ES2052712T3 - Vector de levadura. - Google Patents

Vector de levadura.

Info

Publication number
ES2052712T3
ES2052712T3 ES88303157T ES88303157T ES2052712T3 ES 2052712 T3 ES2052712 T3 ES 2052712T3 ES 88303157 T ES88303157 T ES 88303157T ES 88303157 T ES88303157 T ES 88303157T ES 2052712 T3 ES2052712 T3 ES 2052712T3
Authority
ES
Spain
Prior art keywords
dna sequence
yeast
place
micron
yeast vector
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES88303157T
Other languages
English (en)
Inventor
Edward Hinchliffe
Simon Andrew Chinery
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Albumedix Ltd
Original Assignee
Delta Biotechnology Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB878708495A external-priority patent/GB8708495D0/en
Priority claimed from GB878718347A external-priority patent/GB8718347D0/en
Application filed by Delta Biotechnology Ltd filed Critical Delta Biotechnology Ltd
Application granted granted Critical
Publication of ES2052712T3 publication Critical patent/ES2052712T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/80—Vectors or expression systems specially adapted for eukaryotic hosts for fungi
    • C12N15/81—Vectors or expression systems specially adapted for eukaryotic hosts for fungi for yeasts

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Biomedical Technology (AREA)
  • Organic Chemistry (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Mycology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • Physics & Mathematics (AREA)
  • Plant Pathology (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)

Abstract

UN VECTOR PLAMSIDO DE 2 MICRAS PARA TRANSFORMAR LEVADURA, ESPECIALMENTE LEVADURA DE CERVEZA. COMPRENDE UNA SECUENCIA DE ADN QUE PERMITE LA PROPAGACION DEL PLASMIDO EN BACTERIAS, DOS COPIAS DE LUGAR DE RECOMBINACION FLP DE 74 PARES DE BASES DEL PLASMIDO DE 2 MICRAS EN ORIENTACION DIRECTA Y UNA SECUENCIA DE ADN QUE CODIFICA PARA UNA PROTEINA O UN PEPTIDO DE INTERES. ELPLASMIDO ESTA CONSTRUIDO DE TAL MANERA QUE EN LA LEVADURA LA SECUENCIA DE ADN BACTERIANA SE PIERDE ESPONTANEAMENTE. ES ACONSEJABLE INTRODUCIR EN EL LUGAR DE SNABI UN "GEN DE INTERES".
ES88303157T 1987-04-09 1988-04-08 Vector de levadura. Expired - Lifetime ES2052712T3 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB878708495A GB8708495D0 (en) 1987-04-09 1987-04-09 Yeast-disintegration vector
GB878718347A GB8718347D0 (en) 1987-08-03 1987-08-03 Yeast-disintegration vector

Publications (1)

Publication Number Publication Date
ES2052712T3 true ES2052712T3 (es) 1994-07-16

Family

ID=26292122

Family Applications (1)

Application Number Title Priority Date Filing Date
ES88303157T Expired - Lifetime ES2052712T3 (es) 1987-04-09 1988-04-08 Vector de levadura.

Country Status (13)

Country Link
US (1) US5637504A (es)
EP (1) EP0286424B1 (es)
JP (1) JP2873012B2 (es)
AU (1) AU613030B2 (es)
BR (1) BR8806573A (es)
CA (1) CA1339099C (es)
DE (1) DE3888381T2 (es)
ES (1) ES2052712T3 (es)
FI (1) FI95285C (es)
GB (1) GB2210621B (es)
HU (1) HU213344B (es)
IE (1) IE63424B1 (es)
WO (1) WO1988008027A1 (es)

