ATE349528T1 - Transkriptionsaktivator prtt aus dem pilz aspergillus niger verwendbar in verfahren zur herstellung von polypeptiden - Google Patents

Transkriptionsaktivator prtt aus dem pilz aspergillus niger verwendbar in verfahren zur herstellung von polypeptiden

Info

Publication number
ATE349528T1
ATE349528T1 AT99945966T AT99945966T ATE349528T1 AT E349528 T1 ATE349528 T1 AT E349528T1 AT 99945966 T AT99945966 T AT 99945966T AT 99945966 T AT99945966 T AT 99945966T AT E349528 T1 ATE349528 T1 AT E349528T1
Authority
AT
Austria
Prior art keywords
polypeptides
prtt
usable
aspergillus niger
transcription activator
Prior art date
Application number
AT99945966T
Other languages
English (en)
Inventor
Carsten Hjort
Den Hondel Cees A M J J Van
Peter J Punt
Frank H J Schuren
Original Assignee
Novozymes As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novozymes As filed Critical Novozymes As
Application granted granted Critical
Publication of ATE349528T1 publication Critical patent/ATE349528T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/37—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from fungi
    • C07K14/38—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from fungi from Aspergillus
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/14—Fungi; Culture media therefor
    • C12N1/145—Fungi isolates
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/80—Vectors or expression systems specially adapted for eukaryotic hosts for fungi
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00—Microorganisms ; Processes using microorganisms
    • C12R2001/645—Fungi ; Processes using fungi
    • C12R2001/66—Aspergillus
    • C12R2001/685—Aspergillus niger

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Biotechnology (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Mycology (AREA)
  • Biomedical Technology (AREA)
  • Microbiology (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Botany (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Virology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Physics & Mathematics (AREA)
  • Plant Pathology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
AT99945966T 1998-10-05 1999-10-05 Transkriptionsaktivator prtt aus dem pilz aspergillus niger verwendbar in verfahren zur herstellung von polypeptiden ATE349528T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DKPA199801258 1998-10-05

Publications (1)

Publication Number Publication Date
ATE349528T1 true ATE349528T1 (de) 2007-01-15

Family

ID=8102827

Family Applications (1)

Application Number Title Priority Date Filing Date
AT99945966T ATE349528T1 (de) 1998-10-05 1999-10-05 Transkriptionsaktivator prtt aus dem pilz aspergillus niger verwendbar in verfahren zur herstellung von polypeptiden

Country Status (8)

Country Link
EP (2) EP1117798B1 (de)
JP (1) JP4563585B2 (de)
CN (1) CN1329667B (de)
AT (1) ATE349528T1 (de)
AU (1) AU5850999A (de)
DE (1) DE69934596T2 (de)
DK (1) DK1117798T3 (de)
WO (1) WO2000020596A1 (de)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE60142226D1 (de) * 2000-03-14 2010-07-08 Novozymes As Pilz transkriptionsaktivator zur verwendung in verfahren zur herstellung von polypeptiden
CA2422730A1 (en) 2000-09-19 2002-03-28 Microbia, Inc. Modulation of secondary metabolite production by zinc binuclear cluster proteins
WO2004090155A2 (en) 2003-03-31 2004-10-21 Novozymes Inc. Methods for producing biological substances in enzyme-deficient mutants of aspergillus niger
CN101094919B (zh) 2004-10-12 2014-09-03 帝斯曼知识产权资产管理有限公司 在生产多肽的方法中有用的真菌转录活化因子
CN101454455A (zh) * 2005-11-29 2009-06-10 帝斯曼知识产权资产管理有限公司 在基因表达中有用的转录激活因子的dna结合位点
US20100062491A1 (en) * 2007-01-05 2010-03-11 Novozymes A/S Overexpression of the Chaperone BIP in a Heterokaryon
KR20100075986A (ko) * 2007-10-31 2010-07-05 다니스코 유에스 인크. 시트레이트-안정성 중성 메탈로프로테아제의 제조 및 용도
CN101182352B (zh) * 2007-11-21 2010-06-09 中国科学院微生物研究所 一种转录激活因子及其编码基因与应用
AU2010275672A1 (en) 2009-07-22 2012-02-02 Dsm Ip Assets B.V. Improved host cell for the production of a compound of interest
CN105308171B (zh) 2012-07-19 2019-03-08 帝斯曼知识产权资产管理有限公司 Agse缺陷菌株
KR20160035587A (ko) 2013-07-10 2016-03-31 노파르티스 아게 복수개의 프로테아제 결핍 사상형 진균 세포들 및 그의 이용방법
CN108064266A (zh) 2014-07-21 2018-05-22 格利科斯芬兰公司 在丝状真菌中具有哺乳动物样n-聚糖的糖蛋白的制备
DK3242950T3 (da) 2015-01-06 2021-12-20 Dsm Ip Assets Bv Crispr-cas-system til en trådformet svampeværtscelle
FR3046180B1 (fr) * 2015-12-28 2018-09-21 IFP Energies Nouvelles Souches mutantes de trichoderma reesei
US20200063166A1 (en) 2017-03-13 2020-02-27 Dsm Ip Assets B.V. Zinc binuclear cluster transcriptional regulator-deficient strain
WO2019243312A1 (en) 2018-06-19 2019-12-26 Dsm Ip Assets B.V. Lipolytic enzyme variants
US20230212634A1 (en) 2020-01-14 2023-07-06 The Protein Brewery B.V. Expression of Ovalbumin and its Natural Variants
EP4525626A1 (de) 2022-05-16 2025-03-26 DSM IP Assets B.V. Varianten eines lipolytischen enzyms
WO2023242273A1 (en) 2022-06-14 2023-12-21 Newmilkbuzz B.V. Expression of milk caseins in filamentous fungi
WO2024110509A1 (en) 2022-11-22 2024-05-30 Newmilkbuzz B.V Improved casein secretion by non-mammalian host cells
WO2024133849A1 (en) 2022-12-22 2024-06-27 The Protein Brewery B.V. Ovalbumin fermentation
WO2025230415A1 (en) 2024-04-30 2025-11-06 Ginkgo Bioworks Netherlands B.V. Host cells expressing optb protein variants and uses thereof

