verenium Corporation Nitrilases and methods for making and using them
US20040002147A1 (en) * 1999-12-29 2004-01-01 Desantis Grace Nitrilases
US7608445B1 (en) 1999-12-29 2009-10-27 Verenium Corporation Nitrilases, nucleic acids encoding them and methods for making and using them
US7300775B2 (en) 1999-12-29 2007-11-27 Verenium Corporation Methods for producing α-substituted carboxylic acids using nitrilases and strecker reagents
DK2327767T3 (en) * 2001-06-21 2015-07-27 Basf Enzymes Llc nitrilases
US7932064B2 (en) 2002-06-13 2011-04-26 Verenium Corporation Processes for making (R)-ethyl 4-cyano-3-hydroxybutyric acid
JP4584242B2 (ja) 2003-02-27 2010-11-17 ビーエーエスエフ ソシエタス・ヨーロピア 改変されたニトリラーゼおよびカルボン酸の製造方法におけるその使用
CN101166524B (zh) 2005-04-28 2010-12-22 辉瑞有限公司 氨基酸衍生物
WO2008106662A2 (en) * 2007-03-01 2008-09-04 Verenium Corporation Nitrilases, nucleic acids encoding them and methods for making and using them
US8247436B2 (en) 2010-03-19 2012-08-21 Novartis Ag Pyridine and pyrazine derivative for the treatment of CF
KR101223665B1 (ko) * 2011-01-26 2013-01-17 재단법인 경북해양바이오산업연구원 나이트릴레이즈 ｒｍｎ２을 이용한 카르복실산의 제조방법
KR101719035B1 (ko) * 2014-09-19 2017-03-23 포항공과대학교 산학협력단 신규 효소를 사용한 d형 젖산의 제조
MX2018004674A (es) * 2015-10-23 2018-09-11 Navitor Pharm Inc Moduladores de interacción de sestrina-gator2 y sus usos.
EP3522713B1 (en) * 2016-10-03 2022-11-30 Illumina, Inc. Fluorescent detection of amines and hydrazines and assaying methods thereof
WO2018156094A1 (en) 2017-02-24 2018-08-30 Murat Can Emission reducer fuel saving apparatus
CN113195727A (zh) * 2018-10-18 2021-07-30 巴斯夫欧洲公司 用于产生丙烯酸或其盐的方法
US20240002787A1 (en) * 2022-06-30 2024-01-04 Battelle Savannah River Alliance, Llc Porous glass-based microbial storage and delivery system

