HUE028501T2 - 4-[5-[3-klór-5-(trifluormetil)fenil]-4,5-dihidro-5-(trifluormetil)-3-izoxazolil]-N-[2-oxo -2-[(2,2,2-trifluoretil)amino]etil]-1-naftalinkarboxamid krisztallin alakja - Google Patents

4-[5-[3-klór-5-(trifluormetil)fenil]-4,5-dihidro-5-(trifluormetil)-3-izoxazolil]-N-[2-oxo -2-[(2,2,2-trifluoretil)amino]etil]-1-naftalinkarboxamid krisztallin alakja Download PDF

Info

Publication number
HUE028501T2
HUE028501T2 HUE11727834A HUE11727834A HUE028501T2 HU E028501 T2 HUE028501 T2 HU E028501T2 HU E11727834 A HUE11727834 A HU E11727834A HU E11727834 A HUE11727834 A HU E11727834A HU E028501 T2 HUE028501 T2 HU E028501T2
Authority
HU
Hungary
Prior art keywords
compound
solid
spp
animal
polymorph
Prior art date
Application number
HUE11727834A
Other languages
English (en)
Inventor
Martin James Currie
Original Assignee
Du Pont
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Du Pont filed Critical Du Pont
Publication of HUE028501T2 publication Critical patent/HUE028501T2/hu

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D261/00—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings
    • C07D261/02—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings
    • C07D261/04—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N25/00—Biocides, pest repellants or attractants, or plant growth regulators, characterised by their forms, or by their non-active ingredients or by their methods of application, e.g. seed treatment or sequential application; Substances for reducing the noxious effect of the active ingredients to organisms other than pests
    • A01N25/12—Powders or granules
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
    • A01N43/72—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with nitrogen atoms and oxygen or sulfur atoms as ring hetero atoms
    • A01N43/80—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with nitrogen atoms and oxygen or sulfur atoms as ring hetero atoms five-membered rings with one nitrogen atom and either one oxygen atom or one sulfur atom in positions 1,2
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/42—Oxazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/10—Anthelmintics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/14—Ectoparasiticides, e.g. scabicides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00—Indexing scheme relating to specific properties of organic compounds
    • C07B2200/13—Crystalline forms, e.g. polymorphs

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Environmental Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Dentistry (AREA)
  • Agronomy & Crop Science (AREA)
  • Pest Control & Pesticides (AREA)
  • Plant Pathology (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Epidemiology (AREA)
  • Toxicology (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)

Claims (3)

  1. Szabadalmi Igénygpptpk 1. 4^5»p.kíór~5 -(öí fi«ormetíl)feni1] -4.5'djh}4ro^5^|H||^pme^i^*i20xs20Îii|-/^2^ô~2-K2.2»2-tnlleoret!})amín8jetrt}' i -«albltakarkoxaroid tenu»!®. polimorfja, akba! jeielmezve, Intgy » por röntge» 5 dhbakciós mintának legalább a 28 reflexi« helyei m: 57.433 !S,5M: 20.. 287 20.. 785 25,4! 22,5 52 23,502 24,507 27,444
  2. 2. KonnmzjbiÔ, amely rnAülatázás ax 5. igénypont wrtntl pimorlot «fs egv további kômpôeOsf, amply tó vm válásaivá: a fevmkezôkboi siló csopofibél::: szurtbktmtpk, ssÄd 5%Mszemk: és iolyélony bigMszemk, » kompomem opfclonaliisan továbbá: itSÄskx legalább egy tovább! bíologiailág aktív: yegyülsítét víigy Sáé!! 50: 3. Kk^pOakdo áiilát védőimére gérincteíeo parazita kérte vilii, sníeiy tamtaaazsa az- !.. igénypont szorító poHníórrpsíazítleiáoson hatásos ánmoyiségéí és legalább egy iordoartasyagöL 4. A 3 .igénypont szerinti kmmóafeiö orälM adagolási förtolbam S:, Eljárás germóíeisn kártevő éikm, amely tartalmazza: a pÉimsien kártevő vagy környezete Mstkékésbe MKásst: m I igénypont: szerinti polimorf blolögíáiiág bátásös mennyiségével, azzal a II MíéteBel hogy la« égarasinam emberi vagy Alt tépi terápiás kezelést eljárása, lb. As 5,. igénypont szerinti eíjáíás, alsói a környezet egy .növény,
  3. 3. Az I, igénypont szerinti polimorf feilmsználásra gíaioételé«. kártevők leküzdéséit
HUE11727834A 2010-05-27 2011-05-19 4-[5-[3-klór-5-(trifluormetil)fenil]-4,5-dihidro-5-(trifluormetil)-3-izoxazolil]-N-[2-oxo -2-[(2,2,2-trifluoretil)amino]etil]-1-naftalinkarboxamid krisztallin alakja HUE028501T2 (hu)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US34895810P 2010-05-27 2010-05-27

