HK1209581A1 - Production of long chain polyunsaturated fatty acids in plant cells - Google Patents

Production of long chain polyunsaturated fatty acids in plant cells

Info

Publication number
HK1209581A1
HK1209581A1 HK15110384.6A HK15110384A HK1209581A1 HK 1209581 A1 HK1209581 A1 HK 1209581A1 HK 15110384 A HK15110384 A HK 15110384A HK 1209581 A1 HK1209581 A1 HK 1209581A1
Authority
HK
Hong Kong
Prior art keywords
production
fatty acids
long chain
plant cells
polyunsaturated fatty
Prior art date
Application number
HK15110384.6A
Other languages
English (en)
Chinese (zh)
Inventor
James Robertson Petrie
Surinder Pal Singh
Feyter Robert Charles De
Original Assignee
Commw Scient Ind Res Org
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=49756497&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=HK1209581(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Commw Scient Ind Res Org filed Critical Commw Scient Ind Res Org
Publication of HK1209581A1 publication Critical patent/HK1209581A1/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
    • C11B—PRODUCING, e.g. BY PRESSING RAW MATERIALS OR BY EXTRACTION FROM WASTE MATERIALS, REFINING OR PRESERVING FATS, FATTY SUBSTANCES, e.g. LANOLIN, FATTY OILS OR WAXES; ESSENTIAL OILS; PERFUMES
    • C11B1/00—Production of fats or fatty oils from raw materials
    • C—CHEMISTRY; METALLURGY
    • C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
    • C11B—PRODUCING, e.g. BY PRESSING RAW MATERIALS OR BY EXTRACTION FROM WASTE MATERIALS, REFINING OR PRESERVING FATS, FATTY SUBSTANCES, e.g. LANOLIN, FATTY OILS OR WAXES; ESSENTIAL OILS; PERFUMES
    • C11B1/00—Production of fats or fatty oils from raw materials
    • C11B1/10—Production of fats or fatty oils from raw materials by extracting
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/22—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
    • A61K31/23—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin of acids having a carboxyl group bound to a chain of seven or more carbon atoms
    • A61K31/232—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin of acids having a carboxyl group bound to a chain of seven or more carbon atoms having three or more double bonds, e.g. etretinate
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01H—NEW PLANTS OR NON-TRANSGENIC PROCESSES FOR OBTAINING THEM; PLANT REPRODUCTION BY TISSUE CULTURE TECHNIQUES
    • A01H1/00—Processes for modifying genotypes ; Plants characterised by associated natural traits
    • A01H1/10—Processes for modifying non-agronomic quality output traits, e.g. for industrial processing; Value added, non-agronomic traits
    • A01H1/101—Processes for modifying non-agronomic quality output traits, e.g. for industrial processing; Value added, non-agronomic traits involving biosynthetic or metabolic pathways, i.e. metabolic engineering, e.g. nicotine or caffeine
    • A01H1/104—Processes for modifying non-agronomic quality output traits, e.g. for industrial processing; Value added, non-agronomic traits involving biosynthetic or metabolic pathways, i.e. metabolic engineering, e.g. nicotine or caffeine involving modified lipid metabolism, e.g. seed oil composition
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01H—NEW PLANTS OR NON-TRANSGENIC PROCESSES FOR OBTAINING THEM; PLANT REPRODUCTION BY TISSUE CULTURE TECHNIQUES
    • A01H5/00—Angiosperms, i.e. flowering plants, characterised by their plant parts; Angiosperms characterised otherwise than by their botanic taxonomy
    • A01H5/10—Seeds
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01H—NEW PLANTS OR NON-TRANSGENIC PROCESSES FOR OBTAINING THEM; PLANT REPRODUCTION BY TISSUE CULTURE TECHNIQUES
    • A01H6/00—Angiosperms, i.e. flowering plants, characterised by their botanic taxonomy
    • A01H6/20—Brassicaceae, e.g. canola, broccoli or rucola
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/31—Brassicaceae or Cruciferae (Mustard family), e.g. broccoli, cabbage or kohlrabi
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/12—Drugs for disorders of the urinary system of the kidneys
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/06—Antipsoriatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/08—Antiseborrheics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/02—Nutrients, e.g. vitamins, minerals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/18—Antivirals for RNA viruses for HIV
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/06—Antiarrhythmics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C57/00—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms
    • C07C57/02—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms with only carbon-to-carbon double bonds as unsaturation
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C57/00—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms
    • C07C57/02—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms with only carbon-to-carbon double bonds as unsaturation
    • C07C57/03—Monocarboxylic acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C67/00—Preparation of carboxylic acid esters
    • C07C67/02—Preparation of carboxylic acid esters by interreacting ester groups, i.e. transesterification
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/415—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from plants
    • C—CHEMISTRY; METALLURGY
    • C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
    • C11C—FATTY ACIDS FROM FATS, OILS OR WAXES; CANDLES; FATS, OILS OR FATTY ACIDS BY CHEMICAL MODIFICATION OF FATS, OILS, OR FATTY ACIDS OBTAINED THEREFROM
    • C11C1/00—Preparation of fatty acids from fats, fatty oils, or waxes; Refining the fatty acids
    • C11C1/002—Sources of fatty acids, e.g. natural glycerides, characterised by the nature, the quantities or the distribution of said acids
    • C—CHEMISTRY; METALLURGY
    • C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
    • C11C—FATTY ACIDS FROM FATS, OILS OR WAXES; CANDLES; FATS, OILS OR FATTY ACIDS BY CHEMICAL MODIFICATION OF FATS, OILS, OR FATTY ACIDS OBTAINED THEREFROM
    • C11C3/00—Fats, oils, or fatty acids by chemical modification of fats, oils, or fatty acids obtained therefrom
    • C—CHEMISTRY; METALLURGY
    • C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
    • C11C—FATTY ACIDS FROM FATS, OILS OR WAXES; CANDLES; FATS, OILS OR FATTY ACIDS BY CHEMICAL MODIFICATION OF FATS, OILS, OR FATTY ACIDS OBTAINED THEREFROM
    • C11C3/00—Fats, oils, or fatty acids by chemical modification of fats, oils, or fatty acids obtained therefrom
    • C11C3/003—Fats, oils, or fatty acids by chemical modification of fats, oils, or fatty acids obtained therefrom by esterification of fatty acids with alcohols
    • C—CHEMISTRY; METALLURGY
    • C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
    • C11C—FATTY ACIDS FROM FATS, OILS OR WAXES; CANDLES; FATS, OILS OR FATTY ACIDS BY CHEMICAL MODIFICATION OF FATS, OILS, OR FATTY ACIDS OBTAINED THEREFROM
    • C11C3/00—Fats, oils, or fatty acids by chemical modification of fats, oils, or fatty acids obtained therefrom
    • C11C3/04—Fats, oils, or fatty acids by chemical modification of fats, oils, or fatty acids obtained therefrom by esterification of fats or fatty oils
    • C11C3/06—Fats, oils, or fatty acids by chemical modification of fats, oils, or fatty acids obtained therefrom by esterification of fats or fatty oils with glycerol
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/52—Genes encoding for enzymes or proenzymes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
    • C12N15/8201—Methods for introducing genetic material into plant cells, e.g. DNA, RNA, stable or transient incorporation, tissue culture methods adapted for transformation
    • C12N15/8202—Methods for introducing genetic material into plant cells, e.g. DNA, RNA, stable or transient incorporation, tissue culture methods adapted for transformation by biological means, e.g. cell mediated or natural vector
    • C12N15/8205—Agrobacterium mediated transformation
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
    • C12N15/8216—Methods for controlling, regulating or enhancing expression of transgenes in plant cells
    • C12N15/8222—Developmentally regulated expression systems, tissue, organ specific, temporal or spatial regulation
    • C12N15/823—Reproductive tissue-specific promoters
    • C12N15/8234—Seed-specific, e.g. embryo, endosperm
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
    • C12N15/8241—Phenotypically and genetically modified plants via recombinant DNA technology
    • C12N15/8242—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits
    • C12N15/8243—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits involving biosynthetic or metabolic pathways, i.e. metabolic engineering, e.g. nicotine, caffeine
    • C12N15/8247—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits involving biosynthetic or metabolic pathways, i.e. metabolic engineering, e.g. nicotine, caffeine involving modified lipid metabolism, e.g. seed oil composition
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
    • C12N9/1025—Acyltransferases (2.3)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y203/00—Acyltransferases (2.3)
    • C12Y203/01—Acyltransferases (2.3) transferring groups other than amino-acyl groups (2.3.1)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y203/00—Acyltransferases (2.3)
    • C12Y203/01—Acyltransferases (2.3) transferring groups other than amino-acyl groups (2.3.1)
    • C12Y203/01075—Long-chain-alcohol O-fatty-acyltransferase (2.3.1.75)
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23K—FODDER
    • A23K20/00—Accessory food factors for animal feeding-stuffs
    • A23K20/10—Organic substances
    • A23K20/158—Fatty acids; Fats; Products containing oils or fats
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/115—Fatty acids or derivatives thereof; Fats or oils
    • A23L33/12—Fatty acids or derivatives thereof
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
    • A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30—Extraction of the material
    • A61K2236/35—Extraction with lipophilic solvents, e.g. Hexane or petrol ether
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/22—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
    • A61K31/23—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin of acids having a carboxyl group bound to a chain of seven or more carbon atoms
    • A61K31/231—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin of acids having a carboxyl group bound to a chain of seven or more carbon atoms having one or two double bonds

