HRP20040825A2 - Indazoles substituted with an anti-cancerous activity - Google Patents

Indazoles substituted with an anti-cancerous activity Download PDF

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Publication number
HRP20040825A2
HRP20040825A2 HR20040825A HRP20040825A HRP20040825A2 HR P20040825 A2 HRP20040825 A2 HR P20040825A2 HR 20040825 A HR20040825 A HR 20040825A HR P20040825 A HRP20040825 A HR P20040825A HR P20040825 A2 HRP20040825 A2 HR P20040825A2
Authority
HR
Croatia
Prior art keywords
indazol
benzenesulfonamide
phenyl
methanesulfonyl
methylsulfonyl
Prior art date
Application number
HR20040825A
Other languages
English (en)
Croatian (hr)
Inventor
Damour Dominique
Carry Jean-Christophe
Nemecek Patrick
Terrier Corinne
Nardi Frederico
Filoche Bruno
Cherrier Marie-Pierre
Bezard Daniel
Original Assignee
Aventis Pharma S.A.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Aventis Pharma S.A. filed Critical Aventis Pharma S.A.
Publication of HRP20040825A2 publication Critical patent/HRP20040825A2/hr

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/54—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings condensed with carbocyclic rings or ring systems
    • C07D231/56—Benzopyrazoles; Hydrogenated benzopyrazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond

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  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Cosmetics (AREA)
HR20040825A 2002-03-11 2003-03-07 Indazoles substituted with an anti-cancerous activity HRP20040825A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR0202996A FR2836914B1 (fr) 2002-03-11 2002-03-11 Indazoles substitues, compositions les contenant, procede de fabrication et utilisation
PCT/FR2003/000751 WO2003078402A1 (fr) 2002-03-11 2003-03-07 Indazoles substitues avec une activite anticancereuse

Publications (1)

Publication Number Publication Date
HRP20040825A2 true HRP20040825A2 (en) 2005-06-30

Family

ID=27763684

Family Applications (1)

Application Number Title Priority Date Filing Date
HR20040825A HRP20040825A2 (en) 2002-03-11 2003-03-07 Indazoles substituted with an anti-cancerous activity

Country Status (29)

Country Link
US (2) US6858638B2 (cg-RX-API-DMAC7.html)
EP (1) EP1487803A1 (cg-RX-API-DMAC7.html)
JP (1) JP4643910B2 (cg-RX-API-DMAC7.html)
KR (1) KR20040091128A (cg-RX-API-DMAC7.html)
CN (1) CN100369899C (cg-RX-API-DMAC7.html)
AR (1) AR038914A1 (cg-RX-API-DMAC7.html)
AU (1) AU2003242808B2 (cg-RX-API-DMAC7.html)
BR (1) BR0308339A (cg-RX-API-DMAC7.html)
CA (1) CA2478540A1 (cg-RX-API-DMAC7.html)
EC (1) ECSP045286A (cg-RX-API-DMAC7.html)
FR (1) FR2836914B1 (cg-RX-API-DMAC7.html)
GT (1) GT200300031A (cg-RX-API-DMAC7.html)
HN (1) HN2003000094A (cg-RX-API-DMAC7.html)
HR (1) HRP20040825A2 (cg-RX-API-DMAC7.html)
IL (2) IL163805A0 (cg-RX-API-DMAC7.html)
MA (1) MA27176A1 (cg-RX-API-DMAC7.html)
MX (1) MXPA04008446A (cg-RX-API-DMAC7.html)
NO (1) NO20044261L (cg-RX-API-DMAC7.html)
OA (1) OA12784A (cg-RX-API-DMAC7.html)
PA (1) PA8566701A1 (cg-RX-API-DMAC7.html)
PE (1) PE20040071A1 (cg-RX-API-DMAC7.html)
PL (1) PL372389A1 (cg-RX-API-DMAC7.html)
RU (1) RU2004130280A (cg-RX-API-DMAC7.html)
SV (1) SV2003001493A (cg-RX-API-DMAC7.html)
TN (1) TNSN04175A1 (cg-RX-API-DMAC7.html)
TW (1) TW200303863A (cg-RX-API-DMAC7.html)
UY (1) UY27712A1 (cg-RX-API-DMAC7.html)
WO (1) WO2003078402A1 (cg-RX-API-DMAC7.html)
ZA (1) ZA200406730B (cg-RX-API-DMAC7.html)

