DE60313866D1 - Polypeptide mit alpha-h alpha amino acid amide racemase aktivitität und nukleinsäuren kodierend dafür - Google Patents

Polypeptide mit alpha-h alpha amino acid amide racemase aktivitität und nukleinsäuren kodierend dafür

Info

Publication number
DE60313866D1
DE60313866D1 DE60313866T DE60313866T DE60313866D1 DE 60313866 D1 DE60313866 D1 DE 60313866D1 DE 60313866 T DE60313866 T DE 60313866T DE 60313866 T DE60313866 T DE 60313866T DE 60313866 D1 DE60313866 D1 DE 60313866D1
Authority
DE
Germany
Prior art keywords
alpha
amino acid
acid amide
nucleic acids
racemase activity
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60313866T
Other languages
English (en)
Other versions
DE60313866T2 (de
Inventor
Wilhelmus Hubertus Boesten
Petronella C Raemakers-Franken
Theodorus Sonke
Gerrit Jan Euverink
Pieter Grijpstra
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
DSM IP Assets BV
Original Assignee
DSM IP Assets BV
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by DSM IP Assets BV filed Critical DSM IP Assets BV
Application granted granted Critical
Publication of DE60313866D1 publication Critical patent/DE60313866D1/de
Publication of DE60313866T2 publication Critical patent/DE60313866T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P41/00—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture
    • C12P41/006—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture by reactions involving C-N bonds, e.g. nitriles, amides, hydantoins, carbamates, lactames, transamination reactions, or keto group formation from racemic mixtures
    • C12P41/007—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture by reactions involving C-N bonds, e.g. nitriles, amides, hydantoins, carbamates, lactames, transamination reactions, or keto group formation from racemic mixtures by reactions involving acyl derivatives of racemic amines
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/90—Isomerases (5.)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00—Preparation of nitrogen-containing organic compounds
    • C12P13/02—Amides, e.g. chloramphenicol or polyamides; Imides or polyimides; Urethanes, i.e. compounds comprising N-C=O structural element or polyurethanes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00—Preparation of nitrogen-containing organic compounds
    • C12P13/04—Alpha- or beta- amino acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Analytical Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
DE60313866T 2002-06-14 2003-06-13 Polypeptide mit alpha-h alpha amino acid amide racemase aktivitität und nukleinsäuren kodierend dafür Expired - Lifetime DE60313866T2 (de)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
EP02100711 2002-06-14
EP02100711 2002-06-14
EP02080631 2002-12-20
EP02080631 2002-12-20
PCT/NL2003/000423 WO2003106691A1 (en) 2002-06-14 2003-06-13 POLYPEPTIDES HAVING α- H-α-AMINO ACID AMIDE RACEMASE ACTIVITY AND NUCLEIC ACIDS ENCODING THE SAME

Publications (2)

Publication Number Publication Date
DE60313866D1 true DE60313866D1 (de) 2007-06-28
DE60313866T2 DE60313866T2 (de) 2008-04-17

Family

ID=29737945

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60313866T Expired - Lifetime DE60313866T2 (de) 2002-06-14 2003-06-13 Polypeptide mit alpha-h alpha amino acid amide racemase aktivitität und nukleinsäuren kodierend dafür

Country Status (9)

