HK1050216B - 產生對映體純正α-替代羧酸的方法 - Google Patents

產生對映體純正α-替代羧酸的方法

Info

Publication number
HK1050216B
HK1050216B HK03101995.0A HK03101995A HK1050216B HK 1050216 B HK1050216 B HK 1050216B HK 03101995 A HK03101995 A HK 03101995A HK 1050216 B HK1050216 B HK 1050216B
Authority
HK
Hong Kong
Prior art keywords
methods
carboxylic acids
enantiomerically pure
substituted carboxylic
pure alpha
Prior art date
Application number
HK03101995.0A
Other languages
English (en)
Other versions
HK1050216A1 (en
Inventor
Mark Madden
David Paul Weiner
Jennifer Ann Chaplin
Robertson Dan
Original Assignee
Verenium Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Verenium Corp filed Critical Verenium Corp
Publication of HK1050216A1 publication Critical patent/HK1050216A1/xx
Publication of HK1050216B publication Critical patent/HK1050216B/zh

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/78—Hydrolases (3) acting on carbon to nitrogen bonds other than peptide bonds (3.5)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00—Preparation of nitrogen-containing organic compounds
    • C12P13/002—Nitriles (-CN)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00—Preparation of nitrogen-containing organic compounds
    • C12P13/04—Alpha- or beta- amino acids
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P41/00—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture
    • C12P41/006—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture by reactions involving C-N bonds, e.g. nitriles, amides, hydantoins, carbamates, lactames, transamination reactions, or keto group formation from racemic mixtures
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/40—Preparation of oxygen-containing organic compounds containing a carboxyl group including Peroxycarboxylic acids
    • C12P7/42—Hydroxy-carboxylic acids
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y305/00—Hydrolases acting on carbon-nitrogen bonds, other than peptide bonds (3.5)
    • C12Y305/05—Hydrolases acting on carbon-nitrogen bonds, other than peptide bonds (3.5) in nitriles (3.5.5)
    • C12Y305/05001—Nitrilase (3.5.5.1)
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/52—Improvements relating to the production of bulk chemicals using catalysts, e.g. selective catalysts

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Analytical Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Plant Pathology (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
HK03101995.0A 1999-12-29 2003-03-18 產生對映體純正α-替代羧酸的方法 HK1050216B (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US17360999P 1999-12-29 1999-12-29
US25441400P 2000-12-07 2000-12-07
PCT/US2000/035555 WO2001048175A2 (en) 1999-12-29 2000-12-29 METHODS FOR PRODUCING ENANTIOMERICALLY PURE α-SUBSTITUTED CARBOXYLIC ACIDS

Publications (2)

Publication Number Publication Date
HK1050216A1 HK1050216A1 (en) 2003-06-13
HK1050216B true HK1050216B (zh) 2014-03-07

Family

ID=26869344

Family Applications (1)

Application Number Title Priority Date Filing Date
HK03101995.0A HK1050216B (zh) 1999-12-29 2003-03-18 產生對映體純正α-替代羧酸的方法

Country Status (9)

Country Link
US (9) US7300775B2 (zh)
EP (2) EP1242589B1 (zh)
JP (1) JP4261799B2 (zh)
AU (1) AU785076B2 (zh)
CA (2) CA2365224A1 (zh)
HK (1) HK1050216B (zh)
IL (1) IL145054A0 (zh)
MX (1) MX291457B (zh)
WO (1) WO2001048175A2 (zh)

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US7300775B2 (en) 1999-12-29 2007-11-27 Verenium Corporation Methods for producing α-substituted carboxylic acids using nitrilases and strecker reagents
EP1578910A4 (en) * 2001-06-21 2008-06-04 Verenium Corp NITRILASES
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KR100925900B1 (ko) 2005-04-28 2009-11-09 화이자 리미티드 아미노산 유도체
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Also Published As

Publication number Publication date
US20100009426A1 (en) 2010-01-14
HK1050216A1 (en) 2003-06-13
CA2718302A1 (en) 2001-07-05
US20020012974A1 (en) 2002-01-31
EP2258840A1 (en) 2010-12-08
MX291457B (es) 2011-10-28
US8034595B2 (en) 2011-10-11
JP4261799B2 (ja) 2009-04-30
AU2607001A (en) 2001-07-09
US20090162906A1 (en) 2009-06-25
CA2365224A1 (en) 2001-07-05
WO2001048175A2 (en) 2001-07-05
US20150125928A1 (en) 2015-05-07
WO2001048175A3 (en) 2002-02-14
US9828594B2 (en) 2017-11-28
EP1242589B1 (en) 2013-11-13
US20120009637A1 (en) 2012-01-12
US7811804B2 (en) 2010-10-12
US20160355801A1 (en) 2016-12-08
EP1242589A2 (en) 2002-09-25
US8318471B2 (en) 2012-11-27
CA2718302C (en) 2012-12-04
US20130316409A1 (en) 2013-11-28
IL145054A0 (en) 2002-06-30
US20100216214A1 (en) 2010-08-26
US8778651B2 (en) 2014-07-15
US7300775B2 (en) 2007-11-27
US20120009633A1 (en) 2012-01-12
US9315792B2 (en) 2016-04-19
JP2003521899A (ja) 2003-07-22
US8501451B2 (en) 2013-08-06
US8088613B2 (en) 2012-01-03
MXPA01008736A (es) 2002-06-21
AU785076B2 (en) 2006-09-14

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