PL372389A1 - Indazoles substituted with an anti-cancerous activity - Google Patents

Indazoles substituted with an anti-cancerous activity

Info

Publication number
PL372389A1
PL372389A1 PL03372389A PL37238903A PL372389A1 PL 372389 A1 PL372389 A1 PL 372389A1 PL 03372389 A PL03372389 A PL 03372389A PL 37238903 A PL37238903 A PL 37238903A PL 372389 A1 PL372389 A1 PL 372389A1
Authority
PL
Poland
Prior art keywords
cancerous activity
indazoles substituted
indazoles
substituted
cancerous
Prior art date
Application number
PL03372389A
Other languages
English (en)
Polish (pl)
Inventor
Dominique Damour
Jean-Christophe Carry
Patrick Nemecek
Corinne Terrier
Frederico Nardi
Bruno Filoche
Marie-Pierre Cherrier
Daniel Bezard
Original Assignee
Aventis Pharma S.A.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Aventis Pharma S.A. filed Critical Aventis Pharma S.A.
Publication of PL372389A1 publication Critical patent/PL372389A1/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/54—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings condensed with carbocyclic rings or ring systems
    • C07D231/56—Benzopyrazoles; Hydrogenated benzopyrazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Cosmetics (AREA)
PL03372389A 2002-03-11 2003-03-07 Indazoles substituted with an anti-cancerous activity PL372389A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR0202996A FR2836914B1 (fr) 2002-03-11 2002-03-11 Indazoles substitues, compositions les contenant, procede de fabrication et utilisation

Publications (1)

Publication Number Publication Date
PL372389A1 true PL372389A1 (en) 2005-07-25

Family

ID=27763684

Family Applications (1)

Application Number Title Priority Date Filing Date
PL03372389A PL372389A1 (en) 2002-03-11 2003-03-07 Indazoles substituted with an anti-cancerous activity

Country Status (29)

Country Link
US (2) US6858638B2 (cg-RX-API-DMAC7.html)
EP (1) EP1487803A1 (cg-RX-API-DMAC7.html)
JP (1) JP4643910B2 (cg-RX-API-DMAC7.html)
KR (1) KR20040091128A (cg-RX-API-DMAC7.html)
CN (1) CN100369899C (cg-RX-API-DMAC7.html)
AR (1) AR038914A1 (cg-RX-API-DMAC7.html)
AU (1) AU2003242808B2 (cg-RX-API-DMAC7.html)
BR (1) BR0308339A (cg-RX-API-DMAC7.html)
CA (1) CA2478540A1 (cg-RX-API-DMAC7.html)
EC (1) ECSP045286A (cg-RX-API-DMAC7.html)
FR (1) FR2836914B1 (cg-RX-API-DMAC7.html)
GT (1) GT200300031A (cg-RX-API-DMAC7.html)
HN (1) HN2003000094A (cg-RX-API-DMAC7.html)
HR (1) HRP20040825A2 (cg-RX-API-DMAC7.html)
IL (2) IL163805A0 (cg-RX-API-DMAC7.html)
MA (1) MA27176A1 (cg-RX-API-DMAC7.html)
MX (1) MXPA04008446A (cg-RX-API-DMAC7.html)
NO (1) NO20044261L (cg-RX-API-DMAC7.html)
OA (1) OA12784A (cg-RX-API-DMAC7.html)
PA (1) PA8566701A1 (cg-RX-API-DMAC7.html)
PE (1) PE20040071A1 (cg-RX-API-DMAC7.html)
PL (1) PL372389A1 (cg-RX-API-DMAC7.html)
RU (1) RU2004130280A (cg-RX-API-DMAC7.html)
SV (1) SV2003001493A (cg-RX-API-DMAC7.html)
TN (1) TNSN04175A1 (cg-RX-API-DMAC7.html)
TW (1) TW200303863A (cg-RX-API-DMAC7.html)
UY (1) UY27712A1 (cg-RX-API-DMAC7.html)
WO (1) WO2003078402A1 (cg-RX-API-DMAC7.html)
ZA (1) ZA200406730B (cg-RX-API-DMAC7.html)