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US9034875B2 (en) 2009-05-26 2015-05-19 Abbvie Inc. Apoptosis-inducing agents for the treatment of cancer and immune and autoimmune diseases
WO2011050245A1 (en) * 2009-10-23 2011-04-28 Yangbo Feng Bicyclic heteroaryls as kinase inhibitors
CN102247361B (zh) * 2010-05-20 2015-04-29 中国医学科学院药物研究所 5-硝基-1氢-吲唑-3-腈在制备药物中的应用
SG10201801794WA (en) 2010-10-29 2018-04-27 Abbvie Inc Solid dispersions containing an apoptosis-inducing agent
UA113500C2 (xx) 2010-10-29 2017-02-10 Одержані екструзією розплаву тверді дисперсії, що містять індукуючий апоптоз засіб
NZ610151A (en) 2010-11-23 2015-06-26 Abbvie Inc Salts and crystalline forms of an apoptosis-inducing agent
PH12013501006A1 (en) 2010-11-23 2022-03-30 Abbvie Ireland Unlimited Co Methods of treatment using selective bcl-2 inhibitors
US20140275082A1 (en) 2013-03-14 2014-09-18 Abbvie Inc. Apoptosis-inducing agents for the treatment of cancer and immune and autoimmune diseases
EP3215156B1 (en) 2014-11-03 2025-09-24 Iomet Pharma Ltd. Inhibitors of tryptophan-2,3-dioxygenase or indoleamine-2,3-dioxygenase
GB201511382D0 (en) 2015-06-29 2015-08-12 Imp Innovations Ltd Novel compounds and their use in therapy
CN111278437A (zh) * 2017-07-21 2020-06-12 卡德门企业有限公司 Rho相关含卷曲螺旋蛋白激酶的抑制剂
WO2019046467A1 (en) 2017-08-29 2019-03-07 Rutgers, The State University Of New Jersey INDAZOLES THERAPEUTIC
JP2025504415A (ja) * 2022-01-12 2025-02-12 アイエフエム デュー インコーポレイテッド Ｓｔｉｎｇ活性に関連する病態を治療するための化合物及び組成物
EP4488275A4 (en) 2022-03-04 2025-07-23 Shanghai Yingli Pharm Co Ltd COMPOUND CONTAINING A FIVE-MEMBERED HETEROAROMATIC RING STRUCTURE, PHARMACEUTICAL COMPOSITION AND USE THEREOF
CN114605329B (zh) * 2022-03-28 2024-01-26 河南中医药大学 取代的吲唑甲酰胺或取代的氮杂吲唑甲酰胺类flt3抑制剂及其用途
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Also Published As

Publication number Publication date
ZA200406730B (en) 2005-08-24
JP2005533004A (ja) 2005-11-04
TNSN04175A1 (fr) 2007-03-12
US20040106667A1 (en) 2004-06-03
US7473701B2 (en) 2009-01-06
MXPA04008446A (es) 2004-12-06
IL163805A0 (en) 2005-12-18
PA8566701A1 (es) 2003-12-10
UY27712A1 (es) 2003-09-30
GT200300031A (es) 2006-05-26
AU2003242808B2 (en) 2008-09-18
BR0308339A (pt) 2005-02-01
WO2003078402A1 (fr) 2003-09-25
FR2836914B1 (fr) 2008-03-14
SV2003001493A (es) 2003-07-10
FR2836914A1 (fr) 2003-09-12
JP4643910B2 (ja) 2011-03-02
US6858638B2 (en) 2005-02-22
ECSP045286A (es) 2004-10-26
MA27176A1 (fr) 2005-01-03
AU2003242808A1 (en) 2003-09-29
US20050059722A1 (en) 2005-03-17
TW200303863A (en) 2003-09-16
NO20044261L (no) 2004-11-25
HN2003000094A (es) 2003-12-15
PL372389A1 (en) 2005-07-25
AR038914A1 (es) 2005-02-02
CN100369899C (zh) 2008-02-20
PE20040071A1 (es) 2004-02-13
CN1642922A (zh) 2005-07-20
KR20040091128A (ko) 2004-10-27
OA12784A (fr) 2006-07-10
EP1487803A1 (fr) 2004-12-22
IL163805A (en) 2009-08-03
CA2478540A1 (fr) 2003-09-25
RU2004130280A (ru) 2005-06-27

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