HUP0203704A2 - L-Pankolakton hidroláz és eljárás D-pantolakton előállítására - Google Patents

L-Pankolakton hidroláz és eljárás D-pantolakton előállítására

Info

Publication number
HUP0203704A2
HUP0203704A2 HU0203704A HUP0203704A HUP0203704A2 HU P0203704 A2 HUP0203704 A2 HU P0203704A2 HU 0203704 A HU0203704 A HU 0203704A HU P0203704 A HUP0203704 A HU P0203704A HU P0203704 A2 HUP0203704 A2 HU P0203704A2
Authority
HU
Hungary
Prior art keywords
pantolactone
hydrolase
producing
proteins
deals
Prior art date
Application number
HU0203704A
Other languages
English (en)
Inventor
Thomas Friedrich
Berhard Hauer
Maria Kesseler
Ralf Mattes
Original Assignee
Basf Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DE19952501A external-priority patent/DE19952501A1/de
Priority claimed from DE10029194A external-priority patent/DE10029194A1/de
Application filed by Basf Ag filed Critical Basf Ag
Publication of HUP0203704A2 publication Critical patent/HUP0203704A2/hu
Publication of HUP0203704A3 publication Critical patent/HUP0203704A3/hu

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/52—Genes encoding for enzymes or proenzymes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P17/00—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
    • C12P17/02—Oxygen as only ring hetero atoms
    • C12P17/04—Oxygen as only ring hetero atoms containing a five-membered hetero ring, e.g. griseofulvin, vitamin C
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/16—Hydrolases (3) acting on ester bonds (3.1)
    • C12N9/18—Carboxylic ester hydrolases (3.1.1)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P41/00—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture
    • C12P41/003—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture by ester formation, lactone formation or the inverse reactions
    • C12P41/005—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture by ester formation, lactone formation or the inverse reactions by esterification of carboxylic acid groups in the enantiomers or the inverse reaction

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Molecular Biology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Plant Pathology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Enzymes And Modification Thereof (AREA)

Abstract

A találmány fehérjékkel foglalkozik, amelyek enzimes aktívitártmutatnak L-pantolakton hidrolízisére. A találmány továbbá foglalkozikaz ezen fehérjéket kódoló nukleinsavakkal, nukleinsav konstrukciókkal,vektorokkal, genetikailag megváltoztatott mikroorganizmusokkal,továbbá eljárással D-pantolakton előállítására. Ó
HU0203704A 1999-10-29 2000-10-20 L-pantolactone-hydrolase and a method for producing d-pantolactone HUP0203704A3 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DE19952501A DE19952501A1 (de) 1999-10-29 1999-10-29 L-Pantolacton-Hydrolase und ein Verfahren zur Herstellung von D-Pantolacton
DE10029194A DE10029194A1 (de) 2000-06-19 2000-06-19 L-Pantolacton-Hydrolase und ein Verfahren zur Herstellung von D-Pantolacton
PCT/EP2000/010320 WO2001032890A1 (de) 1999-10-29 2000-10-20 L-pantolacton-hydrolase und ein verfahren zur herstellung von d-pantolacton

Publications (2)

Publication Number Publication Date
HUP0203704A2 true HUP0203704A2 (hu) 2003-03-28
HUP0203704A3 HUP0203704A3 (en) 2006-03-28

Family

ID=26006072

Family Applications (1)

Application Number Title Priority Date Filing Date
HU0203704A HUP0203704A3 (en) 1999-10-29 2000-10-20 L-pantolactone-hydrolase and a method for producing d-pantolactone

Country Status (17)