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GB0330043D0 (en) * 2003-12-24 2004-01-28 Pharmacia Italia Spa Pyrrolo [2,3-b] pyridine derivatives active as kinase inhibitors process for their preparation and pharmaceutical compositions comprising them
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SE0402763D0 (sv) * 2004-11-11 2004-11-11 Astrazeneca Ab Nitro indazole derivatives
SE0402762D0 (sv) * 2004-11-11 2004-11-11 Astrazeneca Ab Indazole sulphonamide derivatives
WO2007023114A1 (en) * 2005-08-25 2007-03-01 F. Hoffmann-La Roche Ag P38 map kinase inhibitors and methods for using the same
US8119655B2 (en) 2005-10-07 2012-02-21 Takeda Pharmaceutical Company Limited Kinase inhibitors
NZ570846A (en) 2006-01-31 2011-08-26 Array Biopharma Inc Kinase inhibitors and methods of use thereof
US20100120717A1 (en) 2006-10-09 2010-05-13 Brown Jason W Kinase inhibitors
JP2010505961A (ja) * 2006-10-09 2010-02-25 タケダ サン ディエゴ インコーポレイテッド キナーゼ阻害剤
WO2008063888A2 (en) * 2006-11-22 2008-05-29 Plexxikon, Inc. Compounds modulating c-fms and/or c-kit activity and uses therefor
FR2917735B1 (fr) * 2007-06-21 2009-09-04 Sanofi Aventis Sa Nouveaux indazoles substitutes, leur preparation et leur utilisation en therapeutique
EP2170834B1 (en) * 2007-07-16 2014-01-08 AbbVie Inc. Indazoles, benzisoxazoles and benzisothiazoles as inhibitors of protein kinases
US8546399B2 (en) 2009-05-26 2013-10-01 Abbvie Inc. Apoptosis inducing agents for the treatment of cancer and immune and autoimmune diseases
US20220315555A1 (en) 2009-05-26 2022-10-06 Abbvie Inc. Apoptosis inducing agents for the treatment of cancer and immune and autoimmune diseases
MX339469B (es) * 2009-05-26 2016-05-27 Abbvie Bahamas Ltd Agentes inductores de apotosis para el tratamiento de cancer y enfermedades inmunes y autoinmunes.
US9034875B2 (en) 2009-05-26 2015-05-19 Abbvie Inc. Apoptosis-inducing agents for the treatment of cancer and immune and autoimmune diseases
WO2011050245A1 (en) * 2009-10-23 2011-04-28 Yangbo Feng Bicyclic heteroaryls as kinase inhibitors
CN102247361B (zh) * 2010-05-20 2015-04-29 中国医学科学院药物研究所 5-硝基-1氢-吲唑-3-腈在制备药物中的应用
SG10201801794WA (en) 2010-10-29 2018-04-27 Abbvie Inc Solid dispersions containing an apoptosis-inducing agent
UA113500C2 (xx) 2010-10-29 2017-02-10 Одержані екструзією розплаву тверді дисперсії, що містять індукуючий апоптоз засіб
NZ610151A (en) 2010-11-23 2015-06-26 Abbvie Inc Salts and crystalline forms of an apoptosis-inducing agent
PH12013501006A1 (en) 2010-11-23 2022-03-30 Abbvie Ireland Unlimited Co Methods of treatment using selective bcl-2 inhibitors
US20140275082A1 (en) 2013-03-14 2014-09-18 Abbvie Inc. Apoptosis-inducing agents for the treatment of cancer and immune and autoimmune diseases
EP3215156B1 (en) 2014-11-03 2025-09-24 Iomet Pharma Ltd. Inhibitors of tryptophan-2,3-dioxygenase or indoleamine-2,3-dioxygenase
GB201511382D0 (en) 2015-06-29 2015-08-12 Imp Innovations Ltd Novel compounds and their use in therapy
CN111278437A (zh) * 2017-07-21 2020-06-12 卡德门企业有限公司 Rho相关含卷曲螺旋蛋白激酶的抑制剂
WO2019046467A1 (en) 2017-08-29 2019-03-07 Rutgers, The State University Of New Jersey INDAZOLES THERAPEUTIC
JP2025504415A (ja) * 2022-01-12 2025-02-12 アイエフエム デュー インコーポレイテッド Ｓｔｉｎｇ活性に関連する病態を治療するための化合物及び組成物
EP4488275A4 (en) 2022-03-04 2025-07-23 Shanghai Yingli Pharm Co Ltd COMPOUND CONTAINING A FIVE-MEMBERED HETEROAROMATIC RING STRUCTURE, PHARMACEUTICAL COMPOSITION AND USE THEREOF
CN114605329B (zh) * 2022-03-28 2024-01-26 河南中医药大学 取代的吲唑甲酰胺或取代的氮杂吲唑甲酰胺类flt3抑制剂及其用途
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WO2025117661A1 (en) * 2023-11-28 2025-06-05 Quantx Biosciences Us, Inc. Bicyclic heteroaryl compounds

