IL101564A - Process for the preparation of a sterile powder comprising microcapsules suitable for use in ultrasound imaging and microcapsules obtained thereby - Google Patents

Process for the preparation of a sterile powder comprising microcapsules suitable for use in ultrasound imaging and microcapsules obtained thereby

Info

Publication number
IL101564A
IL101564A IL10156492A IL10156492A IL101564A IL 101564 A IL101564 A IL 101564A IL 10156492 A IL10156492 A IL 10156492A IL 10156492 A IL10156492 A IL 10156492A IL 101564 A IL101564 A IL 101564A
Authority
IL
Israel
Prior art keywords
microcapsules
process according
wall
protein
powder
Prior art date
Application number
IL10156492A
Other languages
English (en)
Other versions
IL101564A0 (en
Original Assignee
Andaris Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=10693031&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=IL101564(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Andaris Ltd filed Critical Andaris Ltd
Publication of IL101564A0 publication Critical patent/IL101564A0/xx
Publication of IL101564A publication Critical patent/IL101564A/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/22—Echographic preparations; Ultrasonic imaging preparations
    • A61K49/222—Echographic preparations; Ultrasonic imaging preparations characterised by a special physical form, e.g. emulsions, liposomes
    • A61K49/223—Microbubbles, hollow microspheres, free gas bubbles, gas microspheres
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/22—Echographic preparations; Ultrasonic imaging preparations
    • A61K49/222—Echographic preparations; Ultrasonic imaging preparations characterised by a special physical form, e.g. emulsions, liposomes
    • A61K49/225—Microparticles, microcapsules
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1682—Processes
    • A61K9/1688—Processes resulting in pure drug agglomerate optionally containing up to 5% of excipient
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1682—Processes
    • A61K9/1694—Processes resulting in granules or microspheres of the matrix type containing more than 5% of excipient
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5089—Processes
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J13/00—Colloid chemistry, e.g. the production of colloidal materials or their solutions, not otherwise provided for; Making microcapsules or microballoons
    • B01J13/02—Making microcapsules or microballoons
    • B01J13/04—Making microcapsules or microballoons by physical processes, e.g. drying, spraying
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J13/00—Colloid chemistry, e.g. the production of colloidal materials or their solutions, not otherwise provided for; Making microcapsules or microballoons
    • B01J13/02—Making microcapsules or microballoons
    • B01J13/04—Making microcapsules or microballoons by physical processes, e.g. drying, spraying
    • B01J13/043—Drying and spraying
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J13/00—Colloid chemistry, e.g. the production of colloidal materials or their solutions, not otherwise provided for; Making microcapsules or microballoons
    • B01J13/02—Making microcapsules or microballoons
    • B01J13/06—Making microcapsules or microballoons by phase separation
    • B01J13/14—Polymerisation; cross-linking
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S516/00—Colloid systems and wetting agents; subcombinations thereof; processes of
    • Y10S516/924—Significant dispersive or manipulative operation or step in making or stabilizing colloid system
    • Y10S516/928—Mixing combined with non-mixing operation or step, successively or simultaneously, e.g. heating, cooling, ph change, ageing, milling

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Dispersion Chemistry (AREA)
  • Acoustics & Sound (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Radiology & Medical Imaging (AREA)
  • Physics & Mathematics (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Manufacturing Of Micro-Capsules (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Compounds Of Unknown Constitution (AREA)
  • Ultra Sonic Daignosis Equipment (AREA)
  • Saccharide Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Ink Jet Recording Methods And Recording Media Thereof (AREA)
  • Separation Of Suspended Particles By Flocculating Agents (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
IL10156492A 1991-04-10 1992-04-10 Process for the preparation of a sterile powder comprising microcapsules suitable for use in ultrasound imaging and microcapsules obtained thereby IL101564A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB919107628A GB9107628D0 (en) 1991-04-10 1991-04-10 Preparation of diagnostic agents

Publications (2)

Publication Number Publication Date
IL101564A0 IL101564A0 (en) 1992-12-30
IL101564A true IL101564A (en) 1999-06-20

Family

ID=10693031

Family Applications (2)

Application Number Title Priority Date Filing Date
IL10156492A IL101564A (en) 1991-04-10 1992-04-10 Process for the preparation of a sterile powder comprising microcapsules suitable for use in ultrasound imaging and microcapsules obtained thereby
IL12303898A IL123038A0 (en) 1991-04-10 1998-01-23 Sterile hollow microcapsules

Family Applications After (1)

Application Number Title Priority Date Filing Date
IL12303898A IL123038A0 (en) 1991-04-10 1998-01-23 Sterile hollow microcapsules

Country Status (24)

Country Link
US (3) US5518709A (de)
EP (6) EP1829557A3 (de)
JP (2) JP2865866B2 (de)
KR (1) KR0129861B1 (de)
CN (1) CN1066977A (de)
AT (3) ATE194082T1 (de)
AU (2) AU655016B2 (de)
CA (1) CA2083260A1 (de)
DE (3) DE69233148T2 (de)
DK (3) DK0681843T3 (de)
ES (3) ES2150908T3 (de)
FI (1) FI925600A0 (de)
GB (2) GB9107628D0 (de)
GR (1) GR3034462T3 (de)
HK (1) HK1006538A1 (de)
HU (1) HUT62805A (de)
IE (1) IE921140A1 (de)
IL (2) IL101564A (de)
MX (1) MX9201694A (de)
NZ (1) NZ242328A (de)
PT (2) PT681843E (de)
RU (1) RU2109521C1 (de)
WO (1) WO1992018164A1 (de)
ZA (1) ZA922636B (de)

Families Citing this family (196)

* Cited by examiner, † Cited by third party
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HUT62805A (en) 1993-06-28
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FI925600A7 (fi) 1992-12-09
EP0972526B1 (de) 2005-03-09
HU9203891D0 (en) 1993-03-29
EP1547619A3 (de) 2008-07-02
HK1006538A1 (zh) 1999-03-05
ATE246519T1 (de) 2003-08-15
CA2083260A1 (en) 1992-10-11
EP0681843A3 (de) 1996-01-17
DK0972526T3 (da) 2005-06-27
EP0512693B1 (de) 2000-06-28
AU691196B2 (en) 1998-05-14
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ES2242355T3 (es) 2005-11-01
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JPH05507881A (ja) 1993-11-11
ATE194082T1 (de) 2000-07-15
US5518709A (en) 1996-05-21
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EP0681843A2 (de) 1995-11-15
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ATE290405T1 (de) 2005-03-15
IL123038A0 (en) 1998-09-24
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US6022525A (en) 2000-02-08
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