HU906341D0 - Process for producing peptonic derivatives modified with sugar and pharmaceutical preparatives containing these compounds as active substance - Google Patents

Process for producing peptonic derivatives modified with sugar and pharmaceutical preparatives containing these compounds as active substance

Info

Publication number
HU906341D0
HU906341D0 HU906341A HU634187A HU906341D0 HU 906341 D0 HU906341 D0 HU 906341D0 HU 906341 A HU906341 A HU 906341A HU 634187 A HU634187 A HU 634187A HU 906341 D0 HU906341 D0 HU 906341D0
Authority
HU
Hungary
Prior art keywords
peptonic
sugar
compounds
producing
active substance
Prior art date
Application number
HU906341A
Other languages
English (en)
Hungarian (hu)
Inventor
Rainer Albert
Wilfried Bauer
Francois Cardinaux
Monika Mergler
Janos Pless
Walter Prikoszovich
Original Assignee
Sandoz Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sandoz Ag filed Critical Sandoz Ag
Publication of HU906341D0 publication Critical patent/HU906341D0/hu

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/04—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length on carriers
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K9/00—Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D319/00—Heterocyclic compounds containing six-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D319/04—1,3-Dioxanes; Hydrogenated 1,3-dioxanes
    • C07D319/06—1,3-Dioxanes; Hydrogenated 1,3-dioxanes not condensed with other rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/107—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides
    • C07K1/1072—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides by covalent attachment of residues or functional groups
    • C07K1/1077—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides by covalent attachment of residues or functional groups by covalent attachment of residues other than amino acids or peptide residues, e.g. sugars, polyols, fatty acids
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Analytical Chemistry (AREA)
  • Diabetes (AREA)
  • Endocrinology (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Emergency Medicine (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
HU906341A 1986-10-13 1987-10-01 Process for producing peptonic derivatives modified with sugar and pharmaceutical preparatives containing these compounds as active substance HU906341D0 (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
DE3634825 1986-10-13
DE3634797 1986-10-13
DE3634826 1986-10-13
DE3712626 1987-04-14
CH315387 1987-08-17

Publications (1)

Publication Number Publication Date
HU906341D0 true HU906341D0 (en) 1991-04-29

Family

ID=27509117

Family Applications (3)

Application Number Title Priority Date Filing Date
HU906341A HU906341D0 (en) 1986-10-13 1987-10-01 Process for producing peptonic derivatives modified with sugar and pharmaceutical preparatives containing these compounds as active substance
HU906340A HU906340D0 (en) 1986-10-13 1987-10-01 Synthesis in solid phase for producing peptonic alcohols
HU874432A HU206890B (en) 1986-10-13 1987-10-01 Process for producing sugar-modified somatostatin peptide derivatives and pharmaceutical compositions containing them as active components

Family Applications After (2)

Application Number Title Priority Date Filing Date
HU906340A HU906340D0 (en) 1986-10-13 1987-10-01 Synthesis in solid phase for producing peptonic alcohols
HU874432A HU206890B (en) 1986-10-13 1987-10-01 Process for producing sugar-modified somatostatin peptide derivatives and pharmaceutical compositions containing them as active components

Country Status (23)

Country Link
US (1) US5656721A (enExample)
JP (2) JPH0645639B2 (enExample)
KR (1) KR960016861B1 (enExample)
AU (2) AU617986B2 (enExample)
BE (1) BE1003752A4 (enExample)
CA (1) CA1340985C (enExample)
CH (2) CH682632A5 (enExample)
DE (1) DE3790635T1 (enExample)
DK (1) DK174337B1 (enExample)
ES (1) ES2007418A6 (enExample)
FI (1) FI874495A7 (enExample)
FR (1) FR2609991A1 (enExample)
GB (2) GB2199829B (enExample)
GR (1) GR871567B (enExample)
HU (3) HU906341D0 (enExample)
IE (1) IE912442A1 (enExample)
LU (1) LU87014A1 (enExample)
NL (1) NL194729C (enExample)
NZ (1) NZ222133A (enExample)
PL (1) PL157156B1 (enExample)
PT (1) PT85904B (enExample)
SE (2) SE8703938L (enExample)
WO (1) WO1988002756A2 (enExample)

