BR9914629A - Sequência isolada de ácido nucleico, sequência de aminoácidos, construção de ácido nucleico, vetor, microorganismo, e, processo para preparar ácidos carboxìlicos quirais - Google Patents

Sequência isolada de ácido nucleico, sequência de aminoácidos, construção de ácido nucleico, vetor, microorganismo, e, processo para preparar ácidos carboxìlicos quirais

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Publication number
BR9914629A
BR9914629A BR9914629-0A BR9914629A BR9914629A BR 9914629 A BR9914629 A BR 9914629A BR 9914629 A BR9914629 A BR 9914629A BR 9914629 A BR9914629 A BR 9914629A
Authority
BR
Brazil
Prior art keywords
nucleic acid
acid sequence
carboxylic acids
acid sequences
microorganism
Prior art date
Application number
BR9914629-0A
Other languages
English (en)
Inventor
Loschke Marion Ress
Thomas Friedrich
Bernhard Hauer
Ralf Mattes
Dirk Engels
Original Assignee
Basf Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Basf Ag filed Critical Basf Ag
Publication of BR9914629A publication Critical patent/BR9914629A/pt

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/52—Genes encoding for enzymes or proenzymes
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H21/00—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/78—Hydrolases (3) acting on carbon to nitrogen bonds other than peptide bonds (3.5)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P41/00—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture
    • C12P41/006—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture by reactions involving C-N bonds, e.g. nitriles, amides, hydantoins, carbamates, lactames, transamination reactions, or keto group formation from racemic mixtures
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/40—Preparation of oxygen-containing organic compounds containing a carboxyl group including Peroxycarboxylic acids
    • C12P7/42—Hydroxy-carboxylic acids

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Biomedical Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Plant Pathology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Enzymes And Modification Thereof (AREA)

Abstract

"SEQuêNCIA ISOLADA DE áCIDO NUCLEICO, SEQuêNCIA DE AMINOáCIDOS, CONSTRUçãO DE áCIDO NUCLEICO, VETOR, MICROORGANISMO, E, PROCESSO PARA PREPARAR áCIDOS CARBOXìLICOS QUIRAIS". A invenção refere-se a seq³ências de ácido nucleico que codificam para um polipeptídeo apresentando atividade de nitrilase, a construções de ácido nucleico compreendendo as seq³ências de ácido nucleico, e a vetores compreendendo as seq³ências de ácido nucleico ou as construções de ácido nucleico. A invenção refere-se também a seq³ências de aminoácidos que são codificadas pelas seq³ências de ácido nucleico, e a microorganismos compreendendo as seq³ências de ácido nucleico, as construções de ácido nucleico ou vetores compreendendo as seq³ências de ácido nucleico ou as construções de ácido nucleico. A invenção refere-se adicionalmente a um processo para preparar ácidos carboxílicos quirais a partir dos nitrilos racêmicos.
BR9914629-0A 1998-10-19 1999-10-13 Sequência isolada de ácido nucleico, sequência de aminoácidos, construção de ácido nucleico, vetor, microorganismo, e, processo para preparar ácidos carboxìlicos quirais BR9914629A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19848129A DE19848129A1 (de) 1998-10-19 1998-10-19 Verfahren zur Herstellung chiraler Carbonsäuren aus Nitrilen mit Hilfe einer Nitrilase oder Mikroorganismen, die ein Gen für die Nitrilase enthalten
PCT/EP1999/007679 WO2000023577A1 (de) 1998-10-19 1999-10-13 Verfahren zur herstellung chiraler carbonsäuren aus nitrilen mit hilfe einer nitrilase oder mikroorganismen, die ein gen für die nitrilase enthalten

Publications (1)

Publication Number Publication Date
BR9914629A true BR9914629A (pt) 2001-06-26

Family

ID=7884933

Family Applications (1)

Application Number Title Priority Date Filing Date
BR9914629-0A BR9914629A (pt) 1998-10-19 1999-10-13 Sequência isolada de ácido nucleico, sequência de aminoácidos, construção de ácido nucleico, vetor, microorganismo, e, processo para preparar ácidos carboxìlicos quirais

Country Status (21)

Country Link
US (1) US6869783B1 (pt)
EP (1) EP1123386B1 (pt)
JP (1) JP4489298B2 (pt)
KR (1) KR100715744B1 (pt)
CN (1) CN100422319C (pt)
AT (1) ATE349517T1 (pt)
AU (1) AU765480B2 (pt)
BR (1) BR9914629A (pt)
CA (1) CA2347521C (pt)
CZ (1) CZ302494B6 (pt)
DE (2) DE19848129A1 (pt)
DK (1) DK1123386T3 (pt)
EE (1) EE05008B1 (pt)
ES (1) ES2280125T3 (pt)
HU (1) HU228092B1 (pt)
ID (1) ID29136A (pt)
IL (2) IL142397A0 (pt)
NO (1) NO327857B1 (pt)
PT (1) PT1123386E (pt)
WO (1) WO2000023577A1 (pt)
ZA (1) ZA200104066B (pt)

