ATE360698T1 - Protein das an einer aktivierung von nitril hydratase teilnimmt,gen,plasmid und verfahren zur herstellung eines amid - Google Patents

Protein das an einer aktivierung von nitril hydratase teilnimmt,gen,plasmid und verfahren zur herstellung eines amid

Info

Publication number
ATE360698T1
ATE360698T1 AT99301990T AT99301990T ATE360698T1 AT E360698 T1 ATE360698 T1 AT E360698T1 AT 99301990 T AT99301990 T AT 99301990T AT 99301990 T AT99301990 T AT 99301990T AT E360698 T1 ATE360698 T1 AT E360698T1
Authority
AT
Austria
Prior art keywords
gene
nitrile hydratase
activation
producing
nitrile
Prior art date
Application number
AT99301990T
Other languages
English (en)
Inventor
Kiyoshi Ito
Miyuki Tsuruoka
Tadashi Suzuki
Seiya Nikumaru
Takeshi Nakamura
Original Assignee
Mitsui Chemicals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Mitsui Chemicals Inc filed Critical Mitsui Chemicals Inc
Application granted granted Critical
Publication of ATE360698T1 publication Critical patent/ATE360698T1/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/88Lyases (4.)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00Preparation of nitrogen-containing organic compounds
    • C12P13/02Amides, e.g. chloramphenicol or polyamides; Imides or polyimides; Urethanes, i.e. compounds comprising N-C=O structural element or polyurethanes
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02PCLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00Technologies relating to chemical industry
    • Y02P20/50Improvements relating to the production of bulk chemicals
    • Y02P20/52Improvements relating to the production of bulk chemicals using catalysts, e.g. selective catalysts

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biomedical Technology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
AT99301990T 1998-03-16 1999-03-16 Protein das an einer aktivierung von nitril hydratase teilnimmt,gen,plasmid und verfahren zur herstellung eines amid ATE360698T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP06552098A JP3408737B2 (ja) 1998-03-16 1998-03-16 ニトリルヒドラターゼの活性化に関与するタンパク質及びそれをコードする遺伝子

Publications (1)

Publication Number Publication Date
ATE360698T1 true ATE360698T1 (de) 2007-05-15

Family

ID=13289395

Family Applications (1)

Application Number Title Priority Date Filing Date
AT99301990T ATE360698T1 (de) 1998-03-16 1999-03-16 Protein das an einer aktivierung von nitril hydratase teilnimmt,gen,plasmid und verfahren zur herstellung eines amid

Country Status (9)

Country Link
US (1) US6730508B1 (de)
EP (1) EP0943686B1 (de)
JP (1) JP3408737B2 (de)
KR (1) KR100323899B1 (de)
CN (1) CN1250568C (de)
AT (1) ATE360698T1 (de)
AU (1) AU727092B2 (de)
DE (1) DE69935880T2 (de)
ID (1) ID22189A (de)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TWI296652B (en) 2000-03-29 2008-05-11 Mitsui Chemicals Inc Production process of amide compound
JP2004194588A (ja) 2002-12-19 2004-07-15 Mitsui Chemicals Inc 新規なニトリルヒドラターゼ
JP4813215B2 (ja) * 2005-03-08 2011-11-09 三星電子株式会社 プローブセットの設計方法、それにより設計されたプローブセット、前記プローブセットを備えるマイクロアレイ、前記方法をコンピュータが実行可能にするプログラムを記録したコンピュータ読み取り可能な記録媒体、および前記プローブセットを利用した標的配列の同定方法
US7531343B2 (en) 2006-01-30 2009-05-12 Georgia State University Research Foundation, Inc. Induction and stabilization of enzymatic activity in microorganisms
EP1842907A1 (de) 2006-04-07 2007-10-10 B.R.A.I.N. Ag Eine Gruppe neuer enantioselectiver mikrobieller Nitrilhydratasen mit breiter Substratspezifität
JP5120852B2 (ja) * 2006-07-06 2013-01-16 国立大学法人 筑波大学 新規タンパク質複合体、該タンパク質複合体を用いたコバルト型低分子量ニトリルヒドラターゼ成熟化方法、成熟化コバルト型低分子量ニトリルヒドラターゼ、及び該ニトリルヒドラターゼを用いた方法
US7943549B2 (en) 2007-04-02 2011-05-17 Georgia State University Research Foundation, Inc. Biological-based catalyst to delay plant development processes
KR101532467B1 (ko) 2008-11-14 2015-07-06 미쓰이 가가쿠 가부시키가이샤 니트릴 히드라타아제 변이체
JP6454320B2 (ja) 2013-03-14 2019-01-16 ジョージア・ステイト・ユニバーシティ・リサーチ・ファウンデーション・インコーポレイテッドGeorgia State University Research Foundation, Inc. 植物における低温障害反応の防止または遅延
CA2903704A1 (en) 2013-03-14 2014-10-02 Georgia State University Research Foundation, Inc. Inhibiting or reducing fungal growth
ES2784277T3 (es) * 2014-09-30 2020-09-23 Solenis Technologies Cayman Lp Método de cultivo de microorganismos que tienen actividad de nitrilo hidratasa
CN119343452A (zh) 2022-06-30 2025-01-21 三井化学株式会社 突变型腈水合酶、编码该突变型腈水合酶的核酸、含有该核酸的载体及转化体、该突变型腈水合酶的制造方法、及酰胺化合物的制造方法
CN116574750B (zh) * 2023-04-21 2023-12-05 大连理工大学 一种提高腈类化合物生物转化效率的腈水合酶重组质粒及其构建方法与应用