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CO5170498A1 (es) * 1999-05-28 2002-06-27 Abbott Lab Biaril sulfonamidas son utiles como inhibidores de proliferacion celular
YU54202A (sh) 2000-01-18 2006-01-16 Agouron Pharmaceuticals Inc. Jedinjenja indazola, farmaceutske smeše i postupci za stimulisanje i inhibiranje ćelijske proliferacije
KR100423899B1 (ko) * 2000-05-10 2004-03-24 주식회사 엘지생명과학 세포 증식 억제제로 유용한 1,1-디옥소이소티아졸리딘을갖는 인다졸
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JPWO2002100833A1 (ja) 2001-06-12 2004-09-24 住友製薬株式会社 Ｒｈｏキナーゼ阻害剤
EP1401831A1 (en) * 2001-07-03 2004-03-31 Chiron Corporation Indazole benzimidazole compounds as tyrosine and serine/threonine kinase inhibitors
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FR2836915B1 (fr) 2002-03-11 2008-01-11 Aventis Pharma Sa Derives d'aminoindazoles, procede de preparation et intermediaires de ce procede a titre de medicaments et compositions pharmaceutiques les renfermant

Also Published As

Publication number Publication date
ZA200406730B (en) 2005-08-24
JP2005533004A (ja) 2005-11-04
TNSN04175A1 (fr) 2007-03-12
US20040106667A1 (en) 2004-06-03
US7473701B2 (en) 2009-01-06
MXPA04008446A (es) 2004-12-06
IL163805A0 (en) 2005-12-18
PA8566701A1 (es) 2003-12-10
UY27712A1 (es) 2003-09-30
GT200300031A (es) 2006-05-26
AU2003242808B2 (en) 2008-09-18
BR0308339A (pt) 2005-02-01
WO2003078402A1 (fr) 2003-09-25
FR2836914B1 (fr) 2008-03-14
SV2003001493A (es) 2003-07-10
FR2836914A1 (fr) 2003-09-12
JP4643910B2 (ja) 2011-03-02
US6858638B2 (en) 2005-02-22
ECSP045286A (es) 2004-10-26
MA27176A1 (fr) 2005-01-03
AU2003242808A1 (en) 2003-09-29
US20050059722A1 (en) 2005-03-17
TW200303863A (en) 2003-09-16
NO20044261L (no) 2004-11-25
HN2003000094A (es) 2003-12-15
AR038914A1 (es) 2005-02-02
HRP20040825A2 (en) 2005-06-30
CN100369899C (zh) 2008-02-20
PE20040071A1 (es) 2004-02-13
CN1642922A (zh) 2005-07-20
KR20040091128A (ko) 2004-10-27
OA12784A (fr) 2006-07-10
EP1487803A1 (fr) 2004-12-22
IL163805A (en) 2009-08-03
CA2478540A1 (fr) 2003-09-25
RU2004130280A (ru) 2005-06-27

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