EE200100232A - Meetod kiraalsete karboksüülhapete saamiseks nitriilidest nitrilaasi või mikroorganismide abil, missisaldavad ühte geeni nitrilaasi jaoks - Google Patents

Meetod kiraalsete karboksüülhapete saamiseks nitriilidest nitrilaasi või mikroorganismide abil, missisaldavad ühte geeni nitrilaasi jaoks

Info

Publication number
EE200100232A
EE200100232A EEP200100232A EEP200100232A EE200100232A EE 200100232 A EE200100232 A EE 200100232A EE P200100232 A EEP200100232 A EE P200100232A EE P200100232 A EEP200100232 A EE P200100232A EE 200100232 A EE200100232 A EE 200100232A
Authority
EE
Estonia
Prior art keywords
nucleic acid
nitrilase
acid sequences
carboxylic acids
nitriles
Prior art date
Application number
EEP200100232A
Other languages
English (en)
Inventor
Ress-L�schke Marion
Friedrich Thomas
Hauer Bernhard
Mattes Ralf
Engels Dirk
Original Assignee
Basf Aktiengesellschaft
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Basf Aktiengesellschaft filed Critical Basf Aktiengesellschaft
Publication of EE200100232A publication Critical patent/EE200100232A/et
Publication of EE05008B1 publication Critical patent/EE05008B1/et

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/11DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/52Genes encoding for enzymes or proenzymes
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H21/00Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14Hydrolases (3)
    • C12N9/78Hydrolases (3) acting on carbon to nitrogen bonds other than peptide bonds (3.5)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P41/00Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture
    • C12P41/006Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture by reactions involving C-N bonds, e.g. nitriles, amides, hydantoins, carbamates, lactames, transamination reactions, or keto group formation from racemic mixtures
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00Preparation of oxygen-containing organic compounds
    • C12P7/40Preparation of oxygen-containing organic compounds containing a carboxyl group including Peroxycarboxylic acids
    • C12P7/42Hydroxy-carboxylic acids

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Biomedical Technology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • Analytical Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Plant Pathology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Enzymes And Modification Thereof (AREA)
EEP200100232A 1998-10-19 1999-10-13 Meetod kiraalsete karboksüülhapete saamiseks nitriilidest nitrilaasi v?i mikroorganismide abil, missisaldavad ühte geeni nitrilaasi jaoks EE05008B1 (et)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19848129A DE19848129A1 (de) 1998-10-19 1998-10-19 Verfahren zur Herstellung chiraler Carbonsäuren aus Nitrilen mit Hilfe einer Nitrilase oder Mikroorganismen, die ein Gen für die Nitrilase enthalten
PCT/EP1999/007679 WO2000023577A1 (de) 1998-10-19 1999-10-13 Verfahren zur herstellung chiraler carbonsäuren aus nitrilen mit hilfe einer nitrilase oder mikroorganismen, die ein gen für die nitrilase enthalten

Publications (2)

Publication Number Publication Date
EE200100232A true EE200100232A (et) 2002-08-15
EE05008B1 EE05008B1 (et) 2008-04-15

Family

ID=7884933

Family Applications (1)

Application Number Title Priority Date Filing Date
EEP200100232A EE05008B1 (et) 1998-10-19 1999-10-13 Meetod kiraalsete karboksüülhapete saamiseks nitriilidest nitrilaasi v?i mikroorganismide abil, missisaldavad ühte geeni nitrilaasi jaoks

Country Status (21)

Country Link
US (1) US6869783B1 (et)
EP (1) EP1123386B1 (et)
JP (1) JP4489298B2 (et)
KR (1) KR100715744B1 (et)
CN (1) CN100422319C (et)
AT (1) ATE349517T1 (et)
AU (1) AU765480B2 (et)
BR (1) BR9914629A (et)
CA (1) CA2347521C (et)
CZ (1) CZ302494B6 (et)
DE (2) DE19848129A1 (et)
DK (1) DK1123386T3 (et)
EE (1) EE05008B1 (et)
ES (1) ES2280125T3 (et)
HU (1) HU228092B1 (et)
ID (1) ID29136A (et)
IL (2) IL142397A0 (et)
NO (1) NO327857B1 (et)
PT (1) PT1123386E (et)
WO (1) WO2000023577A1 (et)
ZA (1) ZA200104066B (et)

