DK1117798T3 - Fungal transskriptionel aktivator egnet ved fremgangsmåder til produktion af polypeptider - Google Patents
Fungal transskriptionel aktivator egnet ved fremgangsmåder til produktion af polypeptiderInfo
- Publication number
- DK1117798T3 DK1117798T3 DK99945966T DK99945966T DK1117798T3 DK 1117798 T3 DK1117798 T3 DK 1117798T3 DK 99945966 T DK99945966 T DK 99945966T DK 99945966 T DK99945966 T DK 99945966T DK 1117798 T3 DK1117798 T3 DK 1117798T3
- Authority
- DK
- Denmark
- Prior art keywords
- transcriptional activator
- polypeptides
- production methods
- polypeptide production
- nucleic acid
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/37—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from fungi
- C07K14/38—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from fungi from Aspergillus
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
- C12N1/14—Fungi; Culture media therefor
- C12N1/145—Fungal isolates
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/80—Vectors or expression systems specially adapted for eukaryotic hosts for fungi
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
- C12R2001/00—Microorganisms ; Processes using microorganisms
- C12R2001/645—Fungi ; Processes using fungi
- C12R2001/66—Aspergillus
- C12R2001/685—Aspergillus niger
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Genetics & Genomics (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Wood Science & Technology (AREA)
- Biotechnology (AREA)
- Zoology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biochemistry (AREA)
- Biomedical Technology (AREA)
- General Health & Medical Sciences (AREA)
- Mycology (AREA)
- General Engineering & Computer Science (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- Microbiology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Plant Pathology (AREA)
- Physics & Mathematics (AREA)
- Gastroenterology & Hepatology (AREA)
- Botany (AREA)
- Tropical Medicine & Parasitology (AREA)
- Virology (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Enzymes And Modification Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DKPA199801258 | 1998-10-05 | ||
PCT/DK1999/000524 WO2000020596A1 (en) | 1998-10-05 | 1999-10-05 | Fungal transcriptional activator useful in methods for producing polypeptides |
Publications (1)
Publication Number | Publication Date |
---|---|
DK1117798T3 true DK1117798T3 (da) | 2007-04-10 |
Family
ID=8102827
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK99945966T DK1117798T3 (da) | 1998-10-05 | 1999-10-05 | Fungal transskriptionel aktivator egnet ved fremgangsmåder til produktion af polypeptider |
Country Status (8)
Country | Link |
---|---|
EP (2) | EP1117798B1 (de) |
JP (1) | JP4563585B2 (de) |
CN (1) | CN1329667B (de) |
AT (1) | ATE349528T1 (de) |
AU (1) | AU5850999A (de) |
DE (1) | DE69934596T2 (de) |
DK (1) | DK1117798T3 (de) |
WO (1) | WO2000020596A1 (de) |
Families Citing this family (21)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2003526374A (ja) * | 2000-03-14 | 2003-09-09 | ノボザイムス アクティーゼルスカブ | ポリペプチドの生成方法において有用な菌類転写活性化因子 |
AU2001291114A1 (en) | 2000-09-19 | 2002-04-02 | Microbia, Inc. | Modulation of secondary metabolite production by zinc binuclear cluster proteins |
JP4638418B2 (ja) | 2003-03-31 | 2011-02-23 | ノボザイムス,インコーポレイティド | アスペルギラス・ニガーの酵素−欠失変異体における生物学的物質の生成方法 |
WO2006040312A2 (en) * | 2004-10-12 | 2006-04-20 | Dsm Ip Assets B.V. | Fungal transcriptional activators useful in methods for producing a polypeptide |
EP2458007A1 (de) | 2005-11-29 | 2012-05-30 | DSM IP Assets B.V. | DNA-Bindungsstelle eines transkriptionellen Aktivators zur Genexpression |