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HU906341D0 (en) * 1986-10-13 1991-04-29 Sandoz Ag Process for producing peptonic derivatives modified with sugar and pharmaceutical preparatives containing these compounds as active substance
DE3822557C2 (de) * 1987-07-10 1998-07-02 Ciba Geigy Ag Arzneimittel, enthaltend Somatostatine
WO1989007109A1 (en) * 1988-02-01 1989-08-10 The Upjohn Company Renin inhibiting peptides with polar end groups
DK163689A (da) * 1988-04-08 1989-10-30 Sandoz Ag Peptidderivater
DE3910667A1 (de) * 1988-04-11 1989-10-19 Sandoz Ag Peptidderivate
GB8813339D0 (en) * 1988-06-06 1988-07-13 Sandoz Ltd Improvements in/relating to organic compounds
BE1003762A3 (fr) * 1988-11-11 1992-06-09 Sandoz Sa Nouvelle utilisation therapeutique de la somatostatine et de ses analogues et derives.
US5776894A (en) * 1988-12-05 1998-07-07 Novartis Ag Chelated somatostatin peptides and complexes thereof, pharmaceutical compositions containing them and their use in treating tumors
US5753627A (en) * 1988-12-05 1998-05-19 Novartis Ag Use of certain complexed somatostatin peptides for the invivo imaging of somatostatin receptor-positive tumors and metastasis
MY106120A (en) * 1988-12-05 1995-03-31 Novartis Ag Peptide derivatives.
IT1229514B (it) * 1989-01-30 1991-09-03 Farmhispania S A A Montme Glicoconiugati anfifilici sintetici per impiego neurologico.
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DE4206858A1 (de) * 1992-03-05 1993-09-09 Behringwerke Ag Glycopeptid-derivate, verfahren zu ihrer herstellung und diese verbindungen enthaltende pharmazeutische mittel
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US5508387A (en) * 1993-08-04 1996-04-16 Glycomed Incorporated Selectin binding glycopeptides
PT1288223E (pt) * 1993-08-09 2005-03-31 Sod Conseils Rech Applic Derivados de peptidos terapeuticos
US5632969A (en) * 1994-10-13 1997-05-27 Merck & Co., Inc. N3 S2 chelating ligands optionally radiolabelled with Tc or Re, useful for diagnostic or therapeutic applications
US5556939A (en) * 1994-10-13 1996-09-17 Merck Frosst Canada, Inc. TC or RE radionuclide labelled chelate, hexapeptide complexes useful for diagnostic or therapeutic applications
JP3896430B2 (ja) * 1996-07-15 2007-03-22 アークレイ株式会社 糖化アミノ化合物の製造方法
IL119029A0 (en) * 1996-08-07 1996-11-14 Yeda Res & Dev Long-acting drugs and pharamaceutical compositions comprising them
WO1998051331A1 (en) 1997-05-13 1998-11-19 Societe De Conseils De Recherches Et D'applications Scientifiques S.A. (S.C.R.A.S.) Somatostatin and somatostatin agonists for decreasing body weight
US6004928A (en) * 1997-05-13 1999-12-21 Biomeasure, Incorporated Method of treating hyperlipidemia
EP0981364B1 (en) 1997-05-13 2006-03-01 Societe De Conseils De Recherches Et D'applications Scientifiques S.A.S. Method and compositions for treating hyperlipidemia
JP4372345B2 (ja) * 1998-02-13 2009-11-25 アミリン・ファーマシューティカルズ，インコーポレイテッド 新規な混合アミリン活性化合物
US5968903A (en) * 1998-05-07 1999-10-19 Biomeasure, Incorporated Inhibition of H. pylori proliferation
US20050037490A1 (en) * 1999-10-29 2005-02-17 Lawrence Rosenberg Medium for preparing dedifferentiated cells
AU2002254691B8 (en) * 2001-04-23 2008-02-14 Mallinckrodt Inc. Tc and Re labeler radioactive glycosylated octreotide derivatives
JP3996897B2 (ja) 2001-06-08 2007-10-24 ソシエテ・ドゥ・コンセイユ・ドゥ・ルシェルシュ・エ・ダプリカーション・シャンティフィック・エス・ア・エス ソマトスタチン−ドーパミンキメラ類似体
ATE346084T1 (de) * 2002-02-27 2006-12-15 Ferring Bv Zwischenprodukte und verfahren zur herstellung von heptapeptid-oxytocinanaloga
US7772188B2 (en) 2003-01-28 2010-08-10 Ironwood Pharmaceuticals, Inc. Methods and compositions for the treatment of gastrointestinal disorders
US20070093420A1 (en) * 2005-08-26 2007-04-26 Yeomans David C Therapy procedure for drug delivery for trigeminal pain
PT1787658E (pt) 2005-11-10 2012-06-22 Chemi Spa Formulações de libertação sustentada de análogos de somatostatina inibidores da hormona do crescimento
WO2008011168A2 (en) * 2006-07-21 2008-01-24 Amgen Inc. Glycosylated peptide antagonists of the bradykinin b1 receptor
DK2118123T3 (en) 2007-01-31 2016-01-25 Dana Farber Cancer Inst Inc Stabilized p53 peptides and uses thereof
EP3159352B1 (en) 2007-03-28 2023-08-02 President and Fellows of Harvard College Stitched polypeptides
JP2010540488A (ja) 2007-09-25 2010-12-24 グリコム・アクティーゼルスカブ 糖タンパク質及びグリコシル化細胞及びそれらの調製方法
WO2009062200A1 (en) * 2007-11-09 2009-05-14 University Of Tennessee Research Foundation Anti-inflammatory quinic acid derivatives for oral administration
EP3473643A1 (en) 2008-06-12 2019-04-24 Ipsen Bioinnovation Limited Fusion proteins for use in the treatemnt of cancer
ES2750651T3 (es) 2008-06-12 2020-03-26 Ipsen Bioinnovation Ltd Proteínas de fusión para uso en el tratamiento de acromegalia
US8377891B2 (en) 2008-11-07 2013-02-19 Usv, Ltd. Process for synthesis of cyclic octapeptide
GB0820970D0 (en) 2008-11-17 2008-12-24 Syntaxin Ltd Suppression of cancer
SI2603600T1 (sl) 2010-08-13 2019-04-30 Aileron Therapeutics, Inc. Peptidomimetični makrocikli
KR102175017B1 (ko) 2011-09-04 2020-11-05 가부시키가이샤 도우사 고가쿠 겐큐쇼 당쇄 부가 폴리펩티드 및 당해 폴리펩티드를 포함하는 의약 조성물
IN2014CN02399A (enExample) 2011-09-04 2015-06-19 Glytech Inc
EP2768518A4 (en) 2011-10-18 2015-05-27 Aileron Therapeutics Inc PEPTIDOMIMETIC MACROCYCLES
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US8927500B2 (en) 2012-02-15 2015-01-06 Aileron Therapeutics, Inc. Peptidomimetic macrocycles
AU2013337388B2 (en) 2012-11-01 2018-08-02 Aileron Therapeutics, Inc. Disubstituted amino acids and methods of preparation and use thereof
DK3007704T3 (da) 2013-06-13 2021-03-29 Antisense Therapeutics Ltd Kombinationsterapi til akromegali
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AU2016205225A1 (en) 2015-01-07 2017-08-17 Trigemina, Inc. Magnesium-containing oxytocin formulations and methods of use
CN107614003A (zh) 2015-03-20 2018-01-19 艾瑞朗医疗公司 拟肽大环化合物及其用途
PL3442560T4 (pl) 2016-04-12 2025-04-28 Tonix Pharma Limited Formulacje oksytocyny zawierające magnez i sposoby zastosowania
WO2019104214A1 (en) 2017-11-22 2019-05-31 Dauntless 2, Inc. Membrane emulsification device for microsphere creation
EP3713545A1 (en) 2017-11-22 2020-09-30 Dauntless 1, Inc. Therapeutic compound formulations
WO2020005842A1 (en) 2018-06-25 2020-01-02 Dauntless 2, Inc. Membrane emulsification device with impeller for microsphere creation
CN114026107A (zh) 2019-04-16 2022-02-08 巴克姆股份公司 二硫键肽的生产
WO2021212010A2 (en) 2020-04-17 2021-10-21 The Trustees Of Indiana University Small molecule antiviral drug treatment for human papillomavirus infections
US20230399373A1 (en) * 2020-10-22 2023-12-14 The Trustees Of Indiana University Molecular designs of glucose-responsive and glucose-cleavable insulin analogues
WO2025229200A1 (en) 2024-05-03 2025-11-06 Bachem Holding Ag Manufacture of disulfide bonded peptides