Families Citing this family (42)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8615701D0 (en) * 1986-06-27 1986-08-06 Delta Biotechnology Ltd Stable gene integration vector
SG84484A1 (en) * 1991-02-25 2001-11-20 Ciba Geigy Ag Improved yeast vectors
US5993805A (en) * 1991-04-10 1999-11-30 Quadrant Healthcare (Uk) Limited Spray-dried microparticles and their use as therapeutic vehicles
GB9107628D0 (en) 1991-04-10 1991-05-29 Moonbrook Limited Preparation of diagnostic agents
FR2686899B1 (fr) * 1992-01-31 1995-09-01 Rhone Poulenc Rorer Sa Nouveaux polypeptides biologiquement actifs, leur preparation et compositions pharmaceutiques les contenant.
HUP0003541A3 (en) * 1997-09-05 2003-08-28 Pentapharm Ag Expression vector for improved production of polypeptides in yeast
US6358705B1 (en) 1998-07-16 2002-03-19 Novo Nordisk A/S Method of making proteins in transformed yeast cells
FR2784394B1 (fr) * 1998-10-09 2001-01-05 Lesaffre & Cie Cassette d'integration-excision
GB9902000D0 (en) 1999-01-30 1999-03-17 Delta Biotechnology Ltd Process
US20050100991A1 (en) * 2001-04-12 2005-05-12 Human Genome Sciences, Inc. Albumin fusion proteins
EP2275557A1 (en) * 2000-04-12 2011-01-19 Human Genome Sciences, Inc. Albumin fusion proteins
US6645767B1 (en) * 2000-10-03 2003-11-11 Carnegie Mellon University Cells engineered to contain genes of interest without expressed bacterial sequences and materials and methods therefor
US20050054051A1 (en) * 2001-04-12 2005-03-10 Human Genome Sciences, Inc. Albumin fusion proteins
US7507413B2 (en) * 2001-04-12 2009-03-24 Human Genome Sciences, Inc. Albumin fusion proteins
US7176278B2 (en) 2001-08-30 2007-02-13 Biorexis Technology, Inc. Modified transferrin fusion proteins
PT1463751E (pt) 2001-12-21 2013-08-26 Human Genome Sciences Inc Proteínas de fusão de albumina
AU2002364587A1 (en) * 2001-12-21 2003-07-30 Human Genome Sciences, Inc. Albumin fusion proteins
WO2005003296A2 (en) 2003-01-22 2005-01-13 Human Genome Sciences, Inc. Albumin fusion proteins
US20050222023A1 (en) * 2002-02-07 2005-10-06 Hans-Peter Hauser Albumin-fused kunitz domain peptides
KR20040089608A (ko) 2002-02-07 2004-10-21 델타 바이오테크놀로지 리미티드 Ｈｉｖ 억제 단백질
GB0217033D0 (en) 2002-07-23 2002-08-28 Delta Biotechnology Ltd Gene and polypeptide sequences
ATE539086T1 (de) * 2003-12-03 2012-01-15 Monika Kroez Interleukin-11-fusionsproteine
GB0329681D0 (en) * 2003-12-23 2004-01-28 Delta Biotechnology Ltd Gene expression technique
GB0329722D0 (en) * 2003-12-23 2004-01-28 Delta Biotechnology Ltd Modified plasmid and use thereof
CN102816241B (zh) * 2004-02-09 2015-07-22 人类基因科学公司 清蛋白融合蛋白
JP5631533B2 (ja) 2004-12-23 2014-11-26 ノボザイムス バイオファーマ デーコー アクティーゼルスカブ 遺伝子発現技術
MX2009001066A (es) 2006-07-24 2009-02-05 Biorexis Pharmaceutical Corp Proteinas de fusion de exendina.
CN101835801B (zh) 2007-08-08 2014-09-10 诺维信生物制药丹麦公司 转铁蛋白变体和偶联物
UA105201C2 (uk) * 2009-01-16 2014-04-25 Тева Фармасьютікал Індастріз Лтд. Застосування рекомбінантного альбуміну людини-гранулоцитарного колонієстимулюючого фактора людини для запобігання нейтропенії або лейкопенії
WO2010089385A1 (en) 2009-02-06 2010-08-12 Novozymes Biopharma Dk A/S Purification process
ES2630253T3 (es) 2009-02-11 2017-08-18 Albumedix A/S Variantes de albúmina y conjugados
CN102741280B (zh) 2009-10-30 2015-12-02 诺维信生物制药丹麦公司 白蛋白变体
JP5969458B2 (ja) 2010-04-09 2016-08-17 アルブミディクス アクティーゼルスカブ アルブミン誘導体及び変異体
CN110272484A (zh) 2011-05-05 2019-09-24 阿尔布梅迪克斯医疗有限公司 白蛋白变体
HU231053B1 (hu) * 2011-09-08 2020-03-30 Szegedi Tudományegyetem Rézrezisztens, fengicin hipertermelő Bacillus mojavensis törzs növényi kórokozók elleni védekezésre, alkalmazása és az ezt tartalmazó készítmények
WO2013075066A2 (en) 2011-11-18 2013-05-23 Eleven Biotherapeutics, Inc. Proteins with improved half-life and other properties
DK2825556T3 (en) 2012-03-16 2018-04-16 Albumedix As albumin Variants
WO2014072481A1 (en) 2012-11-08 2014-05-15 Novozymes Biopharma Dk A/S Albumin variants
WO2014147489A2 (en) 2013-03-15 2014-09-25 Teva Pharmaceutical Industries Ltd. Recombinant human albumin-human granulocyte colony stimulating factor for the prevention of neutropenia in pediatric patients
WO2017029407A1 (en) 2015-08-20 2017-02-23 Albumedix A/S Albumin variants and conjugates
JP2018093806A (ja) * 2016-12-14 2018-06-21 国立大学法人山口大学 酵母でタンパク質を過剰発現させる方法
CN112852860B (zh) * 2021-02-04 2023-04-28 天津大学 质粒载体及其在构建多拷贝表达系统中的应用

