HN2003000094A - Indazoles subtituidos, composiciones que los contienen, procedimiento de fabricacion y utilizacion. - Google Patents

Indazoles subtituidos, composiciones que los contienen, procedimiento de fabricacion y utilizacion.

Info

Publication number
HN2003000094A
HN2003000094A HN2003000094A HN2003000094A HN2003000094A HN 2003000094 A HN2003000094 A HN 2003000094A HN 2003000094 A HN2003000094 A HN 2003000094A HN 2003000094 A HN2003000094 A HN 2003000094A HN 2003000094 A HN2003000094 A HN 2003000094A
Authority
HN
Honduras
Prior art keywords
indazols
compositions
subtituted
contain
manufacturing
Prior art date
Application number
HN2003000094A
Other languages
English (en)
Original Assignee
Aventis Pharma Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Aventis Pharma Sa filed Critical Aventis Pharma Sa
Publication of HN2003000094A publication Critical patent/HN2003000094A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/54—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings condensed with carbocyclic rings or ring systems
    • C07D231/56—Benzopyrazoles; Hydrogenated benzopyrazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond

Abstract

LA PRESENTE INVENCION SE REFIERE, PRINCIPALMENTE A NUEVOS COMPUESTOS QUIMICOS PARTICULARMENTE A NUEVOS INDAZOLES SUBSTITUIDOS, A LAS COMPOSICIONES QUE LOS CONTIENEN Y A SU UTILIZACION COMO MEDICAMENTOS.
HN2003000094A 2002-03-11 2003-03-10 Indazoles subtituidos, composiciones que los contienen, procedimiento de fabricacion y utilizacion. HN2003000094A (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR0202996A FR2836914B1 (fr) 2002-03-11 2002-03-11 Indazoles substitues, compositions les contenant, procede de fabrication et utilisation

Publications (1)

Publication Number Publication Date
HN2003000094A true HN2003000094A (es) 2003-12-15

Family

ID=27763684

Family Applications (1)

Application Number Title Priority Date Filing Date
HN2003000094A HN2003000094A (es) 2002-03-11 2003-03-10 Indazoles subtituidos, composiciones que los contienen, procedimiento de fabricacion y utilizacion.

Country Status (29)

Country Link
US (2) US6858638B2 (es)
EP (1) EP1487803A1 (es)
JP (1) JP4643910B2 (es)
KR (1) KR20040091128A (es)
CN (1) CN100369899C (es)
AR (1) AR038914A1 (es)
AU (1) AU2003242808B2 (es)
BR (1) BR0308339A (es)
CA (1) CA2478540A1 (es)
EC (1) ECSP045286A (es)
FR (1) FR2836914B1 (es)
GT (1) GT200300031A (es)
HN (1) HN2003000094A (es)
HR (1) HRP20040825A2 (es)
IL (2) IL163805A0 (es)
MA (1) MA27176A1 (es)
MX (1) MXPA04008446A (es)
NO (1) NO20044261L (es)
OA (1) OA12784A (es)
PA (1) PA8566701A1 (es)
PE (1) PE20040071A1 (es)
PL (1) PL372389A1 (es)
RU (1) RU2004130280A (es)
SV (1) SV2003001493A (es)
TN (1) TNSN04175A1 (es)
TW (1) TW200303863A (es)
UY (1) UY27712A1 (es)
WO (1) WO2003078402A1 (es)
ZA (1) ZA200406730B (es)