Publications (1)

Publication Number Publication Date
HUE028501T2 true HUE028501T2 (hu) 2016-12-28

Family

ID=44359642

Family Applications (1)

Application Number Title Priority Date Filing Date
HUE11727834A HUE028501T2 (hu) 2010-05-27 2011-05-19 4-[5-[3-klór-5-(trifluormetil)fenil]-4,5-dihidro-5-(trifluormetil)-3-izoxazolil]-N-[2-oxo -2-[(2,2,2-trifluoretil)amino]etil]-1-naftalinkarboxamid krisztallin alakja

Country Status (30)

Country Link
US (1) US8598087B2 (hu)
EP (1) EP2576523B1 (hu)
JP (1) JP5933530B2 (hu)
KR (3) KR20130124458A (hu)
CN (1) CN102947278B (hu)
AR (2) AR081226A1 (hu)
AU (1) AU2011258621B2 (hu)
BR (1) BR112012030151B8 (hu)
CA (1) CA2799963C (hu)
CL (1) CL2012003272A1 (hu)
DK (1) DK2576523T3 (hu)
ES (1) ES2566402T3 (hu)
GT (1) GT201200316A (hu)
HK (1) HK1183875A1 (hu)
HR (1) HRP20160355T1 (hu)
HU (1) HUE028501T2 (hu)
IL (1) IL223002A (hu)
MA (1) MA34247B1 (hu)
MD (1) MD4363C1 (hu)
MX (1) MX2012013758A (hu)
MY (1) MY156670A (hu)
NZ (1) NZ603584A (hu)
PL (1) PL2576523T3 (hu)
RS (1) RS54677B1 (hu)
SI (1) SI2576523T1 (hu)
TN (1) TN2012000557A1 (hu)
UA (1) UA108881C2 (hu)
UY (1) UY33397A (hu)
WO (1) WO2011149749A1 (hu)
ZA (1) ZA201208760B (hu)

