AU7112796A - Method of making a protease deficient host - Google Patents

Method of making a protease deficient host

Info

Publication number
AU7112796A
AU7112796A AU71127/96A AU7112796A AU7112796A AU 7112796 A AU7112796 A AU 7112796A AU 71127/96 A AU71127/96 A AU 71127/96A AU 7112796 A AU7112796 A AU 7112796A AU 7112796 A AU7112796 A AU 7112796A
Authority
AU
Australia
Prior art keywords
making
deficient host
protease deficient
protease
host
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU71127/96A
Inventor
Robert J. Bishop
Michael A. Innis
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Novartis Vaccines and Diagnostics Inc
Original Assignee
Chiron Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Chiron Corp filed Critical Chiron Corp
Publication of AU7112796A publication Critical patent/AU7112796A/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/67—General methods for enhancing the expression
AU71127/96A 1995-09-27 1996-09-17 Method of making a protease deficient host Abandoned AU7112796A (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US436195P 1995-09-27 1995-09-27
US004361 1995-09-27
PCT/US1996/014947 WO1997012045A1 (en) 1995-09-27 1996-09-17 Method of making a protease deficient host

Publications (1)

Publication Number Publication Date
AU7112796A true AU7112796A (en) 1997-04-17

Family

ID=21710410

Family Applications (1)

Application Number Title Priority Date Filing Date
AU71127/96A Abandoned AU7112796A (en) 1995-09-27 1996-09-17 Method of making a protease deficient host

Country Status (2)

Country Link
AU (1) AU7112796A (en)
WO (1) WO1997012045A1 (en)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5776730A (en) * 1995-12-15 1998-07-07 University Of Hawaii Neurospora hosts for the production of recombinant proteins, and methods for producing same
WO1998054331A2 (en) * 1997-05-27 1998-12-03 National Research Council Of Canada High level expression of glycosyltransferases
GB9713412D0 (en) * 1997-06-26 1997-08-27 Delta Biotechnology Ltd Improved protein expression strains
US6806062B1 (en) 1998-10-05 2004-10-19 Novozymes A/S Fungal transcriptional activator useful in methods for producing polypeptides
DK1117798T3 (en) * 1998-10-05 2007-04-10 Novozymes As Fungal transcriptional activator suitable for polypeptide production methods
DE60142226D1 (en) 2000-03-14 2010-07-08 Novozymes As MUSHROOM TRANSCRIPTION ACTIVATOR FOR USE IN PROCESSES FOR THE PREPARATION OF POLYPEPTIDES
EP1930428B1 (en) * 2005-08-03 2010-12-01 Asahi Glass Company, Limited transformed yeast host cells AND METHOD OF PRODUCING FOREIGN PROTEIN
AU2013207165B2 (en) 2012-01-05 2018-10-04 Glykos Finland Oy Protease deficient filamentous fungal cells and methods of use thereof
WO2013174927A1 (en) 2012-05-23 2013-11-28 Novartis International Pharmaceutical Limited Production of fucosylated glycoproteins
EP3019602B1 (en) 2013-07-10 2018-09-05 Glykos Finland Oy Multiple proteases deficient filamentous fungal cells and methods of use thereof
CA2954974A1 (en) 2014-07-21 2016-01-28 Glykos Finland Oy Production of glycoproteins with mammalian-like n-glycans in filamentous fungi

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5143846A (en) * 1988-03-17 1992-09-01 The General Hospital Corporation Protease deficient bacterial hosts
AU614121B2 (en) * 1988-05-04 1991-08-22 Novartis Ag Improvements in the production of polypeptides
EP0574374A1 (en) * 1992-05-29 1993-12-15 Josef Brosowitsch Refuse collecting container with a variable compartment volume

Also Published As

Publication number Publication date
WO1997012045A1 (en) 1997-04-03

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