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DE19848129A1 (de) * 1998-10-19 2000-04-20 Basf Ag Verfahren zur Herstellung chiraler Carbonsäuren aus Nitrilen mit Hilfe einer Nitrilase oder Mikroorganismen, die ein Gen für die Nitrilase enthalten
US20040002147A1 (en) * 1999-12-29 2004-01-01 Desantis Grace Nitrilases
DE10010149A1 (de) * 2000-03-03 2001-09-06 Basf Ag Nitrilase aus Rhodococcus rhodochrous NCIMB 11216
US6455730B1 (en) 2000-08-04 2002-09-24 E. I. Du Pont De Nemours & Company Preparation of dicarboxylic acid monoesters from cyanocarboxylic acid esters
US6562603B2 (en) * 2000-08-04 2003-05-13 E. I. Du Pont De Nemours And Company 3-hydroxycarboxylic acid production and use in branched polymers
AU2001296653A1 (en) * 2000-10-04 2002-04-15 Maxygen, Inc. Enantioselective production of amino carboxylic acids
FR2822460B1 (fr) * 2001-03-26 2005-04-29 Rhodia Chimie Sa Procede de preparation enantioselectif d'acides carboxyliques optiquement actifs par hydrolyse enzymatique de nitriles
EP1578910A4 (en) 2001-06-21 2008-06-04 Verenium Corp NITRILASES
ITMI20011826A1 (it) * 2001-08-30 2003-03-02 Istituto Biochimico Italiano Microorganismo dotato di attivita' nitrile-idratasica/amidasica enantioselettiva e regioselettiva
DK1570060T3 (da) 2002-12-02 2007-11-05 Basf Ag L-rhamnoseinducerbare ekspressionssystemer
AU2003296731B2 (en) * 2003-01-08 2009-07-09 Basf Aktiengesellschaft Methods for preserving and/or storing cells having a nitrilase or nitrile hydratase activity
AT412092B (de) * 2003-02-27 2004-09-27 Dsm Fine Chem Austria Gmbh Verfahren zur herstellung chiraler alpha-hydroxycarbonsäuren durch enzymatische hydrolyse von chiralen cyanhydrinen
CN100445375C (zh) * 2003-02-27 2008-12-24 巴斯福股份公司 经修饰的腈水解酶及它们在产生羧酸的方法中的用途
CN102796770B (zh) * 2004-12-22 2014-06-04 纳幕尔杜邦公司 乙醇酸的酶促生产
US20100267100A1 (en) * 2007-03-21 2010-10-21 Ling Hua Enzymatic synthesis of optically pure beta-hydroxy carboxylic acids and their derivatives
US20090004720A1 (en) * 2007-06-26 2009-01-01 Ling Hua Smart Biocatalysts For Organic Synthesis
EP2338987A1 (en) 2009-11-16 2011-06-29 ZYRUS Beteiligungsgesellschaft mbH & Co. Patente I KG Whole cell biocatalyst
JP2013162746A (ja) * 2010-05-24 2013-08-22 Mitsui Chemicals Inc アミド化合物の製造方法
EP2643467A1 (de) 2010-11-24 2013-10-02 Basf Se Verfahren zur herstellung n-heterozyklischer optisch aktiver alkohole
KR101223664B1 (ko) * 2011-01-26 2013-01-17 재단법인 경북해양바이오산업연구원 나이트릴레이즈 ｒｍｎ１을 이용한 카르복실산의 제조방법
KR101223663B1 (ko) * 2011-01-26 2013-01-21 재단법인 경북해양바이오산업연구원 나이트릴레이즈 ｖｍｎ１을 이용한 카르복실산의 제조방법
KR101223666B1 (ko) * 2011-01-26 2013-01-17 재단법인 경북해양바이오산업연구원 나이트릴레이즈 ｏｒｎ을 이용한 카르복실산의 제조방법
KR101223665B1 (ko) * 2011-01-26 2013-01-17 재단법인 경북해양바이오산업연구원 나이트릴레이즈 ｒｍｎ２을 이용한 카르복실산의 제조방법
AU2021272383A1 (en) 2020-05-15 2022-12-08 Basf Se Improved method for the production of isoprenoids
WO2023105080A1 (en) 2021-12-10 2023-06-15 Basf Se Synthesis of glufosinate using a hydantoinase-based process
WO2023105079A1 (en) 2021-12-10 2023-06-15 Basf Se Enzymatic decarbamoylation of glufosinate derivatives
AR127936A1 (es) 2021-12-10 2024-03-13 Basf Se Actividad herbicida de alquilfosfinatos

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Also Published As

Publication number Publication date
ATE349517T1 (de) 2007-01-15
CZ20011382A3 (cs) 2002-03-13
KR20010085938A (ko) 2001-09-07
IL142397A0 (en) 2002-03-10
CN100422319C (zh) 2008-10-01
CN1331743A (zh) 2002-01-16
EP1123386A1 (de) 2001-08-16
CA2347521C (en) 2010-02-23
NO327857B1 (no) 2009-10-05
IL142397A (en) 2008-03-20
DE59914102D1 (de) 2007-02-08
PT1123386E (pt) 2007-03-30
US6869783B1 (en) 2005-03-22
AU765480B2 (en) 2003-09-18
CA2347521A1 (en) 2000-04-27
ES2280125T3 (es) 2007-09-01
DE19848129A1 (de) 2000-04-20
JP2002527106A (ja) 2002-08-27
ZA200104066B (en) 2002-07-01
DK1123386T3 (da) 2007-05-07
WO2000023577A1 (de) 2000-04-27
HU228092B1 (en) 2012-10-29
NO20011912L (no) 2001-04-18
EE200100232A (et) 2002-08-15
NO20011912D0 (no) 2001-04-18
AU6470899A (en) 2000-05-08
JP4489298B2 (ja) 2010-06-23
HUP0104802A2 (hu) 2002-04-29
EP1123386B1 (de) 2006-12-27
KR100715744B1 (ko) 2007-05-08
HUP0104802A3 (en) 2005-10-28
CZ302494B6 (cs) 2011-06-15
ID29136A (id) 2001-08-02
EE05008B1 (et) 2008-04-15

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