Families Citing this family (42)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TWI487486B (zh) 2009-12-01 2015-06-11 Syngenta Participations Ag 以異唑啉衍生物為主之殺蟲化合物
CA2848317C (en) * 2011-09-12 2021-01-19 Merial Limited Parasiticidal compositions comprising an isoxazoline active agent, methods and uses thereof.
AU2013217633B2 (en) * 2012-02-06 2017-01-12 Boehringer Ingelheim Animal Health USA Inc. Parasiticidal oral veterinary compositions comprising systemically-acting active agents, methods and uses thereof
AU2013245011B2 (en) 2012-04-04 2017-11-23 Intervet International B.V. Solid oral pharmaceutical compositions for isoxazoline compounds
WO2014053407A1 (en) 2012-10-01 2014-04-10 Basf Se N-thio-anthranilamide compounds and their use as pesticides
AR094139A1 (es) 2012-10-01 2015-07-15 Basf Se Mezclas activas como plaguicidas, que comprenden compuestos de antranilamida
JP2015532274A (ja) 2012-10-01 2015-11-09 ビーエーエスエフ ソシエタス・ヨーロピアＢａｓｆ Ｓｅ 栽培植物へのｎ−チオ−アントラニルアミド化合物の使用
WO2014053406A1 (en) 2012-10-01 2014-04-10 Basf Se Method of controlling ryanodine-modulator insecticide resistant insects
WO2014053401A2 (en) 2012-10-01 2014-04-10 Basf Se Method of improving plant health
CN104768377A (zh) 2012-10-01 2015-07-08 巴斯夫欧洲公司 包含邻氨基苯甲酰胺类化合物的农药活性混合物
WO2014053403A1 (en) 2012-10-01 2014-04-10 Basf Se Method of controlling insecticide resistant insects
US9532946B2 (en) * 2012-11-20 2017-01-03 Intervet Inc. Manufacturing of semi-plastic pharmaceutical dosage units
WO2014079820A1 (en) 2012-11-22 2014-05-30 Basf Se Use of anthranilamide compounds for reducing insect-vectored viral infections
JP2016501264A (ja) 2012-12-14 2016-01-18 ビーエーエスエフ ソシエタス・ヨーロピアＢａｓｆ Ｓｅ 動物有害生物を防除するためのマロノニトリル化合物
US20150368236A1 (en) 2012-12-27 2015-12-24 Basf Se 2-(pyridin-3-yl)-5-hetaryl-thiazole compounds carrying an imine or imine-derived substituent for combating invertebrate pests
SI2953942T1 (en) 2013-02-06 2018-03-30 Bayer Cropscience Ag Halogen-substituted pyrazole derivatives such as pesticides
CN105121416B (zh) * 2013-02-14 2018-12-04 日产化学工业株式会社 异噁唑啉取代苯甲酰胺化合物的结晶性多晶型物及其制造方法
BR112015023435B1 (pt) 2013-03-15 2022-05-03 Douglas Robert Cleverly Formulação mastigável estável sob armazenagem e método de fabricação de uma formulação mastigável, palatável e estável sob armazenagem
US20160050923A1 (en) 2013-04-19 2016-02-25 Basf Se N-substituted acyl-imino-pyridine compounds and derivatives for combating animal pests
BR112015031439A2 (pt) 2013-06-21 2017-07-25 Basf Se métodos para o combate ou controle das pragas, para o tratamento, prevenção e proteção de culturas de soja, para o controle e proteção do material de propagação dos vegetais de soja, para o combate ou controle das pragas e utilização de um composto de fórmula i
