DK0555340T3 - Fremgangsmåde til fremstilling af florfenicol, analoger heraf og oxazolinmellemprodukter dertil - Google Patents

Fremgangsmåde til fremstilling af florfenicol, analoger heraf og oxazolinmellemprodukter dertil

Info

Publication number
DK0555340T3
DK0555340T3 DK91920162.4T DK91920162T DK0555340T3 DK 0555340 T3 DK0555340 T3 DK 0555340T3 DK 91920162 T DK91920162 T DK 91920162T DK 0555340 T3 DK0555340 T3 DK 0555340T3
Authority
DK
Denmark
Prior art keywords
formula
compound
oxazoline
oxazoline compound
pct
Prior art date
Application number
DK91920162.4T
Other languages
English (en)
Inventor
Jon E Clark
Doris P Schumacher
Guang-Zhong Wu
Original Assignee
Schering Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering Corp filed Critical Schering Corp
Application granted granted Critical
Publication of DK0555340T3 publication Critical patent/DK0555340T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
    • C07D263/02—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
    • C07D263/08—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D263/10—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C317/00—Sulfones; Sulfoxides
    • C07C317/26—Sulfones; Sulfoxides having sulfone or sulfoxide groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton
    • C07C317/32—Sulfones; Sulfoxides having sulfone or sulfoxide groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton with sulfone or sulfoxide groups bound to carbon atoms of six-membered aromatic rings of the carbon skeleton
DK91920162.4T 1990-10-25 1991-10-23 Fremgangsmåde til fremstilling af florfenicol, analoger heraf og oxazolinmellemprodukter dertil DK0555340T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US60357590A 1990-10-25 1990-10-25

Publications (1)

Publication Number Publication Date
DK0555340T3 true DK0555340T3 (da) 1995-03-06

Family

ID=24416027

Family Applications (1)

Application Number Title Priority Date Filing Date
DK91920162.4T DK0555340T3 (da) 1990-10-25 1991-10-23 Fremgangsmåde til fremstilling af florfenicol, analoger heraf og oxazolinmellemprodukter dertil

Country Status (19)

Country Link
US (1) US5382673A (da)
EP (1) EP0555340B1 (da)
JP (1) JPH0645580B2 (da)
KR (1) KR960008665B1 (da)
AT (1) ATE115123T1 (da)
AU (1) AU646910B2 (da)
CA (1) CA2094810C (da)
CZ (1) CZ286239B6 (da)
DE (1) DE69105752T2 (da)
DK (1) DK0555340T3 (da)
ES (1) ES2067958T3 (da)
GR (1) GR3015221T3 (da)
HK (1) HK185496A (da)
HU (2) HU212617B (da)
NZ (2) NZ250394A (da)
PL (1) PL166385B1 (da)
RU (1) RU2071468C1 (da)
SK (1) SK281740B6 (da)
WO (1) WO1992007824A1 (da)

