IL128574A - Process for making intermediates for making fluorophenicol - Google Patents

Process for making intermediates for making fluorophenicol

Info

Publication number
IL128574A
IL128574A IL12857497A IL12857497A IL128574A IL 128574 A IL128574 A IL 128574A IL 12857497 A IL12857497 A IL 12857497A IL 12857497 A IL12857497 A IL 12857497A IL 128574 A IL128574 A IL 128574A
Authority
IL
Israel
Prior art keywords
formula
compound
alkyl
aryl
benzyl
Prior art date
Application number
IL12857497A
Other languages
English (en)
Hebrew (he)
Other versions
IL128574A0 (en
Original Assignee
Schering Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=24808601&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=IL128574(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Schering Corp filed Critical Schering Corp
Publication of IL128574A0 publication Critical patent/IL128574A0/xx
Publication of IL128574A publication Critical patent/IL128574A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
    • C07D263/02—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
    • C07D263/02—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
    • C07D263/08—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D263/16—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D263/28—Nitrogen atoms not forming part of a nitro radical

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
IL12857497A 1996-08-19 1997-08-18 Process for making intermediates for making fluorophenicol IL128574A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/699,271 US5663361A (en) 1996-08-19 1996-08-19 Process for preparing intermediates to florfenicol
PCT/US1997/014205 WO1998007709A1 (en) 1996-08-19 1997-08-18 Process for preparing intermediates to florfenicol

Publications (2)

Publication Number Publication Date
IL128574A0 IL128574A0 (en) 2000-01-31
IL128574A true IL128574A (en) 2002-04-21

Family

ID=24808601

Family Applications (1)

Application Number Title Priority Date Filing Date
IL12857497A IL128574A (en) 1996-08-19 1997-08-18 Process for making intermediates for making fluorophenicol

Country Status (31)

Country Link
US (1) US5663361A (pt)
EP (1) EP0922040B2 (pt)
JP (1) JP3274868B2 (pt)
KR (1) KR100286851B1 (pt)
CN (1) CN1097583C (pt)
AR (1) AR008298A1 (pt)
AT (1) ATE283847T1 (pt)
AU (1) AU714495B2 (pt)
BR (1) BR9711318B1 (pt)
CA (1) CA2264116C (pt)
CO (1) CO4560550A1 (pt)
CZ (1) CZ297915B6 (pt)
DE (1) DE69731835T3 (pt)
DK (1) DK0922040T3 (pt)
ES (1) ES2234026T5 (pt)
HK (1) HK1017890A1 (pt)
HU (1) HU229610B1 (pt)
ID (1) ID18047A (pt)
IL (1) IL128574A (pt)
MY (1) MY115679A (pt)
NO (1) NO312962B1 (pt)
NZ (1) NZ334111A (pt)
PE (1) PE99798A1 (pt)
PL (2) PL198553B1 (pt)
PT (1) PT922040E (pt)
SI (1) SI0922040T1 (pt)
SK (1) SK286124B6 (pt)
TR (2) TR199900354T2 (pt)
TW (1) TW381075B (pt)
WO (1) WO1998007709A1 (pt)
ZA (1) ZA977406B (pt)