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Zoology (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • General Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Biophysics (AREA)
  • Botany (AREA)
  • Plant Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Diabetes (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Nutrition Science (AREA)
  • Cell Biology (AREA)
  • Developmental Biology & Embryology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Environmental Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Cardiology (AREA)
HK15110384.6A 2012-06-15 2015-10-22 Production of long chain polyunsaturated fatty acids in plant cells HK1209581A1 (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201261660392P 2012-06-15 2012-06-15
US201261663344P 2012-06-22 2012-06-22
US201261697676P 2012-09-06 2012-09-06
US201361782680P 2013-03-14 2013-03-14
PCT/AU2013/000639 WO2013185184A2 (en) 2012-06-15 2013-06-14 Production of long chain polyunsaturated fatty acids in plant cells

Publications (1)

Publication Number Publication Date
HK1209581A1 true HK1209581A1 (en) 2016-04-08

Family

ID=49756497

Family Applications (2)

Application Number Title Priority Date Filing Date
HK15110384.6A HK1209581A1 (en) 2012-06-15 2015-10-22 Production of long chain polyunsaturated fatty acids in plant cells
HK18108838.9A HK1248989A1 (zh) 2012-06-15 2018-07-09 在植物細胞中產生長鏈多不飽和脂肪酸

Family Applications After (1)

Application Number Title Priority Date Filing Date
HK18108838.9A HK1248989A1 (zh) 2012-06-15 2018-07-09 在植物細胞中產生長鏈多不飽和脂肪酸

Country Status (26)

Country Link
US (16) US8946460B2 (pt)
EP (2) EP3266316A1 (pt)
JP (3) JP6242882B2 (pt)
KR (2) KR102197208B1 (pt)
CN (2) CN109294730B (pt)
AU (4) AU2013273934B2 (pt)
BR (2) BR122019026149A8 (pt)
CA (2) CA2876519C (pt)
CL (2) CL2014003402A1 (pt)
DK (1) DK2861059T3 (pt)
EA (1) EA036786B1 (pt)
ES (1) ES2636487T3 (pt)
HK (2) HK1209581A1 (pt)
HU (1) HUE033766T2 (pt)
IL (1) IL236288A (pt)
MX (1) MX349678B (pt)
MY (1) MY187101A (pt)
NZ (1) NZ631702A (pt)
PE (2) PE20150769A1 (pt)
PH (1) PH12014502795A1 (pt)
PL (1) PL2861059T3 (pt)
PT (1) PT2861059T (pt)
SG (2) SG11201408362SA (pt)
UA (2) UA117223C2 (pt)
WO (1) WO2013185184A2 (pt)
ZA (1) ZA201500015B (pt)

Families Citing this family (48)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA3056163C (en) 2004-04-22 2021-04-06 Commonwealth Scientific And Industrial Research Organisation Synthesis of long-chain polyunsaturated fatty acids by recombinant cells
US7807849B2 (en) 2004-04-22 2010-10-05 Commonwealth Scientific And Industrial Research Organisation Synthesis of long-chain polyunsaturated fatty acids by recombinant cells
CN101578363A (zh) 2006-08-29 2009-11-11 联邦科学技术研究组织 脂肪酸的合成
EP2283137A4 (en) * 2008-04-25 2011-12-14 Commw Scient Ind Res Org RECOMBINANT CELLS AND METHOD FOR THE HYDROXYLATION OF FATTY ACIDS
ES2644883T3 (es) 2008-11-18 2017-11-30 Commonwealth Scientific And Industrial Research Organisation Enzimas y métodos para producir ácidos grasos omega-3
AU2010272536B2 (en) 2009-07-17 2016-09-08 Basf Plant Science Company Gmbh Novel fatty acid desaturases and elongases and uses thereof
SG11201408362SA (en) 2012-06-15 2015-01-29 Commw Scient Ind Res Org Production of long chain polyunsaturated fatty acids in plant cells
DK2935601T3 (en) * 2012-12-21 2018-06-18 Du Pont RECOMBINANT MICROBELL CELLS PRODUCING AT LEAST 28% EICOSAPENTAIC ACID AS DRY WEIGHT
CA2933909A1 (en) 2013-12-18 2015-06-25 Grains Research And Development Corporation Lipid comprising long chain polyunsaturated fatty acids
US11718577B2 (en) * 2013-12-18 2023-08-08 Commonwealth Scientific And Industrial Research Organisation Lipid compositions comprising triacylglycerol with long-chain polyunsaturated fatty acids
US9752165B2 (en) * 2014-02-10 2017-09-05 Cellulosic Ethanol Technologies, Llc Processes and systems for recovering oil from fermentation products
MY188557A (en) * 2014-06-27 2021-12-22 Commw Scient Ind Res Org Lipid comprising docosapentaenoic acid
EA037184B1 (ru) * 2014-06-27 2021-02-16 Коммонвелт Сайнтифик Энд Индастриэл Рисерч Организэйшн Липид, содержащий докозапентаеновую кислоту
CA2953008C (en) 2014-06-27 2024-03-19 Nuseed Pty Ltd Lipid comprising docosapentaenoic acid
BR112016030971B1 (pt) 2014-07-07 2022-09-27 Commonwealth Scientific And Industrial Research Organisation Processo para produzir um produto de óleo e processo para produzir um produto de óleo a partir do óleo da planta
WO2016075313A1 (en) 2014-11-14 2016-05-19 Basf Plant Science Company Gmbh Materials and methods for increasing the tocopherol content in seed oil
CN105053569B (zh) * 2015-08-27 2018-12-18 广州市优百特饲料科技有限公司 一种功能性脂肪饲料添加剂及其制备方法
CN105029096B (zh) * 2015-08-27 2018-08-17 广州市优百特饲料科技有限公司 一种幼禽脂肪粉及其制备方法
AR109245A1 (es) * 2016-05-12 2018-11-14 Basf Plant Science Co Gmbh Métodos para optimizar la producción de metabolitos en plantas genéticamente modificadas y para procesar estas plantas
EP3472281A4 (en) * 2016-06-16 2020-02-19 Nuseed Pty Ltd ELITE EVENT RAPS NS-B50027-4
BR112018076323A8 (pt) 2016-06-16 2022-11-08 Nuseed Pty Ltd Segregante da linhagem de canola endogâmica ns-b50027-4, planta de canola ou parte desta, método para obtenção de uma linhagem de canola endogâmica, método de produção de ácido eicosapentaenóico (epa), ácido docosapentaenóico (dpa), ou ácido docosahexaenóico (dha) na semente de uma planta, semente da planta, método de produção de óleo de canola contendo ácido docosahexaenóico (dha), método de aumento da produção de ácidos graxos poli-insaturados de cadeia longa (lc-pufa), e linhagem de canola endogâmica
CN110462043A (zh) 2016-09-02 2019-11-15 联邦科学技术研究组织 具有修饰的性状的植物
EP3367716B1 (en) 2017-02-22 2021-04-21 CTIA - The Wireless Association Mobile message source authentication
CN107114369B (zh) * 2017-03-24 2020-01-21 浙江大学 植物磺肽素-α在提高植物灰霉病抗性中的应用
KR101976468B1 (ko) * 2017-11-30 2019-05-10 주식회사이맥솔루션 요소수 점적 결정법을 이용한 고산가 유지 폐자원 활용 고순도 불포화 지방산 메틸 에스테르의 제조방법
US11913006B2 (en) 2018-03-16 2024-02-27 Nuseed Global Innovation Ltd. Plants producing modified levels of medium chain fatty acids
CN108315394A (zh) * 2018-04-23 2018-07-24 沈阳师范大学 甜高粱蔗糖合成酶基因的表达检测方法及扩增引物
EP3784044A1 (en) * 2018-04-25 2021-03-03 Nuseed Pty Ltd Dha enriched polyunsaturated fatty acid compositions
EP3560342B1 (en) 2018-04-25 2020-06-03 Nuseed Pty Ltd Dha enriched polyunsaturated fatty acid compositions
CN108452156A (zh) * 2018-05-02 2018-08-28 郭书安 一种治疗冠心病的口服液
EP3586640A1 (en) 2018-06-21 2020-01-01 Nuseed Pty Ltd Dha enriched polyunsaturated fatty acid compositions
EP3586641A1 (en) 2018-06-21 2020-01-01 Nuseed Pty Ltd Dha enriched polyunsaturated fatty acid compositions
EP3586642A1 (en) 2018-06-21 2020-01-01 Nuseed Pty Ltd Ala enriched polyunsaturated fatty acid compositions
EP3586643A1 (en) 2018-06-21 2020-01-01 Nuseed Pty Ltd Dha enriched polyunsaturated fatty acid compositions
WO2020055763A1 (en) * 2018-09-11 2020-03-19 Nuseed Pty Ltd Methods of identifying dha canola ns-b50027-4
KR102216753B1 (ko) * 2018-11-27 2021-02-17 주식회사이맥솔루션 팜유 또는 동물성 폐유지를 이용한 고순도 불포화 지방산 메틸 에스테르 제조방법
CN109796328B (zh) * 2019-03-14 2022-03-25 浙江工业大学 一种高纯度香榧籽油金松酸的分离方法
AU2020336357A1 (en) * 2019-08-26 2022-04-21 Nuseed Nutritional Australia Pty Ltd. Brassica juncea line NUBJ1207
CN110476816B (zh) * 2019-09-29 2022-10-14 西南大学 一种快速获得葡萄桐幼苗的方法
AU2020370081A1 (en) 2019-10-25 2022-06-02 Nuseed Pty Ltd. Enriched polyunsaturated fatty acid compositions
CN111235170A (zh) * 2020-01-17 2020-06-05 华中农业大学 qMYR2基因在调节或筛选稻米中油脂组分含量的应用
US20210254092A1 (en) * 2020-02-07 2021-08-19 Board Of Regents Of The University Of Nebraska Methods of Producing Insect Pheromones
US20240100168A1 (en) * 2020-04-17 2024-03-28 Wake Forest University Lipid compositions and methods of preparation thereof
JP7162352B2 (ja) * 2020-05-01 2022-10-28 株式会社東洋発酵 外用組成物
WO2021226242A1 (en) 2020-05-05 2021-11-11 Nuseed Pty Ltd Aquafeed for improved fish health
WO2022129619A1 (en) * 2020-12-18 2022-06-23 Rothamsted Research Limited Increasing the accumulation of epa and dha in recombinant camelina
CN112816635B (zh) * 2020-12-31 2023-08-18 绿城农科检测技术有限公司 一种黑木耳中测定脂肪酸的方法
CN114208843A (zh) * 2021-12-03 2022-03-22 浙江万里学院 一种植物生长调节剂、提高香蕉果实耐冷性的处理方法及验证方法

