HRP921128B1 - Novel process for the preparation of 4-methyl-5(2-chloroethyl)-thiazole and analogues thereof - Google Patents

Novel process for the preparation of 4-methyl-5(2-chloroethyl)-thiazole and analogues thereof

Info

Publication number
HRP921128B1
HRP921128B1 HR1125/92A HRP921128A HRP921128B1 HR P921128 B1 HRP921128 B1 HR P921128B1 HR 1125/92 A HR1125/92 A HR 1125/92A HR P921128 A HRP921128 A HR P921128A HR P921128 B1 HRP921128 B1 HR P921128B1
Authority
HR
Croatia
Prior art keywords
chloro
alkyl
methyl
thiazole
general formula
Prior art date
Application number
HR1125/92A
Other languages
English (en)
Inventor
Sandor Garaczy
Original Assignee
Sandor Garaczy
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from HU3402/91A external-priority patent/HU215840B/hu
Priority claimed from HU913404A external-priority patent/HU207724B/hu
Priority claimed from HU3403/91A external-priority patent/HU215850B/hu
Priority claimed from HU9201125A external-priority patent/HUT66222A/hu
Priority claimed from HUP9201124A external-priority patent/HU215849B/hu
Application filed by Sandor Garaczy filed Critical Sandor Garaczy
Publication of HRP921128A2 publication Critical patent/HRP921128A2/xx
Publication of HRP921128B1 publication Critical patent/HRP921128B1/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/22—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C331/00—Derivatives of thiocyanic acid or of isothiocyanic acid
    • C07C331/02—Thiocyanates
    • C07C331/04—Thiocyanates having sulfur atoms of thiocyanate groups bound to acyclic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/32—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/32—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D277/34—Oxygen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
HR1125/92A 1991-10-30 1992-10-29 Novel process for the preparation of 4-methyl-5(2-chloroethyl)-thiazole and analogues thereof HRP921128B1 (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
HU3402/91A HU215840B (hu) 1991-10-30 1991-10-30 Eljárás 2-klór-tiazol-származékok előállítására
HU913404A HU207724B (en) 1991-10-30 1991-10-30 New process for producing thiazols
HU3403/91A HU215850B (hu) 1991-10-30 1991-10-30 Eljárás tiocianáto-keton-származékok előállítására
HU9201125A HUT66222A (en) 1992-04-03 1992-04-03 2-hydroxy-4-methyl-5-halogenoalkyl-1,3-thiazole derivatives and process for producing them
HUP9201124A HU215849B (hu) 1992-04-03 1992-04-03 Eljárás 2-klór-4-metil-5-(halogén-alkil)-1,3-tiazol-származékok előállítására

Publications (2)

Publication Number Publication Date
HRP921128A2 HRP921128A2 (en) 1995-10-31
HRP921128B1 true HRP921128B1 (en) 1998-10-31

Family

ID=27517525

Family Applications (1)

Application Number Title Priority Date Filing Date
HR1125/92A HRP921128B1 (en) 1991-10-30 1992-10-29 Novel process for the preparation of 4-methyl-5(2-chloroethyl)-thiazole and analogues thereof

Country Status (24)

Country Link
US (2) US5648498A (sv)
EP (2) EP0619815B1 (sv)
JP (1) JP3190959B2 (sv)
KR (1) KR100218131B1 (sv)
AT (1) ATE151761T1 (sv)
AU (1) AU664868B2 (sv)
CA (1) CA2121488A1 (sv)
CZ (1) CZ283402B6 (sv)
DE (1) DE69219154T2 (sv)
DK (1) DK0619815T3 (sv)
ES (1) ES2100365T3 (sv)
FI (1) FI105476B (sv)
GR (1) GR3023842T3 (sv)
HK (1) HK93397A (sv)
HR (1) HRP921128B1 (sv)
HU (1) HU217079B (sv)
IL (1) IL103586A (sv)
IS (1) IS1688B (sv)
LV (1) LV12130B (sv)
NO (1) NO304650B1 (sv)
PL (1) PL172013B1 (sv)
SI (1) SI9200292B (sv)
SK (1) SK279665B6 (sv)
WO (1) WO1993009107A1 (sv)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19548417A1 (de) * 1995-12-22 1997-06-26 Bayer Ag Verfahren zur Herstellung von 2-Chlor-5-chlormethylthiazol
HUP0900267A2 (en) 2009-04-30 2011-03-28 Sanofi Aventis Process for preparing of thiazole amines and intermediates thereof