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US7126005B2 (en) 2003-10-06 2006-10-24 Aurobindo Pharma Limited Process for preparing florfenicol
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US20070238700A1 (en) * 2006-04-10 2007-10-11 Winzenberg Kevin N N-phenyl-1,1,1-trifluoromethanesulfonamide hydrazone derivative compounds and their usage in controlling parasites
CN101605756A (zh) * 2006-12-13 2009-12-16 先灵-普劳有限公司 氟苯尼考及其类似物的水溶性前药
MX2009006467A (es) * 2006-12-13 2009-08-21 Schering Plough Ltd Profarmacos solubles en agua de cloranfenicol, tiamfenicol y analogos de los mismos.
US20090062397A1 (en) * 2007-04-27 2009-03-05 Schering-Plough Animal Health Corporation Compounds and methods for enhancing solubility of florfenicol and structurally-related antibiotics using cyclodextrins
TWI430995B (zh) 2007-06-26 2014-03-21 Du Pont 萘異唑啉無脊椎有害動物控制劑
KR101714291B1 (ko) 2007-06-27 2017-03-08 이 아이 듀폰 디 네모아 앤드 캄파니 동물 해충 방제 방법
US7550625B2 (en) * 2007-10-19 2009-06-23 Idexx Laboratories Esters of florfenicol
CN101909600A (zh) * 2007-11-09 2010-12-08 英特维特国际股份有限公司 速释固体制剂、其制备及其应用
TWI401023B (zh) 2008-02-06 2013-07-11 Du Pont 中離子農藥
KR20110038723A (ko) * 2008-07-30 2011-04-14 인터벳 인터내셔널 비.브이. 플로르페니콜에 대한 중간체로서 유용한 옥사졸린-보호된 아미노디올 화합물의 제조 방법
KR20120050467A (ko) 2009-08-05 2012-05-18 이 아이 듀폰 디 네모아 앤드 캄파니 메소이온성 살충제
MX2012001646A (es) 2009-08-05 2012-03-21 Du Pont Pesticidas mesoionicos.
UA107804C2 (en) 2009-08-05 2015-02-25 Du Pont Mixtures of pesticides mezoionnyh
UA110924C2 (uk) 2009-08-05 2016-03-10 Е. І. Дю Пон Де Немур Енд Компані Мезоіонні пестициди
BRPI1002023A2 (pt) 2010-03-01 2011-10-25 Nanocore Biotecnologia S A forma farmacêutica sólida de dissolução rápida para tratamento de infecções bacterianas
PL2576523T3 (pl) 2010-05-27 2016-08-31 Du Pont Krystaliczna postać 4-[5 - [3 -chloro-5 -(trifluorometylo)fenylo] -4,5 -dihydro-5 -(trifluorometylo)-3 - izoksazolilo]-n-[2-okso-2-[(2,2,2-trifluoroetylo)amino]etylo]-1- naftalenokarboksyamidu
WO2012087630A1 (en) 2010-12-20 2012-06-28 E.I. Du Pont De Nemours And Company Pyridine and pyrimidine compounds for controlling invertebrate
WO2013158422A1 (en) 2012-04-17 2013-10-24 E. I. Du Pont De Nemours And Company Heterocyclic compounds for controlling invertebrate pests
CN102911133B (zh) * 2012-10-31 2014-07-02 绍兴民生医药有限公司 (4r,5r)-2-二氯甲基-4,5-二氢-5-(4-甲砜基苯基)-4-恶唑甲醇的纯化方法
CN103980167B (zh) * 2014-04-17 2016-06-08 天津大学 一种无定形氟苯尼考及其制备方法
CN105218474B (zh) * 2015-10-22 2017-12-05 山东国邦药业股份有限公司 (4r,5r)‑2‑二氯甲基‑4,5‑二氢‑5‑(4‑甲砜基苯基)‑4‑恶唑甲醇的合成方法
CN106278964B (zh) * 2016-07-31 2018-01-16 浙江润康药业有限公司 氟苯尼考的制备方法
CN109678811B (zh) * 2019-01-25 2020-12-29 湖北中牧安达药业有限公司 一种氟苯尼考中间体环合物的不对称制备方法
CN110330463B (zh) * 2019-08-02 2021-05-14 山东国邦药业有限公司 一种氟苯尼考中间体的制备方法
CN113264892B (zh) * 2021-04-05 2022-12-20 复旦大学 一种使用微反应系统连续制备氟苯尼考关键中间体的方法
CN113185473B (zh) * 2021-06-30 2021-10-08 山东国邦药业有限公司 一种氟苯尼考中间体氟甲砜噁唑的制备方法
CN113185474B (zh) * 2021-07-02 2021-11-05 山东国邦药业有限公司 一种氟苯尼考中间体的制备方法

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Also Published As

Publication number Publication date
NZ240319A (en) 1994-10-26
HK185496A (en) 1996-10-11
PL166385B1 (en) 1995-05-31
CZ71093A3 (en) 1994-02-16
CA2094810C (en) 2002-06-04
HU9301182D0 (en) 1993-08-30
ATE115123T1 (de) 1994-12-15
WO1992007824A1 (en) 1992-05-14
CZ286239B6 (cs) 2000-02-16
JPH05507289A (ja) 1993-10-21
HU212617B (en) 1996-09-30
DE69105752T2 (de) 1995-05-11
GR3015221T3 (en) 1995-05-31
ES2067958T3 (es) 1995-04-01
AU8927991A (en) 1992-05-26
DE69105752D1 (de) 1995-01-19
AU646910B2 (en) 1994-03-10
NZ250394A (en) 1994-10-26
US5382673A (en) 1995-01-17
JPH0645580B2 (ja) 1994-06-15
RU2071468C1 (ru) 1997-01-10
HUT65402A (en) 1994-06-28
CA2094810A1 (en) 1992-04-26
EP0555340A1 (en) 1993-08-18
SK281740B6 (sk) 2001-07-10
SK37793A3 (en) 1993-10-06
KR960008665B1 (en) 1996-06-28
EP0555340B1 (en) 1994-12-07

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