Families Citing this family (40)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2836914B1 (fr) * 2002-03-11 2008-03-14 Aventis Pharma Sa Indazoles substitues, compositions les contenant, procede de fabrication et utilisation
GB0218625D0 (en) * 2002-08-10 2002-09-18 Astex Technology Ltd Pharmaceutical compounds
US7262200B2 (en) 2002-10-25 2007-08-28 Vertex Pharmaceuticals Incorporated Indazolinone compositions useful as kinase inhibitors
US7135575B2 (en) 2003-03-03 2006-11-14 Array Biopharma, Inc. P38 inhibitors and methods of use thereof
WO2005014554A1 (en) * 2003-08-08 2005-02-17 Astex Therapeutics Limited 1h-indazole-3-carboxamide compounds as mapkap kinase modulators
FR2864084B1 (fr) * 2003-12-17 2006-02-10 Aventis Pharma Sa Nouveaux derives organophosphores des indazoles et leur utilisation comme medicaments
WO2005061519A1 (en) * 2003-12-19 2005-07-07 Takeda San Diego, Inc. Kinase inhibitors
GB0330042D0 (en) * 2003-12-24 2004-01-28 Pharmacia Italia Spa Pyrrolo [2,3-b] pyridine derivatives active as kinase inhibitors process for their preparation and pharmaceutical compositions them
GB0330043D0 (en) * 2003-12-24 2004-01-28 Pharmacia Italia Spa Pyrrolo [2,3-b] pyridine derivatives active as kinase inhibitors process for their preparation and pharmaceutical compositions comprising them
US20050250829A1 (en) * 2004-04-23 2005-11-10 Takeda San Diego, Inc. Kinase inhibitors
JP2008510734A (ja) * 2004-08-18 2008-04-10 タケダ サン ディエゴ インコーポレイテッド キナーゼ阻害剤
PT1797042E (pt) * 2004-09-29 2009-02-12 Hoffmann La Roche Derivados de indozolona como inibidores de 11b-hsd1
US7713973B2 (en) 2004-10-15 2010-05-11 Takeda Pharmaceutical Company Limited Kinase inhibitors
SE0402763D0 (sv) * 2004-11-11 2004-11-11 Astrazeneca Ab Nitro indazole derivatives
SE0402762D0 (sv) * 2004-11-11 2004-11-11 Astrazeneca Ab Indazole sulphonamide derivatives
WO2007023114A1 (en) * 2005-08-25 2007-03-01 F. Hoffmann-La Roche Ag P38 map kinase inhibitors and methods for using the same
US8119655B2 (en) 2005-10-07 2012-02-21 Takeda Pharmaceutical Company Limited Kinase inhibitors
JP5131990B2 (ja) 2006-01-31 2013-01-30 アレイ バイオファーマ、インコーポレイテッド キナーゼ阻害剤およびその使用方法
EP2223925A1 (en) * 2006-10-09 2010-09-01 Takeda Pharmaceutical Company Limited Kinase inhibitors
JP2010505962A (ja) 2006-10-09 2010-02-25 武田薬品工業株式会社 キナーゼ阻害剤
WO2008063888A2 (en) * 2006-11-22 2008-05-29 Plexxikon, Inc. Compounds modulating c-fms and/or c-kit activity and uses therefor
FR2917735B1 (fr) * 2007-06-21 2009-09-04 Sanofi Aventis Sa Nouveaux indazoles substitutes, leur preparation et leur utilisation en therapeutique
JP5364875B2 (ja) * 2007-07-16 2013-12-11 アッヴィ・インコーポレイテッド タンパク質キナーゼ阻害薬としてのインダゾール類、ベンゾイソオキサゾール類およびベンゾイソチアゾール類
US20220315555A1 (en) 2009-05-26 2022-10-06 Abbvie Inc. Apoptosis inducing agents for the treatment of cancer and immune and autoimmune diseases
PE20120345A1 (es) * 2009-05-26 2012-05-17 Abbvie Bahamas Ltd Derivados de 2-(1h-pirrolo[2,3-b]piridin-5-iloxi)-n-fenilsulfonilbenzamida como inhibidores de proteinas anti-apoptoticas
US8546399B2 (en) 2009-05-26 2013-10-01 Abbvie Inc. Apoptosis inducing agents for the treatment of cancer and immune and autoimmune diseases
US9034875B2 (en) 2009-05-26 2015-05-19 Abbvie Inc. Apoptosis-inducing agents for the treatment of cancer and immune and autoimmune diseases
WO2011050245A1 (en) * 2009-10-23 2011-04-28 Yangbo Feng Bicyclic heteroaryls as kinase inhibitors
CN102247361B (zh) * 2010-05-20 2015-04-29 中国医学科学院药物研究所 5-硝基-1氢-吲唑-3-腈在制备药物中的应用
UA113500C2 (xx) 2010-10-29 2017-02-10 Одержані екструзією розплаву тверді дисперсії, що містять індукуючий апоптоз засіб
KR20180059560A (ko) 2010-10-29 2018-06-04 애브비 인코포레이티드 아폽토시스―유도제를 포함하는 고체 분산체
DK2642999T3 (en) 2010-11-23 2017-01-09 Abbvie Ireland Unlimited Co METHODS OF TREATMENT FOR USING selectivity-VE BCL-2 INHIBITORS
RU2628560C2 (ru) 2010-11-23 2017-08-18 Эббви Инк. Соли и кристаллические формы индуцирующего апоптоз агента
US20140275082A1 (en) 2013-03-14 2014-09-18 Abbvie Inc. Apoptosis-inducing agents for the treatment of cancer and immune and autoimmune diseases
JP6701214B2 (ja) * 2014-11-03 2020-05-27 イオメット ファーマ リミテッド 医薬化合物
GB201511382D0 (en) 2015-06-29 2015-08-12 Imp Innovations Ltd Novel compounds and their use in therapy
JP2020528415A (ja) * 2017-07-21 2020-09-24 カドモン コーポレイション，リミティド ライアビリティ カンパニー Ｒｈｏ関連コイルドコイル含有プロテインキナーゼの阻害剤
WO2019046467A1 (en) 2017-08-29 2019-03-07 Rutgers, The State University Of New Jersey INDAZOLES THERAPEUTIC
WO2023137041A1 (en) * 2022-01-12 2023-07-20 Ifm Due, Inc. Compounds and compositions for treating conditions associated with sting activity
CN114605329B (zh) * 2022-03-28 2024-01-26 河南中医药大学 取代的吲唑甲酰胺或取代的氮杂吲唑甲酰胺类flt3抑制剂及其用途