Family Cites Families (285)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3484155A (en) 1966-02-07 1969-12-16 Donald L Praeger Head mounted electric squint light
FR1564863A (pt) 1968-03-12 1969-04-25
US4399216A (en) 1980-02-25 1983-08-16 The Trustees Of Columbia University Processes for inserting DNA into eucaryotic cells and for producing proteinaceous materials
EP0131623B2 (en) 1983-01-17 1999-07-28 Monsanto Company Chimeric genes suitable for expression in plant cells
US5504200A (en) 1983-04-15 1996-04-02 Mycogen Plant Science, Inc. Plant gene expression
EP0154204B1 (en) 1984-03-06 1994-01-12 Mgi Pharma, Inc. Herbicide resistance in plants
US5420034A (en) 1986-07-31 1995-05-30 Calgene, Inc. Seed-specific transcriptional regulation
CA1338902C (en) 1986-02-27 1997-02-11 Howard M. Goodman Plant cells resistant to herbicidal glutamine synthetase inhibitors
MA20977A1 (fr) 1986-05-19 1987-12-31 Ciba Geigy Ag Plantes tolerant les herbicides contenant le gene de gluthathione S-Transferase
US5188958A (en) 1986-05-29 1993-02-23 Calgene, Inc. Transformation and foreign gene expression in brassica species
US5177010A (en) 1986-06-30 1993-01-05 University Of Toledo Process for transforming corn and the products thereof
SE455438B (sv) 1986-11-24 1988-07-11 Aga Ab Sett att senka en brennares flamtemperatur samt brennare med munstycken for oxygen resp brensle
US5004863B2 (en) 1986-12-03 2000-10-17 Agracetus Genetic engineering of cotton plants and lines
CN87100603A (zh) 1987-01-21 1988-08-10 昂科公司 抗黑素瘤疫苗
US5416011A (en) 1988-07-22 1995-05-16 Monsanto Company Method for soybean transformation and regeneration
US5932479A (en) 1988-09-26 1999-08-03 Auburn University Genetic engineering of plant chloroplasts
BR9007588A (pt) 1989-08-09 1992-06-30 Dekalb Plant Genetics Processo e composicoes para a producao de plantas monocotiledoneas ferteis,transformadas de maneira estavel,e suas celulas
CA2058756A1 (en) 1990-03-16 1991-09-17 Vic. C. Knauf Sequences preferentially expressed in early seed development and methods related thereto
US5451513A (en) 1990-05-01 1995-09-19 The State University of New Jersey Rutgers Method for stably transforming plastids of multicellular plants
US5877402A (en) 1990-05-01 1999-03-02 Rutgers, The State University Of New Jersey DNA constructs and methods for stably transforming plastids of multicellular plants and expressing recombinant proteins therein
US7135614B1 (en) 1990-08-30 2006-11-14 Cargill, Incorporated Brassica or helianthus plants having mutant delta-12 or delta-15 sequences
US5861187A (en) 1990-08-30 1999-01-19 Cargill, Incorporated Oil from canola seed with altered fatty acid profiles and a method of producing oil
US5518908A (en) 1991-09-23 1996-05-21 Monsanto Company Method of controlling insects
PH31293A (en) 1991-10-10 1998-07-06 Rhone Poulenc Agrochimie Production of y-linolenic acid by a delta6-desaturage.
US6355861B1 (en) 1991-10-10 2002-03-12 Rhone-Poulenc Agrochimie Production of gamma linolenic acid by a Δ6-desaturase
US6683232B1 (en) 1991-10-10 2004-01-27 Rhone-Poulenc Agrochimie Production of γ linolenic acid by a Δ6-desaturase
US5614393A (en) 1991-10-10 1997-03-25 Rhone-Poulenc Agrochimie Production of γ-linolenic acid by a Δ6-desaturase
DE69233118T2 (de) 1991-12-04 2004-04-15 E.I. Du Pont De Nemours And Co., Wilmington Fettsäure-desaturase gene aus pflanzen
US5593874A (en) 1992-03-19 1997-01-14 Monsanto Company Enhanced expression in plants
US5798259A (en) 1992-05-15 1998-08-25 Sagami Chemical Research Center Gene coding for eicosapentaenoic acid synthesizing enzymes and process for production of eicosapentaenoic acid
US5683898A (en) 1992-05-15 1997-11-04 Sagami Chemical Research Center Gene coding for eicosapentaenoic acid synthesizing enzymes and process for production of eicosapentaenoic acid
CA2113557A1 (en) 1992-05-15 1993-11-25 Kazunaga Yazawa Gene which codes for eicosapentaenoic acid synthetase group and process for producing eicosapentaenoic acid
US6872872B1 (en) 1992-11-17 2005-03-29 E. I. Du Pont De Nemours And Company Genes for microsomal delta-12 fatty acid desaturases and related enzymes from plants
US6372965B1 (en) 1992-11-17 2002-04-16 E.I. Du Pont De Nemours And Company Genes for microsomal delta-12 fatty acid desaturases and hydroxylases from plants
EP0688160B1 (en) 1993-03-11 1998-05-13 National Research Council Of Canada Enhanced regeneration system for cereals
CA2092588C (en) 1993-03-26 2008-07-08 Narender S. Nehra Enhanced regeneration system for cereals
US5362865A (en) 1993-09-02 1994-11-08 Monsanto Company Enhanced expression in plants using non-translated leader sequences
GB9324707D0 (en) 1993-12-02 1994-01-19 Olsen Odd Arne Promoter
GB9403512D0 (en) 1994-02-24 1994-04-13 Olsen Odd Arne Promoter
US5545818A (en) 1994-03-11 1996-08-13 Calgene Inc. Expression of Bacillus thuringiensis cry proteins in plant plastids
DE4435392B4 (de) 1994-10-04 2008-02-07 Immuno Ag Verfahren zur Trennung von vWF in hochmolekularen vWF und niedermolekularen vWF
GB9515941D0 (en) 1995-08-03 1995-10-04 Zeneca Ltd DNA constructs
AU6547496A (en) 1995-07-28 1997-02-26 Henkel Corporation Polyester oligomer acrylates
WO1997021340A1 (en) 1995-12-14 1997-06-19 Cargill, Incorporated Plants having mutant sequences that confer altered fatty acid profiles
US7541519B2 (en) 1995-12-14 2009-06-02 Cargill, Incorporated Fatty acid desaturases and mutant sequences thereof
US6342658B1 (en) 1995-12-14 2002-01-29 Cargill, Incorporated Fatty acid desaturases and mutant sequences thereof
TR199800294T1 (xx) 1996-06-21 1999-10-21 Monsanto Company Sabit transforme edilen verimli bu�day �retim y�ntemleri.
CA2259942A1 (en) 1996-07-10 1998-01-15 Sagami Chemical Research Center Process for producing icosapentaenoic acid by genetic recombination
US7109392B1 (en) 1996-10-09 2006-09-19 Cargill, Incorporated Methods for increasing oleic acid content in seeds from transgenic plants containing a mutant delta 12 desaturase
WO1998018952A1 (fr) 1996-10-30 1998-05-07 Nippon Suisan Kaisha, Ltd. Procede de production de matieres grasses contenant des acides gras hautement insatures contenant eux-memes un acide docosahexaenoique a concentration selective
US6194167B1 (en) 1997-02-18 2001-02-27 Washington State University Research Foundation ω-3 fatty acid desaturase
AT406373B (de) 1997-02-27 2000-04-25 Immuno Ag Verfahren zur reinigung von faktor viii/vwf-komplex mittels kationenaustauscherchromatographie
WO1998039468A1 (fr) 1997-03-04 1998-09-11 Suntory Limited Procede pour preparer un acide gras hautement insature (aghi) et lipide contenant cet aghi
US5977436A (en) 1997-04-09 1999-11-02 Rhone Poulenc Agrochimie Oleosin 5' regulatory region for the modification of plant seed lipid composition
US5972664A (en) 1997-04-11 1999-10-26 Abbott Laboratories Methods and compositions for synthesis of long chain poly-unsaturated fatty acids
US6428990B1 (en) 1997-04-11 2002-08-06 Abbott Laboratories Human desaturase gene and uses thereof
US6432684B1 (en) 1997-04-11 2002-08-13 Abbott Laboratories Human desaturase gene and uses thereof
US6051754A (en) 1997-04-11 2000-04-18 Abbott Laboratories Methods and compositions for synthesis of long chain poly-unsaturated fatty acids in plants
DK0996732T3 (da) 1997-04-11 2005-10-17 Calgene Llc Fremgangsmåder og sammensætninger til syntese af langkædede polyumættede fedtsyrer i planter
US5968809A (en) 1997-04-11 1999-10-19 Abbot Laboratories Methods and compositions for synthesis of long chain poly-unsaturated fatty acids
US6075183A (en) 1997-04-11 2000-06-13 Abbott Laboratories Methods and compositions for synthesis of long chain poly-unsaturated fatty acids in plants
US7589253B2 (en) 1997-04-15 2009-09-15 Commonwealth Scientific And Industrial Research Organisation Fatty acid epoxygenase genes from plants and uses therefor in modifying fatty acid metabolism
US6235529B1 (en) 1997-04-29 2001-05-22 The Regents Of The University Of California Compositions and methods for plant transformation and regeneration
IN1998CH01219A (en) 1997-06-04 2005-03-04 Calgene Llc Production of polyunsaturated fatty acid by expression of polyketide-like synthesis genes in plants
US6566583B1 (en) 1997-06-04 2003-05-20 Daniel Facciotti Schizochytrium PKS genes
CA2293810C (en) 1997-06-12 2010-03-09 Lorin R. Debonte Fatty acid desaturases and mutant sequences thereof
ZA986574B (en) 1997-07-23 2000-01-12 Sanford Scient Inc Improved plastid transformation of higher plants and production of transgenic plants with herbicide resistance.
US5912416A (en) 1997-08-05 1999-06-15 California Oils Corporation Safflower products with very high levels of unsaturated fatty acids
DE69840362D1 (de) 1997-09-12 2009-01-29 Commw Scient Ind Res Org Regulation der genexpression in pflanzen
DE69836552T3 (de) 1997-09-30 2014-10-09 The Regents Of The University Of California Herstellung von proteinen in pflanzensamen
GB9724783D0 (en) 1997-11-24 1998-01-21 Inst Arable Crops Research Novel polypeptides
AU1774899A (en) 1997-12-23 1999-07-19 University Of Bristol, The Desaturase
US20030152983A1 (en) 1997-12-23 2003-08-14 University Of Bristol Desaturase
US6100447A (en) 1998-02-12 2000-08-08 Applied Phytologics, Inc. Method of barley transformation
US6838594B1 (en) 1998-03-20 2005-01-04 E. I. Du Pont De Nemours And Company Limnanthes oil genes
JP2002528048A (ja) 1998-03-20 2002-09-03 イー・アイ・デュポン・ドウ・ヌムール・アンド・カンパニー リムナンテス属油の遺伝子
US6492108B1 (en) 1998-03-26 2002-12-10 Incyte Genomics, Inc. Delta-6 desaturase homologs
CA2329159A1 (en) 1998-05-29 1999-12-02 Bruce Kelder Compositions and methods for the synthesis of fatty acids, their derivatives and downstream products
CA2330024C (en) 1998-06-12 2012-01-24 Calgene Llc Polyunsaturated fatty acids in plants
AU4564399A (en) 1998-06-12 1999-12-30 Abbott Laboratories Polyunsaturated fatty acids in plants
BR9913382A (pt) 1998-08-20 2001-09-25 Du Pont Fragmentos de ácido nucléico isolados codificadores de uma enzima modificadora de ácidos graxos vegetais associada com a formação de uniões duplas conjugadas, genes quiméricos, células hospedeiras transformadas, sementes, óleos, métodos de alteração do nìvel de ácidos graxos com uniões duplas conjugadas em uma célula hospedeira, métodos de produção de óleo de sementes contendo ácidos graxos com uniões duplas conjugadas nas sementes de plantas, métodos de produção de enzimas modificadoras de ácidos graxos associadas com a formação de uniões duplas conjugadas, métodos de isolamento de fragmentos de ácidos nucléicos e seus subfragmentos funcionalmente equivalentes codificadores de uma enzima modificadora de ácidos graxos vegetais associada a formação de uniões duplas conjugadas, alimento animal, métodos de aprimoramento da qualidade de carcaça de um animal e complemento
WO2000011012A1 (en) 1998-08-24 2000-03-02 Rutgers, The State University Of New Jersey Synthetic fatty acid desaturase gene for expression in plants
US6677145B2 (en) 1998-09-02 2004-01-13 Abbott Laboratories Elongase genes and uses thereof
US6913916B1 (en) 1998-09-02 2005-07-05 Abbott Laboratories Elongase genes and uses thereof
US20030163845A1 (en) 1998-09-02 2003-08-28 Pradip Mukerji Elongase genes and uses thereof
US6403349B1 (en) 1998-09-02 2002-06-11 Abbott Laboratories Elongase gene and uses thereof
WO2000020602A2 (en) 1998-10-05 2000-04-13 Abbott Laboratories Delta 6 and delta 12 desaturases and modified fatty acid biosynthesis and products produced therefrom
WO2000020603A1 (en) 1998-10-05 2000-04-13 Abbott Laboratories Altered fatty acid biosynthesis in insect cells using delta five desaturase
US6609661B1 (en) 1998-10-06 2003-08-26 Kabushiki Kaisha Nippon Conlux Bank-note processing device
JP2002527051A (ja) 1998-10-09 2002-08-27 メルク エンド カムパニー インコーポレーテッド デルタ６脂肪酸デサチュラーゼ
JP4182192B2 (ja) 1998-11-26 2008-11-19 独立行政法人産業技術総合研究所 イコサペンタエン酸及び／又はドコサヘキサエン酸の生合成に関与する酵素群をコードする遺伝子
US6864077B1 (en) 1998-12-03 2005-03-08 Edgar B. Cahoon Membrane-bound desaturases
JP2001095588A (ja) 1998-12-04 2001-04-10 Research Institute Of Innovative Technology For The Earth 緑藻のω３脂肪酸不飽和化酵素遺伝子及びその利用
US6825017B1 (en) 1998-12-07 2004-11-30 Washington State University Research Foundation Desaturases and methods of using them for synthesis of polyunsaturated fatty acids
US20070244192A1 (en) 1999-01-14 2007-10-18 Martek Biosciences Corporation Plant seed oils containing polyunsaturated fatty acids
US7217856B2 (en) 1999-01-14 2007-05-15 Martek Biosciences Corporation PUFA polyketide synthase systems and uses thereof
US7271315B2 (en) 1999-01-14 2007-09-18 Martek Biosciences Corporation PUFA polyketide synthase systems and uses thereof
US7211418B2 (en) 1999-01-14 2007-05-01 Martek Biosciences Corporation PUFA polyketide synthase systems and uses thereof
US8003772B2 (en) 1999-01-14 2011-08-23 Martek Biosciences Corporation Chimeric PUFA polyketide synthase systems and uses thereof
US7247461B2 (en) 1999-01-14 2007-07-24 Martek Biosciences Corporation Nucleic acid molecule encoding ORFA of a PUFA polyketide synthase system and uses thereof
EP1159435A1 (en) 1999-03-05 2001-12-05 Monsanto Technology LLC Multigene expression vectors for the biosynthesis of products via multienzyme biological pathways
EP1035207A1 (en) 1999-03-09 2000-09-13 MultiGene Biotech GmbH cDNA molecules of the members of gene family encoding human fatty acid desaturases and their use in diagnosis and therapy
JP2002538826A (ja) 1999-03-18 2002-11-19 ザ ユニバーシティ オブ ブリストル カエノラブジチス・エレガンス由来の多飽和脂肪酸（ｐｕｆａ）エロンガーゼ
CN1369012A (zh) 1999-06-07 2002-09-11 巴斯夫植物科学股份有限公司 角齿藓△6－乙炔酶和△6－脱饱和酶
EP1190080A1 (de) 1999-07-06 2002-03-27 BASF Plant Science GmbH $g(D)6-DESATURASEGENE EXPRIMIERENDE PFLANZEN UND PUFAS ENTHALTENDE ÖLE AUS DIESEN PFLANZEN UND EIN VERFAHREN ZUR HERSTELLUNG UNGESÄTTIGTER FETTSÄUREN
WO2001004636A1 (en) 1999-07-12 2001-01-18 Ohio University Mammalian cells expressing desaturases and elongases
JP3648134B2 (ja) 1999-07-13 2005-05-18 Ａｂｂ株式会社 自動塗装装置
US7070970B2 (en) 1999-08-23 2006-07-04 Abbott Laboratories Elongase genes and uses thereof
US7531718B2 (en) 1999-08-26 2009-05-12 Monsanto Technology, L.L.C. Nucleic acid sequences and methods of use for the production of plants with modified polyunsaturated fatty acids
CA2382693C (en) 1999-08-26 2013-10-01 Calgene Llc Nucleic acid sequences and methods of use for the production of plants with modified polyunsaturated fatty acids
US7067722B2 (en) 1999-08-26 2006-06-27 Monsanto Technology Llc Nucleic acid sequences and methods of use for the production of plants with modified polyunsaturated fatty acids
DE50015025D1 (de) 1999-09-10 2008-04-17 Nutrinova Gmbh Nukleinsäure aus tetrahymena kodierend fuer eine delta 6-desaturase, ihre herstellung und verwendung
FR2798391B1 (fr) 1999-09-15 2001-12-14 Inst Nat Sante Rech Med Enzyme thyroidienne nadph oxydase, acide nucleique codant pour cette enzyme et leurs applications
DE19950589A1 (de) 1999-10-20 2001-05-23 Gvs Ges Fuer Erwerb Und Verwer Elongasepromotoren für gewebespezifische Expression von Transgenen in Pflanzen
JP4221476B2 (ja) 1999-11-19 2009-02-12 独立行政法人産業技術総合研究所 イコサペンタエン酸生合成遺伝子群をクローニングしたプラスミド及びイコサペンタエン酸を産生するラン藻
IL149388A0 (en) 1999-11-22 2002-11-10 Plant Bioscience Ltd Enhanced transgene expression by co-expression with a suppressor of post-transcriptional gene silencing (ptgs)
US6620986B1 (en) 1999-11-23 2003-09-16 The United States Of America As Represented By The Secretary Of Agriculture Transformation of Ricinus communis, the castor plant
AU1499601A (en) 1999-11-25 2001-06-04 Basf Plant Science Gmbh Moss genes from physcomitrella patents encoding proteins involved in the synthesis of polyunsaturated fatty acids and lipids
JP2001169780A (ja) 1999-12-15 2001-06-26 Natl Inst Of Advanced Industrial Science & Technology Meti ドコサヘキサエン酸生産細菌の遺伝子
GB9929681D0 (en) 1999-12-15 2000-02-09 Implyx Ltd Transgenic insect
GB9929897D0 (en) 1999-12-18 2000-02-09 Slabas Antoni R Improvements in or relating to conjugated fatty acids and related compounds
US20030172398A1 (en) 1999-12-21 2003-09-11 Browse John A. Novel delta-12 desaturase and methods of using it for synthesis of polyunsaturated fatty acids
AU2001239244B2 (en) 2000-02-09 2006-06-08 Basf Aktiengesellschaft Novel elongase gene and method for producing multiple-unsaturated fatty acids
US7411054B2 (en) 2000-03-07 2008-08-12 Millennium Pharmaceuticals, Inc. 25869, 25934, 26335, 50365, 21117, 38692, 46508, 16816, 16839, 49937, 49931 and 49933 molecules and uses therefor
US6686185B1 (en) 2000-03-07 2004-02-03 Millennium Pharmaceuticals, Inc. 25934, a novel fatty acid desaturase and uses therefor
US20040157221A9 (en) 2000-03-07 2004-08-12 Millennium Pharmaceuticals, Inc. Novel 25869, 25934, 26335, 50365, 21117, 38692, 46508, 16816, 16839, 49937, 49931 and 49933 molecules and uses therefor
US20020115178A1 (en) 2000-07-17 2002-08-22 Rachel Meyers 16816 and 16839, novel human phospholipase C molecules and uses therefor
US20020111307A1 (en) 2000-06-23 2002-08-15 Glucksmann Maria Alexandra 46508, a novel human peptidyl-tRNA hydrolase family member and uses thereof
US6492577B1 (en) 2000-03-16 2002-12-10 The Regents Of The University Of California Leafy cotyledon2 genes and their uses
CA2301158A1 (en) 2000-03-24 2001-09-24 Stephen J. Allen Screening methods for compounds useful for modulating lipid metabolism in disease
AU2001247782A1 (en) 2000-03-24 2001-10-08 Millennium Pharmaceuticals, Inc. 18221, dual specificity phosphatase and uses thereof
AU2000234588A1 (en) 2000-03-31 2001-10-15 Idemitsu Petrochemical Co. Ltd. Process for producing lipids and lipid-secreting microorganisms
AU5016301A (en) 2000-04-18 2001-10-30 Commw Scient Ind Res Org Method of modifying the content of cottonseed oil
WO2001087140A2 (en) 2000-05-16 2001-11-22 Crosetto Dario B Method and apparatus for anatomical and functional medical imaging
US7091005B2 (en) 2000-05-16 2006-08-15 Merck & Co., Inc. Gene responsible for Stargardt-like dominant macular dystrophy
AU2001263360A1 (en) 2000-05-19 2001-12-03 Millennium Pharmaceuticals, Inc. 50365, a hexokinase family member and uses thereof
AU2001263473A1 (en) 2000-05-26 2001-12-11 Washington State University Research Foundation Palmitate desaturase gene
WO2001096363A1 (en) 2000-06-12 2001-12-20 Boyce Thompson Institute For Plant Research Fatty acid desaturase gene and protein for modulating activation of defense signaling pathways in plants
EP1297155A2 (en) 2000-06-29 2003-04-02 Millennium Pharmaceuticals, Inc. 25869, a human carboxylesterase and uses thereof
GB0316629D0 (en) 2003-07-16 2003-08-20 Univ York Transgenic cell
AU2001286621A1 (en) 2000-08-21 2002-03-04 Millennium Pharmaceuticals, Inc. Human transporter family members and uses thereof
US7232662B2 (en) 2000-09-26 2007-06-19 Xenon Pharmaceuticals Inc. Methods and compositions employing a novel stearoyl-CoA desaturase-hSCD5
PT1322752E (pt) 2000-09-28 2010-05-06 Bioriginal Food & Science Corp Fad4, fad5, fad5-2 e fad6, novos membros da família de dessaturases de ácidos gordos e susas utilizações
CA2430201A1 (en) 2000-11-27 2002-11-14 Focus Technologies, Inc. Functional protein expression for rapid cell-free phenotyping
US7297523B2 (en) 2000-11-29 2007-11-20 Xenon Pharmaceuticals Inc. Human elongase genes and uses thereof
DE10102338A1 (de) 2001-01-19 2002-07-25 Basf Plant Science Gmbh Verfahren zur Expression von Biosynthesegenen in pflanzlichen Samen unter Verwendung von neuen multiplen Expressionskonstrukten
DE10102337A1 (de) 2001-01-19 2002-07-25 Basf Plant Science Gmbh Verfahren zur Herstellung mehrfach ungesättigter Fettsäuren, neue Biosynthesegene sowie neue pflanzliche Expressionskonstrukte
CA2435685C (en) 2001-01-25 2011-06-07 Abbott Laboratories Desaturase genes and uses thereof
US6635451B2 (en) 2001-01-25 2003-10-21 Abbott Laboratories Desaturase genes and uses thereof
DE10106660A1 (de) 2001-02-12 2002-08-29 Celanese Ventures Gmbh Verfahren zur Herstellung von gamma-Linolensäure aus einer Ciliaten-Kultur durch Zusatz geeigneter Vorläufermoleküle zu dem Kulturmedium
GB0107510D0 (en) 2001-03-26 2001-05-16 Univ Bristol New elongase gene and a process for the production of -9-polyunsaturated fatty acids
WO2002081702A1 (en) 2001-04-05 2002-10-17 Idemitsu Technofine Co., Ltd. Fatty acid δ6-position desaturase genes and plasmids and tra nsformant containing these genes
TWI324181B (en) 2001-04-16 2010-05-01 Martek Biosciences Corp Product and process for transformation of thraustochytriales microorganisms
TWI426127B (zh) 2001-04-16 2014-02-11 Dsm Ip Assets Bv 多不飽和脂肪酸（ｐｕｆａ）聚乙醯合成酶系統及其用途（三）
US20030082754A1 (en) 2001-05-04 2003-05-01 Pradip Mukerji Delta4 - desaturase genes and uses thereof
US7045683B2 (en) 2001-05-04 2006-05-16 Abbott Laboratories Δ4-desaturase genes and uses thereof
US20050129739A1 (en) 2001-05-14 2005-06-16 Gerhard Kohn Production and use of a polar lipid-rich fraction containing omega-3 and/or omega-6 highly unsaturated fatty acids from microbes, genetically modified plant seeds and marine organisms
ES2312620T3 (es) 2001-06-06 2009-03-01 BIORIGINAL FOOD & SCIENCE CORP. Secuencias especificas de la semilla de lino (linum usitatissiumum l.).
DE10134660A1 (de) 2001-07-20 2003-02-06 Basf Plant Science Gmbh Fettsäure-Desaturase-Gene aus Granatapfel und Verfahren zur Herstellung von ungesättigten Fettsäuren
US20050089879A1 (en) 2001-07-31 2005-04-28 Ivo Feussner Method for producing arachidonic acid in transgenic organisms
US6875595B2 (en) 2001-09-13 2005-04-05 Divergence, Inc. Nematode fatty acid desaturase-like sequences
JP2003116566A (ja) 2001-10-12 2003-04-22 Osamu Suzuki ｎ−３系ドコサペンタエン酸の製造方法
EP1472357B1 (de) 2002-01-30 2009-12-16 BASF Plant Science GmbH Verfahren zur herstellung mehrfach ungesättigter fettsäuren mittels eines neuen elongase-gens
US7211656B2 (en) 2002-01-30 2007-05-01 Abbott Laboratories Desaturase genes, enzymes encoded thereby, and uses thereof
GB2385852A (en) 2002-02-27 2003-09-03 Rothamsted Ex Station Delta 6-desaturases from Primulaceae
US7700833B2 (en) 2002-03-01 2010-04-20 Cornell University Process for the production of unsaturated fatty acids
US7705202B2 (en) 2002-03-16 2010-04-27 The University Of York Transgenic plants expressing enzymes involved in fatty acid biosynthesis
US7566813B2 (en) 2002-03-21 2009-07-28 Monsanto Technology, L.L.C. Nucleic acid constructs and methods for producing altered seed oil compositions
DE10219203A1 (de) 2002-04-29 2003-11-13 Basf Plant Science Gmbh Verfahren zur Herstellung mehrfach ungesättigter Fettsäuren in Pflanzen
BR122014000528B1 (pt) 2002-05-22 2016-02-16 Monsanto Technology Llc polinucleotídeo e vetor com atividade dessasturase no carbono 12 de molécula de ácido graxo, bem como método para produção de planta com óleo de semente contendo níveis alterados de ácidos graxos de ômega-3
BR0312162A (pt) 2002-06-21 2007-05-29 Monsanto Technology Llc seqüências de ácido nucléico relacionadas com a tioesterase e processos de uso para a produção de plantas com composição modificada de ácidos graxos
WO2004005442A1 (de) 2002-07-03 2004-01-15 Basf Plant Science Gmbh Verfahren zur herstellung von konjugierten mehrfach ungesättigten fettsäuren mit mindestens zwei doppelbindungen in pflanzen
CN1678321A (zh) 2002-07-29 2005-10-05 里格尔药品股份有限公司 用2,4－嘧啶二胺化合物治疗或者预防自体免疫性疾病的方法
CA2496016A1 (en) 2002-08-12 2004-05-13 Monsanto Technology Llc Methods for increasing total oil levels in plants
CN1675802A (zh) 2002-08-19 2005-09-28 安德森电工产品公司 用于电连接器的手柄锁定系统及其方法
DE10246125A1 (de) 2002-10-01 2004-04-15 Aventis Behring Gmbh Konzentrat eines Faktor VIII:C-haltigen von-Willebrand-Faktors und das dazu gehörige Verfahren