Families Citing this family (40)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1173933C (zh) * 2001-06-01 2004-11-03 中国科学院上海有机化学研究所 一种从l型取代苯丝氨酸酯制备d－（－）－苏式1－r－取代苯基－2－二氯乙酰氨基－3－氟－1－丙醇的方法
WO2003077828A2 (en) * 2002-03-08 2003-09-25 Schering-Plough, Ltd. Novel florfenicol-type antibiotics
PE20050386A1 (es) * 2003-05-29 2005-06-23 Schering Plough Ltd Composiciones farmaceuticas de florfenicol
US7439268B2 (en) * 2003-07-18 2008-10-21 Idexx Laboratories Compositions containing prodrugs of florfenicol and methods of use
US20050049210A1 (en) * 2003-08-27 2005-03-03 Idexx Laboratories, Inc. Methods for the controlled delivery of pharmacologically active compounds
US7126005B2 (en) * 2003-10-06 2006-10-24 Aurobindo Pharma Limited Process for preparing florfenicol
CA2576589C (en) * 2004-08-13 2013-11-12 Schering-Plough Ltd. Pharmaceutical formulation comprising an antibiotic, a triazole and a corticosteroid
WO2006034333A2 (en) 2004-09-23 2006-03-30 Schering-Plough Ltd. Control of parasites in animals by the use of novel trifluoromethanesulfonanilide oxime ether derivatives
ATE446677T1 (de) * 2004-11-19 2009-11-15 Schering Plough Ltd Kontrolle von parasiten bei tieren mittels verwendung von parasitiziden 2-phenyl-3-(1h- pyrrol-2-yl) acrylonitril-derivaten
AU2005318187B2 (en) * 2004-12-21 2010-12-16 Intervet International B.V. Injectable veterinary composition
CA2609574A1 (en) * 2005-06-09 2006-12-21 Schering-Plough Ltd. Control of parasites in animals by n-[(phenyloxy)phenyl]-1,1,1-trifluoromethanesulfonamide and n-[(phenylsulfanyl)phenyl]-1,1,1-trifluoromethanesulfonamide derivatives
ES2459205T3 (es) * 2005-09-07 2014-05-08 Intervet International Bv Proceso para preparar compuestos de oxazolidina éster y su conversión en florfenicol
US8119667B2 (en) * 2005-12-29 2012-02-21 Schering-Plough Animal Health Corporation Carbonates of fenicol antibiotics
US7518017B2 (en) 2006-02-17 2009-04-14 Idexx Laboratories Fenicol compounds and methods synthesizing 2-trifluoroacetamido-3-substituted propiophenone compounds
US20070238700A1 (en) * 2006-04-10 2007-10-11 Winzenberg Kevin N N-phenyl-1,1,1-trifluoromethanesulfonamide hydrazone derivative compounds and their usage in controlling parasites
CA2672586A1 (en) * 2006-12-13 2008-06-26 Schering-Plough Ltd. Water-soluble prodrugs of florfenicol and its analogs
WO2008076256A1 (en) * 2006-12-13 2008-06-26 Schering-Plough Ltd. Water-soluble prodrugs of chloramphenicol, thiamphenicol, and analogs thereof
JP2010525059A (ja) * 2007-04-27 2010-07-22 シェーリング−プラウ・リミテッド シクロデキストリンを用いてフロルフェニコールおよび構造的に関連する抗生物質の溶解度を高めるための化合物および方法
US20080319200A1 (en) * 2007-05-30 2008-12-25 Schering-Plough Animal Health Corp. Process for preparing oxazoline-protected aminodiol compounds useful as intermediates to florfenicol
TWI430995B (zh) 2007-06-26 2014-03-21 Du Pont 萘異唑啉無脊椎有害動物控制劑
PT2957284T (pt) 2007-06-27 2018-04-23 Du Pont Método de controlo de pragas em animais
WO2009015111A2 (en) * 2007-07-25 2009-01-29 Intervet Intermatonal B.V. Process for preparing oxazolidine-and oxazolidinone-aminodiols and related intermediates
US7550625B2 (en) * 2007-10-19 2009-06-23 Idexx Laboratories Esters of florfenicol
WO2009061780A1 (en) * 2007-11-09 2009-05-14 Schering-Plough Limited Fast release solid formulation, preparation and use thereof
TWI468407B (zh) 2008-02-06 2015-01-11 Du Pont 中離子農藥
CN102131772B (zh) * 2008-07-30 2015-03-11 英特威国际有限公司 用作氟苯尼考的中间体的*唑啉-保护的氨基二醇化合物的制备方法
UA110924C2 (uk) 2009-08-05 2016-03-10 Е. І. Дю Пон Де Немур Енд Компані Мезоіонні пестициди
UA107804C2 (en) 2009-08-05 2015-02-25 Du Pont Mixtures of pesticides mezoionnyh
MX2012001646A (es) 2009-08-05 2012-03-21 Du Pont Pesticidas mesoionicos.
AU2010279574A1 (en) 2009-08-05 2012-02-09 E. I. Du Pont De Nemours And Company Mesoionic pesticides
BRPI1002023A2 (pt) 2010-03-01 2011-10-25 Nanocore Biotecnologia S A forma farmacêutica sólida de dissolução rápida para tratamento de infecções bacterianas
DK2576523T3 (en) 2010-05-27 2016-04-18 Du Pont A crystalline form of 4- [5- [3-chloro-5- (trifluoromethyl) phenyl] -4,5-dihydro-5- (trifluoromethyl) -3-isoxazolyl] -N- [2-oxo-2 - [( 2,2,2-trifluoroethyl) amino] ethyl] - 1-naphthalenecarboxamide
WO2012087630A1 (en) 2010-12-20 2012-06-28 E.I. Du Pont De Nemours And Company Pyridine and pyrimidine compounds for controlling invertebrate
WO2013158422A1 (en) 2012-04-17 2013-10-24 E. I. Du Pont De Nemours And Company Heterocyclic compounds for controlling invertebrate pests
CN102911133B (zh) * 2012-10-31 2014-07-02 绍兴民生医药有限公司 (4r,5r)-2-二氯甲基-4,5-二氢-5-(4-甲砜基苯基)-4-恶唑甲醇的纯化方法
CN103254147B (zh) * 2013-04-19 2016-04-06 浙江科技学院 一种d-苏式-2-(二氯甲基)-4,5-二氢-5-[对-（甲砜基）苯基]-4-噁唑甲醇的制备方法
CN106278964B (zh) * 2016-07-31 2018-01-16 浙江润康药业有限公司 氟苯尼考的制备方法
CN106631872A (zh) * 2016-12-13 2017-05-10 浙江普洛家园药业有限公司 一种氟苯尼考类似物中间体的合成方法
CN110272856B (zh) * 2019-05-08 2022-05-03 江南大学 一种表达d-苏氨酸醛缩酶的重组菌及其构建方法与应用
CN117466787B (zh) * 2023-12-28 2024-03-22 山东国邦药业有限公司 一种氟苯尼考中间体的制备方法

