ATE450607T1 - Rhodococcus-stamm, nitrilase-gen aus rhodococcus, nitrilhydratas-gen und amidase-gen und verfahren zur herstellung carboxylsäuren unter deren verwendung - Google Patents

Rhodococcus-stamm, nitrilase-gen aus rhodococcus, nitrilhydratas-gen und amidase-gen und verfahren zur herstellung carboxylsäuren unter deren verwendung

Info

Publication number
ATE450607T1
ATE450607T1 AT00970065T AT00970065T ATE450607T1 AT E450607 T1 ATE450607 T1 AT E450607T1 AT 00970065 T AT00970065 T AT 00970065T AT 00970065 T AT00970065 T AT 00970065T AT E450607 T1 ATE450607 T1 AT E450607T1
Authority
AT
Austria
Prior art keywords
gene
carboxylic acids
rhodococcus
amidase
transformant
Prior art date
Application number
AT00970065T
Other languages
English (en)
Inventor
Hirobumi Aoki
Harumi Kamachi
Original Assignee
Showa Denko Kk
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from JP30321299A external-priority patent/JP2001120290A/ja
Priority claimed from JP2000021797A external-priority patent/JP2001136977A/ja
Priority claimed from JP2000107855A external-priority patent/JP2001292772A/ja
Application filed by Showa Denko Kk filed Critical Showa Denko Kk
Application granted granted Critical
Publication of ATE450607T1 publication Critical patent/ATE450607T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20—Bacteria; Culture media therefor
    • C12N1/205—Bacterial isolates
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/40—Preparation of oxygen-containing organic compounds containing a carboxyl group including Peroxycarboxylic acids
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/78—Hydrolases (3) acting on carbon to nitrogen bonds other than peptide bonds (3.5)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00—Microorganisms ; Processes using microorganisms
    • C12R2001/01—Bacteria or Actinomycetales ; using bacteria or Actinomycetales

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Biomedical Technology (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Virology (AREA)
  • Molecular Biology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Enzymes And Modification Thereof (AREA)
AT00970065T 1999-10-26 2000-10-25 Rhodococcus-stamm, nitrilase-gen aus rhodococcus, nitrilhydratas-gen und amidase-gen und verfahren zur herstellung carboxylsäuren unter deren verwendung ATE450607T1 (de)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
JP30321299A JP2001120290A (ja) 1999-10-26 1999-10-26 微生物によるカルボン酸類の製法
JP2000021797A JP2001136977A (ja) 1999-09-02 2000-01-26 ロドコッカス属細菌由来のニトリラーゼ遺伝子
JP2000107855A JP2001292772A (ja) 2000-04-10 2000-04-10 ロドコッカス属細菌由来のニトリルヒドラターゼ遺伝子およびアミダーゼ遺伝子
PCT/JP2000/007464 WO2001030994A1 (fr) 1999-10-26 2000-10-25 Nouveau rhodocoque, gene de la nitrilase, de la nitrilehydratase et de l'amidase, provenant du rhodocoque, et procede de production d'acides carboxyliques a l'aide de ceux-ci

Publications (1)

Publication Number Publication Date
ATE450607T1 true ATE450607T1 (de) 2009-12-15

Family

ID=27338591

Family Applications (1)

Application Number Title Priority Date Filing Date
AT00970065T ATE450607T1 (de) 1999-10-26 2000-10-25 Rhodococcus-stamm, nitrilase-gen aus rhodococcus, nitrilhydratas-gen und amidase-gen und verfahren zur herstellung carboxylsäuren unter deren verwendung

Country Status (11)

