IL223002A - Crystalline form of 4-[5-[3-chloro-5 -(trifluoromethyl) phenyl]-4, 5- dihydro - 5 -(trifluoromethyl)-3-isoxazolyl]-n-[2-oxo-2- [(2, 2, 2-trifluoroethyl)amino] ethyl]-1- naphthalenecarboxamide - Google Patents

Crystalline form of 4-[5-[3-chloro-5 -(trifluoromethyl) phenyl]-4, 5- dihydro - 5 -(trifluoromethyl)-3-isoxazolyl]-n-[2-oxo-2- [(2, 2, 2-trifluoroethyl)amino] ethyl]-1- naphthalenecarboxamide

Info

Publication number
IL223002A
IL223002A IL223002A IL22300212A IL223002A IL 223002 A IL223002 A IL 223002A IL 223002 A IL223002 A IL 223002A IL 22300212 A IL22300212 A IL 22300212A IL 223002 A IL223002 A IL 223002A
Authority
IL
Israel
Prior art keywords
trifluoromethyl
naphthalenecarboxamide
trifluoroethyl
isoxazolyl
dihydro
Prior art date
Application number
IL223002A
Other languages
Hebrew (he)
Other versions
IL223002A0 (en
Original Assignee
Du Pont
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Du Pont filed Critical Du Pont
Publication of IL223002A0 publication Critical patent/IL223002A0/en
Publication of IL223002A publication Critical patent/IL223002A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D261/00—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings
    • C07D261/02—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings
    • C07D261/04—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N25/00—Biocides, pest repellants or attractants, or plant growth regulators, characterised by their forms, or by their non-active ingredients or by their methods of application, e.g. seed treatment or sequential application; Substances for reducing the noxious effect of the active ingredients to organisms other than pests
    • A01N25/12—Powders or granules
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
    • A01N43/72—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with nitrogen atoms and oxygen or sulfur atoms as ring hetero atoms
    • A01N43/80—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with nitrogen atoms and oxygen or sulfur atoms as ring hetero atoms five-membered rings with one nitrogen atom and either one oxygen atom or one sulfur atom in positions 1,2
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/42—Oxazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/10—Anthelmintics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/14—Ectoparasiticides, e.g. scabicides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00—Indexing scheme relating to specific properties of organic compounds
    • C07B2200/13—Crystalline forms, e.g. polymorphs

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Zoology (AREA)
  • Environmental Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Engineering & Computer Science (AREA)
  • Dentistry (AREA)
  • Agronomy & Crop Science (AREA)
  • Pest Control & Pesticides (AREA)
  • Plant Pathology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Epidemiology (AREA)
  • Toxicology (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
IL223002A 2010-05-27 2012-11-12 Crystalline form of 4-[5-[3-chloro-5 -(trifluoromethyl) phenyl]-4, 5- dihydro - 5 -(trifluoromethyl)-3-isoxazolyl]-n-[2-oxo-2- [(2, 2, 2-trifluoroethyl)amino] ethyl]-1- naphthalenecarboxamide IL223002A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US34895810P 2010-05-27 2010-05-27
PCT/US2011/037083 WO2011149749A1 (en) 2010-05-27 2011-05-19 Crystalline form of 4- [5 - [3 -chloro-5 - (trifluoromethyl) phenyl] -4, 5 - dihydro - 5 - (trifluoromethyl) -3 - isoxazolyl] -n- [2-0x0-2- [ ( 2, 2, 2 - trifluoroethyl) amino] ethyl] -1- naphthalenecarboxamide

Publications (2)

Publication Number Publication Date
IL223002A0 IL223002A0 (en) 2012-12-31
IL223002A true IL223002A (en) 2016-06-30

Family

ID=44359642

Family Applications (1)

Application Number Title Priority Date Filing Date
IL223002A IL223002A (en) 2010-05-27 2012-11-12 Crystalline form of 4-[5-[3-chloro-5 -(trifluoromethyl) phenyl]-4, 5- dihydro - 5 -(trifluoromethyl)-3-isoxazolyl]-n-[2-oxo-2- [(2, 2, 2-trifluoroethyl)amino] ethyl]-1- naphthalenecarboxamide

Country Status (30)