AR097138A1 (es) 2013-07-15 2016-02-24 Basf Se Compuestos plaguicidas
CA2922506A1 (en) 2013-09-19 2015-03-26 Basf Se N-acylimino heterocyclic compounds
WO2015055497A1 (en) 2013-10-16 2015-04-23 Basf Se Substituted pesticidal pyrazole compounds
WO2015055757A1 (en) 2013-10-18 2015-04-23 Basf Se Use of pesticidal active carboxamide derivative in soil and seed application and treatment methods
US20160318897A1 (en) 2013-12-18 2016-11-03 Basf Se Azole compounds carrying an imine-derived substituent
EP3083581A1 (en) 2013-12-18 2016-10-26 Basf Se N-substituted imino heterocyclic compounds
ES2683693T3 (es) 2014-01-03 2018-09-27 Bayer Animal Health Gmbh Nuevas pirazolil-heteroarilamidas como agentes plaguicidas
WO2015104422A1 (en) 2014-01-13 2015-07-16 Basf Se Dihydrothiophene compounds for controlling invertebrate pests
WO2016008830A1 (de) 2014-07-15 2016-01-21 Bayer Cropscience Aktiengesellschaft Aryl-triazolyl-pyridine als schädlingsbekämpfungsmittel
UY36570A (es) * 2015-02-26 2016-10-31 Merial Inc Formulaciones inyectables de acción prolongada que comprenden un agente activo isoxazolina, métodos y usos de las mismas
CN108055825B (zh) 2015-04-08 2021-03-30 勃林格殷格翰动物保健美国公司 包含异噁唑啉活性剂的延长释放可注射制剂、其方法和用途
UY37137A (es) 2016-02-24 2017-09-29 Merial Inc Compuestos antiparasitarios de isoxazolina, formulaciones inyectables de acción prolongada que los comprenden, métodos y usos de los mismos
WO2018039508A1 (en) 2016-08-25 2018-03-01 Merial, Inc. Method for reducing unwanted effects in parasiticidal treatments
AU2017344097A1 (en) 2016-10-14 2019-05-02 Boehringer Ingelheim Animal Health USA Inc. Pesticidal and parasiticidal vinyl isoxazoline compounds
MX2019011931A (es) 2017-04-05 2020-01-13 Boehringer Ingelheim Animal Health Usa Inc Formas cristalinas de (s)-afoxolaner.
KR101988442B1 (ko) * 2017-06-30 2019-06-12 주식회사 삼양사 결정형 기능성 감미료
US11589586B2 (en) 2017-08-14 2023-02-28 Boehringer Ingelheim Animal Health USA Inc. Pesticidal and parasiticidal pyrazole-isoxazoline compounds
UA127456C2 (uk) * 2017-11-07 2023-08-30 Інтервет Інтернешнл Б.В. Ін'єкційна ізоксазолінова фармацевтична композиція та її застосування
EP3707129A1 (en) * 2017-11-07 2020-09-16 Intervet International B.V. Process for preparing large size isoxazoline particles
WO2021242481A1 (en) 2020-05-28 2021-12-02 Boehringer Ingelheim Animal Health USA Inc. Bi-modal release intra-ruminal capsule device and methods of use thereof
WO2021254445A1 (zh) * 2020-06-19 2021-12-23 东莞市东阳光仿制药研发有限公司 一种gaba抑制剂的晶型及其制备方法
EP4262789A1 (en) * 2020-12-21 2023-10-25 Boehringer Ingelheim Vetmedica GmbH Parasiticidal collar comprising isoxazoline compounds