Families Citing this family (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19848129A1 (de) * 1998-10-19 2000-04-20 Basf Ag Verfahren zur Herstellung chiraler Carbonsäuren aus Nitrilen mit Hilfe einer Nitrilase oder Mikroorganismen, die ein Gen für die Nitrilase enthalten
US20040002147A1 (en) * 1999-12-29 2004-01-01 Desantis Grace Nitrilases
DE10010149A1 (de) * 2000-03-03 2001-09-06 Basf Ag Nitrilase aus Rhodococcus rhodochrous NCIMB 11216
US6455730B1 (en) 2000-08-04 2002-09-24 E. I. Du Pont De Nemours & Company Preparation of dicarboxylic acid monoesters from cyanocarboxylic acid esters
US6562603B2 (en) * 2000-08-04 2003-05-13 E. I. Du Pont De Nemours And Company 3-hydroxycarboxylic acid production and use in branched polymers
AU2001296653A1 (en) * 2000-10-04 2002-04-15 Maxygen, Inc. Enantioselective production of amino carboxylic acids
FR2822460B1 (fr) * 2001-03-26 2005-04-29 Rhodia Chimie Sa Procede de preparation enantioselectif d'acides carboxyliques optiquement actifs par hydrolyse enzymatique de nitriles
EP1578910A4 (en) 2001-06-21 2008-06-04 Verenium Corp NITRILASES
ITMI20011826A1 (it) * 2001-08-30 2003-03-02 Istituto Biochimico Italiano Microorganismo dotato di attivita' nitrile-idratasica/amidasica enantioselettiva e regioselettiva
DK1570060T3 (da) 2002-12-02 2007-11-05 Basf Ag L-rhamnoseinducerbare ekspressionssystemer
AU2003296731B2 (en) * 2003-01-08 2009-07-09 Basf Aktiengesellschaft Methods for preserving and/or storing cells having a nitrilase or nitrile hydratase activity
AT412092B (de) * 2003-02-27 2004-09-27 Dsm Fine Chem Austria Gmbh Verfahren zur herstellung chiraler alpha-hydroxycarbonsäuren durch enzymatische hydrolyse von chiralen cyanhydrinen
CN100445375C (zh) * 2003-02-27 2008-12-24 巴斯福股份公司 经修饰的腈水解酶及它们在产生羧酸的方法中的用途
CN102796770B (zh) * 2004-12-22 2014-06-04 纳幕尔杜邦公司 乙醇酸的酶促生产
US20100267100A1 (en) * 2007-03-21 2010-10-21 Ling Hua Enzymatic synthesis of optically pure beta-hydroxy carboxylic acids and their derivatives
US20090004720A1 (en) * 2007-06-26 2009-01-01 Ling Hua Smart Biocatalysts For Organic Synthesis
EP2338987A1 (en) 2009-11-16 2011-06-29 ZYRUS Beteiligungsgesellschaft mbH & Co. Patente I KG Whole cell biocatalyst
JP2013162746A (ja) * 2010-05-24 2013-08-22 Mitsui Chemicals Inc アミド化合物の製造方法
EP2643467A1 (de) 2010-11-24 2013-10-02 Basf Se Verfahren zur herstellung n-heterozyklischer optisch aktiver alkohole
KR101223664B1 (ko) * 2011-01-26 2013-01-17 재단법인 경북해양바이오산업연구원 나이트릴레이즈 rmn1을 이용한 카르복실산의 제조방법
KR101223663B1 (ko) * 2011-01-26 2013-01-21 재단법인 경북해양바이오산업연구원 나이트릴레이즈 vmn1을 이용한 카르복실산의 제조방법
KR101223666B1 (ko) * 2011-01-26 2013-01-17 재단법인 경북해양바이오산업연구원 나이트릴레이즈 orn을 이용한 카르복실산의 제조방법
KR101223665B1 (ko) * 2011-01-26 2013-01-17 재단법인 경북해양바이오산업연구원 나이트릴레이즈 rmn2을 이용한 카르복실산의 제조방법
AU2021272383A1 (en) 2020-05-15 2022-12-08 Basf Se Improved method for the production of isoprenoids
WO2023105080A1 (en) 2021-12-10 2023-06-15 Basf Se Synthesis of glufosinate using a hydantoinase-based process
WO2023105079A1 (en) 2021-12-10 2023-06-15 Basf Se Enzymatic decarbamoylation of glufosinate derivatives
AR127936A1 (es) 2021-12-10 2024-03-13 Basf Se Actividad herbicida de alquilfosfinatos