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0327797B1 (de) * 1988-01-05 2003-09-03 Roche Diagnostics GmbH Verfahren zur Herstellung von Proteinen oder proteinhaltigen Genprodukten
EP0770139B1 (de) * 1994-06-17 2003-12-10 Novozymes A/S EIN PILZ, IN DEM DAS areA-GEN VERÄNDERT IST, UND EIN areA-GEN AUS ASPERGILLUS ORYZAE
WO1997012045A1 (en) * 1995-09-27 1997-04-03 Chiron Corporation Method of making a protease deficient host
AU2152897A (en) * 1996-03-27 1997-10-17 Novo Nordisk A/S Alkaline protease deficient filamentous fungi

Also Published As

Publication number Publication date
CN1329667A (zh) 2002-01-02
JP4563585B2 (ja) 2010-10-13
DE69934596D1 (de) 2007-02-08
AU5850999A (en) 2000-04-26
CN1329667B (zh) 2014-05-28
DK1117798T3 (da) 2007-04-10
EP1783223A1 (de) 2007-05-09
WO2000020596A1 (en) 2000-04-13
EP1117798B1 (de) 2006-12-27
JP2002526112A (ja) 2002-08-20
DE69934596T2 (de) 2007-10-04
EP1117798A1 (de) 2001-07-25

Similar Documents

Publication Publication Date Title
ATE349528T1 (de) Transkriptionsaktivator prtt aus dem pilz aspergillus niger verwendbar in verfahren zur herstellung von polypeptiden
ATE469223T1 (de) Pilz transkriptionsaktivator zur verwendung in verfahren zur herstellung von polypeptiden
ATE310090T1 (de) Gereinigte coprinus laccasen und nukleinsäuren welche dafür kodieren
WO2001029222A3 (en) Polypeptides having phospholipase b activity and nucleic acids encoding same
DE60033138D1 (de) Polypeptide mit galaktoseoxidaseaktivität und dafür kodierende nukleisäuren
CA2315274A1 (en) Polypeptides having aminopeptidase activity and nucleic acids encoding same
WO2003089598A3 (en) Polypeptides having xyloglucanase activity and nucleic acids encoding same
DE60223250D1 (de) Verfahren zur herstellung von alpha-hydroxysäure, glycolsäure und 2-hydroxyisobuttersäure aus dem entsprechenden alpha-hydroxynitril mittels nitrilase
DE69840230D1 (de) Polypeptide mit prolyldipeptidylaminopeptidase-aktivität und dafür kodierende nukleinsäuren
ATE409235T1 (de) Verfahren zur herstellung von ascorbinsäurezwischenprodukten in wirtszellen
DK1165759T3 (da) Polypeptider, der har forgrenende enzymaktivitet, og nukleinsyrer, der koder for samme
DE69708818D1 (de) Verfahren zur Herstellung von Salpetersäure.
DK0981631T3 (da) Polypeptider, som har aminopeptidase-aktivitet, og nukleinsyrer, som koder for samme
WO1997027276A3 (en) Nucleic acids encoding polypeptides having absidia lipase activity
ATE410515T1 (de) Gene, welche für flavon-synthasen kodieren
ATE299858T1 (de) Verfahren zur herstellung von diaminodiphenylmethan und seiner höheren homologen
ATE312169T1 (de) 5-aminolevulinsaure synthase aus aspergillus oryzae und dafuer kodierende nukleinsaeure
WO2000028043A3 (en) Polypeptides having lactonohydrolase activity and nucleic acids encoding same
DE502004006579D1 (de) L-carnitin dehydrogenasen, deren derivate und ein verfahren zur herstellung von substituierten (s)-alkanolen
DE69734644D1 (de) Carboxypeptidasen aus aspergillus oryzae und diese kodierende nukleinsäuren
DE58908648D1 (de) Verfahren zur Herstellung von AOX-armer, chlorfreier Salzsäure.
DE60038281D1 (de) Verfahren zur herstellung von optisch aktiven pyridinethanol-derivaten
DE60226931D1 (de) Verfahren zur Herstellung von Polyester, Verfahren zur Herstellung von substituierter alpha-Hydroxycarbonsäure und Clostridium beijerinckii-Stamm HICA432
DE60040592D1 (de) Verfahren zur herstellung von alpha-aminoketonen
AU1526099A (en) Polypeptides having 5-aminolevulinic acid synthase activity and nucleic acids encoding same

Legal Events

Date Code Title Description
RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties