HK1208050A1 - Enhanced affinity cell receptors and methods for making he same - Google Patents

Enhanced affinity cell receptors and methods for making he same

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Publication number
HK1208050A1
HK1208050A1 HK15108593.7A HK15108593A HK1208050A1 HK 1208050 A1 HK1208050 A1 HK 1208050A1 HK 15108593 A HK15108593 A HK 15108593A HK 1208050 A1 HK1208050 A1 HK 1208050A1
Authority
HK
Hong Kong
Prior art keywords
making
methods
same
cell receptors
enhanced affinity
Prior art date
Application number
HK15108593.7A
Other languages
English (en)
Chinese (zh)
Inventor
Thomas M Schmitt
Philip D Greenberg
Original Assignee
Hutchinson Fred Cancer Res
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hutchinson Fred Cancer Res filed Critical Hutchinson Fred Cancer Res
Publication of HK1208050A1 publication Critical patent/HK1208050A1/xx

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    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/0081—Purging biological preparations of unwanted cells
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    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
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    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/70503—Immunoglobulin superfamily
    • C07K14/7051—T-cell receptor (TcR)-CD3 complex
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    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
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    • A61K35/14—Blood; Artificial blood
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    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/177—Receptors; Cell surface antigens; Cell surface determinants
    • A61K38/1774—Immunoglobulin superfamily (e.g. CD2, CD4, CD8, ICAM molecules, B7 molecules, Fc-receptors, MHC-molecules)
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    • A61K39/461—Cellular immunotherapy characterised by the cell type used
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    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
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    • C12N5/10—Cells modified by introduction of foreign genetic material
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    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
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  • Proteomics, Peptides & Aminoacids (AREA)
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  • Gastroenterology & Hepatology (AREA)
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  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
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HK15108593.7A 2012-05-03 2015-09-02 Enhanced affinity cell receptors and methods for making he same HK1208050A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201261642358P 2012-05-03 2012-05-03
PCT/US2013/039316 WO2013166321A1 (en) 2012-05-03 2013-05-02 Enhanced affinity t cell receptors and methods for making the same

Publications (1)

Publication Number Publication Date
HK1208050A1 true HK1208050A1 (en) 2016-02-19

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HK15108593.7A HK1208050A1 (en) 2012-05-03 2015-09-02 Enhanced affinity cell receptors and methods for making he same

Country Status (18)

Country Link
US (2) US9751928B2 (ru)
EP (1) EP2844743B1 (ru)
JP (2) JP6251734B2 (ru)
KR (2) KR20150009556A (ru)
CN (2) CN107557334B (ru)
AU (2) AU2013256159B2 (ru)
BR (1) BR112014027374B1 (ru)
CA (1) CA2872471C (ru)
ES (1) ES2858248T3 (ru)
HK (1) HK1208050A1 (ru)
IL (1) IL235355B (ru)
IN (1) IN2014DN09787A (ru)
MX (1) MX361760B (ru)
NZ (1) NZ702108A (ru)
PH (1) PH12014502418A1 (ru)
RU (2) RU2665548C2 (ru)
SG (2) SG10201609210SA (ru)
WO (1) WO2013166321A1 (ru)

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