DE3777805D1 - Arzneimittel zur behandlung oder vorbeugung des entzugssyndromes. - Google Patents
Arzneimittel zur behandlung oder vorbeugung des entzugssyndromes.Info
- Publication number
- DE3777805D1 DE3777805D1 DE8787310290T DE3777805T DE3777805D1 DE 3777805 D1 DE3777805 D1 DE 3777805D1 DE 8787310290 T DE8787310290 T DE 8787310290T DE 3777805 T DE3777805 T DE 3777805T DE 3777805 D1 DE3777805 D1 DE 3777805D1
- Authority
- DE
- Germany
- Prior art keywords
- medicines
- treating
- preventing
- withdrawal syndrome
- withdrawal
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/46—8-Azabicyclo [3.2.1] octane; Derivatives thereof, e.g. atropine, cocaine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Epidemiology (AREA)
- Emergency Medicine (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (5)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB868627909A GB8627909D0 (en) | 1986-11-21 | 1986-11-21 | Medicaments |
GB868627881A GB8627881D0 (en) | 1986-11-21 | 1986-11-21 | Medicaments |
GB868627883A GB8627883D0 (en) | 1986-11-21 | 1986-11-21 | Medicaments |
GB868630083A GB8630083D0 (en) | 1986-12-17 | 1986-12-17 | Medicaments |
GB878707177A GB8707177D0 (en) | 1987-03-25 | 1987-03-25 | Medicaments |
Publications (1)
Publication Number | Publication Date |
---|---|
DE3777805D1 true DE3777805D1 (de) | 1992-04-30 |
Family
ID=27516687
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE8787310290T Expired - Lifetime DE3777805D1 (de) | 1986-11-21 | 1987-11-20 | Arzneimittel zur behandlung oder vorbeugung des entzugssyndromes. |
Country Status (7)
Country | Link |
---|---|
US (2) | US4948803A (de) |
EP (1) | EP0279114B2 (de) |
JP (1) | JP2765845B2 (de) |
DE (1) | DE3777805D1 (de) |
ES (1) | ES2036587T5 (de) |
GR (1) | GR3004150T3 (de) |
WO (1) | WO1988003801A1 (de) |
Families Citing this family (24)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE3822792C2 (de) * | 1987-07-11 | 1997-11-27 | Sandoz Ag | Neue Verwendung von 5HT¶3¶-Antagonisten |
GB2240476B (en) * | 1987-07-11 | 1992-03-18 | Sandoz Ltd | 5 ht-3 antagonists for the prevention or reduction of dependence |
GB8820650D0 (en) * | 1988-09-01 | 1988-10-05 | Glaxo Group Ltd | Medicaments |
US4999382A (en) * | 1988-10-26 | 1991-03-12 | Massachusetts Institute Of Technology | Compositions for treating tobacco withdrawal symptoms and methods for their use |
ES2061024T3 (es) | 1989-04-21 | 1994-12-01 | Sandoz Ag | Uso terapeutico de antagonistas de receptores de 5-ht3. |
IE913621A1 (en) * | 1990-10-17 | 1992-04-22 | Beecham Group Plc | Novel treatment |
US5189041A (en) * | 1990-11-16 | 1993-02-23 | Syntex (U.S.A.) Inc. | Tricyclic 5-ht3 receptor antagonists |
JP2699794B2 (ja) * | 1992-03-12 | 1998-01-19 | 三菱化学株式会社 | チエノ〔3,2−b〕ピリジン誘導体 |
GB9312315D0 (en) * | 1993-06-15 | 1993-07-28 | Poston Robin | Leukocyte adhesion assay |
US5824684A (en) * | 1997-02-21 | 1998-10-20 | Synapse Pharmaceuticals International, Inc. | Method for treating drug and alcohol addiction |
US7629355B2 (en) * | 2003-10-14 | 2009-12-08 | Lawson John A | Treatment of chemical dependency with substantially nonaddicting normorphine and norcodeine derivatives |
TW200533348A (en) * | 2004-02-18 | 2005-10-16 | Theravance Inc | Indazole-carboxamide compounds as 5-ht4 receptor agonists |
US8309575B2 (en) | 2004-04-07 | 2012-11-13 | Theravance, Inc. | Quinolinone-carboxamide compounds as 5-HT4 receptor agonists |
US7728006B2 (en) * | 2004-04-07 | 2010-06-01 | Theravance, Inc. | Quinolinone-carboxamide compounds as 5-HT4 receptor agonists |
TWI351282B (en) | 2004-04-07 | 2011-11-01 | Theravance Inc | Quinolinone-carboxamide compounds as 5-ht4 recepto |
EP1807422B1 (de) * | 2004-11-05 | 2009-09-02 | Theravance, Inc. | 5-HT4-Rezeptoragonistenverbindungen |
WO2006052889A2 (en) * | 2004-11-05 | 2006-05-18 | Theravance, Inc. | Quinolinone-carboxamide compounds |