Country Link
US (1) US6998258B1 (hu)
EP (1) EP1224296A1 (hu)
JP (1) JP2003530080A (hu)
KR (1) KR20020043254A (hu)
CN (1) CN1384880A (hu)
AU (1) AU782517B2 (hu)
BR (1) BR0015114A (hu)
CA (1) CA2389064A1 (hu)
CZ (1) CZ20021449A3 (hu)
EE (1) EE200200225A (hu)
HU (1) HUP0203704A3 (hu)
IL (1) IL148973A0 (hu)
MX (1) MXPA02003417A (hu)
NO (1) NO20021931D0 (hu)
PL (1) PL355487A1 (hu)
RU (1) RU2002114044A (hu)
WO (1) WO2001032890A1 (hu)

Families Citing this family (86)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20030194798A1 (en) * 2001-05-24 2003-10-16 Surber Mark W. Minicell compositions and methods
AU2003288189B8 (en) 2002-12-02 2009-06-25 Basf Aktiengesellschaft L-rhamnose-inducible expression systems
JP4571936B2 (ja) * 2003-03-28 2010-10-27 ディーエスエム アイピー アセッツ ビー．ブイ． パントラクトンヒドロラーゼ
CN101448950B (zh) * 2006-05-16 2014-02-12 帝斯曼知识产权资产管理有限公司 用于生产泛醇的工艺
EP2061897B1 (en) 2006-07-27 2020-03-25 Wyeth LLC High-cell density fed-batch fermentation process for producing recombinant protein
US8399866B2 (en) 2008-05-22 2013-03-19 Vladimir Balakin Charged particle extraction apparatus and method of use thereof
US8368038B2 (en) 2008-05-22 2013-02-05 Vladimir Balakin Method and apparatus for intensity control of a charged particle beam extracted from a synchrotron
US8378321B2 (en) * 2008-05-22 2013-02-19 Vladimir Balakin Charged particle cancer therapy and patient positioning method and apparatus
US9044600B2 (en) * 2008-05-22 2015-06-02 Vladimir Balakin Proton tomography apparatus and method of operation therefor
US8624528B2 (en) * 2008-05-22 2014-01-07 Vladimir Balakin Method and apparatus coordinating synchrotron acceleration periods with patient respiration periods
US8642978B2 (en) 2008-05-22 2014-02-04 Vladimir Balakin Charged particle cancer therapy dose distribution method and apparatus
US8378311B2 (en) 2008-05-22 2013-02-19 Vladimir Balakin Synchrotron power cycling apparatus and method of use thereof
US9974978B2 (en) 2008-05-22 2018-05-22 W. Davis Lee Scintillation array apparatus and method of use thereof
US9056199B2 (en) 2008-05-22 2015-06-16 Vladimir Balakin Charged particle treatment, rapid patient positioning apparatus and method of use thereof
US9095040B2 (en) 2008-05-22 2015-07-28 Vladimir Balakin Charged particle beam acceleration and extraction method and apparatus used in conjunction with a charged particle cancer therapy system
US9737733B2 (en) 2008-05-22 2017-08-22 W. Davis Lee Charged particle state determination apparatus and method of use thereof
US8710462B2 (en) * 2008-05-22 2014-04-29 Vladimir Balakin Charged particle cancer therapy beam path control method and apparatus
US8309941B2 (en) * 2008-05-22 2012-11-13 Vladimir Balakin Charged particle cancer therapy and patient breath monitoring method and apparatus
US10070831B2 (en) 2008-05-22 2018-09-11 James P. Bennett Integrated cancer therapy—imaging apparatus and method of use thereof
US8373145B2 (en) * 2008-05-22 2013-02-12 Vladimir Balakin Charged particle cancer therapy system magnet control method and apparatus
US8089054B2 (en) 2008-05-22 2012-01-03 Vladimir Balakin Charged particle beam acceleration and extraction method and apparatus used in conjunction with a charged particle cancer therapy system
US8288742B2 (en) * 2008-05-22 2012-10-16 Vladimir Balakin Charged particle cancer therapy patient positioning method and apparatus
US8188688B2 (en) 2008-05-22 2012-05-29 Vladimir Balakin Magnetic field control method and apparatus used in conjunction with a charged particle cancer therapy system
US8373146B2 (en) * 2008-05-22 2013-02-12 Vladimir Balakin RF accelerator method and apparatus used in conjunction with a charged particle cancer therapy system
US8374314B2 (en) 2008-05-22 2013-02-12 Vladimir Balakin Synchronized X-ray / breathing method and apparatus used in conjunction with a charged particle cancer therapy system
US8569717B2 (en) * 2008-05-22 2013-10-29 Vladimir Balakin Intensity modulated three-dimensional radiation scanning method and apparatus
US8907309B2 (en) 2009-04-17 2014-12-09 Stephen L. Spotts Treatment delivery control system and method of operation thereof