JP4781817B2 (ja) 2002-12-19 2011-09-28 ユニバーシティ オブ ブリストル 多価不飽和脂肪酸類の製造方法
US20040172682A1 (en) 2003-02-12 2004-09-02 Kinney Anthony J. Production of very long chain polyunsaturated fatty acids in oilseed plants
US8084074B2 (en) 2003-02-12 2011-12-27 E. I. Du Pont De Nemours And Company Production of very long chain polyunsaturated fatty acids in oil seed plants
CA2517253C (en) 2003-02-27 2018-07-03 Basf Plant Science Gmbh Method for the production of polyunsaturated fatty acids
CA2868312A1 (en) 2003-03-31 2004-10-14 University Of Bristol Novel plant acyltransferases specific for long-chained, multiply unsaturated fatty acids
DE10315026A1 (de) 2003-04-02 2004-10-14 Bioplanta Arzneimittel Gmbh Zusammensetzungen enthaltend omega-3-fettsäurehaltige Öle und Pflanzenextrakte
JP4732333B2 (ja) 2003-04-08 2011-07-27 ビーエーエスエフ プラント サイエンス ゲーエムベーハー ミドリムシ（Ｅｕｇｌｅｎａｇｒａｃｉｌｉｓ）由来のΔ−４−デサチュラーゼを発現する植物およびＰＵＦＡ含有油
CA2522618A1 (en) 2003-04-16 2004-10-28 Basf Plant Science Gmbh Use of genes for increasing the oil content in plants
US8313911B2 (en) 2003-05-07 2012-11-20 E I Du Pont De Nemours And Company Production of polyunsaturated fatty acids in oleaginous yeasts
US7125672B2 (en) 2003-05-07 2006-10-24 E. I. Du Pont De Nemours And Company Codon-optimized genes for the production of polyunsaturated fatty acids in oleaginous yeasts
US7238482B2 (en) 2003-05-07 2007-07-03 E. I. Du Pont De Nemours And Company Production of polyunsaturated fatty acids in oleaginous yeasts
US20110059496A1 (en) 2003-06-25 2011-03-10 E. I. Du Pont De Nemours And Company Glyceraldehyde-3-phosphate dehydrogenase and phosphoglycerate mutase promoters for gene expression in oleaginous yeast
US7267976B2 (en) 2003-07-02 2007-09-11 E.I. Du Pont De Nemours And Company Acyltransferases for alteration of polyunsaturated fatty acids and oil content in oleaginous yeasts
US7208590B2 (en) 2003-07-15 2007-04-24 Abbott Laboratories Genes involved in polyketide synthase pathways and uses thereof
EP2169052B1 (de) * 2003-08-01 2016-01-06 BASF Plant Science GmbH Verfahren zur Herstellung mehrfach ungesättigter Fettsäuren in transgenen Organismen
PT1656449E (pt) 2003-08-21 2009-07-27 Monsanto Technology Llc Dessaturases dos ácidos gordos a partir de prímulas
US7504259B2 (en) 2003-11-12 2009-03-17 E. I. Du Pont De Nemours And Company Δ12 desaturases suitable for altering levels of polyunsaturated fatty acids in oleaginous yeast
EP1682566B1 (en) 2003-11-12 2013-06-05 E.I. Du Pont De Nemours And Company Delta-15 desaturases suitable for altering levels of polyunsaturated fatty acids in oleaginous plants and yeast
MY140210A (en) 2003-12-22 2009-11-30 Suntory Holdings Ltd Marchantiales-derived unsaturated fatty acid synthetase genes and use of the same
DE602005010826D1 (de) * 2004-01-30 2008-12-18 Bionovate Ltd Lösungsmittelextraktion von lipiden aus perna canaliculus
CA2556336C (en) 2004-02-17 2015-09-08 The University Of York Desaturase enzymes
EP1720988B1 (de) 2004-02-27 2011-10-12 BASF Plant Science GmbH Verfahren zur herstellung von ungesättigten omega-3-fettsäuren in transgenen organismen
MXPA06009572A (es) 2004-02-27 2007-05-23 Basf Plant Science Gmbh Metodo para la produccion de acidos grasos poliinsaturados en plantas transgenicas.
PL1723220T3 (pl) 2004-02-27 2013-09-30 Basf Plant Science Gmbh Sposób wytwarzania wielokrotnie nienasyconych kwasów tłuszczowych w roślinach transgenicznych
DE102004017370A1 (de) 2004-04-08 2005-10-27 Nutrinova Nutrition Specialties & Food Ingredients Gmbh PUFA-PKS Gene aus Ulkenia
DE102004017369A1 (de) 2004-04-08 2005-11-03 Nutrinova Nutrition Specialties & Food Ingredients Gmbh Screeningverfahren zur Identifizierung von PUFA-PKS in Proben
EP2902021B1 (en) 2004-04-16 2018-11-14 Monsanto Technology LLC Expression of fatty acid desaturases in corn
AU2005235627B2 (en) 2004-04-22 2011-07-07 Commonwealth Scientific And Industrial Research Organisation Synthesis of long-chain polyunsaturated fatty acids by recombinant cells
CA3056163C (en) 2004-04-22 2021-04-06 Commonwealth Scientific And Industrial Research Organisation Synthesis of long-chain polyunsaturated fatty acids by recombinant cells
CN101018862B (zh) * 2004-04-22 2013-10-09 联邦科学技术研究组织 用重组细胞合成长链多不饱和脂肪酸
US7807849B2 (en) 2004-04-22 2010-10-05 Commonwealth Scientific And Industrial Research Organisation Synthesis of long-chain polyunsaturated fatty acids by recombinant cells
ES2351973T3 (es) 2004-06-04 2011-02-14 Fluxome Sciences A/S Células metabólicamente modificadas por ingeniería para la producción de ácidos grasos poliinsaturados.
BRPI0512481A (pt) 2004-06-25 2008-03-11 Du Pont polinucleotìdeo isolado, polipeptìdeo, construção recombinante, célula, yarrowia sp.transformada, métodos para transformar uma célula, produzir uma planta transformada, produzir levedura, produzir ácidos graxos poliinsaturados e produzir pelo menos um ácido graxo poliinsaturados, sementes, óleos, plantas de sementes oleaginosa e alimentos ou rações
DE102004060340A1 (de) 2004-07-16 2006-02-09 Basf Plant Science Gmbh Verfahren zur Erhöhung des Gehalts an mehrfach ungesättigten langkettigen Fettsäuren in transgenen Organismen
JP4587451B2 (ja) 2004-08-20 2010-11-24 サントリーホールディングス株式会社 ω３脂肪酸不飽和化活性を有するポリペプチドおよびそのポリペプチドをコードするポリヌクレオチドならびにそれらの利用
DE102004044421B4 (de) 2004-09-14 2010-06-24 Biotest Ag Verfahren zur Trennung eines von Willebrand Faktors mit einer spezifischen VWF-Aktivität von wenigstens 50 E/mg VWF-Antigen von einem von Willebrand Faktor mit niedriger Aktivität und Verwendung von Hydroxylapatit dafür
GB0421937D0 (en) 2004-10-02 2004-11-03 Univ York Acyl CoA synthetases
US8685679B2 (en) 2004-11-04 2014-04-01 E I Du Pont De Nemours And Company Acyltransferase regulation to increase the percent of polyunsaturated fatty acids in total lipids and oils of oleaginous organisms
US7879591B2 (en) 2004-11-04 2011-02-01 E.I. Du Pont De Nemours And Company High eicosapentaenoic acid producing strains of Yarrowia lipolytica
US7192762B2 (en) 2004-11-04 2007-03-20 E. I. Du Pont De Nemours And Company Mortierella alpina glycerol-3-phosphate o-acyltransferase for alteration of polyunsaturated fatty acids and oil content in oleaginous organisms
US7273746B2 (en) 2004-11-04 2007-09-25 E.I. Dupont De Nemours And Company Diacylglycerol acyltransferases for alteration of polyunsaturated fatty acids and oil content in oleaginous organisms
US20060094102A1 (en) 2004-11-04 2006-05-04 Zhixiong Xue Ammonium transporter promoter for gene expression in oleaginous yeast
US7189559B2 (en) 2004-11-04 2007-03-13 E. I. Du Pont De Nemours And Company Mortierella alpina lysophosphatidic acid acyltransferase homolog for alteration of polyunsaturated fatty acids and oil content in oleaginous organisms
US7198937B2 (en) 2004-11-04 2007-04-03 E. I. Du Pont De Nemours And Company Mortierella alpina diacylglycerol acyltransferase for alteration of polyunsaturated fatty acids and oil content in oleaginous organisms
US7550286B2 (en) 2004-11-04 2009-06-23 E. I. Du Pont De Nemours And Company Docosahexaenoic acid producing strains of Yarrowia lipolytica
WO2006064317A1 (en) 2004-12-14 2006-06-22 Avestha Gengraine Technologies Pvt. Ltd. Recombinant production docosahexaenoic acid (dha) in yeast
DE102004063326A1 (de) 2004-12-23 2006-07-06 Basf Plant Science Gmbh Verfahren zur Herstellung mehrfach ungesättigter Fettsäuren in transgenen Organismen
DE102004062294A1 (de) 2004-12-23 2006-07-06 Basf Plant Science Gmbh Verfahren zur Herstellung von mehrfach ungesättigten langkettigen Fettsäuren in transgenen Organismen
DE102005013779A1 (de) 2005-03-22 2006-09-28 Basf Plant Science Gmbh Verfahren zur Herstellung von mehrfach ungesättigten C20- und C22-Fettsäuren mit mindestens vier Doppelbindungen in transgenen Pflanzen
AU2006249983B2 (en) 2005-05-23 2011-03-17 Arcadia Biosciences, Inc. Safflower with elevated gamma-linolenic acid