Country Link
US (1) US7118898B1 (de)
EP (1) EP1142997B1 (de)
KR (1) KR100540991B1 (de)
CN (1) CN1340101A (de)
AT (1) ATE450607T1 (de)
AU (1) AU7957100A (de)
CA (1) CA2356741C (de)
DE (1) DE60043424D1 (de)
EA (1) EA200100718A1 (de)
NO (1) NO328690B1 (de)
WO (1) WO2001030994A1 (de)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2004076655A1 (en) 2003-02-27 2004-09-10 Basf Aktiengesellschaft Modified nitrilases and their use in methods for the production of carboxylic acids
DE10315376B4 (de) * 2003-04-03 2005-07-14 Stockhausen Gmbh Verfahren zur Kultivierung des Nitrilhydratase-produzierenden Stammes RHODOCOCCUS RHODOCHROUS M33
EP1688491B1 (de) * 2003-10-31 2010-09-15 Daiichi Fine Chemical Co., Ltd. Neue plasmide und deren nutzung
EP1767624B1 (de) * 2004-05-26 2013-11-06 Mitsubishi Rayon Co., Ltd. Verbesserte nitrilhydratase
US7148051B2 (en) * 2004-08-16 2006-12-12 E. I. Du Pont De Nemours And Company Production of 3-hydroxycarboxylic acid using nitrilase
CN101268197A (zh) * 2005-09-22 2008-09-17 阿斯利康(瑞典)有限公司 用于将芳香卤代二腈转化为卤代氰基羧酸的新方法
US20100267100A1 (en) * 2007-03-21 2010-10-21 Ling Hua Enzymatic synthesis of optically pure beta-hydroxy carboxylic acids and their derivatives
US20090004720A1 (en) * 2007-06-26 2009-01-01 Ling Hua Smart Biocatalysts For Organic Synthesis
CN101663389B (zh) * 2008-03-24 2011-12-28 清华大学 敲除酰胺酶基因的产腈水合酶工程菌及其构建方法和应用
CN101434926B (zh) * 2008-10-31 2010-08-11 云南大学 一株可代谢尼古丁的红球菌及其应用
CN101875907B (zh) * 2009-04-28 2013-07-10 上海市农药研究所 一种可水解3-羟基丁腈的微生物菌株
KR101223663B1 (ko) 2011-01-26 2013-01-21 재단법인 경북해양바이오산업연구원 나이트릴레이즈 ｖｍｎ１을 이용한 카르복실산의 제조방법
CN103757068B (zh) * 2014-01-10 2016-06-29 江苏清泉化学股份有限公司 一种苯甲酸衍生物的制备方法
CN105420154B (zh) * 2015-12-16 2020-03-17 清华大学 双基因敲除重组红球菌、构建方法及其应用
AU2017388945B2 (en) * 2016-12-28 2021-06-03 Mitsui Chemicals, Inc. Mutant nitrile hydratase, nucleic acid coding said mutant nitrile hydratase, expression vector and transformant including said nucleic acid, production method for said mutant nitrile hydratase, and production method for amide compound
CN109136301A (zh) * 2018-09-19 2019-01-04 安徽瑞邦生物科技有限公司 一种水解制备烟酸的方法
CN109295124A (zh) * 2018-10-24 2019-02-01 张刘兵 一种水解制备烟酸的方法
CN110205315B (zh) * 2019-05-30 2021-01-01 中国石油大学(华东) 腈水解酶XiNit2及其编码基因和应用
CN110499274B (zh) * 2019-09-18 2021-11-23 清华大学 一种基因工程红球菌及其构建方法与应用
CN111378640A (zh) * 2020-03-12 2020-07-07 东莞市东阳光生物合成药有限公司 制备右旋酰胺酮洛芬的方法

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4629700A (en) * 1983-11-30 1986-12-16 Standard Oil Company (Indiana) Selective conversion of cyano compounds to amides and carboxylic acids
CN85107055A (zh) 1984-10-01 1986-06-10 诺沃工业联合股票公司 酶促工艺方法
AU627648B2 (en) * 1990-02-28 1992-08-27 Teruhiko Beppu Dna fragment encoding a polypeptide having nitrile hydratase activity, a transformant containing the gene and a process for the production of amides using the transformant
DE69231939T2 (de) 1991-03-04 2002-04-04 Mitsubishi Rayon Co Hybrid-Plasmid-Vektoren, die für Nitril-abbauende Enzyme kodierende Gene enthalten und Verfahren zur Herstellung von Amiden und Säuren
JPH0799980A (ja) * 1993-10-05 1995-04-18 Japan Energy Corp ニトリラーゼ活性を有するポリペプチドをコードする遺伝子ｄｎａ、およびこれを含有する形質転換体によるニトリル類からカルボン酸の製造法
RU2053300C1 (ru) 1993-12-17 1996-01-27 Государственный научно-исследовательский институт генетики и селекции промышленных микроорганизмов Штамм бактерий rhodococcus rhodochrous - продуцент нитрилгидратазы
WO1997006248A1 (en) * 1995-08-09 1997-02-20 Allied Colloids Limited Processes for the production of amidase
WO1997012964A2 (en) 1995-10-06 1997-04-10 E.I. Du Pont De Nemours And Company Nucleic acid fragments encoding stereospecific nitrile hydratase and amidase enzymes and recombinant microorganisms expressing those enzymes useful for the production of chiral amides and acides
DE19743683A1 (de) * 1997-10-02 1999-04-08 Basf Ag Verfahren zur Änderung der Substratspezifität von Enzymen
JP2001069978A (ja) * 1999-09-02 2001-03-21 Showa Denko Kk ロドコッカス属細菌由来のニトリルヒドラターゼ遺伝子およびアミダーゼ遺伝子
JP2001136977A (ja) 1999-09-02 2001-05-22 Showa Denko Kk ロドコッカス属細菌由来のニトリラーゼ遺伝子
JP2001292772A (ja) 2000-04-10 2001-10-23 Showa Denko Kk ロドコッカス属細菌由来のニトリルヒドラターゼ遺伝子およびアミダーゼ遺伝子
DE10010149A1 (de) 2000-03-03 2001-09-06 Basf Ag Nitrilase aus Rhodococcus rhodochrous NCIMB 11216

Also Published As

Publication number Publication date
CN1340101A (zh) 2002-03-13
NO328690B1 (no) 2010-04-26
NO20013209L (no) 2001-07-03
KR20010084883A (ko) 2001-09-06
KR100540991B1 (ko) 2006-01-10
NO20013209D0 (no) 2001-06-26
EP1142997A1 (de) 2001-10-10
WO2001030994A1 (fr) 2001-05-03
EA200100718A1 (ru) 2001-12-24
CA2356741C (en) 2011-01-25
DE60043424D1 (de) 2010-01-14
AU7957100A (en) 2001-05-08
CA2356741A1 (en) 2001-05-03
EP1142997A4 (de) 2004-03-24
US7118898B1 (en) 2006-10-10
EP1142997B1 (de) 2009-12-02

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