Family Cites Families (65)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6019496A (ja) 1983-07-12 1985-01-31 Nitto Chem Ind Co Ltd 微生物によるアミド類の製造法
CN85107055A (zh) 1984-10-01 1986-06-10 诺沃工业联合股票公司 酶促工艺方法
JPS61162195A (ja) 1985-01-11 1986-07-22 Nitto Chem Ind Co Ltd 微生物によるアミド類の製造法
US4611067A (en) 1985-01-31 1986-09-09 Merck & Co., Inc. Process for the preparation of HMG-CoA reductase inhibitors and intermediate compounds employed therein
DK261685A (da) 1985-06-11 1986-12-12 Novo Industri As Fremgangsmaade til fremstilling af optisk aktive, organiske forbindelser
US5206158A (en) 1986-07-02 1993-04-27 Gist-Brocades N.V. Process for the preparation of difluorobenzamide
US4946778A (en) 1987-09-21 1990-08-07 Genex Corporation Single polypeptide chain binding molecules
US5149837A (en) 1988-02-22 1992-09-22 Warner-Lambert Company Process for trans-6-[2-(substituted-pyrrol-1-yl)alkyl]pyran-2-one inhibitors of cholesterol synthesis
US5216174A (en) * 1988-02-22 1993-06-01 Warner-Lambert Co. Process for trans-6-[12-(substituted-pyrrol-1-yl)alkyl]pyran-2-one inhibitors of cholesterol synthesis
US5245047A (en) * 1988-02-22 1993-09-14 Warner-Lambert Company Process for trans-6-[2-(substituted-pyrrol-1-yl)alkyl]pyran-2-one inhibitors of cholesterol synthesis
US5124482A (en) 1988-02-22 1992-06-23 Warner-Lambert Company Process for trans-6-(2-substituted-pyrrol-1-yl)alkyl)pyran-2-one inhibitors of cholesterol synthesis
US5097045A (en) 1989-02-01 1992-03-17 Warner-Lambert Company Process for trans-6-[2-(substituted-pyrrol-1-yl)alkyl]pyran-2-one inhibitors of cholesterol synthesis
US5003080A (en) * 1988-02-22 1991-03-26 Warner-Lambert Company Process for trans-6-(2-(substituted-pyrrol-1-yl)alkyl)pryan-2-one inhibitors of cholesterol synthesis
EP0332379B1 (en) 1988-03-08 1996-08-14 Japan Energy Corporation Production process of L-alpha-amino acids
JPH0479894A (ja) 1990-07-19 1992-03-13 Nikko Kyodo Co Ltd Ｄ―アラニンの製造方法
US5587303A (en) 1988-03-08 1996-12-24 Nippon Mining Company, Ltd. Production process of L-amino acids with bacteria
JP2670838B2 (ja) 1988-03-08 1997-10-29 株式会社ジャパンエナジー Ｌ―α―アミノ酸類の製造方法
EP0814166A3 (en) 1989-08-09 1998-05-13 DeKalb Genetics Corporation Methods and compositions for the production of stably transformed fertile monocot plants and cells thereof
DK589389D0 (da) 1989-11-23 1989-11-23 Novo Nordisk As Immobiliseret enzympraeparat
CA2030900A1 (en) 1989-11-27 1991-05-28 Dennis Gordon Kleid Processes to recoverand reconcentrate gold from its ores
BR9007196A (pt) * 1989-12-22 1991-12-10 Gen Electric Composicao
JP2696424B2 (ja) 1990-08-16 1998-01-14 日東化学工業株式会社 Ｒ（‐）―マンデル酸の製造法
EP0449648B1 (en) 1990-03-30 1999-05-12 Nitto Chemical Industry Co., Ltd. Process for producing R(-)-mandelic acid and derivatives thereof
EP0528881A4 (en) 1990-04-24 1993-05-26 Stratagene Methods for phenotype creation from multiple gene populations
US5103024A (en) 1990-10-17 1992-04-07 Warner-Lambert Company Process for the synthesis of (4r-cis)-1,1-dimethylethyl 6-cyanomethyl-2,2-dimethyl-1,3-dioxane-4-acetate
US5248793A (en) * 1990-10-17 1993-09-28 Warner-Lambert Company Process for the synthesis of (4R-cis)-1,1-dimethylethyl 6-iodomethyl or 6-(phenyl-substituted)sulfonyloxymethyl-2,2-dimethyl-1,3-dioxane-4-acetate
EP0502476B1 (en) 1991-03-04 2001-07-18 Mitsubishi Rayon Co., Ltd. Hybrid plasmid vectors containing genes encoding nitrile degrading enzymes and methods of producing amides and acids
US5837840A (en) 1993-09-20 1998-11-17 Board Of Trustees Of Leland Stanford Jr. University NF-AT polypeptides and polynucleotides
FR2694571B1 (fr) 1992-08-10 1994-11-04 Rhone Poulenc Chimie Polypeptides possédant une activité nitrilase, séquence d'ADN codant pour lesdits polypeptides, cassettes d'expression et micro-organismes hôtes permettant leur obtention.
US5629190A (en) * 1992-08-10 1997-05-13 Rhone-Poulenc Chimie Polypeptides possessing a nitrilase activity and method of converting nitriles to carboxylates by means of said polypeptides
JP3218133B2 (ja) 1993-02-03 2001-10-15 三菱レイヨン株式会社 フェニル基を有する光学活性α−ヒドロキシカルボン酸の製造法
JP2720140B2 (ja) 1993-02-03 1998-02-25 日東化学工業株式会社 フェニル基を有する光学活性α−ヒドロキシカルボン酸の製造法