Family Cites Families (96)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US1815604A (en) 1922-10-31 1931-07-21 Winthrop Chem Co Organic mercury compound
US1679404A (en) 1926-02-04 1928-08-07 Rockwood Sprinkler Co Massachusetts Constant-alarm device for alarm valves
BE392862A (hu) 1931-12-08
US2891855A (en) 1954-08-16 1959-06-23 Geigy Ag J R Compositions and methods for influencing the growth of plants
US3235361A (en) 1962-10-29 1966-02-15 Du Pont Method for the control of undesirable vegetation
US3060084A (en) 1961-06-09 1962-10-23 Du Pont Improved homogeneous, readily dispersed, pesticidal concentrate
US3299566A (en) 1964-06-01 1967-01-24 Olin Mathieson Water soluble film containing agricultural chemicals
US3309192A (en) 1964-12-02 1967-03-14 Du Pont Method of controlling seedling weed grasses
US4144050A (en) 1969-02-05 1979-03-13 Hoechst Aktiengesellschaft Micro granules for pesticides and process for their manufacture
US3852416A (en) 1971-05-27 1974-12-03 L Grubb Tick and flea collar of solid solution plasticized vinylic resin-carbamate insecticide
US3950360A (en) 1972-06-08 1976-04-13 Sankyo Company Limited Antibiotic substances
US3984564A (en) 1972-06-08 1976-10-05 Sankyo Company Limited Antibiotic substances B-41, their production and their use as insecticides and acaricides
US3920442A (en) 1972-09-18 1975-11-18 Du Pont Water-dispersible pesticide aggregates
US3854216A (en) 1973-05-14 1974-12-17 Owatonna Tool Co Disc brake tool
US3879532A (en) 1974-01-18 1975-04-22 Shell Oil Co Control by isoxazoles of endoparasitic nematodes
SE434277B (sv) 1976-04-19 1984-07-16 Merck & Co Inc Sett att framstella nya antihelmintiskt verkande foreningar genom odling av streptomyces avermitilis
US4172714A (en) 1976-12-20 1979-10-30 E. I. Du Pont De Nemours And Company Dry compactible, swellable herbicidal compositions and pellets produced therefrom
US4129568A (en) 1977-05-12 1978-12-12 Monsanto Company 2-[3-Aryl-2-isoxazolin-5-yl]benzoates
US4199569A (en) 1977-10-03 1980-04-22 Merck & Co., Inc. Selective hydrogenation products of C-076 compounds and derivatives thereof
ES488154A0 (es) 1979-02-05 1981-04-16 Schering Corp Un procedimiento para la preparacion de un compuesto d-(treo-1-aril-2-acilamido-3-fluor-1-propanol
US4224901A (en) 1979-04-16 1980-09-30 Carey Jr Sam H Combination inner flea-tick collar and outer protective collar, for animals
GB2095558B (en) 1981-03-30 1984-10-24 Avon Packers Ltd Formulation of agricultural chemicals
US4820695A (en) 1982-09-13 1989-04-11 Eli Lilly And Company C-20-dihydro-deoxy-(cyclic amino)-derivatives of macrolide antibiotics
DE3246493A1 (de) 1982-12-16 1984-06-20 Bayer Ag, 5090 Leverkusen Verfahren zur herstellung von wasserdispergierbaren granulaten
IT1173213B (it) 1984-02-03 1987-06-18 Zambon Spa Procedimento per fluorurare alcuni derivati dall'1l-fenil-2-ammino-1,3-propandiolo e loro intermedi
US5105009A (en) 1983-06-02 1992-04-14 Zambon S.P.A. Intermediates for the preparation of 1-(phenyl)-1-hydroxy-2-amino-3-fluoropropane derivatives
US5332835A (en) 1984-02-03 1994-07-26 Zambon S.P.A. Process for fluorinating 1-phenyl-2-amino-1,3-propanediol compounds and new oxazoline compounds useful in this process
US4973750A (en) 1984-09-19 1990-11-27 Schering Corporation Preparation of (threo)-1-aryl-2-acylamido-3-fluoro-1-propanols
US4582918A (en) 1984-09-19 1986-04-15 Schering Corporation Preparation of intermediates for (threo)-1-aryl-2-acylamido-3-fluoro-1-propanols
ES8800986A1 (es) 1985-07-27 1987-12-01 Pfizer Un procedimiento para la produccion de un nuevo derivado de avermectina