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE68926922T2 (de) 1988-03-08 1996-12-19 Japan Energy Corp Verfahren zur Herstellung von L-alpha-Aminosäuren
US5283193A (en) 1988-06-27 1994-02-01 Asahi Kasei Kogyo K.K. Process for producing optically active α-substituted organic acid and microorganism and enzyme used therefor
DK314989A (da) * 1988-06-27 1989-12-28 Asahi Chemical Ind Fremgangsmaade til fremstilling af optisk aktive alfa-substituerede organiske syrer, samt mikroorganismer og enzymer anvendelige ved fremgangsmaaden
JPH0219577A (ja) 1988-07-04 1990-01-23 Nippon Saafuakutanto Kogyo Kk 反応染料用均染剤組成物
EP0449648B1 (en) * 1990-03-30 1999-05-12 Nitto Chemical Industry Co., Ltd. Process for producing R(-)-mandelic acid and derivatives thereof
JP2974737B2 (ja) 1990-08-16 1999-11-10 三菱レイヨン株式会社 光学活性乳酸の製造法
DK0549710T3 (da) 1990-09-20 1996-03-18 Du Pont Fremgangsmåde til fremstilling af enantiomere 2-alkansyrer
JP2676568B2 (ja) 1991-06-26 1997-11-17 日東化学工業株式会社 R(−)−マンデル酸およびその誘導体の製造法
JP3093056B2 (ja) * 1992-11-17 2000-10-03 三菱レイヨン株式会社 ニトリラーゼ活性を有するポリペプチドをコードする遺伝子dnaを含有する形質転換体による有機酸の製造法
JP3218133B2 (ja) 1993-02-03 2001-10-15 三菱レイヨン株式会社 フェニル基を有する光学活性α−ヒドロキシカルボン酸の製造法
JP2720140B2 (ja) 1993-02-03 1998-02-25 日東化学工業株式会社 フェニル基を有する光学活性α−ヒドロキシカルボン酸の製造法
JP3354688B2 (ja) 1994-01-28 2002-12-09 三菱レイヨン株式会社 微生物によるα−ヒドロキシ酸またはα−ヒドロキシアミドの製造法
JP3154633B2 (ja) 1994-12-28 2001-04-09 三菱レイヨン株式会社 ニトリラーゼ遺伝子発現のための調節因子およびその遺伝子
DE69737696T2 (de) 1996-02-29 2008-01-10 Nippon Soda Co. Ltd. Prozess für die herstellung von alpha-hydroxysäuren mit hilfe eines mikroorganismus und eines neuen mikroorganismus.
DE19848129A1 (de) * 1998-10-19 2000-04-20 Basf Ag Verfahren zur Herstellung chiraler Carbonsäuren aus Nitrilen mit Hilfe einer Nitrilase oder Mikroorganismen, die ein Gen für die Nitrilase enthalten