Country Link
US (1) US8598087B2 (en)
EP (1) EP2576523B1 (en)
JP (1) JP5933530B2 (en)
KR (3) KR102060464B1 (en)
CN (1) CN102947278B (en)
AR (2) AR081226A1 (en)
AU (1) AU2011258621B2 (en)
BR (1) BR112012030151B8 (en)
CA (1) CA2799963C (en)
CL (1) CL2012003272A1 (en)
DK (1) DK2576523T3 (en)
ES (1) ES2566402T3 (en)
GT (1) GT201200316A (en)
HK (1) HK1183875A1 (en)
HR (1) HRP20160355T1 (en)
HU (1) HUE028501T2 (en)
IL (1) IL223002A (en)
MA (1) MA34247B1 (en)
MD (1) MD4363C1 (en)
MX (1) MX2012013758A (en)
MY (1) MY156670A (en)
NZ (1) NZ603584A (en)
PL (1) PL2576523T3 (en)
RS (1) RS54677B1 (en)
SI (1) SI2576523T1 (en)
TN (1) TN2012000557A1 (en)
UA (1) UA108881C2 (en)
UY (1) UY33397A (en)
WO (1) WO2011149749A1 (en)
ZA (1) ZA201208760B (en)

Families Citing this family (42)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TWI487486B (en) 2009-12-01 2015-06-11 Syngenta Participations Ag Insecticidal compounds based on isoxazoline derivatives
DK2755473T3 (en) 2011-09-12 2019-03-11 Merial Inc PARACITICIDE COMPOSITIONS CONTAINING AN ISOXAZOLINE ACTIVE SUBSTANCE, PROCEDURES AND APPLICATIONS THEREOF
DE112013000869T5 (en) * 2012-02-06 2014-10-16 Merial Ltd. Oral parasiticidal veterinary compositions comprising systemic agents, methods and uses thereof
RU2765231C2 (en) 2012-04-04 2022-01-26 Интервет Интернэшнл Б.В. Soft chewable pharmaceutical products
CN104768377A (en) 2012-10-01 2015-07-08 巴斯夫欧洲公司 Pesticidally active mixtures comprising anthranilamide compounds
WO2014053401A2 (en) 2012-10-01 2014-04-10 Basf Se Method of improving plant health
US20150250175A1 (en) 2012-10-01 2015-09-10 Basf Se Pesticidally active mixtures comprising anthranilamide compounds
WO2014053407A1 (en) 2012-10-01 2014-04-10 Basf Se N-thio-anthranilamide compounds and their use as pesticides
WO2014053403A1 (en) 2012-10-01 2014-04-10 Basf Se Method of controlling insecticide resistant insects
US20150250174A1 (en) 2012-10-01 2015-09-10 Basf Se Use of n-thio-anthranilamide compounds on cultivated plants
WO2014053406A1 (en) 2012-10-01 2014-04-10 Basf Se Method of controlling ryanodine-modulator insecticide resistant insects
US9532946B2 (en) 2012-11-20 2017-01-03 Intervet Inc. Manufacturing of semi-plastic pharmaceutical dosage units
WO2014079820A1 (en) 2012-11-22 2014-05-30 Basf Se Use of anthranilamide compounds for reducing insect-vectored viral infections
AU2013357564A1 (en) 2012-12-14 2015-07-02 Basf Se Malononitrile compounds for controlling animal pests
CN105189489A (en) 2012-12-27 2015-12-23 巴斯夫欧洲公司 2-(pyridin-3-yl)-5-hetaryl-thiazole compounds carrying an imine or imine-derived substituent for combating invertebrate pests
SI2953942T1 (en) 2013-02-06 2018-03-30 Bayer Cropscience Ag Halogen-substituted pyrazole derivatives as pesticides
WO2014126208A1 (en) * 2013-02-14 2014-08-21 日産化学工業株式会社 Crystalline polymorph of isoxazoline-substituted benzamide compound, and method for producing same
CN105451771B (en) 2013-03-15 2020-05-19 阿根塔创新有限公司 Chewable formulation
EP2986598B1 (en) 2013-04-19 2017-03-29 Basf Se N-substituted acyl-imino-pyridine compounds and derivatives for combating animal pests