US10092776B2 (en) 2008-05-22 2018-10-09 Susan L. Michaud Integrated translation/rotation charged particle imaging/treatment apparatus and method of use thereof
US8975600B2 (en) 2008-05-22 2015-03-10 Vladimir Balakin Treatment delivery control system and method of operation thereof
US8718231B2 (en) 2008-05-22 2014-05-06 Vladimir Balakin X-ray tomography method and apparatus used in conjunction with a charged particle cancer therapy system
US10143854B2 (en) 2008-05-22 2018-12-04 Susan L. Michaud Dual rotation charged particle imaging / treatment apparatus and method of use thereof
US10684380B2 (en) 2008-05-22 2020-06-16 W. Davis Lee Multiple scintillation detector array imaging apparatus and method of use thereof
US9937362B2 (en) 2008-05-22 2018-04-10 W. Davis Lee Dynamic energy control of a charged particle imaging/treatment apparatus and method of use thereof
US9682254B2 (en) 2008-05-22 2017-06-20 Vladimir Balakin Cancer surface searing apparatus and method of use thereof
US9981147B2 (en) 2008-05-22 2018-05-29 W. Davis Lee Ion beam extraction apparatus and method of use thereof
US7939809B2 (en) * 2008-05-22 2011-05-10 Vladimir Balakin Charged particle beam extraction method and apparatus used in conjunction with a charged particle cancer therapy system
US8519365B2 (en) * 2008-05-22 2013-08-27 Vladimir Balakin Charged particle cancer therapy imaging method and apparatus
US8598543B2 (en) * 2008-05-22 2013-12-03 Vladimir Balakin Multi-axis/multi-field charged particle cancer therapy method and apparatus
US8637833B2 (en) 2008-05-22 2014-01-28 Vladimir Balakin Synchrotron power supply apparatus and method of use thereof
US9177751B2 (en) 2008-05-22 2015-11-03 Vladimir Balakin Carbon ion beam injector apparatus and method of use thereof
US20090314960A1 (en) * 2008-05-22 2009-12-24 Vladimir Balakin Patient positioning method and apparatus used in conjunction with a charged particle cancer therapy system
US8436327B2 (en) * 2008-05-22 2013-05-07 Vladimir Balakin Multi-field charged particle cancer therapy method and apparatus
US9737734B2 (en) 2008-05-22 2017-08-22 Susan L. Michaud Charged particle translation slide control apparatus and method of use thereof
US9498649B2 (en) 2008-05-22 2016-11-22 Vladimir Balakin Charged particle cancer therapy patient constraint apparatus and method of use thereof
US9855444B2 (en) 2008-05-22 2018-01-02 Scott Penfold X-ray detector for proton transit detection apparatus and method of use thereof
US10029122B2 (en) 2008-05-22 2018-07-24 Susan L. Michaud Charged particle—patient motion control system apparatus and method of use thereof
US9155911B1 (en) 2008-05-22 2015-10-13 Vladimir Balakin Ion source method and apparatus used in conjunction with a charged particle cancer therapy system
US8178859B2 (en) * 2008-05-22 2012-05-15 Vladimir Balakin Proton beam positioning verification method and apparatus used in conjunction with a charged particle cancer therapy system
US8373143B2 (en) * 2008-05-22 2013-02-12 Vladimir Balakin Patient immobilization and repositioning method and apparatus used in conjunction with charged particle cancer therapy
US9744380B2 (en) 2008-05-22 2017-08-29 Susan L. Michaud Patient specific beam control assembly of a cancer therapy apparatus and method of use thereof
US9910166B2 (en) 2008-05-22 2018-03-06 Stephen L. Spotts Redundant charged particle state determination apparatus and method of use thereof
US10548551B2 (en) 2008-05-22 2020-02-04 W. Davis Lee Depth resolved scintillation detector array imaging apparatus and method of use thereof
US9168392B1 (en) 2008-05-22 2015-10-27 Vladimir Balakin Charged particle cancer therapy system X-ray apparatus and method of use thereof
US9782140B2 (en) 2008-05-22 2017-10-10 Susan L. Michaud Hybrid charged particle / X-ray-imaging / treatment apparatus and method of use thereof
US8129699B2 (en) 2008-05-22 2012-03-06 Vladimir Balakin Multi-field charged particle cancer therapy method and apparatus coordinated with patient respiration