Also Published As

Publication number Publication date
ATE349517T1 (de) 2007-01-15
CZ20011382A3 (cs) 2002-03-13
KR20010085938A (ko) 2001-09-07
IL142397A0 (en) 2002-03-10
CN100422319C (zh) 2008-10-01
CN1331743A (zh) 2002-01-16
EP1123386A1 (de) 2001-08-16
CA2347521C (en) 2010-02-23
NO327857B1 (no) 2009-10-05
IL142397A (en) 2008-03-20
DE59914102D1 (de) 2007-02-08
PT1123386E (pt) 2007-03-30
US6869783B1 (en) 2005-03-22
AU765480B2 (en) 2003-09-18
CA2347521A1 (en) 2000-04-27
ES2280125T3 (es) 2007-09-01
DE19848129A1 (de) 2000-04-20
JP2002527106A (ja) 2002-08-27
ZA200104066B (en) 2002-07-01
DK1123386T3 (da) 2007-05-07
WO2000023577A1 (de) 2000-04-27
HU228092B1 (en) 2012-10-29
NO20011912L (no) 2001-04-18
NO20011912D0 (no) 2001-04-18
AU6470899A (en) 2000-05-08
JP4489298B2 (ja) 2010-06-23
HUP0104802A2 (hu) 2002-04-29
EP1123386B1 (de) 2006-12-27
KR100715744B1 (ko) 2007-05-08
BR9914629A (pt) 2001-06-26
HUP0104802A3 (en) 2005-10-28
CZ302494B6 (cs) 2011-06-15
ID29136A (id) 2001-08-02
EE05008B1 (et) 2008-04-15

Similar Documents

Publication Publication Date Title
EE200100232A (et) Meetod kiraalsete karboksüülhapete saamiseks nitriilidest nitrilaasi või mikroorganismide abil, missisaldavad ühte geeni nitrilaasi jaoks
HUP0203704A2 (hu) L-Pankolakton hidroláz és eljárás D-pantolakton előállítására
EP1622921A4 (en) BETA-GLUCOSIDASE VARIANTS
EA200100718A1 (ru) Новая бактерия rhodococcus, ген нитрилазы, ген нитрилгидратазы и ген амидазы бактерии rhodococcus и способ получения карбоновых кислот с их использованием
WO2003006644A3 (de) Lipase/acyltransferase
BR0108883A (pt) Sequência de ácido nucleico isolado, construção de ácido nucleico, vetor, microorganismo recombinante, e, processo para a preparação de ácidos carboxìlicos quirais ou aquirais
DE602004021778D1 (de) Modifizierte nitrilasen und deren verwendung in verfahren zur herstellung von carbonsäuren
DK1136559T3 (da) Nukleotidsekvenser, der koder for dapC-genet, og fremgangsmåde til fremstilling af L-lysin
ATE360698T1 (de) Protein das an einer aktivierung von nitril hydratase teilnimmt,gen,plasmid und verfahren zur herstellung eines amid
EP1788075A4 (en) INDUSTRIAL UTILITY MICROORGANISM
ATE357524T1 (de) Citb gen aus corynebakterien und seine verwendung zur herstellung von l-aminosäuren
AU2001273977A1 (en) Novel nucleotide sequences coding for the glbo gene
DE60124921D1 (de) GENE, WELCHE FüR LUZIFERIN REGENERIERENDE PROTEINE KODIEREN, REKOMBINANTE DNA UND VERFAHREN ZUR HERSTELLUNG EINES LUZIFERIN REGENERIERENDEN PROTEINS
DK1409688T3 (da) Nukleinsyresekvenser der koder for enantioselektive amidaser
ATE325197T1 (de) D-carbamoylase aus arthrobacter crystallopoietes dsm 20117
WO2002012291A3 (en) Novel nucleotide sequences coding for the luxr gene and a process for the production of l-amino acids
WO2002002775A3 (de) Calpain-protease 12
AU2001276385A1 (en) Nucleotide sequences which code for the lysr3 gene
ATE339499T1 (de) Gene welche für proteine, die befähigt sind luziferin zu regenerieren, kodieren, rekombinante dna und verfahren zur herstellung von proteinen, die befähigt sind luziferin zu regenerieren
EP1408107A3 (en) Chlorohydrin and hydroxycarboxylic ester asymmetric hydrolase gene
EP1568775A4 (en) CANCER ASSOCIATED GEN
EP1371725A4 (en) NEW AMINOPEPTIDASE AND ITS GENE
WO2004090124A3 (en) Sequences encoding s-hydroxynitril lyases and their use in methods for the production of cyanohydrins

Legal Events

Date Code Title Description
KB4A Valid patent at the end of a year

Effective date: 20081231

KB4A Valid patent at the end of a year

Effective date: 20101231