HU185009B - Process for preparing trans-2-substituted-5-aryl-2,3,4,4a,5,9b,- hexahydro-1h-pyrido/4,3-b/ indole derivatives - Google Patents

Process for preparing trans-2-substituted-5-aryl-2,3,4,4a,5,9b,- hexahydro-1h-pyrido/4,3-b/ indole derivatives Download PDF

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Publication number
HU185009B
HU185009B HU78PI626A HUPI000626A HU185009B HU 185009 B HU185009 B HU 185009B HU 78PI626 A HU78PI626 A HU 78PI626A HU PI000626 A HUPI000626 A HU PI000626A HU 185009 B HU185009 B HU 185009B
Authority
HU
Hungary
Prior art keywords
fluorophenyl
hexahydro
trans
carboline
hydrogen
Prior art date
Application number
HU78PI626A
Other languages
German (de)
English (en)
Hungarian (hu)
Inventor
Welch Williard M Ifj
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Publication of HU185009B publication Critical patent/HU185009B/hu

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/22—Anxiolytics
HU78PI626A 1977-05-23 1978-05-18 Process for preparing trans-2-substituted-5-aryl-2,3,4,4a,5,9b,- hexahydro-1h-pyrido/4,3-b/ indole derivatives HU185009B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US79939277A 1977-05-23 1977-05-23

Publications (1)

Publication Number Publication Date
HU185009B true HU185009B (en) 1984-11-28

Family

ID=25175793

Family Applications (3)

Application Number Title Priority Date Filing Date
HU822639A HU187782B (en) 1977-05-23 1978-05-18 Process for preparing trans-5-aryl-2,3,4,4a,5,9b-hexahydro-1h-pyrido-/4,3-b/indole derivatives
HU822638A HU188802B (en) 1977-05-23 1978-05-18 Process for preparing trans-2-substituted-5-aryl-2,3,4, 4a,5,9b-hexahydro-1h-pyrido/4,3-b/indole derivatives
HU78PI626A HU185009B (en) 1977-05-23 1978-05-18 Process for preparing trans-2-substituted-5-aryl-2,3,4,4a,5,9b,- hexahydro-1h-pyrido/4,3-b/ indole derivatives

Family Applications Before (2)

Application Number Title Priority Date Filing Date
HU822639A HU187782B (en) 1977-05-23 1978-05-18 Process for preparing trans-5-aryl-2,3,4,4a,5,9b-hexahydro-1h-pyrido-/4,3-b/indole derivatives
HU822638A HU188802B (en) 1977-05-23 1978-05-18 Process for preparing trans-2-substituted-5-aryl-2,3,4, 4a,5,9b-hexahydro-1h-pyrido/4,3-b/indole derivatives

Country Status (31)

Country Link
JP (1) JPS53144600A (xx)
AR (2) AR217688A1 (xx)
AT (1) AT368995B (xx)
AU (1) AU499618B1 (xx)
BE (1) BE867249A (xx)
CA (1) CA1094071A (xx)
CH (1) CH634321A5 (xx)
CS (1) CS207612B2 (xx)
DD (4) DD145536A5 (xx)
DE (1) DE2822465C2 (xx)
DK (1) DK226678A (xx)
EG (1) EG13590A (xx)
FI (1) FI63402C (xx)
FR (1) FR2392023A1 (xx)
GB (1) GB1586655A (xx)
GR (1) GR69985B (xx)
HU (3) HU187782B (xx)
IE (1) IE46975B1 (xx)
IL (1) IL54755A (xx)
IT (1) IT1096307B (xx)
LU (1) LU79684A1 (xx)
NL (1) NL7804210A (xx)
NO (2) NO150204C (xx)
NZ (1) NZ187333A (xx)
PH (1) PH13756A (xx)
PL (5) PL114547B1 (xx)
PT (1) PT68058B (xx)
SE (2) SE441448B (xx)
SU (4) SU873883A3 (xx)
YU (4) YU91478A (xx)
ZA (1) ZA782918B (xx)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4224329A (en) * 1979-01-23 1980-09-23 Pfizer Inc. 2-Substituted-trans-5-aryl-2,3,4,4a,5,9b-hexahydro-1H-pyrido[4,3-b]indoles
US4451655A (en) * 1982-05-17 1984-05-29 Pfizer Inc. Process for preparing carboline derivatives and compounds used in their preparation
RU2106864C1 (ru) * 1995-10-23 1998-03-20 Николай Серафимович Зефиров Средство для лечения болезни альцгеймера
US6974825B1 (en) 1996-12-20 2005-12-13 Astrazeneca Canada Inc. Compounds with analgesic effect
SE9604786D0 (sv) * 1996-12-20 1996-12-20 Astra Pharma Inc New compounds
SE9904675D0 (sv) 1999-12-20 1999-12-20 Astra Pharma Inc Novel compounds
SE0101769D0 (sv) 2001-05-18 2001-05-18 Astrazeneca Ab Novel compounds
SE0101771D0 (sv) 2001-05-18 2001-05-18 Astrazeneca Ab Novel compounds
SE0101773D0 (sv) 2001-05-18 2001-05-18 Astrazeneca Ab Novel compounds
SE0101770D0 (sv) 2001-05-18 2001-05-18 Astrazeneca Ab Novel compounds