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4588684A (en) * 1983-04-26 1986-05-13 Chiron Corporation a-Factor and its processing signals
GB8334261D0 (en) * 1983-12-22 1984-02-01 Bass Plc Fermentation processes
GB8510219D0 (en) * 1985-04-22 1985-05-30 Bass Plc Isolation of fermentation products
IL80510A0 (en) * 1985-11-08 1987-02-27 Genetics Inst Improved yeast strains
GB8615701D0 (en) * 1986-06-27 1986-08-06 Delta Biotechnology Ltd Stable gene integration vector
AU8171087A (en) * 1986-10-27 1988-05-25 Whitehead Institute For Biomedical Research Gene amplification using retrotransposons
ES2052062T3 (es) * 1988-06-11 1994-07-01 Ciba Geigy Ag Nuevos polipeptidos con actividad anticoagulante.

Also Published As

Publication number Publication date
WO1988008027A1 (en) 1988-10-20
GB8828753D0 (en) 1989-02-01
HUT52560A (en) 1990-07-28
JPH01503275A (ja) 1989-11-09
FI95285B (fi) 1995-09-29
EP0286424A1 (en) 1988-10-12
DE3888381D1 (de) 1994-04-21
IE881046L (en) 1988-10-09
IE63424B1 (en) 1995-04-19
BR8806573A (pt) 1989-10-31
JP2873012B2 (ja) 1999-03-24
FI885705A0 (fi) 1988-12-08
US5637504A (en) 1997-06-10
HU213344B (en) 1997-05-28
FI885705A (fi) 1988-12-08
FI95285C (fi) 1996-01-10
AU613030B2 (en) 1991-07-25
GB2210621B (en) 1990-11-21
EP0286424B1 (en) 1994-03-16
AU1540388A (en) 1988-11-04
CA1339099C (en) 1997-07-29
GB2210621A (en) 1989-06-14
DE3888381T2 (de) 1994-07-28

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