Family Cites Families (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US1808893A (en) * 1931-06-09 Leon c
GB456751A (en) * 1935-05-13 1936-11-13 Ig Farbenindustrie Ag Process for the manufacture of 4-alkyl-5-hydroxy-alkylthiazoles
CH200248A (de) * 1937-03-12 1938-09-30 Hoffmann La Roche Verfahren zur Darstellung von 4-Methyl-5-B-chloräthylthiazol.
US2395453A (en) * 1944-02-26 1946-02-26 Rohm & Haas Beta-thiocyano ketones and method for their preparation
FR1274353A (fr) * 1955-09-28 1961-10-27 Procédé de préparation des méthyl-4 bêta-halogénoéthyl-5 thiazoles et de leurs sels
DE1082903B (de) * 1957-10-11 1960-06-09 Basf Ag Verfahren zur Herstellung von Rhodanverbindungen
DE1515197C3 (de) * 1964-05-06 1974-08-15 Steigerwald Strahltechnik Gmbh, 8000 Muenchen Energiestrahl-Schweiß verfahren
BE668231A (sv) * 1964-08-12
US3670004A (en) * 1969-01-07 1972-06-13 Buckman Labor Inc Thiocyano substituted acrylates and propionates and their use as pesticides
FR2152345A1 (en) * 1971-09-06 1973-04-27 Roussel Uclaf Alpha-(2-thiazolyl)oxyalkanoic acids and derivatives - - with analgesic,antiinflammatory and antipyretic activity
DE2236796A1 (de) * 1972-07-27 1974-02-07 Georg Dipl Chem Dr Herbertz 2-hydroxy-4-methyl-5-(2-chloraethyl)thiazol
DE2423981A1 (de) * 1974-05-17 1975-11-27 Bayer Ag Alpha - halogenketone
DE2339109A1 (de) * 1973-08-02 1975-02-20 Bayer Ag Alpha-halogenketone
DE2823658A1 (de) * 1978-05-30 1979-12-06 Bayer Ag Mittel zur bekaempfung von pflanzenbakteriosen
US4377693A (en) * 1979-10-01 1983-03-22 Monsanto Company 2-Chloro-4,5-disubstituted-thiazoles useful as herbicidal safeners
US4284426A (en) * 1979-10-01 1981-08-18 Monsanto Company 2-Chloro-4,5-disubstituted-thiazoles useful as herbicidal safeners
US4284784A (en) * 1980-05-22 1981-08-18 Merck & Co., Inc. Process for the preparation of 4-methyl thiazole
SU943233A1 (ru) * 1980-07-18 1982-07-15 Ереванский государственный университет @ -Роданвинилметилкетон в качестве мономера дл синтеза ионитов и полиэлектролитов и способ его получени
GB8705447D0 (en) * 1987-03-09 1987-04-15 Autopia Terakat Accessories Lt Glass frail
US4822813A (en) * 1987-03-11 1989-04-18 Uniroyal Chemical Ltd./Uniroyal Chemical Ltee 3-(2-Haloalkyl)-1,4-oxathiins and 2-(2-haloalkyl)-1,4-dithiins, and treatment of leukemia and tumors therewith
SE8900564D0 (sv) * 1989-02-17 1989-02-17 Astra Ab Novel medicinal use
US5180833A (en) * 1990-03-16 1993-01-19 Takeda Chemical Industries, Ltd. Process for the preparation of chlorothiazole derivatives
HU206198B (en) * 1990-09-21 1992-09-28 Egyt Gyogyszervegyeszeti Gyar Process for producing rhodanidoisobutyric acid

Also Published As

Publication number Publication date
HUT70739A (en) 1995-10-30
JPH07503233A (ja) 1995-04-06
NO941567L (sv) 1994-06-22
CZ103494A3 (en) 1995-11-15
US5534644A (en) 1996-07-09
DE69219154T2 (de) 1997-07-24
ES2100365T3 (es) 1997-06-16
FI941996A (sv) 1994-04-29
SK50194A3 (en) 1995-02-08
SI9200292A (en) 1993-06-30
SK279665B6 (sk) 1999-02-11
EP0619815B1 (en) 1997-04-16
IS3937A (is) 1993-05-01
ATE151761T1 (de) 1997-05-15
SI9200292B (sl) 1999-06-30
EP0619815A1 (en) 1994-10-19
LV12130B (en) 1999-02-20
PL172013B1 (pl) 1997-07-31
IL103586A (en) 1997-09-30
GR3023842T3 (en) 1997-09-30
DE69219154D1 (de) 1997-05-22
WO1993009107A1 (en) 1993-05-13
HRP921128A2 (en) 1995-10-31
HK93397A (en) 1997-08-01
NO304650B1 (no) 1999-01-25
CZ283402B6 (cs) 1998-04-15
EP0546306A1 (en) 1993-06-16
FI105476B (sv) 2000-08-31
AU664868B2 (en) 1995-12-07
DK0619815T3 (da) 1997-09-01
CA2121488A1 (en) 1993-05-13
US5648498A (en) 1997-07-15
EP0546306B1 (en) 1997-04-16
KR100218131B1 (ko) 1999-09-01
IL103586A0 (en) 1993-03-15
NO941567D0 (sv) 1994-04-28
AU2912392A (en) 1993-06-07
HU217079B (hu) 1999-11-29
IS1688B (is) 1998-04-20
LV12130A (lv) 1998-09-20
FI941996A0 (sv) 1994-04-29
HU9401262D0 (en) 1994-08-29
JP3190959B2 (ja) 2001-07-23

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FI905788A0 (sv) Förfarande för framställning av terapeutiskt användbara 6-aryl-5,6-dihydroimidazo/2,1-b/tiazolderivat
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