HK1210772A1 - 5-ht3 receptor antagonists 5-ht3 - Google Patents

5-ht3 receptor antagonists 5-ht3

Info

Publication number
HK1210772A1
HK1210772A1 HK15111424.6A HK15111424A HK1210772A1 HK 1210772 A1 HK1210772 A1 HK 1210772A1 HK 15111424 A HK15111424 A HK 15111424A HK 1210772 A1 HK1210772 A1 HK 1210772A1
Authority
HK
Hong Kong
Prior art keywords
receptor antagonists
antagonists
receptor
Prior art date
Application number
HK15111424.6A
Other languages
English (en)
Chinese (zh)
Inventor
Stephen Hitchcock
Holger Monenschein
Holly Reichard
Huikai Sun
Shota Kikuchi
Todd Macklin
Maria Hopkins
Original Assignee
Takeda Pharmaceutical
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=48877569&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=HK1210772(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Takeda Pharmaceutical filed Critical Takeda Pharmaceutical
Publication of HK1210772A1 publication Critical patent/HK1210772A1/xx

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    • C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D498/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D498/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D498/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D498/08—Bridged systems
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    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
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    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
    • A61K31/5375—1,4-Oxazines, e.g. morpholine
    • A61K31/5386—1,4-Oxazines, e.g. morpholine spiro-condensed or forming part of bridged ring systems
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    • C07D451/04—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof with hetero atoms directly attached in position 3 of the 8-azabicyclo [3.2.1] octane or in position 7 of the 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring system
    • C07D451/06—Oxygen atoms
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    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
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    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
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  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Epidemiology (AREA)
  • Pain & Pain Management (AREA)
  • Psychiatry (AREA)
  • Toxicology (AREA)
  • Hospice & Palliative Care (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Immunology (AREA)
  • Psychology (AREA)
  • Rheumatology (AREA)
  • Nutrition Science (AREA)
  • Addiction (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Vascular Medicine (AREA)
  • Cardiology (AREA)
  • Child & Adolescent Psychology (AREA)
  • Otolaryngology (AREA)
  • Obesity (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Urology & Nephrology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
HK15111424.6A 2012-07-17 2015-11-19 5-ht3 receptor antagonists 5-ht3 HK1210772A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201261672709P 2012-07-17 2012-07-17
US201261708521P 2012-10-01 2012-10-01
PCT/US2013/050746 WO2014014951A1 (en) 2012-07-17 2013-07-16 5-ht3 receptor antagonists

Publications (1)

Publication Number Publication Date
HK1210772A1 true HK1210772A1 (en) 2016-05-06

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ID=48877569

Family Applications (2)

Application Number Title Priority Date Filing Date
HK15111424.6A HK1210772A1 (en) 2012-07-17 2015-11-19 5-ht3 receptor antagonists 5-ht3
HK18111657.1A HK1252279A1 (zh) 2012-07-17 2018-09-11 5- ht3受體拮抗劑

Family Applications After (1)

Application Number Title Priority Date Filing Date
HK18111657.1A HK1252279A1 (zh) 2012-07-17 2018-09-11 5- ht3受體拮抗劑

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US (8) US9012447B2 (el)
EP (3) EP3312169B1 (el)
JP (5) JP5816400B2 (el)
KR (1) KR102148969B1 (el)
CN (2) CN106478662B (el)
AP (1) AP2015008240A0 (el)
AR (1) AR091781A1 (el)
AU (1) AU2013290375B2 (el)
BR (1) BR112015001028B1 (el)
CA (1) CA2879115C (el)
CL (1) CL2015000121A1 (el)
CO (1) CO7280468A2 (el)
CR (1) CR20150057A (el)
CY (1) CY1120881T1 (el)
DK (2) DK3312169T3 (el)
DO (1) DOP2015000009A (el)
EA (1) EA025986B1 (el)
EC (1) ECSP15004780A (el)
ES (2) ES2659758T3 (el)
GE (1) GEP201606526B (el)
HK (2) HK1210772A1 (el)
HR (1) HRP20180523T1 (el)
HU (2) HUE038757T2 (el)
IL (1) IL236702B (el)
IN (1) IN2015DN00957A (el)
JO (1) JOP20130213B1 (el)
LT (1) LT2875011T (el)
ME (1) ME03005B (el)
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MY (1) MY182432A (el)
NZ (1) NZ704814A (el)
PE (1) PE20150671A1 (el)
PH (1) PH12015500085B1 (el)
PL (2) PL3312169T3 (el)
PT (2) PT3312169T (el)
RS (1) RS57096B1 (el)
SG (1) SG11201500302UA (el)
SI (1) SI2875011T1 (el)
TN (1) TN2015000018A1 (el)
TW (1) TWI602821B (el)
UY (1) UY34912A (el)
WO (2) WO2014014951A1 (el)
ZA (1) ZA201500781B (el)

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WO2016053947A1 (en) * 2014-09-29 2016-04-07 Takeda Pharmaceutical Company Limited Crystalline form of 1-(1-methyl-1h-pyrazol-4-yl)-n-((1r,5s,7s)-9-methyl-3-oxa-9-azabicyclo[3.3.1]nonan-7-yl)-1h-indole-3-carboxamide
JP6612874B2 (ja) 2014-12-16 2019-11-27 アクソファント サイエンシーズ ゲーエムベーハー α７−ニコチン性アセチルコリン受容体のアゴニストとしてのジェミナル置換キヌクリジンアミド化合物
MX2017016231A (es) 2015-06-10 2018-11-29 Axovant Sciences Gmbh Compuestos de aminobencisoxazol como agonistas de receptores a7-nicotínicos de acetilcolina.
US10428062B2 (en) 2015-08-12 2019-10-01 Axovant Sciences Gmbh Geminal substituted aminobenzisoxazole compounds as agonists of α7-nicotinic acetylcholine receptors
CN110662537A (zh) * 2017-03-27 2020-01-07 才思治疗公司 用于治疗共核蛋白病的组合物和方法
US20200375957A1 (en) * 2017-04-24 2020-12-03 Chase Therapeutics Corporation Compositions and method for treating depression
EP3645120A4 (en) 2017-06-30 2021-03-24 Chase Pharmaceuticals Corporation NK-1 ANTAGONIST COMPOSITIONS AND METHODS OF USE IN THE TREATMENT OF DEPRESSION
WO2019180176A1 (en) 2018-03-21 2019-09-26 Spherium Biomed, S.L. Composition for the treatment of schizophrenia and/or psychosis
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