WO2014202751A1 (en) 2013-06-21 2014-12-24 Basf Se Methods for controlling pests in soybean
AR097138A1 (en) 2013-07-15 2016-02-24 Basf Se PESTICIDED COMPOUNDS
AU2014323072B2 (en) 2013-09-19 2018-01-18 Basf Se N-acylimino heterocyclic compounds
WO2015055497A1 (en) 2013-10-16 2015-04-23 Basf Se Substituted pesticidal pyrazole compounds
EA201600326A1 (en) 2013-10-18 2016-10-31 Басф Агрокемикэл Продактс Б.В. APPLICATION OF PESTICIDAL ACTIVE DERIVATIVE CARBOXAMIDE IN METHODS OF APPLICATION AND TREATMENT OF SEEDS AND SOIL
WO2015091645A1 (en) 2013-12-18 2015-06-25 Basf Se Azole compounds carrying an imine-derived substituent
BR112016014171A2 (en) 2013-12-18 2017-08-08 Basf Se COMPOST, AGRICULTURAL COMPOSITION, USE OF A COMPOUND, METHODS FOR COMBATING OR CONTROLING PESTS, FOR PROTECTING VEGETABLES AND FOR PROTECTING MATERIAL FOR THE PROPAGATION OF VEGETABLES AND TREATMENT METHOD
ES2683693T3 (en) 2014-01-03 2018-09-27 Bayer Animal Health Gmbh New pyrazolyl heteroarylamides as pesticide agents
WO2015104422A1 (en) 2014-01-13 2015-07-16 Basf Se Dihydrothiophene compounds for controlling invertebrate pests
AU2015289246B2 (en) 2014-07-15 2019-07-25 Elanco Animal Health Gmbh Aryl-triazolyl pyridines as pest control agents
UY36570A (en) * 2015-02-26 2016-10-31 Merial Inc INJECTABLE FORMULATIONS OF PROLONGED ACTION THAT INCLUDE AN ISOXAZOLINE ACTIVE AGENT, METHODS AND USES OF THE SAME
KR102593069B1 (en) * 2015-04-08 2023-10-23 뵈링거 잉겔하임 애니멀 헬스 유에스에이 인코포레이티드 Extended release injectable formulations comprising an isoxazoline active agent, methods and uses thereof
UY37137A (en) 2016-02-24 2017-09-29 Merial Inc ANTIPARASITARY COMPOUNDS OF ISOXAZOLINE, INJECTABLE FORMULATIONS OF PROLONGED ACTION THAT INCLUDE THEM, METHODS AND USES OF THE SAME
WO2018039508A1 (en) 2016-08-25 2018-03-01 Merial, Inc. Method for reducing unwanted effects in parasiticidal treatments
WO2018071535A1 (en) 2016-10-14 2018-04-19 Merial, Inc. Pesticidal and parasiticidal vinyl isoxazoline compounds
JP7222909B2 (en) 2017-04-05 2023-02-15 ベーリンガー・インゲルハイム・アニマル・ヘルス・ユーエスエー・インコーポレイテッド Crystal Forms of (S)-Afoxolaner
KR101988442B1 (en) * 2017-06-30 2019-06-12 주식회사 삼양사 Crystalline functional sweetener
US11589586B2 (en) 2017-08-14 2023-02-28 Boehringer Ingelheim Animal Health USA Inc. Pesticidal and parasiticidal pyrazole-isoxazoline compounds
PE20210170A1 (en) * 2017-11-07 2021-01-29 Intervet Int Bv PROCESS FOR PREPARING BIG SIZE ISOXAZOLINE PARTICLES
PE20201150A1 (en) * 2017-11-07 2020-10-26 Intervet Int Bv INJECTABLE PHARMACEUTICAL COMPOSITIONS OF ISOXAZOLINE AND USES OF THE SAME
WO2021242481A1 (en) 2020-05-28 2021-12-02 Boehringer Ingelheim Animal Health USA Inc. Bi-modal release intra-ruminal capsule device and methods of use thereof
WO2021254445A1 (en) * 2020-06-19 2021-12-23 东莞市东阳光仿制药研发有限公司 Crystal form of gaba inhibitor and preparation method therefor
EP4262789A1 (en) * 2020-12-21 2023-10-25 Boehringer Ingelheim Vetmedica GmbH Parasiticidal collar comprising isoxazoline compounds

Family Cites Families (96)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US1815604A (en) 1922-10-31 1931-07-21 Winthrop Chem Co Organic mercury compound
US1679404A (en) 1926-02-04 1928-08-07 Rockwood Sprinkler Co Massachusetts Constant-alarm device for alarm valves
BE403499A (en) 1931-12-08
US2891855A (en) 1954-08-16 1959-06-23 Geigy Ag J R Compositions and methods for influencing the growth of plants
US3235361A (en) 1962-10-29 1966-02-15 Du Pont Method for the control of undesirable vegetation
US3060084A (en) 1961-06-09 1962-10-23 Du Pont Improved homogeneous, readily dispersed, pesticidal concentrate
US3299566A (en) 1964-06-01 1967-01-24 Olin Mathieson Water soluble film containing agricultural chemicals
US3309192A (en) 1964-12-02 1967-03-14 Du Pont Method of controlling seedling weed grasses
US4144050A (en) 1969-02-05 1979-03-13 Hoechst Aktiengesellschaft Micro granules for pesticides and process for their manufacture
US3852416A (en) 1971-05-27 1974-12-03 L Grubb Tick and flea collar of solid solution plasticized vinylic resin-carbamate insecticide
US3984564A (en) 1972-06-08 1976-10-05 Sankyo Company Limited Antibiotic substances B-41, their production and their use as insecticides and acaricides
US3950360A (en) 1972-06-08 1976-04-13 Sankyo Company Limited Antibiotic substances
US3920442A (en) 1972-09-18 1975-11-18 Du Pont Water-dispersible pesticide aggregates
US3854216A (en) 1973-05-14 1974-12-17 Owatonna Tool Co Disc brake tool
US3879532A (en) 1974-01-18 1975-04-22 Shell Oil Co Control by isoxazoles of endoparasitic nematodes
SE434277B (en) 1976-04-19 1984-07-16 Merck & Co Inc SET TO MAKE NEW ANTIHELMINTICALLY EFFECTIVE ASSOCIATIONS BY CULTIVATING STREPTOMYCS AVERMITILIS
US4172714A (en) 1976-12-20 1979-10-30 E. I. Du Pont De Nemours And Company Dry compactible, swellable herbicidal compositions and pellets produced therefrom
US4129568A (en) 1977-05-12 1978-12-12 Monsanto Company 2-[3-Aryl-2-isoxazolin-5-yl]benzoates
US4199569A (en) 1977-10-03 1980-04-22 Merck & Co., Inc. Selective hydrogenation products of C-076 compounds and derivatives thereof
ES8104203A1 (en) 1979-02-05 1981-04-16 Schering Corp 1-Aryl-2-acylamido-3-fluoro-1-propanol acylates, methods for their manufacture and intermediates useful therein, methods for their use as antibacterial agents and compositions useful therefor
US4224901A (en) 1979-04-16 1980-09-30 Carey Jr Sam H Combination inner flea-tick collar and outer protective collar, for animals
GB2095558B (en) 1981-03-30 1984-10-24 Avon Packers Ltd Formulation of agricultural chemicals
US4820695A (en) 1982-09-13 1989-04-11 Eli Lilly And Company C-20-dihydro-deoxy-(cyclic amino)-derivatives of macrolide antibiotics
DE3246493A1 (en) 1982-12-16 1984-06-20 Bayer Ag, 5090 Leverkusen METHOD FOR PRODUCING WATER-DISPERSIBLE GRANULES
US5105009A (en) 1983-06-02 1992-04-14 Zambon S.P.A. Intermediates for the preparation of 1-(phenyl)-1-hydroxy-2-amino-3-fluoropropane derivatives
IT1173213B (en) 1984-02-03 1987-06-18 Zambon Spa PROCEDURE TO FLUORINE SOME DERIVATIVES FROM 1L-FENYL-2-AMINO-1,3-PROPANDIOL AND THEIR INTERMEDIATES
US5332835A (en) 1984-02-03 1994-07-26 Zambon S.P.A. Process for fluorinating 1-phenyl-2-amino-1,3-propanediol compounds and new oxazoline compounds useful in this process
US4973750A (en) 1984-09-19 1990-11-27 Schering Corporation Preparation of (threo)-1-aryl-2-acylamido-3-fluoro-1-propanols
US4582918A (en) 1984-09-19 1986-04-15 Schering Corporation Preparation of intermediates for (threo)-1-aryl-2-acylamido-3-fluoro-1-propanols
ES8800986A1 (en) 1985-07-27 1987-12-01 Pfizer Antiparasitic avermectin and milbemycin derivatives and process for their preparation.
US4916154A (en) 1986-09-12 1990-04-10 American Cyanamid Company 23-Imino derivatives of LL-F28249 compounds
US5180587A (en) 1988-06-28 1993-01-19 E. I. Du Pont De Nemours And Company Tablet formulations of pesticides
US4876352A (en) 1988-09-14 1989-10-24 Schering Corporation Pressurized fluorination of hydroxy alkyl groups
US5227494A (en) 1988-09-14 1993-07-13 Schering Corporation Process for preparing oxazoline compounds
EP0777964B1 (en) 1989-08-30 2001-11-14 Kynoch Agrochemicals (Proprietary) Limited Preparation of a dosage device
ES2065680T3 (en) 1990-03-12 1995-02-16 Du Pont PESTICIDE GRANULES DISPERSIBLE IN WATER OR SOLUBLE IN WATER FROM HEAT ACTIVATED BINDERS.
IL98599A (en) 1990-06-28 1995-06-29 Merck & Co Inc Stable salts of 4"-deoxy-4"-epi-methylamino avermectin b1a/b1b and insecticidal compositions containing them
DE69122201T2 (en) 1990-10-11 1997-02-06 Sumitomo Chemical Co Pesticides composition
SK281740B6 (en) 1990-10-25 2001-07-10 Schering Corporation Process for preparing florfenicol, its analogs and oxazoline intermediates thereto
US5184573A (en) 1992-02-21 1993-02-09 Stevens Jr John L Animal collar
US5352832A (en) 1992-12-18 1994-10-04 Schering Corporation Asymmetric process for preparing florfenicol, thiamphenicol chloramphenicol and oxazoline intermediates
US5399717A (en) 1993-09-29 1995-03-21 Merck & Co., Inc. Glycosidation route to 4"-epi-methylamino-4"-deoxyavermectin B1
US5849736A (en) 1993-11-24 1998-12-15 The Dupont Merck Pharmaceutical Company Isoxazoline and isoxazole fibrinogen receptor antagonists
GB9505651D0 (en) 1995-03-21 1995-05-10 Agrevo Uk Ltd AgrEvo UK Limited
US5555848A (en) 1995-05-17 1996-09-17 Trujillo; Wendy J. Pet/flea collar
BR9708828A (en) 1996-04-26 1999-08-03 Nippon Soda Co Herbicidal compound and composition
AU726670B2 (en) 1996-06-06 2000-11-16 Dow Agrosciences Llc Benzyloxy substituted aromatics and their use as fungicides and insecticides
US5958888A (en) 1996-07-02 1999-09-28 Merial, Inc. Water miscible macrolide solutions
US6271255B1 (en) 1996-07-05 2001-08-07 Biotica Technology Limited Erythromycins and process for their preparation
US5663361A (en) 1996-08-19 1997-09-02 Schering Corporation Process for preparing intermediates to florfenicol
HRP980291A2 (en) * 1997-06-16 1999-04-30 Lin-Hua Zhang Crystalline roxifiban
US6339063B1 (en) 1997-09-10 2002-01-15 Merck & Co., Inc. 9a-azalides as veterinary antimicrobial agents
JP2003512290A (en) 1997-09-10 2003-04-02 メルク エンド カムパニー インコーポレーテッド 8a-azalide as a livestock antibacterial agent
AP9801420A0 (en) 1998-01-02 1998-12-31 Pfizer Prod Inc Novel macrolides.
US6239112B1 (en) 1998-07-09 2001-05-29 Merial, Inc. Water miscible macrolide solutions
CZ299375B6 (en) 1998-11-30 2008-07-09 Nihon Nohyaku Co., Ltd. Phthalimide derivatives or salts thereof, agricultural- horticultural insecticidal agent and application method thereof
CA2411293A1 (en) 1999-01-28 2000-07-28 Pfizer Products Inc. Novel azalides and methods of making same
GB2351081A (en) 1999-06-18 2000-12-20 Lilly Forschung Gmbh Pharmaceutically active imidazoline compounds and analogues thereof
CA2398485C (en) 2000-01-27 2008-01-29 Pfizer Products Inc. Azalide antibiotic compositions
MY138097A (en) 2000-03-22 2009-04-30 Du Pont Insecticidal anthranilamides
DE10114597A1 (en) 2001-03-23 2002-10-02 Bayer Cropscience Gmbh Arylisoxazoline derivatives, process for their preparation and their use as pesticides
WO2002088158A1 (en) 2001-04-27 2002-11-07 Pfizer Products Inc. Process for preparing 4'-substituted-9-deoxo-9a-aza-9a-homoerythromycin a derivatives
TWI312274B (en) 2001-08-13 2009-07-21 Du Pont Method for controlling particular insect pests by applying anthranilamide compounds
TW200724033A (en) 2001-09-21 2007-07-01 Du Pont Anthranilamide arthropodicide treatment
EP1487785A2 (en) 2002-03-08 2004-12-22 Schering-Plough Ltd. Novel florfenicol-type antibiotics
WO2004018410A1 (en) 2002-08-26 2004-03-04 Nissan Chemical Industries, Ltd. Substituted benzanilide compound and pest control agent
EP2264022B1 (en) 2003-01-28 2013-07-24 E. I. du Pont de Nemours and Company Cyano anthranilamide insecticides
DE10320782A1 (en) 2003-05-09 2004-11-25 Bayer Cropscience Ag Substituted oxyarenes
JP2005272452A (en) 2004-02-23 2005-10-06 Nissan Chem Ind Ltd Substituted benzanilide compound and pesticide
ES2526614T3 (en) 2004-03-05 2015-01-13 Nissan Chemical Industries, Ltd. Isoxazoline-substituted benzamide compound and harmful organisms control agent
AU2005228417A1 (en) 2004-03-26 2005-10-13 Cytokine Pharmasciences, Inc. Compouns, compositions, processes of making, and methods of use related to inhibiting macrophage migration inhibitory factor
JP5051340B2 (en) 2005-06-06 2012-10-17 日産化学工業株式会社 Substituted isoxazoline compounds and pest control agents
MY146795A (en) 2005-06-09 2012-09-28 Novartis Ag Process for the synthesis of organic compounds
AU2006285613B2 (en) 2005-09-02 2011-11-17 Nissan Chemical Corporation Isoxazoline-substituted benzamide compound and harmful organism-controlling agent
JP2007106756A (en) 2005-09-14 2007-04-26 Nissan Chem Ind Ltd Substituted isoxazoline compound and pesticide
BRPI0620668A2 (en) 2005-12-14 2011-11-22 Du Pont compound of formula 1, composition comprising compound, invertebrate pest control composition, spray composition, bait composition, trap device, invertebrate pest control methods, cockroach, ants or termites control method and protection method. seeds against invertebrate pests
TW200803740A (en) 2005-12-16 2008-01-16 Du Pont 5-aryl isoxazolines for controlling invertebrate pests
JP5304981B2 (en) 2005-12-26 2013-10-02 日産化学工業株式会社 1,3-bis (substituted phenyl) -3-hydroxypropan-1-one and 2-propen-1-one compounds and salts thereof
TWI412322B (en) * 2005-12-30 2013-10-21 Du Pont Isoxazolines for controlling invertebrate pests
EP1997813B1 (en) 2006-03-10 2010-05-05 Nissan Chemical Industries, Ltd. Substituted isoxazoline compound and pest control agent
BRPI0710403A2 (en) 2006-04-20 2011-08-09 Du Pont compound composition, control composition, spraying, bait, trap device, control methods, protection methods, treated seed, protective composition
JPWO2007125984A1 (en) 2006-04-28 2009-09-10 日本農薬株式会社 Isoxazoline derivatives, pest control agents and methods of use
JP2008044880A (en) 2006-08-15 2008-02-28 Bayer Cropscience Ag Insecticidal isooxazolines
JP5206993B2 (en) 2007-03-07 2013-06-12 日産化学工業株式会社 Isoxazoline-substituted benzamide compounds and pest control agents
KR20090130064A (en) 2007-04-10 2009-12-17 바이엘 크롭사이언스 아게 Insecticidal aryl isoxazoline derivatives
ES2445651T3 (en) * 2007-06-13 2014-03-04 E. I. Du Pont De Nemours And Company Isoxazoline insecticides
TWI430995B (en) 2007-06-26 2014-03-21 Du Pont Naphthalene isoxazoline invertebrate pest control agents
ES2666187T3 (en) 2007-06-27 2018-05-03 E. I. Du Pont De Nemours And Company Pest control procedure in animals
WO2009001942A1 (en) 2007-06-27 2008-12-31 Nissan Chemical Industries, Ltd. Method for production of 3-hydroxypropan-1-one compound, method for production of 2-propen-1-one compound, and method for production of isoxazoline compound
TWI556741B (en) 2007-08-17 2016-11-11 英特威特國際股份有限公司 Isoxazoline compositions and their use as antiparasitics
TWI461411B (en) 2007-08-17 2014-11-21 Du Pont Method for preparing 5-haloalkyl-4,5-dihydroisoxazole derivatives
CN101801940B (en) 2007-09-10 2013-04-10 日产化学工业株式会社 Substituted isoxazoline compound and pest control agent
JP5676262B2 (en) 2007-10-03 2015-02-25 イー・アイ・デュポン・ドウ・ヌムール・アンド・カンパニーＥ．Ｉ．Ｄｕ Ｐｏｎｔ Ｄｅ Ｎｅｍｏｕｒｓ Ａｎｄ Ｃｏｍｐａｎｙ Naphthalene isoxazoline compounds for the control of harmful invertebrates
TW201444787A (en) * 2008-04-09 2014-12-01 Du Pont Method for preparing 3-trifluoromethyl chalcones
ES2582575T3 (en) * 2008-07-09 2016-09-13 Nissan Chemical Industries, Ltd. Process for the production of isoxazoline-substituted benzoic acid amide compound
JP5675776B2 (en) * 2009-04-28 2015-02-25 ビーエーエスエフ コーポレーション Pesticide composition and spreader

Also Published As

Publication number Publication date
TN2012000557A1 (en) 2014-04-01
MD4363C1 (en) 2016-03-31
BR112012030151A2 (en) 2015-10-20
KR20130124458A (en) 2013-11-14
SI2576523T1 (en) 2016-05-31
GT201200316A (en) 2014-04-08
RU2012157267A (en) 2014-07-10
AU2011258621B2 (en) 2014-08-14
AR081226A1 (en) 2012-07-04
NZ603584A (en) 2015-02-27
MX2012013758A (en) 2013-01-24
JP5933530B2 (en) 2016-06-08
DK2576523T3 (en) 2016-04-18
CN102947278A (en) 2013-02-27
KR20180093114A (en) 2018-08-20
MD20120125A2 (en) 2013-05-31
RS54677B1 (en) 2016-08-31
WO2011149749A1 (en) 2011-12-01
JP2013528177A (en) 2013-07-08
AR117778A2 (en) 2021-08-25
CL2012003272A1 (en) 2013-08-02
PL2576523T3 (en) 2016-08-31
BR112012030151B8 (en) 2022-11-08
ES2566402T3 (en) 2016-04-12
KR102060464B1 (en) 2019-12-30
US8598087B2 (en) 2013-12-03
UA108881C2 (en) 2015-06-25
UY33397A (en) 2011-12-01
AU2011258621A1 (en) 2012-12-06
CA2799963C (en) 2018-01-23
EP2576523A1 (en) 2013-04-10
MY156670A (en) 2016-03-15
US20130137735A1 (en) 2013-05-30
HUE028501T2 (en) 2016-12-28
CN102947278B (en) 2015-08-12
KR20170015549A (en) 2017-02-08
HK1183875A1 (en) 2014-01-10
IL223002A0 (en) 2012-12-31
BR112012030151B1 (en) 2019-10-08
MA34247B1 (en) 2013-05-02
ZA201208760B (en) 2014-03-26
HRP20160355T1 (en) 2016-05-06
EP2576523B1 (en) 2016-01-13
MD4363B1 (en) 2015-08-31
CA2799963A1 (en) 2011-12-01

Similar Documents

Publication Publication Date Title
HK1183875A1 (en) Crystalline form of 4- [5 - [3 -chloro-5 - (trifluoromethyl) phenyl]-4, 5 - dihydro - 5 - (trifluoromethyl) -3 - isoxazolyl]-n- [2-oxo-2- [ ( 2, 2, 2 - trifluoroethyl) amino]ethyl]-1- naphthalenecarboxamide 4-[5-[3--5-()]-45--5-()-3-]-n-[2-- 2-[(222-)]]-1-
IL195882A (en) Crystalline forms of (1s)-1,5-anhydro-1-c-(3-(phenyl)methyl)phenyl)-d-glucitol derivatives with amino acids and use thereof for the treatment of diabetes
IL242279A0 (en) Substituted 3-chloro-n-[3-(pyrimidin-2-ylamino)phenyl]propanamide compounds, and salts thereof
PL2559689T3 (en) Preparation process for crystalline forms of 3-[5-(2-fluorophenyl)-[1,2,4]oxadiazol-3-yl]benzoic acid
IL207854A0 (en) Crystal forms of 5-[3-(2,5-dichloro-4, 6-dimethyl-1-oxy-pyridine-3-yl)[1,2,4]oxadiazol-5-yl]-3-nit robenzene-1,2-diol
LT2890699T (en) Crystalline forms of 1-(5`-(5-(3,5-dichloro-4-fluorophenyl)-5-(trifluoromethyl)-4,5-dihydroisoxazol-3-yl)-3`h-spiro[azetidine-3,1`-isobenzofuran]-1-yl)-2-(methylsulfonyl)ethanone
WO2013186792A3 (en) Process for preparation of azilsartan medoxomil and its salts
EP2327697A4 (en) The salts of n-ý4-(1-cyanocyclopentyl)phenyl¨-2-(4-pyridyl methyl)amino-3-pyridinecarboxamide
EP2613787A4 (en) Processes for the preparation of 4-{4-[5(s)-(aminomethyl)-2-oxo-1,3-oxazolidin-3-yl]phenyl} morpholin-3-one
EP2297140A4 (en) Novel 1,2,4 oxadiazole compounds and methods of use thereof
PL384446A1 (en) Salt of 5-[[4-[2-(methyl-2-pyridinamino)ethoxy]phenyl]methyl]-2,4-tiazolidynodion with malonic acid and its production method
IL216655A0 (en) Trans-4-[[(5s)-5-[[[3,5-bis(trifluoromethyl)phenyl]methyl] (2-methyl-2h-tetrazol-5-yl)amino]-2,3,4,5-tetahydro-7,9-dimethyl-1h-1-benzazepin-1-yl]methyl]-cyclohexanecarboxylic acid
HK1151794A1 (en) Process for the preparation of 5-(2-amino-pyrimidin-4-yl)-2-aryl-1h- pyrrole-3-carboxamides 5-(2---4-)-2--1h--3-
HK1189591A1 (en) Hydrochloride salt of 5-r3-f3-tivdroxyphenoxy)azetidi-1-v-5-methyl-2 2- diphenylhexanamide 5-[3-(3-)-1-]-5--22-
ZA201103405B (en) Oxadiazole fused heterocyclic derivatives useful for the treatment of multiple sclerosis
IL267557B (en) Process for preparing 5-[[4-[2-[5-(1-hydroxyethyl)-2-pyridinyl]ethoxy]phenyl]methyl]-2,4-thiazolidinedione and salts thereof
ZA201402756B (en) Immediate release 4-methyl-3-[[4-(3-pyridinyl)]amino]-n-[5-(4-methyl- 1h-imidazol-1-yl)-3-(trifluoromethyl)phenyl]benzamide formulation
HK1175781A1 (en) Process for the preparation of 5-(2-amino-pyrimidin-4-yl)-2-aryl-1h- pyrrole-3-carbox-amides 5-(2---4-)-2--1h--3-
EP2451803A4 (en) Method for preparing 5-chloro-n-({(5s)-2-oxo-3-[4-(5,6-dihydro-4h-[1,2,4]triazin-1-yl)phenyl]-1,3-oxazolidin-5-yl}methyl)thiophen-2-carboxamide derivative and intermediate used therein
TH134721B (en) Crystalline form of 4- [5- [3- chloro-5- (trifluoromethyl) phenyl] -4,5- dihydro -5- (trifluoromethyl). -3-isoxazolil] -N- [2-oxo-2 - [(2,2,2, -trifluoroethyl) amino] ethyl] -1- Naphthalene Carboxamide
PL392676A1 (en) Photochromic copolymers of 4-[(E)-[4-[(3.4-dimethylisoxazole-5-yl) sulphamoyl]phenyl]azo]phenyl methacrylate and process for the preparation thereof
PL392677A1 (en) Photochromic copolymers of 4-[(E)-[4-[(3.4-dimethylisoxazole-5-yl) sulphamoyl]phenyl]azo]phenyl methacrylate and process for the preparation thereof
IL209154A0 (en) Process for controlling the particle size of a 3-(trifluoromethyl)phenyl]-1-aminopropane derivative
PL392673A1 (en) Copolymers of photochromic 4-[(E)-[4-[(5-methylisoxazole-3-yl) sulphamoyl]phenyl]azo]phenyl methacrylate and process for the preparation thereof
PL392674A1 (en) Photochromic copolymers of 4-[(E)-[4-[(5-methylisoxazole-3-yl) sulphamoyl]phenyl]azo]phenyl methacrylate and process for the preparation thereof

Legal Events

Date Code Title Description
FF Patent granted
KB Patent renewed
KB Patent renewed
KB Patent renewed