US5298627A (en) * 1993-03-03 1994-03-29 Warner-Lambert Company Process for trans-6-[2-(substituted-pyrrol-1-yl)alkyl]pyran-2-one inhibitors of cholesterol synthesis
GB9307924D0 (en) 1993-04-16 1993-06-02 Zeneca Ltd Chrial synthesis
JP3119468B2 (ja) 1994-11-09 2000-12-18 三菱レイヨン株式会社 光学活性なα−ヒドロキシ酸またはα−ヒドロキシアミドの製造法
NL1000360C2 (nl) 1995-05-15 1996-11-18 Akzo Nobel Nv Werkwijze ter bereiding van pyridine-2, 6-diamines
US5811515A (en) * 1995-06-12 1998-09-22 California Institute Of Technology Synthesis of conformationally restricted amino acids, peptides, and peptidomimetics by catalytic ring closing metathesis
JPH0937788A (ja) 1995-07-31 1997-02-10 Nitto Chem Ind Co Ltd 新規なニトリラーゼ遺伝子
US5756306A (en) 1995-11-10 1998-05-26 Nitto Chemical Industry Co., Ltd. Process for producing a-hydroxy acid or a-hydroxyamide by microorganism
GB9525372D0 (en) 1995-12-12 1996-02-14 Allied Colloids Ltd Enzymes, their preparation and their use in the production of ammonium acrylate
US5932212A (en) 1996-05-24 1999-08-03 Altus Biologics, Inc. Crosslinked protein crystal formulations and their use as catalysts in organic solvents
WO1998013119A1 (en) 1996-09-24 1998-04-02 Altus Biologics Inc. Crosslinked protein crystals as universal separation media
EP0856579A1 (en) 1997-01-31 1998-08-05 BIOGNOSTIK GESELLSCHAFT FÜR BIOMOLEKULARE DIAGNOSTIK mbH An antisense oligonucleotide preparation method
US20010038444A1 (en) 1998-03-02 2001-11-08 Eastman Kodak Company Detection of pitch variations in lenticular material
NZ504346A (en) * 1997-12-19 2001-11-30 Warner Lambert Exp Ltd Process for the synthesis of 1,3-diols characterised by either reconcentration step with either trialkylborane or dialkylalkoxyborane or a mixture of both trialkylborane and dialkylalkoxyborane
EP2311436A1 (en) 1998-04-27 2011-04-20 Altus Pharmaceuticals Inc. Stabilized protein crystals, formulations containing them and methods of making them
US6492578B1 (en) 1998-07-10 2002-12-10 Calgene Llc Expression of herbicide tolerance genes in plant plastids
WO2000003685A2 (en) 1998-07-20 2000-01-27 Thomas Jefferson University Nitrilase homologs
DE19913858A1 (de) 1999-03-26 2000-09-28 Studiengesellschaft Kohle Mbh High-Throughput-Screening-Verfahren zur Bestimmung der Enantioselektivität asymmetrisch verlaufender Reaktionen
CA2378549A1 (en) 1999-07-10 2001-01-18 Calgene Llc Enhanced expression of proteins
AU6094200A (en) 1999-07-12 2001-03-19 Cornell Research Foundation Inc. Nor gene compositions and methods for use thereof
AUPQ262599A0 (en) 1999-09-02 1999-09-23 University Of Queensland, The Gene expression
WO2001021782A2 (en) 1999-09-24 2001-03-29 Calgene Llc Enhancer elements for increased translation in plant plastids
CN1451045A (zh) 1999-10-07 2003-10-22 马克西根公司 IFN－α同系物
BR0014858A (pt) 1999-10-15 2002-07-16 Calgene Llc Métodos e vetores para recombinação de sìtio especìfico em plastìdios de células de plantas
US20040002147A1 (en) 1999-12-29 2004-01-01 Desantis Grace Nitrilases
US7521216B2 (en) 1999-12-29 2009-04-21 Verenium Corporation Nitrilases and methods for making and using them
US20040014195A1 (en) 1999-12-29 2004-01-22 Diversa Corporation Nitrilases, nucleic acids encoding them and methods for making and using them
US7300775B2 (en) 1999-12-29 2007-11-27 Verenium Corporation Methods for producing α-substituted carboxylic acids using nitrilases and strecker reagents
US20030044800A1 (en) 2000-09-05 2003-03-06 Connelly Patrick R. Drug discovery employing calorimetric target triage
WO2002029079A2 (en) 2000-10-04 2002-04-11 Maxygen, Inc. Enantioselective production of amino carboxylic acids
US20020127609A1 (en) * 2001-02-23 2002-09-12 Maxygen, Inc. Screening for enzyme stereoselectivity utilizing mass spectrometry
DK2327767T3 (en) 2001-06-21 2015-07-27 Basf Enzymes Llc nitrilases
US7199261B2 (en) 2001-07-06 2007-04-03 Teva Pharmaceutical Industries Ltd Process for the preparation of 7-amino syn 3,5-dihydroxy heptanoic acid derivatives via 6-cyano syn 3,5-dihydroxy hexanoic acid derivatives
WO2004096988A2 (en) 2003-04-25 2004-11-11 Dow Global Technologies Inc Discovery of biocatalysts and biocatalytic activities using nuclear magnetic resonance

