HUP0003743A2 - Rezorcin-származékokat tartalmazó topikális gyógyászati készítmény és ennek alkalmazása embernél bőr színtelenítésére vagy bőr pigmentációjának csökkentésére - Google Patents

Rezorcin-származékokat tartalmazó topikális gyógyászati készítmény és ennek alkalmazása embernél bőr színtelenítésére vagy bőr pigmentációjának csökkentésére

Info

Publication number
HUP0003743A2
HUP0003743A2 HU0003743A HUP0003743A HUP0003743A2 HU P0003743 A2 HUP0003743 A2 HU P0003743A2 HU 0003743 A HU0003743 A HU 0003743A HU P0003743 A HUP0003743 A HU P0003743A HU P0003743 A2 HUP0003743 A2 HU P0003743A2
Authority
HU
Hungary
Prior art keywords
carbon atoms
group containing
skin
general formula
alkyl
Prior art date
Application number
HU0003743A
Other languages
English (en)
Inventor
Lan Hu
Original Assignee
Pfizer Products Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Products Inc. filed Critical Pfizer Products Inc.
Publication of HUP0003743A2 publication Critical patent/HUP0003743A2/hu
Publication of HUP0003743A3 publication Critical patent/HUP0003743A3/hu

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • A61Q19/02—Preparations for care of the skin for chemically bleaching or whitening the skin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/19—Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
    • A61K8/25—Silicon; Compounds thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/34—Alcohols
    • A61K8/347—Phenols
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/36—Carboxylic acids; Salts or anhydrides thereof
    • A61K8/365—Hydroxycarboxylic acids; Ketocarboxylic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/37—Esters of carboxylic acids
    • A61K8/375—Esters of carboxylic acids the alcohol moiety containing more than one hydroxy group
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/40—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
    • A61K8/41—Amines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/46—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing sulfur
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/67—Vitamins
    • A61K8/671—Vitamin A; Derivatives thereof, e.g. ester of vitamin A acid, ester of retinol, retinol, retinal
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/06—Antipsoriatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/10—Anti-acne agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/16—Emollients or protectives, e.g. against radiation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • A61Q19/10—Washing or bathing preparations
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/74—Biological properties of particular ingredients
    • A61K2800/78—Enzyme modulators, e.g. Enzyme agonists
    • A61K2800/782—Enzyme inhibitors; Enzyme antagonists
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S977/00—Nanotechnology
    • Y10S977/902—Specified use of nanostructure
    • Y10S977/904—Specified use of nanostructure for medical, immunological, body treatment, or diagnosis
    • Y10S977/915—Therapeutic or pharmaceutical composition
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S977/00—Nanotechnology
    • Y10S977/902—Specified use of nanostructure
    • Y10S977/904—Specified use of nanostructure for medical, immunological, body treatment, or diagnosis
    • Y10S977/926—Topical chemical, e.g. cosmetic or sunscreen

Abstract

A találmány szerinti készítmény hatásos mennyiségben valamely (I)általános képletű vegyületet - a képletben X jelentése hidrogénatom; OR1 általános képletű csoport, ahol R1jelentése hidrogénatom vagy 1-6 szénatomot tartalmazó alkil- vagy azalkilrészben 1-6 szénatomot tartalmazó aralkilcsoport; OCOR2 általánosképletű csoport, ahol R2 jelentése 1-6 szénatomot tartalmazó alkil-,az alkilrészben 1-6 szénatomot tartalmazó aralkil- vagy fenilcsoport;halogénatom; 1-6 szénatomot tartalmazó alkilcsoport; az alkilrészben1-6 szénatomot tartalmazó aralkilcsoport; SR3 általános képletűcsoport, ahol R3 jelentése hidrogénatom vagy 1-6 szénatomot tartalmazóalkil- vagy az alkilrészben 1-6 szénatomot tartalmazó aralkilcsoport;vagy NHR1 általános képletű csoport, ahol R1 jelentése a korábbanmegadott; n értéke 0, 1, 2 vagy 3; és a szaggatott vonal az adott helyzetbenadott esetben jelen lévő kettős kötést jelenti - vagy ennekgyógyászatilag elfogadható sóját tartalmazza a gyógyszergyártásbanszokásosan használt hordozó- és/vagy egyéb segédanyagokkal együtt. Ó
HU0003743A 1997-09-23 1998-09-21 Topical pharmaceutical composition containing resorcinol derivatives and its use for lightening skin or reducing the pigmentation of skin in a human HUP0003743A3 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US5962597P 1997-09-23 1997-09-23
PCT/IB1998/001451 WO1999015148A1 (en) 1997-09-23 1998-09-21 Resorcinol derivatives

Publications (2)

Publication Number Publication Date
HUP0003743A2 true HUP0003743A2 (hu) 2001-04-28
HUP0003743A3 HUP0003743A3 (en) 2006-02-28

Family

ID=22024176

Family Applications (1)

Application Number Title Priority Date Filing Date
HU0003743A HUP0003743A3 (en) 1997-09-23 1998-09-21 Topical pharmaceutical composition containing resorcinol derivatives and its use for lightening skin or reducing the pigmentation of skin in a human

Country Status (46)

Country Link
US (1) US6132740A (hu)
EP (1) EP0904774B1 (hu)
JP (2) JP3591763B2 (hu)
KR (1) KR100373996B1 (hu)
CN (1) CN1176647C (hu)
AP (1) AP857A (hu)
AR (1) AR012520A1 (hu)
AT (1) ATE235220T1 (hu)
AU (1) AU735716C (hu)
BG (1) BG64524B1 (hu)
BR (1) BR9803596A (hu)
CA (1) CA2247748C (hu)
CO (1) CO5070677A1 (hu)
CZ (1) CZ297669B6 (hu)
DE (1) DE69812519T2 (hu)
DK (1) DK0904774T3 (hu)
DZ (1) DZ2614A1 (hu)
EA (1) EA003576B1 (hu)
EG (1) EG23860A (hu)
ES (1) ES2192301T3 (hu)
GT (1) GT199800150A (hu)
HK (1) HK1028344A1 (hu)
HR (1) HRP20000168B1 (hu)
HU (1) HUP0003743A3 (hu)
ID (1) ID24084A (hu)
IL (2) IL134598A0 (hu)
IS (1) IS2280B (hu)
MA (1) MA26548A1 (hu)
MY (1) MY117805A (hu)
NO (1) NO327177B1 (hu)
NZ (1) NZ502797A (hu)
OA (1) OA11334A (hu)
PA (1) PA8459901A1 (hu)
PE (1) PE117299A1 (hu)
PL (1) PL195192B1 (hu)
PT (1) PT904774E (hu)
SA (1) SA98190724B1 (hu)
SI (1) SI0904774T1 (hu)
SK (1) SK284983B6 (hu)
TN (1) TNSN98176A1 (hu)
TR (1) TR200000782T2 (hu)
TW (1) TW585780B (hu)
UA (1) UA57106C2 (hu)
UY (2) UY25191A1 (hu)
WO (1) WO1999015148A1 (hu)
ZA (1) ZA988669B (hu)

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