JP5030194B2 (ja) | 2004-11-25 | 2012-09-19 | 国立大学法人九州大学 | 薬物依存症治療剤 |
US7419989B2 (en) * | 2004-12-22 | 2008-09-02 | Theravance, Inc. | Indazole-carboxamide compounds |
CN101163701A (zh) * | 2005-03-02 | 2008-04-16 | 施万制药 | 作为5-ht4受体激动剂的喹啉酮化合物 |
US9226918B2 (en) | 2008-12-04 | 2016-01-05 | The Board Of Trustees Of The Leland Stanford Junior University | Methods and compositions for treating or preventing narcotic withdrawal symptoms |
US20110288115A1 (en) | 2010-05-24 | 2011-11-24 | Avmedis Llc | Treatment of vagally-mediated spectrum disorders |
JOP20130213B1 (ar) | 2012-07-17 | 2021-08-17 | Takeda Pharmaceuticals Co | معارضات لمستقبلht3-5 |
WO2016053947A1 (en) | 2014-09-29 | 2016-04-07 | Takeda Pharmaceutical Company Limited | Crystalline form of 1-(1-methyl-1h-pyrazol-4-yl)-n-((1r,5s,7s)-9-methyl-3-oxa-9-azabicyclo[3.3.1]nonan-7-yl)-1h-indole-3-carboxamide |
Family Cites Families (14)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2531083B1 (fr) * | 1982-06-29 | 1986-11-28 | Sandoz Sa | Nouveaux derives de la piperidine, leur preparation et leur utilisation comme medicaments |
US4499096A (en) * | 1983-11-18 | 1985-02-12 | Lotsof Howard S | Rapid method for interrupting the narcotic addiction syndrome |
HU193592B (en) * | 1984-01-25 | 1987-11-30 | Glaxo Group Ltd | Process for producing tetrahydro-carbazolone derivatives |
ATE86110T1 (de) * | 1984-12-20 | 1993-03-15 | Sandoz Ag | Behandlung von gastrointestinalkrankheiten durch anwendung von 5-ht3-antagonisten. |
EP0405617A3 (en) * | 1985-03-14 | 1992-11-25 | Beecham Group P.L.C. | Medicaments for the treatment of anxiety |
DE3687080T2 (de) * | 1985-04-27 | 1993-03-25 | Beecham Group Plc | Azabicyclononyl-indazol-carboxamid mit 5-ht-antagonistischer wirkung. |
GB8518658D0 (en) * | 1985-07-24 | 1985-08-29 | Glaxo Group Ltd | Medicaments |
US4808581A (en) * | 1986-03-17 | 1989-02-28 | Glaxo Group Limited | Imidazolyl- indolylpropanones as 5-HT3 receptor antagonists |
HU895334D0 (en) * | 1986-07-30 | 1990-01-28 | Sandoz Ag | Process for the preparation of nasal pharmaceutical compositions |
GB8627909D0 (en) * | 1986-11-21 | 1986-12-31 | Glaxo Group Ltd | Medicaments |
DE3780276T2 (de) * | 1986-12-16 | 1993-02-25 | Robins Co Inc A H | Angstloesende n-(1-azabicyclo(2.2.2)oct-3-yl)benzamide und -thiobenzamide. |
ES2074981T3 (es) * | 1986-12-17 | 1995-10-01 | Glaxo Group Ltd | Uso de derivados heterociclicos en el tratamiento de trastornos cognoscitivos. |
US4973594A (en) * | 1986-12-17 | 1990-11-27 | Glaxo Group Limited | Medicaments |
DE3822792C2 (de) * | 1987-07-11 | 1997-11-27 | Sandoz Ag | Neue Verwendung von 5HT¶3¶-Antagonisten |
-
1987
- 1987-11-20 WO PCT/GB1987/000826 patent/WO1988003801A1/en unknown
- 1987-11-20 DE DE8787310290T patent/DE3777805D1/de not_active Expired - Lifetime
- 1987-11-20 EP EP87310290A patent/EP0279114B2/de not_active Expired - Lifetime
- 1987-11-20 JP JP62506822A patent/JP2765845B2/ja not_active Expired - Lifetime
- 1987-11-20 ES ES87310290T patent/ES2036587T5/es not_active Expired - Lifetime
- 1987-11-20 US US07/246,550 patent/US4948803A/en not_active Expired - Lifetime
-
1992
- 1992-03-26 GR GR920400437T patent/GR3004150T3/el unknown
-
1993
- 1993-01-07 US US08/001,665 patent/US5298510A/en not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
US4948803A (en) | 1990-08-14 |
ES2036587T3 (es) | 1995-04-01 |
GR3004150T3 (en) | 1993-03-31 |
EP0279114B1 (de) | 1992-03-25 |
ES2036587T5 (es) | 1995-10-16 |
EP0279114A1 (de) | 1988-08-24 |
JPH01502186A (ja) | 1989-08-03 |
JP2765845B2 (ja) | 1998-06-18 |
WO1988003801A1 (en) | 1988-06-02 |
US5298510A (en) | 1994-03-29 |
EP0279114B2 (de) | 1995-08-23 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8363 | Opposition against the patent | ||
8366 | Restricted maintained after opposition proceedings |