US4916154A (en) 1986-09-12 1990-04-10 American Cyanamid Company 23-Imino derivatives of LL-F28249 compounds
US5180587A (en) 1988-06-28 1993-01-19 E. I. Du Pont De Nemours And Company Tablet formulations of pesticides
US4876352A (en) 1988-09-14 1989-10-24 Schering Corporation Pressurized fluorination of hydroxy alkyl groups
US5227494A (en) 1988-09-14 1993-07-13 Schering Corporation Process for preparing oxazoline compounds
ES2166919T3 (es) 1989-08-30 2002-05-01 Kynoch Agrochemicals Proprieta Preparacion de un dispositivo dosificador.
CA2083185A1 (en) 1990-03-12 1991-09-13 William Lawrence Geigle Water-dispersible or water-soluble pesticide granules from heat-activated binders
IL98599A (en) 1990-06-28 1995-06-29 Merck & Co Inc Stable salts of "4-deoxy-" 4-epi-methylamino abramectin and insecticides containing them
DE69122201T2 (de) 1990-10-11 1997-02-06 Sumitomo Chemical Co Pestizide Zusammensetzung
SK281740B6 (sk) 1990-10-25 2001-07-10 Schering Corporation Spôsob prípravy fluórfenikolu a jeho analógov
US5184573A (en) 1992-02-21 1993-02-09 Stevens Jr John L Animal collar
US5352832A (en) 1992-12-18 1994-10-04 Schering Corporation Asymmetric process for preparing florfenicol, thiamphenicol chloramphenicol and oxazoline intermediates
US5399717A (en) 1993-09-29 1995-03-21 Merck & Co., Inc. Glycosidation route to 4"-epi-methylamino-4"-deoxyavermectin B1
US5849736A (en) 1993-11-24 1998-12-15 The Dupont Merck Pharmaceutical Company Isoxazoline and isoxazole fibrinogen receptor antagonists
GB9505651D0 (en) 1995-03-21 1995-05-10 Agrevo Uk Ltd AgrEvo UK Limited
US5555848A (en) 1995-05-17 1996-09-17 Trujillo; Wendy J. Pet/flea collar
CN1076351C (zh) 1996-04-26 2001-12-19 日本曹达株式会社 被杂环取代的苯的衍生物和除草剂
AU726670B2 (en) 1996-06-06 2000-11-16 Dow Agrosciences Llc Benzyloxy substituted aromatics and their use as fungicides and insecticides
US5958888A (en) 1996-07-02 1999-09-28 Merial, Inc. Water miscible macrolide solutions
US6271255B1 (en) 1996-07-05 2001-08-07 Biotica Technology Limited Erythromycins and process for their preparation
US5663361A (en) 1996-08-19 1997-09-02 Schering Corporation Process for preparing intermediates to florfenicol
HRP980291A2 (en) * 1997-06-16 1999-04-30 Lin-Hua Zhang Crystalline roxifiban
US6339063B1 (en) 1997-09-10 2002-01-15 Merck & Co., Inc. 9a-azalides as veterinary antimicrobial agents
JP2003512290A (ja) 1997-09-10 2003-04-02 メルク エンド カムパニー インコーポレーテッド 家畜抗菌剤としての８ａ−アザライド
AP9801420A0 (en) 1998-01-02 1998-12-31 Pfizer Prod Inc Novel macrolides.
US6239112B1 (en) 1998-07-09 2001-05-29 Merial, Inc. Water miscible macrolide solutions
CZ299375B6 (cs) 1998-11-30 2008-07-09 Nihon Nohyaku Co., Ltd. Ftalamidové deriváty nebo jejich soli, zemedelsko-zahradnický insekticid je obsahující a jeho použití
CA2411293A1 (en) 1999-01-28 2000-07-28 Pfizer Products Inc. Novel azalides and methods of making same
GB2351081A (en) 1999-06-18 2000-12-20 Lilly Forschung Gmbh Pharmaceutically active imidazoline compounds and analogues thereof
EP1250343B1 (en) 2000-01-27 2003-06-25 Pfizer Products Inc. Azalide antibiotic compositions
MY138097A (en) 2000-03-22 2009-04-30 Du Pont Insecticidal anthranilamides
DE10114597A1 (de) 2001-03-23 2002-10-02 Bayer Cropscience Gmbh Arylisoxazolin-Derivate, Verfahren zu ihrer Herstellung und ihre Verwendung als Schädlingsbekämpfungsmittel
MXPA03009786A (es) 2001-04-27 2004-01-29 Pfizer Prod Inc Procedimiento para preparar derivados de 9-desoxo-9a-aza-9a-homoeritromicina a 4"-sustituidos.