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2759001A (en) * 1952-03-01 1956-08-14 Parke Davis & Co Process for the production of delta2-oxazolines
US4361557A (en) * 1980-01-28 1982-11-30 Schering Corporation 1-Aryl-2-acylamido-3-fluoro-1-propanol acylates, methods for their use as anti-bacterial agents and compositions useful therefor
ATE143953T1 (de) * 1983-06-02 1996-10-15 Zambon Spa Verfahren zur herstellung von 1-(phenyl)-1- hydroxy-2-amino-3-fluor-propan-derivaten
US4876352A (en) * 1988-09-14 1989-10-24 Schering Corporation Pressurized fluorination of hydroxy alkyl groups
KR920701469A (ko) † 1989-05-15 1992-08-11 스테이너 브이. 캔스태드 향균성 화합물 및 이의 중간물질의 제조방법
DK0555340T3 (da) * 1990-10-25 1995-03-06 Schering Corp Fremgangsmåde til fremstilling af florfenicol, analoger heraf og oxazolinmellemprodukter dertil

Also Published As

Publication number Publication date
BR9711318A (pt) 1999-08-17
DE69731835T3 (de) 2013-12-05
NZ334111A (en) 1999-10-28
DK0922040T3 (da) 2005-04-04
NO312962B1 (no) 2002-07-22
MY115679A (en) 2003-08-30
DE69731835T2 (de) 2005-07-21
SK286124B6 (sk) 2008-04-07
CN1233244A (zh) 1999-10-27
DE69731835D1 (de) 2005-01-05
KR100286851B1 (ko) 2001-04-16
NO990756L (no) 1999-02-18
KR20000068178A (ko) 2000-11-25
AU4063897A (en) 1998-03-06
ES2234026T3 (es) 2005-06-16
EP0922040B2 (en) 2013-07-17
ATE283847T1 (de) 2004-12-15
CA2264116C (en) 2002-07-02
CO4560550A1 (es) 1998-02-10
WO1998007709A1 (en) 1998-02-26
PL331644A1 (en) 1999-08-02
TR200800474T2 (tr) 2008-04-21
EP0922040A1 (en) 1999-06-16
SK19999A3 (en) 2000-02-14
JP3274868B2 (ja) 2002-04-15
AR008298A1 (es) 1999-12-29
TR199900354T2 (xx) 1999-05-21
ES2234026T5 (es) 2013-11-12
PL198553B1 (pl) 2008-06-30
TW381075B (en) 2000-02-01
HUP9904166A2 (hu) 2000-05-28
ID18047A (id) 1998-02-19
HUP9904166A3 (en) 2001-11-28
ZA977406B (en) 1998-02-18
IL128574A0 (en) 2000-01-31
JP2000501424A (ja) 2000-02-08
EP0922040B1 (en) 2004-12-01
BR9711318B1 (pt) 2009-01-13
CN1097583C (zh) 2003-01-01
CA2264116A1 (en) 1998-02-26
PE99798A1 (es) 1998-12-28
CZ297915B6 (cs) 2007-04-25
US5663361A (en) 1997-09-02
PT922040E (pt) 2005-02-28
HU229610B1 (en) 2014-03-28
PL196454B1 (pl) 2008-01-31
SI0922040T1 (en) 2005-02-28
HK1017890A1 (en) 1999-12-03
CZ54099A3 (cs) 1999-07-14
AU714495B2 (en) 2000-01-06
NO990756D0 (no) 1999-02-18

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