WO2006135866A2 (en) 2005-06-10 2006-12-21 Martek Biosciences Corporation Pufa polyketide synthase systems and uses thereof
US20110138495A1 (en) 2005-07-05 2011-06-09 Arthur Weissinger Methods and Compositions for Expressing Proteins In Plants
DE102005038036A1 (de) 2005-08-09 2007-02-15 Basf Plant Science Gmbh Verfahren zur Herstellung von Arachidonsäure und/oder Eicosapentaensäure in transgenen Nutzpflanzen
GB2431158A (en) 2005-10-13 2007-04-18 Rothamsted Res Ltd Process for the production of arachidonic and/or eicosapentaenoic acid
DE102005052551A1 (de) 2005-11-02 2007-05-16 Rothamsted Res Harpenden Verfahren zur Herstellung von y-Linolensäure und/oder Stearidonsäure in transgenen Brassicaceae und Linaceae
US8049062B2 (en) 2005-11-23 2011-11-01 E.I. Du Pont De Nemours And Company Delta-9-elongases and their use in making polyunsaturated fatty acids
WO2007092460A2 (en) 2006-02-03 2007-08-16 The Texas A & M University System Enhancing expression of value-added genes by transgenic expression of tombusvirus-based p19 gene mutants
GB0603160D0 (en) 2006-02-16 2006-03-29 Rothamsted Res Ltd Nucleic acid
AR059376A1 (es) 2006-02-21 2008-03-26 Basf Plant Science Gmbh Procedimiento para la produccion de acidos grasos poliinsaturados
WO2007106903A2 (en) 2006-03-15 2007-09-20 Martek Biosciences Corporation Polyunsaturated fatty acid production in heterologous organisms using pufa polyketide synthase systems
US7943823B2 (en) 2006-04-28 2011-05-17 E.I. Du Pont De Nemours And Company Delta-8 desaturase and its use in making polyunsaturated fatty acids
EP2013335A2 (en) 2006-05-01 2009-01-14 E.I. Du Pont De Nemours And Company Fungal delta12 desaturase and delta15 desaturase motifs
CA2648886C (en) 2006-05-29 2015-10-20 Icon Genetics Gmbh Plant virus-based inducible expression system
RU2483057C2 (ru) * 2006-06-28 2013-05-27 Ньюселис Инк. Смеси жирных кислот и их применение
DE102006034313A1 (de) 2006-07-21 2008-01-24 Basf Plant Science Gmbh Verfahren zur Herstellung von Arachidonsäure und/oder Eicosapentaensäure
EP2500420B1 (en) 2006-08-24 2016-06-22 BASF Plant Science GmbH Pythium omega 3 desaturase with specificity to all omega 6 fatty acids longer than 18 carbon chains
CN101578363A (zh) 2006-08-29 2009-11-11 联邦科学技术研究组织 脂肪酸的合成
EP2182056B1 (de) 2006-10-06 2015-12-23 BASF Plant Science GmbH Verfahren zur Herstellung mehrfach ungesättigter Fettsäuren in transgenen nicht-humanen Organismen
US8916361B2 (en) 2006-11-17 2014-12-23 Abbott Laboratories Elongase gene and uses thereof
US7709239B2 (en) 2006-12-07 2010-05-04 E.I. Du Pont De Nemours And Company Mutant Δ8 desaturase genes engineered by targeted mutagenesis and their use in making polyunsaturated fatty acids
US8828690B2 (en) 2007-04-03 2014-09-09 E I Du Pont De Nemours And Company Multizymes comprising delta-9 elongase and delta-8 desaturase and their use in making polyunsaturated fatty acids
US8119860B2 (en) 2007-04-16 2012-02-21 E. I. Du Pont De Nemours And Company Delta-9 elongases and their use in making polyunsaturated fatty acids
US7943365B2 (en) 2007-05-03 2011-05-17 E.I. Du Pont De Nemours And Company Δ-5 desaturases and their use in making polyunsaturated fatty acids
US8785163B2 (en) 2007-07-31 2014-07-22 Basf Plant Science Gmbh Desaturases and methods for producing polyunsaturated fatty acids in transgenic organisms
AU2008281760B2 (en) 2007-07-31 2014-07-17 Basf Plant Science Gmbh Elongases and methods for producing polyunsaturated fatty acids in transgenic organisms
CA2700008A1 (en) 2007-08-01 2009-02-05 Bioglow Inc. Bioluminescent plants comprising bacterial lux operon and methods of making same
US8119784B2 (en) 2008-04-02 2012-02-21 E. I. Du Pont De Nemours And Company Delta-4 desaturase and its use in making polyunsaturated fatty acids
CA2722275A1 (en) 2008-04-25 2009-10-29 Commonwealth Scientific And Industrial Research Organisation Polypeptides and methods for producing triacylglycerols comprising modified fatty acids
EP2271223A2 (de) 2008-04-25 2011-01-12 BASF Plant Science GmbH Pflanzensamenöl
EP2281051B1 (en) 2008-04-30 2015-03-11 Rothamsted Research Limited Desaturase and method for the production of polyunsaturated fatty acids in transgenic organisms
AU2009253939B2 (en) 2008-06-03 2015-08-20 Basf Plant Science Gmbh Fatty acid dehydratases and uses thereof
US8168858B2 (en) 2008-06-20 2012-05-01 E. I. Du Pont De Nemours And Company Delta-9 fatty acid elongase genes and their use in making polyunsaturated fatty acids
AU2009265795B2 (en) 2008-07-01 2014-12-11 Basf Plant Science Gmbh Promoters from Brassica napus for seed specific gene expression
CN102202498B (zh) 2008-07-21 2016-09-07 澳大利亚联邦科学与工业研究组织 改良的棉籽油及应用
CA2768737A1 (en) 2008-07-21 2010-01-28 Commonwealth Scientific And Industrial Research Organisation Improved vegetable oils and uses therefor
EP2156744A1 (en) * 2008-08-11 2010-02-24 Nestec S.A. Oil containing one or more long-chain polyunsaturated fatty acids phospholipids derived from biomass
US9090902B2 (en) 2008-08-26 2015-07-28 Basf Plant Science Gmbh Nucleic acids encoding desaturases and modified plant oil
DK2337791T3 (da) 2008-10-14 2013-11-04 Monsanto Technology Llc Anvendelse af fedtsyredesaturaser fra Hemiselmis SPP
ES2644883T3 (es) 2008-11-18 2017-11-30 Commonwealth Scientific And Industrial Research Organisation Enzimas y métodos para producir ácidos grasos omega-3
EP2376638B1 (en) 2008-12-12 2013-08-14 BASF Plant Science GmbH Desaturases and process for the production of polyunsaturated fatty acids in transgenic organisms
US9212371B2 (en) 2009-05-13 2015-12-15 Basf Plant Science Company Gmbh Acyltransferases and uses thereof in fatty acid production
EP2443248B1 (en) 2009-06-16 2017-12-27 E. I. du Pont de Nemours and Company IMPROVEMENT OF LONG CHAIN OMEGA-3 AND OMEGA-6 POLYUNSATURATED FATTY ACID BIOSYNTHESIS BY EXPRESSION OF ACYL-CoA LYSOPHOSPHOLIPID ACYLTRANSFERASES
AU2010272536B2 (en) 2009-07-17 2016-09-08 Basf Plant Science Company Gmbh Novel fatty acid desaturases and elongases and uses thereof
US8188335B2 (en) 2009-07-17 2012-05-29 Abbott Laboratories Δ9-elongase for production of polyunsaturated fatty acid-enriched oils
JP2013502914A (ja) 2009-08-31 2013-01-31 ビーエーエスエフ プラント サイエンス カンパニー ゲーエムベーハー 多価不飽和脂肪酸合成の増強を促進する植物の種子特異的遺伝子発現を増強する調節核酸分子
WO2011064183A1 (en) 2009-11-24 2011-06-03 Basf Plant Science Company Gmbh Novel fatty acid elongase and uses thereof
US9388436B2 (en) 2009-11-24 2016-07-12 Basf Plant Science Company Gmbh Fatty acid desaturase and uses thereof
TW201144442A (en) 2010-05-17 2011-12-16 Dow Agrosciences Llc Production of DHA and other LC-PUFAs in plants
WO2012000026A1 (en) 2010-06-28 2012-01-05 Commonwealth Scientific And Industrial Research Organisation Methods of producing lipids
US9062315B2 (en) 2010-10-01 2015-06-23 Kyushu University, National University Corporation Method for transformation of stramenopile
EP2695936B1 (en) 2010-10-21 2016-04-20 BASF Plant Science Company GmbH Novel fatty acid desaturases and uses thereof
JP5150814B2 (ja) * 2010-10-29 2013-02-27 オプテックス株式会社 三角測距方式の距離検出回路
TW201307553A (zh) 2011-07-26 2013-02-16 Dow Agrosciences Llc 在植物中生產二十二碳六烯酸（ｄｈａ）及其他長鏈多元不飽和脂肪酸（ｌｃ－ｐｕｆａ）之技術
CA3148246A1 (en) 2012-04-12 2013-10-17 Rothamsted Research Ltd Production of omega-3 long chain polyunsaturated fatty acids
SG11201408362SA (en) 2012-06-15 2015-01-29 Commw Scient Ind Res Org Production of long chain polyunsaturated fatty acids in plant cells
EP2880050B1 (en) 2012-08-03 2018-07-04 BASF Plant Science Company GmbH Novel enzymes, enzyme components and uses thereof
GB201217524D0 (en) 2012-10-01 2012-11-14 Rothamsted Res Ltd Recombinant organisms
CA2933909A1 (en) 2013-12-18 2015-06-25 Grains Research And Development Corporation Lipid comprising long chain polyunsaturated fatty acids
CA2953008C (en) 2014-06-27 2024-03-19 Nuseed Pty Ltd Lipid comprising docosapentaenoic acid