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US4254023A (en) * 1979-10-16 1981-03-03 Pennwalt Corporation Synthesis of peptide alcohols by the solid phase method
US4280953A (en) * 1979-11-08 1981-07-28 The Salk Institute For Biological Studies Glycosylated analogs of somatostatin
DE19375086I2 (de) * 1979-11-27 2003-01-09 Novartis Ag Polypeptide Verfahren zu ihrer Herstellung pharmazeutische Zusammensetzungen die diese Polypeptide enthalten und ihre Verwendung
FR2522967B1 (fr) * 1982-03-15 1986-03-07 Anvar Conjugues d'haptenes et de muramyl-peptides, doues d'activite immunogene et compositions les contenant
US4444683A (en) * 1982-11-17 1984-04-24 University Of Utah Glycosylated insulin derivatives
US4483792A (en) * 1982-11-17 1984-11-20 Kim Wan S Glycosylated insulin derivatives
FR2546163B1 (fr) * 1983-05-16 1987-10-09 Centre Nat Rech Scient Nouveaux derives acyles hydrosolubles de peptides ou d'amino-acides, leur preparation et leur application
FR2548673B1 (fr) * 1983-07-05 1985-10-04 Essilor Int Polymeres supports de produits actifs relargables et leur procede de preparation
LU85269A1 (fr) * 1984-03-26 1985-10-14 Techland S A Composes nouveaux de somatostatine,procede pour leur synthese,preparation a usage veterinaire contenant lesdits composes et procede pour le traitement d'animaux
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DE3439610A1 (de) * 1984-10-30 1986-04-30 Boehringer Mannheim Gmbh, 6800 Mannheim Immunogene, verfahren zu deren herstellung sowie damit gewonnene antikoerper gegen glykosiliertes haemoglobin
FI860708A7 (fi) * 1985-02-20 1986-08-21 Ciba Geigy Ag Acylerade hexosderivat och foerfarande foer deras framstaellning.
JPS61264260A (ja) * 1985-05-17 1986-11-22 Rikagaku Kenkyusho アルデヒド化多孔性高分子材料によるタンパク質の除去方法
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JPS63165411A (ja) * 1986-09-11 1988-07-08 Tokyo Organ Chem Ind Ltd アルデヒド基を有する架橋共重合体の製法
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HU906341D0 (en) * 1986-10-13 1991-04-29 Sandoz Ag Process for producing peptonic derivatives modified with sugar and pharmaceutical preparatives containing these compounds as active substance
US4859736A (en) * 1987-03-30 1989-08-22 Ciba-Geigy Corporation Synthetic polystyrene resin and its use in solid phase peptide synthesis
CH679045A5 (enExample) * 1987-06-29 1991-12-13 Sandoz Ag