US9737272B2 (en) 2008-05-22 2017-08-22 W. Davis Lee Charged particle cancer therapy beam state determination apparatus and method of use thereof
US9616252B2 (en) 2008-05-22 2017-04-11 Vladimir Balakin Multi-field cancer therapy apparatus and method of use thereof
US8969834B2 (en) 2008-05-22 2015-03-03 Vladimir Balakin Charged particle therapy patient constraint apparatus and method of use thereof
US8198607B2 (en) * 2008-05-22 2012-06-12 Vladimir Balakin Tandem accelerator method and apparatus used in conjunction with a charged particle cancer therapy system
US9579525B2 (en) 2008-05-22 2017-02-28 Vladimir Balakin Multi-axis charged particle cancer therapy method and apparatus
US8627822B2 (en) * 2008-07-14 2014-01-14 Vladimir Balakin Semi-vertical positioning method and apparatus used in conjunction with a charged particle cancer therapy system
US8229072B2 (en) * 2008-07-14 2012-07-24 Vladimir Balakin Elongated lifetime X-ray method and apparatus used in conjunction with a charged particle cancer therapy system
US8625739B2 (en) 2008-07-14 2014-01-07 Vladimir Balakin Charged particle cancer therapy x-ray method and apparatus
WO2010139719A2 (de) 2009-06-05 2010-12-09 Basf Se Biokatalytische herstellung von ambroxan
US10188877B2 (en) 2010-04-16 2019-01-29 W. Davis Lee Fiducial marker/cancer imaging and treatment apparatus and method of use thereof
US9737731B2 (en) 2010-04-16 2017-08-22 Vladimir Balakin Synchrotron energy control apparatus and method of use thereof
US10179250B2 (en) 2010-04-16 2019-01-15 Nick Ruebel Auto-updated and implemented radiation treatment plan apparatus and method of use thereof
US10638988B2 (en) 2010-04-16 2020-05-05 Scott Penfold Simultaneous/single patient position X-ray and proton imaging apparatus and method of use thereof
US10625097B2 (en) 2010-04-16 2020-04-21 Jillian Reno Semi-automated cancer therapy treatment apparatus and method of use thereof
US10376717B2 (en) 2010-04-16 2019-08-13 James P. Bennett Intervening object compensating automated radiation treatment plan development apparatus and method of use thereof
US10086214B2 (en) 2010-04-16 2018-10-02 Vladimir Balakin Integrated tomography—cancer treatment apparatus and method of use thereof
US10349906B2 (en) 2010-04-16 2019-07-16 James P. Bennett Multiplexed proton tomography imaging apparatus and method of use thereof
US10555710B2 (en) 2010-04-16 2020-02-11 James P. Bennett Simultaneous multi-axes imaging apparatus and method of use thereof
US10751551B2 (en) 2010-04-16 2020-08-25 James P. Bennett Integrated imaging-cancer treatment apparatus and method of use thereof
US10556126B2 (en) 2010-04-16 2020-02-11 Mark R. Amato Automated radiation treatment plan development apparatus and method of use thereof
US11648420B2 (en) 2010-04-16 2023-05-16 Vladimir Balakin Imaging assisted integrated tomography—cancer treatment apparatus and method of use thereof
US10589128B2 (en) 2010-04-16 2020-03-17 Susan L. Michaud Treatment beam path verification in a cancer therapy apparatus and method of use thereof
US10518109B2 (en) 2010-04-16 2019-12-31 Jillian Reno Transformable charged particle beam path cancer therapy apparatus and method of use thereof
US8963112B1 (en) 2011-05-25 2015-02-24 Vladimir Balakin Charged particle cancer therapy patient positioning method and apparatus
US8933651B2 (en) 2012-11-16 2015-01-13 Vladimir Balakin Charged particle accelerator magnet apparatus and method of use thereof
EP3310768B1 (de) * 2015-06-19 2020-04-15 Basf Se Herstellung von pantolacton
US9907981B2 (en) 2016-03-07 2018-03-06 Susan L. Michaud Charged particle translation slide control apparatus and method of use thereof
US10037863B2 (en) 2016-05-27 2018-07-31 Mark R. Amato Continuous ion beam kinetic energy dissipater apparatus and method of use thereof
US20210340518A1 (en) 2018-10-18 2021-11-04 Basf Se Method for the production of acrylic acid or salts thereof
EP3748009A1 (en) * 2019-06-07 2020-12-09 DSM IP Assets B.V. Synthesis of (r)-pantolactone acetate
CN110452861B (zh) * 2019-07-10 2021-02-09 杭州师范大学 一种基因重组工程菌及其在催化合成d-泛酰内酯中的应用

