ATE349528T1 - Transkriptionsaktivator prtt aus dem pilz aspergillus niger verwendbar in verfahren zur herstellung von polypeptiden - Google Patents

Transkriptionsaktivator prtt aus dem pilz aspergillus niger verwendbar in verfahren zur herstellung von polypeptiden

Info

Publication number
ATE349528T1
ATE349528T1 AT99945966T AT99945966T ATE349528T1 AT E349528 T1 ATE349528 T1 AT E349528T1 AT 99945966 T AT99945966 T AT 99945966T AT 99945966 T AT99945966 T AT 99945966T AT E349528 T1 ATE349528 T1 AT E349528T1
Authority
AT
Austria
Prior art keywords
polypeptides
prtt
usable
aspergillus niger
transcription activator
Prior art date
Application number
AT99945966T
Other languages
English (en)
Inventor
Carsten Hjort
Den Hondel Cees A M J J Van
Peter J Punt
Frank H J Schuren
Original Assignee
Novozymes As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novozymes As filed Critical Novozymes As
Application granted granted Critical
Publication of ATE349528T1 publication Critical patent/ATE349528T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/37—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from fungi
    • C07K14/38—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from fungi from Aspergillus
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/14—Fungi; Culture media therefor
    • C12N1/145—Fungal isolates
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/80—Vectors or expression systems specially adapted for eukaryotic hosts for fungi
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00—Microorganisms ; Processes using microorganisms
    • C12R2001/645—Fungi ; Processes using fungi
    • C12R2001/66—Aspergillus
    • C12R2001/685—Aspergillus niger

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Biotechnology (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Mycology (AREA)
  • Biomedical Technology (AREA)
  • Microbiology (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Botany (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Virology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Physics & Mathematics (AREA)
  • Plant Pathology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
AT99945966T 1998-10-05 1999-10-05 Transkriptionsaktivator prtt aus dem pilz aspergillus niger verwendbar in verfahren zur herstellung von polypeptiden ATE349528T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DKPA199801258 1998-10-05

Publications (1)

Publication Number Publication Date
ATE349528T1 true ATE349528T1 (de) 2007-01-15

Family

ID=8102827

Family Applications (1)

Application Number Title Priority Date Filing Date
AT99945966T ATE349528T1 (de) 1998-10-05 1999-10-05 Transkriptionsaktivator prtt aus dem pilz aspergillus niger verwendbar in verfahren zur herstellung von polypeptiden

Country Status (8)

Country Link
EP (2) EP1783223A1 (de)
JP (1) JP4563585B2 (de)
CN (1) CN1329667B (de)
AT (1) ATE349528T1 (de)
AU (1) AU5850999A (de)
DE (1) DE69934596T2 (de)
DK (1) DK1117798T3 (de)
WO (1) WO2000020596A1 (de)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK1266011T3 (da) * 2000-03-14 2010-07-26 Novozymes As Svampetranskriptionsaktivator, der er anvendelig i fremgangsmåder til fremstilling af polypeptider
CA2422730A1 (en) 2000-09-19 2002-03-28 Microbia, Inc. Modulation of secondary metabolite production by zinc binuclear cluster proteins
US7303877B2 (en) 2003-03-31 2007-12-04 Novozymes, Inc. Methods for producing biological substances in enzyme-deficient mutants of Aspergillus
EP1799827A2 (de) 2004-10-12 2007-06-27 DSMIP Assets B.V. Bei verfahren zur herstellung eines polypeptids geeignete transkriptionsaktivatoren aus pilzen
CN101454455A (zh) 2005-11-29 2009-06-10 帝斯曼知识产权资产管理有限公司 在基因表达中有用的转录激活因子的dna结合位点
EP2102240A2 (de) * 2007-01-05 2009-09-23 Novozymes A/S Überexpression des chaperon-bips in einem heterokaryon
WO2009058661A1 (en) * 2007-10-31 2009-05-07 Danisco Us Inc., Genencor Division Use and production of citrate-stable neutral metalloproteases
CN101182352B (zh) * 2007-11-21 2010-06-09 中国科学院微生物研究所 一种转录激活因子及其编码基因与应用
CN102597241B (zh) 2009-07-22 2015-09-02 帝斯曼知识产权资产管理有限公司 用于生产感兴趣的化合物的经改进的宿主细胞
DK3327112T3 (en) 2012-07-19 2020-05-04 Dsm Ip Assets Bv Agse-deficient stamme
KR20160035587A (ko) 2013-07-10 2016-03-31 노파르티스 아게 복수개의 프로테아제 결핍 사상형 진균 세포들 및 그의 이용방법
WO2016012468A1 (en) 2014-07-21 2016-01-28 Novartis Ag Production of glycoproteins with mammalian-like n-glycans in filamentous fungi
WO2016110453A1 (en) 2015-01-06 2016-07-14 Dsm Ip Assets B.V. A crispr-cas system for a filamentous fungal host cell
FR3046180B1 (fr) * 2015-12-28 2018-09-21 IFP Energies Nouvelles Souches mutantes de trichoderma reesei
US20200063166A1 (en) 2017-03-13 2020-02-27 Dsm Ip Assets B.V. Zinc binuclear cluster transcriptional regulator-deficient strain
BR112020025589A2 (pt) 2018-06-19 2021-03-23 Dsm Ip Assets B.V. variantes de enzima lipolítica
AU2021207258A1 (en) 2020-01-14 2022-08-04 The Protein Brewery B.V. Expression of ovalbumin and its natural variants
WO2023222614A1 (en) 2022-05-16 2023-11-23 Dsm Ip Assets B.V. Lipolytic enzyme variants
WO2023242273A1 (en) 2022-06-14 2023-12-21 Newmilkbuzz B.V. Expression of milk caseins in filamentous fungi
WO2024110509A1 (en) 2022-11-22 2024-05-30 Newmilkbuzz B.V Improved casein secretion by non-mammalian host cells
WO2024133849A1 (en) 2022-12-22 2024-06-27 The Protein Brewery B.V. Ovalbumin fermentation

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE248925T1 (de) * 1988-01-05 2003-09-15 Roche Diagnostics Gmbh Verfahren zur herstellung von proteinen oder proteinhaltigen genprodukten
EP0770139B1 (de) * 1994-06-17 2003-12-10 Novozymes A/S EIN PILZ, IN DEM DAS areA-GEN VERÄNDERT IST, UND EIN areA-GEN AUS ASPERGILLUS ORYZAE
AU7112796A (en) * 1995-09-27 1997-04-17 Chiron Corporation Method of making a protease deficient host
WO1997035956A1 (en) * 1996-03-27 1997-10-02 Novo Nordisk A/S Alkaline protease deficient filamentous fungi

Also Published As

Publication number Publication date
EP1783223A1 (de) 2007-05-09
DK1117798T3 (da) 2007-04-10
JP4563585B2 (ja) 2010-10-13
EP1117798B1 (de) 2006-12-27
DE69934596D1 (de) 2007-02-08
CN1329667A (zh) 2002-01-02
AU5850999A (en) 2000-04-26
DE69934596T2 (de) 2007-10-04
JP2002526112A (ja) 2002-08-20
EP1117798A1 (de) 2001-07-25
WO2000020596A1 (en) 2000-04-13
CN1329667B (zh) 2014-05-28

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