DK1266011T3 - Svampetranskriptionsaktivator, der er anvendelig i fremgangsmåder til fremstilling af polypeptider - Google Patents

Svampetranskriptionsaktivator, der er anvendelig i fremgangsmåder til fremstilling af polypeptider

Info

Publication number
DK1266011T3
DK1266011T3 DK01915099.4T DK01915099T DK1266011T3 DK 1266011 T3 DK1266011 T3 DK 1266011T3 DK 01915099 T DK01915099 T DK 01915099T DK 1266011 T3 DK1266011 T3 DK 1266011T3
Authority
DK
Denmark
Prior art keywords
methods
polypeptides
transcription activator
producing polypeptides
nucleic acid
Prior art date
Application number
DK01915099.4T
Other languages
English (en)
Inventor
C Mjj Van Den Hondel
P J Punt
F H J Schuren
Carsten M Hjort
Tove Christensen
Original Assignee
Novozymes As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novozymes As filed Critical Novozymes As
Application granted granted Critical
Publication of DK1266011T3 publication Critical patent/DK1266011T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/37—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from fungi
    • C07K14/385—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from fungi from Penicillium
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/37—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from fungi
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/37—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from fungi
    • C07K14/38—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from fungi from Aspergillus

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Biophysics (AREA)
  • Mycology (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Peptides Or Proteins (AREA)
DK01915099.4T 2000-03-14 2001-03-14 Svampetranskriptionsaktivator, der er anvendelig i fremgangsmåder til fremstilling af polypeptider DK1266011T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DKPA200000406 2000-03-14
PCT/DK2001/000169 WO2001068864A1 (en) 2000-03-14 2001-03-14 Fungal transcriptional activator useful in methods for producing polypeptides

Publications (1)

Publication Number Publication Date
DK1266011T3 true DK1266011T3 (da) 2010-07-26

Family

ID=8159325

Family Applications (1)

Application Number Title Priority Date Filing Date
DK01915099.4T DK1266011T3 (da) 2000-03-14 2001-03-14 Svampetranskriptionsaktivator, der er anvendelig i fremgangsmåder til fremstilling af polypeptider

Country Status (8)

Country Link
EP (1) EP1266011B1 (da)
JP (1) JP2003526374A (da)
CN (2) CN102174535B (da)
AT (1) ATE469223T1 (da)
AU (1) AU2001242299A1 (da)
DE (1) DE60142226D1 (da)
DK (1) DK1266011T3 (da)
WO (1) WO2001068864A1 (da)

Families Citing this family (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE602004022929D1 (de) 2003-03-31 2009-10-15 Novozymes Inc Verfahren zur produktion biologischer substanzen i
CN101094919B (zh) 2004-10-12 2014-09-03 帝斯曼知识产权资产管理有限公司 在生产多肽的方法中有用的真菌转录活化因子
US7888489B2 (en) 2005-01-24 2011-02-15 Dsm Ip Assets B.V. Method for producing a compound of interest in a filamentous fungal cell
WO2006097464A1 (en) 2005-03-16 2006-09-21 Novozymes A/S Recombinant expression of defensins in filamentous fungi
US7858360B2 (en) 2005-10-17 2010-12-28 Novozymes A/S Use of fungal mutants for expression of antibodies
EA014783B1 (ru) * 2005-11-29 2011-02-28 ДСМ АйПи АССЕТС Б.В. Связывающий днк-сайт активатора транскрипции, пригодный для экспрессии генов
EA015925B1 (ru) 2006-06-29 2011-12-30 ДСМ АйПи АССЕТС Б.В. Способ получения полипептидов
DK2147107T3 (da) 2007-05-09 2011-10-24 Novozymes As Fremgangsmåde til ekspressionskloning, som er egnet til selektion af bibliotekskloner, der producerer et polypeptid af interesse
CN101182352B (zh) * 2007-11-21 2010-06-09 中国科学院微生物研究所 一种转录激活因子及其编码基因与应用
WO2011009700A1 (en) 2009-07-22 2011-01-27 Dsm Ip Assets B.V. Improved host cell for the production of a compound of interest
CN101906393B (zh) * 2010-06-28 2012-07-25 江南大学 一种谷氨酰胺转胺酶编码基因阻断吸水链霉菌及其应用
CN103443268A (zh) 2011-01-20 2013-12-11 诺维信公司 植物过氧化物酶在丝状真菌中的表达
EP2527448A1 (en) 2011-05-23 2012-11-28 Novozymes A/S Simultaneous site-specific integrations of multiple gene-copies in filamentous fungi
EP2527432A1 (en) 2011-05-23 2012-11-28 Novozymes A/S Bi-directional cytosine deaminase-encoding selection marker
BR112014016587A2 (pt) 2012-01-05 2020-10-27 Novartis Ag células fúngicas filamentosas deficientes de protease e métodos de uso das mesmas
WO2013174927A1 (en) 2012-05-23 2013-11-28 Novartis International Pharmaceutical Limited Production of fucosylated glycoproteins
AU2013291936B2 (en) 2012-07-19 2019-01-17 Dsm Ip Assets B.V. AgsE-deficient strain
CA2916905A1 (en) 2013-07-10 2015-01-15 Novartis Ag Multiple proteases deficient filamentous fungal cells and methods of use thereof
CA2954974A1 (en) 2014-07-21 2016-01-28 Glykos Finland Oy Production of glycoproteins with mammalian-like n-glycans in filamentous fungi
WO2016110453A1 (en) 2015-01-06 2016-07-14 Dsm Ip Assets B.V. A crispr-cas system for a filamentous fungal host cell
JP6473339B2 (ja) * 2015-02-05 2019-02-20 本田技研工業株式会社 麹菌変異株及び形質転換体
DK3259364T3 (da) 2015-02-20 2020-09-07 Roal Oy Fremgangsmåder til styring af proteasefremstilling
EP3596199A1 (en) 2017-03-13 2020-01-22 DSM IP Assets B.V. Zinc binuclear cluster transcriptional regulator-deficient strain
WO2018167153A1 (en) 2017-03-17 2018-09-20 Novozymes A/S Improved filamentous fungal host cell
EP3809852A1 (en) 2018-06-19 2021-04-28 DSM IP Assets B.V. Lipolytic enzyme variants
US20230212634A1 (en) 2020-01-14 2023-07-06 The Protein Brewery B.V. Expression of Ovalbumin and its Natural Variants
WO2023222614A1 (en) 2022-05-16 2023-11-23 Dsm Ip Assets B.V. Lipolytic enzyme variants
WO2023242273A1 (en) 2022-06-14 2023-12-21 Newmilkbuzz B.V. Expression of milk caseins in filamentous fungi
WO2024110509A1 (en) 2022-11-22 2024-05-30 Newmilkbuzz B.V Improved casein secretion by non-mammalian host cells