Country Link
US (1) US7371555B2 (de)
EP (1) EP1513946B1 (de)
JP (1) JP4402587B2 (de)
CN (1) CN100471950C (de)
AT (1) ATE362544T1 (de)
AU (1) AU2003238717A1 (de)
DE (1) DE60313866T2 (de)
ES (1) ES2285128T3 (de)
WO (1) WO2003106691A1 (de)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20050166498A1 (en) * 1999-12-17 2005-08-04 Oakey David D. Carpet tile with cutout section, method and apparatus for production and method of installation
WO2005068643A2 (en) * 2004-01-19 2005-07-28 Dsm Ip Assets B.V. Biochemical synthesis of 6-amino caproic acid
DE102004013842A1 (de) 2004-03-20 2005-10-13 Degussa Ag Nitrilhydratasen aus Metagenombibliotheken
EP2245137B1 (de) 2008-01-22 2017-08-16 Genomatica, Inc. Verfahren und organismen zur nutzung von synthesegas oder anderen gasförmigen kohlenstoffquellen und methanol
CA3081506A1 (en) 2008-03-05 2009-09-11 Genomatica, Inc. Long chain alcohol-producing organisms
EP2172545A1 (de) 2008-09-24 2010-04-07 DSM IP Assets B.V. Herstellung von gereinigter Peptid-Deformylase
CA2747241A1 (en) 2008-12-12 2010-06-17 Celexion, Llc Biological synthesis of difunctional alkanes from alpha ketoacids
US8404465B2 (en) 2009-03-11 2013-03-26 Celexion, Llc Biological synthesis of 6-aminocaproic acid from carbohydrate feedstocks
EP2424975B1 (de) 2009-04-30 2016-07-06 Genomatica, Inc. Organismen zur herstellung von 1,3-butandiol
AU2010242849A1 (en) 2009-04-30 2011-11-24 Genomatica, Inc. Organisms for the production of isopropanol, n-butanol, and isobutanol
EP3190174A1 (de) 2009-08-05 2017-07-12 Genomatica, Inc. Aus muconsäureproduzierenden mikroorganismen gewonnene halbsynthetische terephthalsäure
WO2011050326A1 (en) 2009-10-23 2011-04-28 Genomatica, Inc. Microorganisms for the production of aniline
WO2011094131A1 (en) 2010-01-29 2011-08-04 Genomatica, Inc. Microorganisms and methods for the biosynthesis of p-toluate and terephthalate
US9023636B2 (en) 2010-04-30 2015-05-05 Genomatica, Inc. Microorganisms and methods for the biosynthesis of propylene
EP2593556B1 (de) 2010-07-14 2017-08-30 DPx Holdings B.V. Enzymatisches verfahren zur (r)-selektive amination
CA2806230A1 (en) 2010-07-26 2012-02-09 Genomatica, Inc. Microorganisms and methods for the biosynthesis of aromatics, 2,4-pentadienoate and 1,3-butadiene
CN109337832B (zh) * 2018-03-14 2021-06-15 重庆理工大学 一种耐高氨氮异养硝化-好氧反硝化的苍白杆菌及其应用
CN110317742B (zh) * 2019-03-22 2021-01-01 厦门大学 一株耐铬的石油烃降解菌株Tph3-32及其应用

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK261685A (da) * 1985-06-11 1986-12-12 Novo Industri As Fremgangsmaade til fremstilling af optisk aktive, organiske forbindelser
JPS63129984A (ja) * 1986-11-21 1988-06-02 Toray Ind Inc α−アミノ−ε−カプロラクタム・ラセマ−ゼ
ES2051892T3 (es) * 1987-08-17 1994-07-01 Novo Industri As Procedimiento para preparar productos quimicos organicos.
DE3816063A1 (de) * 1988-05-06 1989-11-23 Schering Ag Verfahren zur herstellung von l-aminosaeuren und aminosaeure-amiden
EP0383403A1 (de) * 1989-02-16 1990-08-22 Stamicarbon B.V. Verfahren zur Herstellung von organischen chemischen Produkten
NL9100038A (nl) * 1991-01-11 1992-08-03 Stamicarbon Enzym-gekatalyseerde bereiding van optisch aktieve carbonzuren.
WO2000066751A1 (en) 1999-04-29 2000-11-09 Dsm N.V. Expression cassette for efficient production of a protein
JP4122416B2 (ja) 2004-02-24 2008-07-23 関西ティー・エル・オー株式会社 α−アミノ−ε−カプロラクタムラセマーゼを用いた、Ｄ及びＬ−アミノ酸アミドの混合物の製造方法、Ｄ又はＬ−アミノ酸の製造方法、Ｄ又はＬ−アミノ酸アミドの製造方法

Also Published As

Publication number Publication date
ES2285128T3 (es) 2007-11-16
EP1513946A1 (de) 2005-03-16
WO2003106691A1 (en) 2003-12-24
US20040248274A1 (en) 2004-12-09
CN1675371A (zh) 2005-09-28
EP1513946B1 (de) 2007-05-16
DE60313866T2 (de) 2008-04-17
ATE362544T1 (de) 2007-06-15
US7371555B2 (en) 2008-05-13
JP4402587B2 (ja) 2010-01-20
AU2003238717A1 (en) 2003-12-31
JP2005529611A (ja) 2005-10-06
CN100471950C (zh) 2009-03-25

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