US20100062491A1 (en) * | 2007-01-05 | 2010-03-11 | Novozymes A/S | Overexpression of the Chaperone BIP in a Heterokaryon |
MX2010004372A (es) * | 2007-10-31 | 2010-05-20 | Danisco Us Inc | Uso y elaboracion de metaloproteasas neutras estables en citrato. |
CN101182352B (zh) * | 2007-11-21 | 2010-06-09 | 中国科学院微生物研究所 | 一种转录激活因子及其编码基因与应用 |
US8734782B2 (en) | 2009-07-22 | 2014-05-27 | Dsm Ip Assets B.V. | Host cell for the production of a compound of interest |
EP2875119B1 (de) | 2012-07-19 | 2017-12-20 | DSM IP Assets B.V. | Agse-armer stamm |
RU2016104064A (ru) | 2013-07-10 | 2017-08-15 | Новартис Аг | Клетки мицелиальных грибов с множественной недостаточностью протеаз и способы их использования |
US10513724B2 (en) | 2014-07-21 | 2019-12-24 | Glykos Finland Oy | Production of glycoproteins with mammalian-like N-glycans in filamentous fungi |
DK3242950T3 (da) | 2015-01-06 | 2021-12-20 | Dsm Ip Assets Bv | Crispr-cas-system til en trådformet svampeværtscelle |
FR3046180B1 (fr) * | 2015-12-28 | 2018-09-21 | IFP Energies Nouvelles | Souches mutantes de trichoderma reesei |
US20200063166A1 (en) | 2017-03-13 | 2020-02-27 | Dsm Ip Assets B.V. | Zinc binuclear cluster transcriptional regulator-deficient strain |
MX2020014191A (es) | 2018-06-19 | 2021-03-09 | Dsm Ip Assets Bv | Variantes de enzimas lipoliticas. |
EP4090676A1 (de) | 2020-01-14 | 2022-11-23 | The Protein Brewery B.V. | Expression von ovalbumin und seinen natürlichen varianten |
WO2023222614A1 (en) | 2022-05-16 | 2023-11-23 | Dsm Ip Assets B.V. | Lipolytic enzyme variants |
WO2023242273A1 (en) | 2022-06-14 | 2023-12-21 | Newmilkbuzz B.V. | Expression of milk caseins in filamentous fungi |
WO2024110509A1 (en) | 2022-11-22 | 2024-05-30 | Newmilkbuzz B.V | Improved casein secretion by non-mammalian host cells |
WO2024133849A1 (en) | 2022-12-22 | 2024-06-27 | The Protein Brewery B.V. | Ovalbumin fermentation |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0327797B1 (de) * | 1988-01-05 | 2003-09-03 | Roche Diagnostics GmbH | Verfahren zur Herstellung von Proteinen oder proteinhaltigen Genprodukten |
AU2733895A (en) * | 1994-06-17 | 1996-01-15 | Novo Nordisk A/S | A fungus wherein the area gene has been modified and an area gene from aspergillus oryzae |
AU7112796A (en) * | 1995-09-27 | 1997-04-17 | Chiron Corporation | Method of making a protease deficient host |
CN1120235C (zh) * | 1996-03-27 | 2003-09-03 | 诺沃奇梅兹有限公司 | 碱性蛋白酶缺陷型丝状真菌 |
-
1999
- 1999-10-05 DK DK99945966T patent/DK1117798T3/da active
- 1999-10-05 EP EP99945966A patent/EP1117798B1/de not_active Expired - Lifetime
- 1999-10-05 JP JP2000574691A patent/JP4563585B2/ja not_active Expired - Fee Related
- 1999-10-05 CN CN99814016.3A patent/CN1329667B/zh not_active Expired - Fee Related
- 1999-10-05 AU AU58509/99A patent/AU5850999A/en not_active Abandoned
- 1999-10-05 EP EP06126806A patent/EP1783223A1/de not_active Withdrawn
- 1999-10-05 DE DE69934596T patent/DE69934596T2/de not_active Expired - Lifetime
- 1999-10-05 WO PCT/DK1999/000524 patent/WO2000020596A1/en active IP Right Grant
- 1999-10-05 AT AT99945966T patent/ATE349528T1/de not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
AU5850999A (en) | 2000-04-26 |
JP4563585B2 (ja) | 2010-10-13 |
EP1117798B1 (de) | 2006-12-27 |
DE69934596D1 (de) | 2007-02-08 |
ATE349528T1 (de) | 2007-01-15 |
CN1329667A (zh) | 2002-01-02 |
DE69934596T2 (de) | 2007-10-04 |
EP1117798A1 (de) | 2001-07-25 |
CN1329667B (zh) | 2014-05-28 |
EP1783223A1 (de) | 2007-05-09 |
WO2000020596A1 (en) | 2000-04-13 |
JP2002526112A (ja) | 2002-08-20 |
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