Family Cites Families (14)

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Publication number Priority date Publication date Assignee Title
US4288627A (en) 1980-02-12 1981-09-08 Phillips Petroleum Company Oxidation of thiols employing cobalt molybdate/triethylamine catalyst
DK122686D0 (da) 1986-03-17 1986-03-17 Novo Industri As Fremstilling af proteiner
CA1333777C (en) 1988-07-01 1995-01-03 Randy M. Berka Aspartic proteinase deficient filamentous fungi
ES2208637T3 (es) 1992-04-15 2004-06-16 Novartis Ag Nueva proteasa fungica.
DK52293D0 (da) 1993-05-05 1993-05-05 Novo Nordisk As
DK76893D0 (da) 1993-06-28 1993-06-28 Novo Nordisk As
DE69523052T2 (de) 1994-06-03 2002-06-20 Novo Nordisk Biotech Inc Gereinigte myceliophthora laccasen und nukleinsäuren dafür kodierend
DK0770139T3 (da) * 1994-06-17 2004-04-13 Novozymes As En svamp, hvor areA-genet er blevet modificeret, samt et areA-gen fra aspergillus oryzae
ATE294871T1 (de) 1994-06-30 2005-05-15 Novozymes Biotech Inc Nicht-toxisches, nicht-toxigenes, nicht- pathogenes fusarium expressionssystem und darin zu verwendende promotoren und terminatoren
WO1997012045A1 (en) 1995-09-27 1997-04-03 Chiron Corporation Method of making a protease deficient host
CN1120235C (zh) 1996-03-27 2003-09-03 诺沃奇梅兹有限公司 碱性蛋白酶缺陷型丝状真菌
EP1616580B1 (en) 1996-07-05 2007-09-19 Novozymes A/S Alpha-amylase transcription factor
DK0956338T3 (da) 1996-09-19 2006-05-08 Novozymes As Værtsceller og fremgangsmåder til produktion af proteiner
EP1117798B1 (en) * 1998-10-05 2006-12-27 Novozymes A/S Fungal transcriptional activator prtt from aspergillus niger, useful in methods for producing polypeptides

Also Published As

Publication number Publication date
EP1266011B1 (en) 2010-05-26
WO2001068864A1 (en) 2001-09-20
DE60142226D1 (de) 2010-07-08
CN1425068A (zh) 2003-06-18
ATE469223T1 (de) 2010-06-15
EP1266011A1 (en) 2002-12-18
CN102174535B (zh) 2014-04-09
AU2001242299A1 (en) 2001-09-24
CN1425068B (zh) 2011-05-18
JP2003526374A (ja) 2003-09-09
CN102174535A (zh) 2011-09-07

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