Also Published As

Publication number Publication date
SE8703938L (sv) 1988-04-14
SE518630C2 (sv) 2002-11-05
US5656721A (en) 1997-08-12
AU7956487A (en) 1988-04-14
HU206890B (en) 1993-01-28
NL194729B (nl) 2002-09-02
SE8703938D0 (sv) 1987-10-12
GB2199829A (en) 1988-07-20
FR2609991A1 (fr) 1988-07-29
GB2199831B (en) 1991-04-17
GR871567B (en) 1988-02-16
AU634664B2 (en) 1993-02-25
NL8702345A (nl) 1988-05-02
WO1988002756A2 (en) 1988-04-21
GB2199829B (en) 1991-04-17
DK532787D0 (da) 1987-10-12
KR880005153A (ko) 1988-06-28
DK532787A (da) 1988-04-14
KR960016861B1 (ko) 1996-12-23
CH682632A5 (de) 1993-10-29
JPS63101399A (ja) 1988-05-06
AU8015091A (en) 1991-10-31
JPH0314599A (ja) 1991-01-23
PL157156B1 (pl) 1992-05-29
ES2007418A6 (es) 1989-06-16
PL268173A1 (en) 1988-09-01
GB8800537D0 (en) 1988-02-10
DK174337B1 (da) 2002-12-16
IE912442L (en) 1988-04-13
FR2609991B1 (enExample) 1995-03-10
GB8723737D0 (en) 1987-11-11
JPH0645639B2 (ja) 1994-06-15
PT85904A (en) 1987-11-01
FI874495A0 (fi) 1987-10-12
CA1340985C (en) 2000-05-09
FI874495L (fi) 1988-04-14
BE1003752A4 (fr) 1992-06-09
NZ222133A (en) 1993-02-25
SE9301172D0 (sv) 1993-04-07
LU87014A1 (fr) 1988-05-03
IE912442A1 (en) 1992-02-12
CH680512A5 (enExample) 1992-09-15
WO1988002756A3 (en) 1988-07-14
GB2199831A (en) 1988-07-20
AU617986B2 (en) 1991-12-12
FI874495A7 (fi) 1988-04-14
DE3790635T1 (enExample) 1988-10-06
PT85904B (pt) 1990-08-31
HU906340D0 (en) 1991-04-29
JP2744910B2 (ja) 1998-04-28
NL194729C (nl) 2003-01-07
HUT46710A (en) 1988-11-28
SE9301172L (enExample) 1900-01-01

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