TWI325302B (en) 2001-08-13 2010-06-01 Du Pont Benzoxazinone compounds
TW200724033A (en) 2001-09-21 2007-07-01 Du Pont Anthranilamide arthropodicide treatment
WO2003077828A2 (en) 2002-03-08 2003-09-25 Schering-Plough, Ltd. Novel florfenicol-type antibiotics
WO2004018410A1 (ja) 2002-08-26 2004-03-04 Nissan Chemical Industries, Ltd. 置換ベンズアニリド化合物及び有害生物防除剤
PL209772B1 (pl) 2003-01-28 2011-10-31 Du Pont Antraniloamidy, środek do zwalczania szkodnika będącego bezkręgowcem i sposób zwalczania szkodnika będącego bezkręgowcem
DE10320782A1 (de) 2003-05-09 2004-11-25 Bayer Cropscience Ag Substituierte Oxyarene
JP2005272452A (ja) 2004-02-23 2005-10-06 Nissan Chem Ind Ltd 置換ベンズアニリド化合物及び有害生物防除剤
KR101197482B1 (ko) 2004-03-05 2012-11-09 닛산 가가쿠 고교 가부시키 가이샤 이속사졸린 치환 벤즈아미드 화합물 및 유해생물 방제제
WO2005094329A2 (en) 2004-03-26 2005-10-13 Cytokine Pharmasciences, Inc. Compouns, compositions, processes of making, and methods of use related to inhibiting macrophage migration inhibitory factor
JP5051340B2 (ja) 2005-06-06 2012-10-17 日産化学工業株式会社 置換イソキサゾリン化合物及び有害生物防除剤
MY146795A (en) 2005-06-09 2012-09-28 Novartis Ag Process for the synthesis of organic compounds
CA2621228C (en) 2005-09-02 2014-05-27 Nissan Chemical Industries, Ltd. Isoxazoline-substituted benzamide compound and pesticide
JP2007106756A (ja) 2005-09-14 2007-04-26 Nissan Chem Ind Ltd 置換イソキサゾリン化合物及び有害生物防除剤
WO2007070606A2 (en) 2005-12-14 2007-06-21 E. I. Du Pont De Nemours And Company Isoxazolines for controlling invertebrate pests
TW200803740A (en) 2005-12-16 2008-01-16 Du Pont 5-aryl isoxazolines for controlling invertebrate pests
EP1975149B1 (en) 2005-12-26 2012-02-15 Nissan Chemical Industries, Ltd. 1,3-bis(substituted phenyl)-3-hydroxypropan-1-one or 2-propen-1-one compound, and salt thereof
TWI412322B (zh) * 2005-12-30 2013-10-21 Du Pont 控制無脊椎害蟲之異唑啉
WO2007105814A1 (ja) 2006-03-10 2007-09-20 Nissan Chemical Industries, Ltd. 置換イソキサゾリン化合物及び有害生物防除剤
MX2008013307A (es) 2006-04-20 2008-10-27 Du Pont Pirazolinas para controlar plagas de invertebrados.
JPWO2007125984A1 (ja) 2006-04-28 2009-09-10 日本農薬株式会社 イソキサゾリン誘導体及び有害生物防除剤並びにその使用方法
JP2008044880A (ja) 2006-08-15 2008-02-28 Bayer Cropscience Ag 殺虫性イソオキサゾリン類
EP2151437A4 (en) 2007-03-07 2012-05-02 Nissan Chemical Ind Ltd ISOXAZOLINE SUBSTITUTED BENZAMIDE COMPOUND AND PEST CONTROL AGENT
RU2009141185A (ru) 2007-04-10 2011-05-20 Байер КропСайенс АГ (DE) Инсектицидные производные арилизоксазолина
EP2155701B1 (en) 2007-06-13 2013-12-11 E. I. Du Pont de Nemours and Company Isoxazoline insecticides
TWI430995B (zh) 2007-06-26 2014-03-21 Du Pont 萘異唑啉無脊椎有害動物控制劑
PL2957284T3 (pl) 2007-06-27 2018-08-31 E. I. Du Pont De Nemours And Company Sposób zwalczania szkodników zwierzęcych
WO2009001942A1 (ja) 2007-06-27 2008-12-31 Nissan Chemical Industries, Ltd. ３－ヒドロキシプロパン－１－オン化合物、２－プロペン－１－オン化合物およびイソキサゾリン化合物の製造方法
TWI556741B (zh) 2007-08-17 2016-11-11 英特威特國際股份有限公司 異唑啉組成物及其作為抗寄生蟲藥上的應用
TWI649303B (zh) 2007-08-17 2019-02-01 杜邦股份有限公司 製備４-乙醯基-ｎ-〔２-側氧基-２-〔（２，２，２-三氟乙基）胺基〕乙基〕-１-萘甲醯胺之化合物及方法
CN101801940B (zh) 2007-09-10 2013-04-10 日产化学工业株式会社 取代异*唑啉化合物和有害生物防除剂
EP2193124B1 (en) 2007-10-03 2012-12-19 E. I. du Pont de Nemours and Company Naphthalene isoxazoline compounds for control of invertebrate pests
TWI455919B (zh) 2008-04-09 2014-10-11 Du Pont 製備３－三氟甲基查耳酮（ｃｈａｌｃｏｎｅ）之方法
ES2582575T3 (es) * 2008-07-09 2016-09-13 Nissan Chemical Industries, Ltd. Procedimiento para la producción de compuesto de amida del ácido benzoico sustituido con isoxazolina
EP2424347A1 (en) * 2009-04-28 2012-03-07 BASF Corporation Pesticide compositions and applicators