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AR205452A1 (es) * 1973-12-06 1976-05-07 Endo Lab Metodo para preparar nuevos trans-2, 3, 4, 4a, 5, 9b-hexahidro-5-fenil-1h-pirido(4,3-b) indoles
JPS50126699A (xx) * 1974-03-20 1975-10-04
US4001263A (en) * 1974-04-01 1977-01-04 Pfizer Inc. 5-Aryl-1,2,3,4-tetrahydro-γ-carbolines

Also Published As

Publication number Publication date
CH634321A5 (en) 1983-01-31
PL114541B1 (en) 1981-02-28
SU843749A3 (ru) 1981-06-30
AR221721A1 (es) 1981-03-13
CS207612B2 (en) 1981-08-31
SE8305917D0 (sv) 1983-10-27
NO150204C (no) 1984-09-05
EG13590A (en) 1982-03-31
SU818484A3 (ru) 1981-03-30
YU221682A (en) 1983-01-21
FR2392023A1 (fr) 1978-12-22
GR69985B (xx) 1982-07-22
CA1094071A (en) 1981-01-20
IL54755A (en) 1981-02-27
BE867249A (fr) 1978-11-20
PL114547B1 (en) 1981-02-28
DD146186A5 (de) 1981-01-28
YU40796B (en) 1986-06-30
SE448459B (sv) 1987-02-23
AR217688A1 (es) 1980-04-15
FI63402B (fi) 1983-02-28
IT1096307B (it) 1985-08-26
LU79684A1 (fr) 1979-12-06
JPS53144600A (en) 1978-12-15
IE781013L (en) 1978-11-23
ATA369678A (de) 1982-04-15
YU221782A (en) 1983-01-21
FI63402C (fi) 1983-06-10
PT68058B (en) 1979-10-24
NO151862B (no) 1985-03-11
JPS5711912B2 (xx) 1982-03-08
PL206903A1 (pl) 1979-10-22
SE7803625L (sv) 1978-11-24
NO781770L (no) 1978-11-24
HU187782B (en) 1986-02-28
DD138321A5 (de) 1979-10-24
FI781612A (fi) 1978-11-24
DE2822465C2 (de) 1986-08-28
SU873883A3 (ru) 1981-10-15
SE441448B (sv) 1985-10-07
AU499618B1 (en) 1979-04-26
NO151862C (no) 1985-06-19
SU841589A3 (ru) 1981-06-23
GB1586655A (en) 1981-03-25
NZ187333A (en) 1984-05-31
AT368995B (de) 1982-11-25
DK226678A (da) 1978-11-24
NO150204B (no) 1984-05-28
PL117107B1 (en) 1981-07-31
PL116944B1 (en) 1981-07-31
IE46975B1 (en) 1983-11-16
IL54755A0 (en) 1978-07-31
DE2822465A1 (de) 1978-11-30
PT68058A (en) 1978-06-01
FR2392023B1 (xx) 1980-11-07
HU188802B (en) 1986-05-28
DD145536A5 (de) 1980-12-17
YU221882A (en) 1983-01-21
YU91478A (en) 1983-01-21
SE8305917L (sv) 1983-10-27
ZA782918B (en) 1979-06-27
PH13756A (en) 1980-09-17
IT7823673A0 (it) 1978-05-22
NL7804210A (nl) 1978-11-27
NO831790L (no) 1978-11-24
DD145537A5 (de) 1980-12-17

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