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5572182A (en) * 1978-11-28 1980-05-30 Sagami Chem Res Center Optical resolution of pantolactone
JPH0667320B2 (ja) * 1986-06-13 1994-08-31 三菱化成株式会社 Ｄ−パントラクトンの製造法
JPH0655156B2 (ja) * 1986-06-13 1994-07-27 三菱化成株式会社 Ｄｌ−パントラクトンの光学分割法
JP2844354B2 (ja) 1989-08-03 1999-01-06 富士薬品工業株式会社 Ｄ―パントラクトンの製造法
DE4005150A1 (de) 1990-02-17 1991-08-22 Hoechst Ag Verfahren zur enzymatischen racematspaltung von pantolacton
JP3011449B2 (ja) * 1990-10-05 2000-02-21 富士薬品工業株式会社 Ｄ―パントラクトン加水分解酵素およびその製造法
EP0507278A3 (en) 1991-04-02 1993-12-15 Hoechst Ag Immobilised biocatalyser, its preparation and use for ester synthesis in a column reactor
DE4126580A1 (de) 1991-08-12 1993-02-18 Degussa D-2,4-dihydroxy-3,3-dimethylbutansaeurenitril, seine herstellung und verwendung
EP0626467B1 (en) 1992-10-15 1997-05-21 Kawasaki Steel Corporation Method of continuously carburizing steel strip
AU1810197A (en) * 1995-09-13 1997-04-01 Fuji Yakuhin Kogyo Kabushiki Kaisha D-pantolactone hydrolase and gene encoding the same
WO2000028043A2 (en) * 1998-11-10 2000-05-18 Novozymes Biotech, Inc. Polypeptides having lactonohydrolase activity and nucleic acids encoding same
US6395529B1 (en) * 1998-11-10 2002-05-28 Novozymes Biotech, Inc. Polypeptides having lactonohydrolase activity and nucleic acids encoding same