Also Published As

Publication number Publication date
RU2012157267A (ru) 2014-07-10
NZ603584A (en) 2015-02-27
JP2013528177A (ja) 2013-07-08
BR112012030151A2 (pt) 2015-10-20
ZA201208760B (en) 2014-03-26
AU2011258621B2 (en) 2014-08-14
CN102947278B (zh) 2015-08-12
IL223002A0 (en) 2012-12-31
EP2576523B1 (en) 2016-01-13
ES2566402T3 (es) 2016-04-12
HK1183875A1 (zh) 2014-01-10
CL2012003272A1 (es) 2013-08-02
KR20130124458A (ko) 2013-11-14
IL223002A (en) 2016-06-30
AR081226A1 (es) 2012-07-04
HRP20160355T1 (hr) 2016-05-06
EP2576523A1 (en) 2013-04-10
AR117778A2 (es) 2021-08-25
JP5933530B2 (ja) 2016-06-08
RS54677B1 (en) 2016-08-31
UY33397A (es) 2011-12-01
US20130137735A1 (en) 2013-05-30
DK2576523T3 (en) 2016-04-18
GT201200316A (es) 2014-04-08
BR112012030151B1 (pt) 2019-10-08
CN102947278A (zh) 2013-02-27
BR112012030151B8 (pt) 2022-11-08
PL2576523T3 (pl) 2016-08-31
CA2799963A1 (en) 2011-12-01
KR20170015549A (ko) 2017-02-08
AU2011258621A1 (en) 2012-12-06
US8598087B2 (en) 2013-12-03
UA108881C2 (xx) 2015-06-25
SI2576523T1 (sl) 2016-05-31
CA2799963C (en) 2018-01-23
KR102060464B1 (ko) 2019-12-30
MD4363B1 (ro) 2015-08-31
MX2012013758A (es) 2013-01-24
MD4363C1 (ro) 2016-03-31
WO2011149749A1 (en) 2011-12-01
TN2012000557A1 (en) 2014-04-01
MY156670A (en) 2016-03-15
KR20180093114A (ko) 2018-08-20
MD20120125A2 (en) 2013-05-31
MA34247B1 (fr) 2013-05-02

Similar Documents

Publication Publication Date Title
US8598087B2 (en) Crystalline form of 4-[5-[3-chloro-5-(trifluoromethyl)phenyl]-4, 5-dihydro-5-(trifluoromethyl)-3-isoxazolyl]-N-[2-0X0-2-[(2,2,2-trifluoroethyl)amino]ethyl]-1- naph-thalenecarboxamide
DK2158188T3 (en) NAPHTALIN-ISOXAZOLINE AS AN AGENT FOR THE FIGHT AGAINST Invertebrate Pests
US9314025B2 (en) Mixtures of mesoionic pesticides
US20120122680A1 (en) Mesoionic pesticides
CA2684671A1 (en) Isoxazoline insecticides
WO2012087630A1 (en) Pyridine and pyrimidine compounds for controlling invertebrate
RU2575121C2 (ru) Кристаллическая форма 4-[5-[3-хлор-5-(трифторметил)фенил]-4,5-дигидро-5-(трифторметил)-3-изоксазолил]-n-[2-оксо-2-[(2,2,2-трифторэтил)амино]этил]-1-нафталинкарбоксамида
AU2015201191B2 (en) Mesoionic pesticides
AU2018202270A1 (en) Naphthalene isoxazoline invertebrate pest control agents
AU2014262192A1 (en) Crystalline form of 4-[5-[3-chloro-5-(trifluoromethyl)phenyl]-4,5-dihydro-5-(trifluoromethyl)-3-isoxazolyl]-n-[2-oxo-2-[(2,2,2-trifluoroethyl)amino]ethyl]-1-naphthalenecarboxamide