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0856684A (ja) 1994-08-16 1996-03-05 Mitsui Toatsu Chem Inc 微生物によるアミド化合物の製造法
WO1997012964A2 (en) 1995-10-06 1997-04-10 E.I. Du Pont De Nemours And Company Nucleic acid fragments encoding stereospecific nitrile hydratase and amidase enzymes and recombinant microorganisms expressing those enzymes useful for the production of chiral amides and acides
EP0790310B1 (de) 1996-02-14 2008-10-08 Mitsui Chemicals, Inc. Nitril-Hydratase, ihre Derivate und Verfahren zur Herstellung von Verbindungen

Also Published As

Publication number Publication date
HK1021983A1 (en) 2000-07-21
US6730508B1 (en) 2004-05-04
DE69935880T2 (de) 2008-01-10
EP0943686A3 (de) 2000-09-06
CN1250568C (zh) 2006-04-12
AU2039799A (en) 1999-11-04
JPH11253168A (ja) 1999-09-21
KR100323899B1 (ko) 2002-02-09
AU727092B2 (en) 2000-11-30
EP0943686A2 (de) 1999-09-22
DE69935880D1 (de) 2007-06-06
ID22189A (id) 1999-09-16
JP3408737B2 (ja) 2003-05-19
CN1235978A (zh) 1999-11-24
KR19990077942A (ko) 1999-10-25
EP0943686B1 (de) 2007-04-25

Similar Documents

Publication Publication Date Title
ATE360698T1 (de) Protein das an einer aktivierung von nitril hydratase teilnimmt,gen,plasmid und verfahren zur herstellung eines amid
EE05008B1 (et) Meetod kiraalsete karboksüülhapete saamiseks nitriilidest nitrilaasi v?i mikroorganismide abil, missisaldavad ühte geeni nitrilaasi jaoks
DE3877869D1 (de) Verfahren zur biologischen herstellung von amiden.
DE60137847D1 (de) Eg-vegf nukleinsäuren und polypeptide und verfahren zur deren verwendung
KR910021473A (ko) 니트릴히드라타제 활성을 갖는 폴리헵티드를 코팅하는 dna단편, 이것을 함유하는 형질 전환체 및 이 전환체를 사용하여 아미드류를 제조하는 방법
BR0015114A (pt) Sequências de ácido nucléico e de aminoácido, construção de ácido nucleico, vetor, microorganismo, l-pantolactona hidrolase, e, processo para preparar d-pantolactona
ATE245700T1 (de) Für das thre-gen kodierende nukleotidsequenzen und verfahren zur fermentativen herstellung von l-threonin mit coryneformen bakterien
ATE90944T1 (de) Fuer ein hirudinaehnliches protein kodierende dns- sequenz und verfahren zur herstellung eines solchen proteins.
EP1365025A4 (de) Agarase und gen dafür
DE69434292D1 (de) Für adseverin kodierendes gen
DE60110893D1 (de) Kabeljau-spezifische urazil-dna glykosilase, dafür kodierendes gen, selbiges gen beinhaltende, rekombinante dna oder operative teile davon, ein verfahren zur herstellung des proteins und die anwendung des protein oder der operativen teile zur überwachung und kontrolle der pcr
DE602004021778D1 (de) Modifizierte nitrilasen und deren verwendung in verfahren zur herstellung von carbonsäuren
ATE362544T1 (de) Polypeptide mit alpha-h alpha amino acid amide racemase aktivitität und nukleinsäuren kodierend dafür
BR0108883A (pt) Sequência de ácido nucleico isolado, construção de ácido nucleico, vetor, microorganismo recombinante, e, processo para a preparação de ácidos carboxìlicos quirais ou aquirais
DE69934017D1 (de) 2,6-beta-d-fruktanhydrolase enzym und verfahren zu dessen verwendung
ATE439430T1 (de) Mutanten für die herstellung von d-aminosäuren
DE3888386D1 (de) Verfahren zur Herstellung von Proteinen.
DE50014875D1 (de) Verfahren zum herstellen eines rekombinanten proteins
ATE252635T1 (de) Verfahren zur fermentativen herstellung von l- aminosäuren und für das accda gen codierende nukleotidsequenzen
AU2002346803A1 (en) Genes encoding for carbon metabolism and energy-producing proteins
ATE465268T1 (de) Verfahren zur mikrobiologischen isomerisierung von alpha-hydroxycarbonsäuren
ATE451457T1 (de) Verfahren zur dipeptidherstellung
ATE458037T1 (de) Grosstechnisch geeigneter mikroorganismus
ATE423198T1 (de) Sphingolipid-ceramiddeacylase-gen
DE59510916D1 (de) Verbessertes, induktionsfreies Verfahren zur Gentechnischen Herstellung von Glutarylamidase

Legal Events

Date Code Title Description
RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties