ATE290405T1 - Verfahren zur herstellung von diagnostica - Google Patents
Verfahren zur herstellung von diagnosticaInfo
- Publication number
- ATE290405T1 ATE290405T1 AT99203198T AT99203198T ATE290405T1 AT E290405 T1 ATE290405 T1 AT E290405T1 AT 99203198 T AT99203198 T AT 99203198T AT 99203198 T AT99203198 T AT 99203198T AT E290405 T1 ATE290405 T1 AT E290405T1
- Authority
- AT
- Austria
- Prior art keywords
- microcapsules
- wall
- forming material
- diagnostica
- producing
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K49/00—Preparations for testing in vivo
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K49/00—Preparations for testing in vivo
- A61K49/22—Echographic preparations; Ultrasonic imaging preparations
- A61K49/222—Echographic preparations; Ultrasonic imaging preparations characterised by a special physical form, e.g. emulsions, liposomes
- A61K49/223—Microbubbles, hollow microspheres, free gas bubbles, gas microspheres
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K49/00—Preparations for testing in vivo
- A61K49/22—Echographic preparations; Ultrasonic imaging preparations
- A61K49/222—Echographic preparations; Ultrasonic imaging preparations characterised by a special physical form, e.g. emulsions, liposomes
- A61K49/225—Microparticles, microcapsules
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1682—Processes
- A61K9/1688—Processes resulting in pure drug agglomerate optionally containing up to 5% of excipient
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1682—Processes
- A61K9/1694—Processes resulting in granules or microspheres of the matrix type containing more than 5% of excipient
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5089—Processes
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J13/00—Colloid chemistry, e.g. the production of colloidal materials or their solutions, not otherwise provided for; Making microcapsules or microballoons
- B01J13/02—Making microcapsules or microballoons
- B01J13/04—Making microcapsules or microballoons by physical processes, e.g. drying, spraying
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J13/00—Colloid chemistry, e.g. the production of colloidal materials or their solutions, not otherwise provided for; Making microcapsules or microballoons
- B01J13/02—Making microcapsules or microballoons
- B01J13/04—Making microcapsules or microballoons by physical processes, e.g. drying, spraying
- B01J13/043—Drying and spraying
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J13/00—Colloid chemistry, e.g. the production of colloidal materials or their solutions, not otherwise provided for; Making microcapsules or microballoons
- B01J13/02—Making microcapsules or microballoons
- B01J13/06—Making microcapsules or microballoons by phase separation
- B01J13/14—Polymerisation; cross-linking
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S516/00—Colloid systems and wetting agents; subcombinations thereof; processes of
- Y10S516/924—Significant dispersive or manipulative operation or step in making or stabilizing colloid system
- Y10S516/928—Mixing combined with non-mixing operation or step, successively or simultaneously, e.g. heating, cooling, ph change, ageing, milling
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Dispersion Chemistry (AREA)
- Acoustics & Sound (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Radiology & Medical Imaging (AREA)
- Physics & Mathematics (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Manufacturing Of Micro-Capsules (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Compounds Of Unknown Constitution (AREA)
- Ultra Sonic Daignosis Equipment (AREA)
- Saccharide Compounds (AREA)
- Hydrogenated Pyridines (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Ink Jet Recording Methods And Recording Media Thereof (AREA)
- Separation Of Suspended Particles By Flocculating Agents (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB919107628A GB9107628D0 (en) | 1991-04-10 | 1991-04-10 | Preparation of diagnostic agents |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE290405T1 true ATE290405T1 (de) | 2005-03-15 |
Family
ID=10693031
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT92303236T ATE194082T1 (de) | 1991-04-10 | 1992-04-10 | Verfahren zur herstellung diagnostischer mittel |
| AT95110723T ATE246519T1 (de) | 1991-04-10 | 1992-04-10 | Verfahren zur herstellung von diagnostischen mitteln |
| AT99203198T ATE290405T1 (de) | 1991-04-10 | 1992-04-10 | Verfahren zur herstellung von diagnostica |
Family Applications Before (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT92303236T ATE194082T1 (de) | 1991-04-10 | 1992-04-10 | Verfahren zur herstellung diagnostischer mittel |
| AT95110723T ATE246519T1 (de) | 1991-04-10 | 1992-04-10 | Verfahren zur herstellung von diagnostischen mitteln |
Country Status (24)
| Country | Link |
|---|---|
| US (3) | US5518709A (de) |
| EP (6) | EP1829557A3 (de) |
| JP (2) | JP2865866B2 (de) |
| KR (1) | KR0129861B1 (de) |
| CN (1) | CN1066977A (de) |
| AT (3) | ATE194082T1 (de) |
| AU (2) | AU655016B2 (de) |
| CA (1) | CA2083260A1 (de) |
| DE (3) | DE69233148T2 (de) |
| DK (3) | DK0681843T3 (de) |
| ES (3) | ES2150908T3 (de) |
| FI (1) | FI925600A0 (de) |
| GB (2) | GB9107628D0 (de) |
| GR (1) | GR3034462T3 (de) |
| HK (1) | HK1006538A1 (de) |
| HU (1) | HUT62805A (de) |
| IE (1) | IE921140A1 (de) |
| IL (2) | IL101564A (de) |
| MX (1) | MX9201694A (de) |
| NZ (1) | NZ242328A (de) |
| PT (2) | PT681843E (de) |
| RU (1) | RU2109521C1 (de) |
| WO (1) | WO1992018164A1 (de) |
| ZA (1) | ZA922636B (de) |
Families Citing this family (196)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6613306B1 (en) | 1990-04-02 | 2003-09-02 | Bracco International B.V. | Ultrasound contrast agents and methods of making and using them |
| US7083778B2 (en) | 1991-05-03 | 2006-08-01 | Bracco International B.V. | Ultrasound contrast agents and methods of making and using them |
| IN172208B (de) * | 1990-04-02 | 1993-05-01 | Sint Sa | |
| US5445813A (en) | 1992-11-02 | 1995-08-29 | Bracco International B.V. | Stable microbubble suspensions as enhancement agents for ultrasound echography |
| US6989141B2 (en) | 1990-05-18 | 2006-01-24 | Bracco International B.V. | Ultrasound contrast agents and methods of making and using them |
| USRE39146E1 (en) | 1990-04-02 | 2006-06-27 | Bracco International B.V. | Long-lasting aqueous dispersions or suspensions of pressure-resistant gas-filled microvesicles and methods for the preparation thereof |
| US6391343B1 (en) | 1991-01-15 | 2002-05-21 | Hemosphere, Inc. | Fibrinogen-coated particles for therapeutic use |
| GB9107628D0 (en) | 1991-04-10 | 1991-05-29 | Moonbrook Limited | Preparation of diagnostic agents |
| US5993805A (en) | 1991-04-10 | 1999-11-30 | Quadrant Healthcare (Uk) Limited | Spray-dried microparticles and their use as therapeutic vehicles |
| IL104084A (en) | 1992-01-24 | 1996-09-12 | Bracco Int Bv | Long-lasting aqueous suspensions of pressure-resistant gas-filled microvesicles their preparation and contrast agents consisting of them |
| US6582728B1 (en) | 1992-07-08 | 2003-06-24 | Inhale Therapeutic Systems, Inc. | Spray drying of macromolecules to produce inhaleable dry powders |
| DK0679088T3 (da) * | 1992-09-29 | 2002-10-28 | Inhale Therapeutic Syst | Pulmonal levering af aktive fragmenter af parathyreoideaea hormon |
| GB9221329D0 (en) * | 1992-10-10 | 1992-11-25 | Delta Biotechnology Ltd | Preparation of further diagnostic agents |
| US7425543B2 (en) * | 1992-11-16 | 2008-09-16 | The Corporation Of Mercer University | Microencapsulated materials and method of making same |
| US6428844B1 (en) * | 1993-02-03 | 2002-08-06 | Rohm And Haas Company | Reduction of microfoam in a spray-applied waterborne composition |
| PL312387A1 (en) * | 1993-07-02 | 1996-04-15 | Molecular Biosystems Inc | Proteinous microbeads of encapsulated non-dissolving gas and method of making them and their application as ultrasonic visualisation medium |
| ES2231775T5 (es) † | 1993-07-30 | 2011-02-02 | Imcor Pharmaceutical Co. | Composición de microburbujas estabilizadas para ecografía. |
| PL182223B1 (pl) | 1993-12-15 | 2001-11-30 | Bracco Research Sa | Biokompatybilna faza rozproszona do otrzymywania srodka kontrastowego do badan ultradzwiekowych, srodek kontrastowy do badan ultradzwiekowych, suchy preparat srodka kontrastowego oraz dwuskladnikowy zestaw do otrzymywania srodka kontrastowego do badan ultradzwiekowych PL PL PL |
| DE69535897D1 (de) | 1994-03-07 | 2009-01-22 | Nektar Therapeutics | Verfahren und Zusammensetzung für die pulmonale Darreichung von Insulin |
| US20030113273A1 (en) * | 1996-06-17 | 2003-06-19 | Patton John S. | Methods and compositions for pulmonary delivery of insulin |
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| US5674468A (en) * | 1992-03-06 | 1997-10-07 | Nycomed Imaging As | Contrast agents comprising gas-containing or gas-generating polymer microparticles or microballoons |
| EP0611567B1 (de) * | 1992-06-12 | 2002-08-28 | Teijin Limited | Ultrafeines pulver zur inhalation und dessen herstellung |
| WO1993025193A1 (fr) * | 1992-06-12 | 1993-12-23 | Teijin Limited | Preparation pharmaceutique destinee a etre administree par les voies respiratoires |
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| GB9221329D0 (en) | 1992-10-10 | 1992-11-25 | Delta Biotechnology Ltd | Preparation of further diagnostic agents |
| GB9423419D0 (en) | 1994-11-19 | 1995-01-11 | Andaris Ltd | Preparation of hollow microcapsules |
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| US6017310A (en) | 1996-09-07 | 2000-01-25 | Andaris Limited | Use of hollow microcapsules |
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-
1991
- 1991-04-10 GB GB919107628A patent/GB9107628D0/en active Pending
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1992
- 1992-04-09 IE IE114092A patent/IE921140A1/en unknown
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- 1992-04-10 EP EP07075443A patent/EP1829557A3/de not_active Withdrawn
- 1992-04-10 ES ES92303236T patent/ES2150908T3/es not_active Expired - Lifetime
- 1992-04-10 CA CA002083260A patent/CA2083260A1/en not_active Abandoned
- 1992-04-10 PT PT95110723T patent/PT681843E/pt unknown
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- 1992-04-10 ES ES99203198T patent/ES2242355T3/es not_active Expired - Lifetime
- 1992-04-10 DK DK95110723T patent/DK0681843T3/da active
- 1992-04-10 AT AT95110723T patent/ATE246519T1/de not_active IP Right Cessation
- 1992-04-10 US US07/956,875 patent/US5518709A/en not_active Expired - Lifetime
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- 1992-04-10 FI FI925600A patent/FI925600A0/fi unknown
- 1992-04-10 EP EP05075544A patent/EP1547619A3/de not_active Withdrawn
- 1992-04-10 IL IL10156492A patent/IL101564A/en not_active IP Right Cessation
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- 1992-04-10 CN CN92103376A patent/CN1066977A/zh active Pending
- 1992-04-10 PT PT92303236T patent/PT512693E/pt unknown
- 1992-04-10 KR KR1019920703116A patent/KR0129861B1/ko not_active Expired - Fee Related
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- 1992-04-10 DK DK99203198T patent/DK0972526T3/da active
- 1992-04-10 EP EP99203198A patent/EP0972526B1/de not_active Revoked
- 1992-04-10 HU HU9203891A patent/HUT62805A/hu unknown
- 1992-04-10 EP EP92908598A patent/EP0533886A1/de active Pending
- 1992-04-10 WO PCT/GB1992/000643 patent/WO1992018164A1/en not_active Ceased
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1994
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1995
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1998
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1999
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2000
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