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS514505Y2 (es) 1971-02-13 1976-02-07
JPH061350B2 (ja) * 1985-07-26 1994-01-05 コニカ株式会社 ハロゲン化銀写真感光材料
ATE249213T1 (de) 1996-02-22 2003-09-15 Tularik Inc Pentafluorobenzensulfonamiden und analoge
DK0939627T3 (da) * 1996-07-19 2003-10-13 Tularik Inc Pentaflourbenzensulfonamider og analoger
GB9718913D0 (en) * 1997-09-05 1997-11-12 Glaxo Group Ltd Substituted oxindole derivatives
US6087368A (en) * 1998-06-08 2000-07-11 Bristol-Myers Squibb Company Quinazolinone inhibitors of cGMP phosphodiesterase
WO2000027627A1 (en) 1998-11-12 2000-05-18 Eli Lilly And Company Aryloxime linkers in the solid-phase synthesis of 3-aminobenzisoxazoles
CO5170498A1 (es) * 1999-05-28 2002-06-27 Abbott Lab Biaril sulfonamidas son utiles como inhibidores de proliferacion celular
YU54202A (sh) 2000-01-18 2006-01-16 Agouron Pharmaceuticals Inc. Jedinjenja indazola, farmaceutske smeše i postupci za stimulisanje i inhibiranje ćelijske proliferacije
KR100423899B1 (ko) * 2000-05-10 2004-03-24 주식회사 엘지생명과학 세포 증식 억제제로 유용한 1,1-디옥소이소티아졸리딘을갖는 인다졸
US6897231B2 (en) * 2000-07-31 2005-05-24 Signal Pharmaceuticals, Inc. Indazole derivatives as JNK inhibitors and compositions and methods related thereto
ATE449763T1 (de) * 2001-04-16 2009-12-15 Eisai R&D Man Co Ltd 1h-indazolverbindungen die jnk hemmen
EP1403255A4 (en) 2001-06-12 2005-04-06 Sumitomo Pharma INHIBITORS OF RHO KINASE
WO2003004488A1 (en) * 2001-07-03 2003-01-16 Chiron Corporation Indazole benzimidazole compounds as tyrosine and serine/threonine kinase inhibitors
WO2003024969A1 (en) 2001-09-14 2003-03-27 Merck & Co., Inc. Tyrosine kinase inhibitors
FR2836915B1 (fr) * 2002-03-11 2008-01-11 Aventis Pharma Sa Derives d'aminoindazoles, procede de preparation et intermediaires de ce procede a titre de medicaments et compositions pharmaceutiques les renfermant
FR2836914B1 (fr) * 2002-03-11 2008-03-14 Aventis Pharma Sa Indazoles substitues, compositions les contenant, procede de fabrication et utilisation

Also Published As

Publication number Publication date
OA12784A (fr) 2006-07-10
PA8566701A1 (es) 2003-12-10
RU2004130280A (ru) 2005-06-27
KR20040091128A (ko) 2004-10-27
US7473701B2 (en) 2009-01-06
UY27712A1 (es) 2003-09-30
CN100369899C (zh) 2008-02-20
EP1487803A1 (fr) 2004-12-22
HRP20040825A2 (en) 2005-06-30
ECSP045286A (es) 2004-10-26
PL372389A1 (en) 2005-07-25
WO2003078402A1 (fr) 2003-09-25
ZA200406730B (en) 2005-08-24
AU2003242808A1 (en) 2003-09-29
FR2836914A1 (fr) 2003-09-12
NO20044261L (no) 2004-11-25
CA2478540A1 (fr) 2003-09-25
MA27176A1 (fr) 2005-01-03
PE20040071A1 (es) 2004-02-13
FR2836914B1 (fr) 2008-03-14
IL163805A0 (en) 2005-12-18
TW200303863A (en) 2003-09-16
TNSN04175A1 (fr) 2007-03-12
AU2003242808B2 (en) 2008-09-18
BR0308339A (pt) 2005-02-01
JP2005533004A (ja) 2005-11-04
IL163805A (en) 2009-08-03
GT200300031A (es) 2006-05-26
AR038914A1 (es) 2005-02-02
CN1642922A (zh) 2005-07-20
JP4643910B2 (ja) 2011-03-02
US20040106667A1 (en) 2004-06-03
US6858638B2 (en) 2005-02-22
US20050059722A1 (en) 2005-03-17
SV2003001493A (es) 2003-07-10
MXPA04008446A (es) 2004-12-06

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