Also Published As

Publication number Publication date
US20160355801A1 (en) 2016-12-08
US9828594B2 (en) 2017-11-28
US20100216214A1 (en) 2010-08-26
WO2001048175A3 (en) 2002-02-14
US9315792B2 (en) 2016-04-19
CA2718302A1 (en) 2001-07-05
US20090162906A1 (en) 2009-06-25
US20020012974A1 (en) 2002-01-31
US20120009637A1 (en) 2012-01-12
WO2001048175A2 (en) 2001-07-05
EP2258840A1 (en) 2010-12-08
HK1050216A1 (en) 2003-06-13
CA2718302C (en) 2012-12-04
US8034595B2 (en) 2011-10-11
EP1242589A2 (en) 2002-09-25
MXPA01008736A (es) 2002-06-21
US8778651B2 (en) 2014-07-15
EP1242589B1 (en) 2013-11-13
US20130316409A1 (en) 2013-11-28
JP2003521899A (ja) 2003-07-22
US8501451B2 (en) 2013-08-06
US7300775B2 (en) 2007-11-27
IL145054A0 (en) 2002-06-30
US8318471B2 (en) 2012-11-27
JP4261799B2 (ja) 2009-04-30
US20100009426A1 (en) 2010-01-14
US7811804B2 (en) 2010-10-12
US20150125928A1 (en) 2015-05-07
CA2365224A1 (en) 2001-07-05
AU785076B2 (en) 2006-09-14
HK1050216B (zh) 2014-03-07
AU2607001A (en) 2001-07-09
US8088613B2 (en) 2012-01-03
US20120009633A1 (en) 2012-01-12

Similar Documents

Publication Publication Date Title
MX291457B (es) Metodos para producir acidos carboxilicos alfa-sustituidos, enantiomericamente puros.
IL142397A0 (en) Method for producing chiral carboxylic acids from nitriles with the assistance of a nitrilase or microorganisms which contain a gene for the nitrilase
HUP0203704A2 (hu) L-Pankolakton hidroláz és eljárás D-pantolakton előállítására
DE59812638D1 (de) Verfahren zur mikrobiellen herstellung von aminosäuren der aspartat- und/oder glutamatfamilie und im verfahren einsetzbare mittel
DE602004000428D1 (de) Verfahren zur Herstellung von Cadaverindicarboxylat und dessen Verwendung zur Herstellung von Nylon
ATE417094T1 (de) Verfahren zur herstellung von l-aminosäure
EP0773297A3 (en) Process for producing alfa-hydroxy acid or alfa-hydroxyamide by microorganism
WO2002072856A3 (en) Improved process for converting nitriles to carboxylic acids using nitrilase
HUP0201152A2 (hu) Eljárás nem proteinogén L-aminosavak előállítására
ATE312809T1 (de) Verfahren zur herstellung von gabapentin
DE60311456D1 (de) Verfahren zur herstellung von eisenhydroxypyronverbindungen
CA2084855A1 (en) Method of preparing optically active cyanohydrins
ATE435278T1 (de) Modifizierte nitrilasen und deren verwendung in verfahren zur herstellung von carbonsäuren
DE69935880D1 (de) Protein das an einer Aktivierung von Nitril Hydratase teilnimmt,Gen,Plasmid und Verfahren zur Herstellung eines Amid
WO2003066815A3 (en) Method for producing 2-hydroxyisobutyric acid and methacrylic acid from acetone cyanohydrin
ATE282024T1 (de) Verfahren zur herstellung von aminonitrilen
ATE319850T1 (de) Verfahren zur herstellung von aminosäuren
ATE144975T1 (de) Verfahren zur herstellung von alkalimetallcitrat
WO2001038292A3 (de) Verfahren zur herstellung optisch aktiver amine
ATE267265T1 (de) Verfahren zur herstellung von optisch-aktiven 2- omega-oxoalkansäurederivaten
EP0927762A3 (en) Method for removing fumarase activity, Microorganisms obtainable by the method and production of optically active aminopolycarboxylic acids using the microorganisms
WO2002095045A3 (fr) Procede de preparation d'acides carboxyliques aliphatiques par hydrolyse enzymatique de composes nitriles aliphatiques
ATE417919T1 (de) Mikrobiologisches verfahren zur herstellung von amiden
WO2003010312A3 (en) Nucleic acid sequences encoding enantioselective amidases
WO2004090124A3 (en) Sequences encoding s-hydroxynitril lyases and their use in methods for the production of cyanohydrins

Legal Events

Date Code Title Description
GB Transfer or rights
FG Grant or registration