Also Published As

Publication number Publication date
EP2861059B1 (en) 2017-05-03
KR20150037771A (ko) 2015-04-08
PH12014502795A1 (en) 2015-02-09
US20200369980A1 (en) 2020-11-26
BR122019026149A8 (pt) 2022-06-28
KR20200083595A (ko) 2020-07-08
PT2861059T (pt) 2017-08-08
NZ631702A (en) 2017-01-27
JP2020172643A (ja) 2020-10-22
EP2861059A4 (en) 2016-03-09
IL236288A0 (en) 2015-02-26
CL2019002477A1 (es) 2019-12-06
PE20150769A1 (es) 2015-06-11
US20240084214A1 (en) 2024-03-14
US11306271B2 (en) 2022-04-19
US20180258026A1 (en) 2018-09-13
CL2014003402A1 (es) 2015-12-11
US20150045569A1 (en) 2015-02-12
US20170349528A1 (en) 2017-12-07
AU2018247287A1 (en) 2018-11-01
ES2636487T3 (es) 2017-10-05
US11834621B2 (en) 2023-12-05
US8946460B2 (en) 2015-02-03
MX2014015375A (es) 2016-02-18
PE20200448A1 (es) 2020-02-28
AU2013273934B2 (en) 2016-12-01
UA127917C2 (uk) 2024-02-14
BR112014031362A8 (pt) 2022-06-28
EA036786B1 (ru) 2020-12-21
US20210139809A1 (en) 2021-05-13
US20180008568A1 (en) 2018-01-11
CA3082388A1 (en) 2013-12-19
JP2015528027A (ja) 2015-09-24
US20170320806A1 (en) 2017-11-09
US9550718B2 (en) 2017-01-24
US9999607B2 (en) 2018-06-19
WO2013185184A3 (en) 2014-02-13
CN104853596A (zh) 2015-08-19
EP2861059A2 (en) 2015-04-22
US20170334826A1 (en) 2017-11-23
US20130338388A1 (en) 2013-12-19
AU2013273934A1 (en) 2015-01-22
DK2861059T3 (en) 2017-08-28
PL2861059T3 (pl) 2017-10-31
JP6784656B2 (ja) 2020-11-11
HUE033766T2 (en) 2018-01-29
US9969954B2 (en) 2018-05-15
JP7254744B2 (ja) 2023-04-10
HK1248989A1 (zh) 2018-10-26
JP6242882B2 (ja) 2017-12-06
EP3266316A1 (en) 2018-01-10
US20130338387A1 (en) 2013-12-19
IL236288A (en) 2016-06-30
EA201590026A1 (ru) 2015-05-29
AU2018247287B2 (en) 2021-08-19
CN109294730B (zh) 2021-09-21
AU2017201411B2 (en) 2018-07-12
MY187101A (en) 2021-08-31
US20220356414A1 (en) 2022-11-10
CA2876519A1 (en) 2013-12-19
MX349678B (es) 2017-08-08
US9932289B2 (en) 2018-04-03
US10899992B2 (en) 2021-01-26
US9932290B2 (en) 2018-04-03
US9932541B2 (en) 2018-04-03
US10655082B2 (en) 2020-05-19
KR102197208B1 (ko) 2021-01-04
SG10201810439SA (en) 2018-12-28
AU2017201411A1 (en) 2017-03-23
CA2876519C (en) 2020-09-15
US9556102B2 (en) 2017-01-31
US8816111B2 (en) 2014-08-26
JP2018075003A (ja) 2018-05-17
US10335386B2 (en) 2019-07-02
BR122019026149A2 (pt) 2017-07-25
SG11201408362SA (en) 2015-01-29
US20170349526A1 (en) 2017-12-07
US20150203788A1 (en) 2015-07-23
CN109294730A (zh) 2019-02-01
CN104853596B (zh) 2018-10-09
UA117223C2 (uk) 2018-07-10
AU2021269427A1 (en) 2021-12-16
ZA201500015B (en) 2016-04-28
US20170349527A1 (en) 2017-12-07
BR112014031362A2 (pt) 2017-07-25
US20180311200A1 (en) 2018-11-01
WO2013185184A2 (en) 2013-12-19

Similar Documents

Publication Publication Date Title
HK1248989A1 (zh) 在植物細胞中產生長鏈多不飽和脂肪酸
IL266231B (en) Compounds of omega-3 polyunsaturated fatty acids are enriched in dpa in the form of fat in the free acid phase
ZA201400054B (en) Production of dha other lc-pufas in plants
SG10201605082RA (en) Production Of Omega-Amino Fatty Acids
IL223045A0 (en) Production of dha and other lc-pufas in plants
IL212112A0 (en) Production of modifird fatty acids in plants
SG11201501013PA (en) Microorganisms and methods for the production of fatty acids and fatty acid derived products
HUE037067T2 (hu) Omega-7 zsírsavak felhalmozódása növényi magvakban
AU2013905033A0 (en) Production of increased levels of long chain polyunsaturated fatty acids in plant cells
GB201222184D0 (en) Production of omega-3 long chain polyunsaturated fatty acids
GB201206483D0 (en) Production of omega-3 long chain polyunsaturated fatty acids
AU2014902471A0 (en) Production of increased levels of long chain polyunsaturated fatty acids in plant cells
GB201217404D0 (en) Method to convert fatty acids
GB201104653D0 (en) Improvements in the manufacture of fatty acids
GB201208974D0 (en) Improvements in the manufacture of fatty acids