Also Published As

Publication number Publication date
EE200200225A (et) 2003-06-16
CN1384880A (zh) 2002-12-11
AU782517B2 (en) 2005-08-04
US6998258B1 (en) 2006-02-14
WO2001032890A1 (de) 2001-05-10
NO20021931L (no) 2002-04-24
CZ20021449A3 (cs) 2002-10-16
MXPA02003417A (es) 2002-08-20
BR0015114A (pt) 2002-07-16
PL355487A1 (en) 2004-05-04
RU2002114044A (ru) 2004-03-27
NO20021931D0 (no) 2002-04-24
HUP0203704A3 (en) 2006-03-28
CA2389064A1 (en) 2001-05-10
EP1224296A1 (de) 2002-07-24
KR20020043254A (ko) 2002-06-08
IL148973A0 (en) 2002-11-10
JP2003530080A (ja) 2003-10-14
AU1141601A (en) 2001-05-14

Similar Documents

Publication Publication Date Title
HUP0203704A2 (hu) L-Pankolakton hidroláz és eljárás D-pantolakton előállítására
DE60033138D1 (de) Polypeptide mit galaktoseoxidaseaktivität und dafür kodierende nukleisäuren
CY1107811T1 (el) Τροποποιημενες μονοoξυγενασες κυτοχρωματος p450
HUP9701652A2 (hu) Eljárás L-aminosav előállítására fermentáció útján
IL142397A0 (en) Method for producing chiral carboxylic acids from nitriles with the assistance of a nitrilase or microorganisms which contain a gene for the nitrilase
DE68925002D1 (de) Verfahren zur Herstellung von optisch-aktiven alpha-substituierten organischen Säuren und Mikroorganismen und Enzyme, die dafür verwendet werden.
YU83101A (sh) Postupci i materijali za sinteze organskih proizvoda
ATE319818T1 (de) Polypeptide mit aminopeptidaseaktivität und für diese kodierende nukleinsäuren
DE69840230D1 (de) Polypeptide mit prolyldipeptidylaminopeptidase-aktivität und dafür kodierende nukleinsäuren
ATE450603T1 (de) Polypeptide mit verzweigungsenzym-aktivität und für diese kodierende nukleinsäuren
ATE349528T1 (de) Transkriptionsaktivator prtt aus dem pilz aspergillus niger verwendbar in verfahren zur herstellung von polypeptiden
HUP9904513A2 (hu) Eljárás 2-hidroxi-4-metiltio-vajsav előállítására nitriláz alkalmazásával
AU7489098A (en) Polypeptides having aminopeptidase activity and nucleic acids encoding same
HUP0300155A2 (en) Nitrilase from phodococcus rhodochrous ncimb 11216
EP1757684A3 (en) A 2,6-beta-D-fructan hydrolase enzyme and processes for using the enzyme
ATE439430T1 (de) Mutanten für die herstellung von d-aminosäuren
WO2000028043A3 (en) Polypeptides having lactonohydrolase activity and nucleic acids encoding same
DE50110723D1 (de) Isolierte luziferasen sowie deren verwendung
DE60038281D1 (de) Verfahren zur herstellung von optisch aktiven pyridinethanol-derivaten
HUP0002022A2 (hu) Eljárás L-aminosavak fermentációs előállítására és az accDA-gént kódoló nukleotidszekvenciák
WO2002018560A3 (de) Butinol i esterase
IL157937A0 (en) D-hydantoinase, nucleic acid encoding the same, expression vectors including said nucleic acid and host cells expressing the same
WO2003060092A3 (en) Modified fatty acid hydroxylase protein and genes
ATE465268T1 (de) Verfahren zur mikrobiologischen isomerisierung von alpha-hydroxycarbonsäuren
AU7645400A (en) Polypeptides having glucanotransferase activity and nucleic acids encoding same

Legal Events

Date Code Title Description
FD9A Lapse of provisional protection due to non-payment of fees