PT3915659T - Suporte de afinidade - Google Patents

Suporte de afinidade

Info

Publication number
PT3915659T
PT3915659T PT211668488T PT21166848T PT3915659T PT 3915659 T PT3915659 T PT 3915659T PT 211668488 T PT211668488 T PT 211668488T PT 21166848 T PT21166848 T PT 21166848T PT 3915659 T PT3915659 T PT 3915659T
Authority
PT
Portugal
Prior art keywords
affinity support
affinity
support
Prior art date
Application number
PT211668488T
Other languages
English (en)
Original Assignee
Biomolecular Holdings Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Biomolecular Holdings Llc filed Critical Biomolecular Holdings Llc
Publication of PT3915659T publication Critical patent/PT3915659T/pt

Links

Classifications

    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01DSEPARATION
    • B01D15/00Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
    • B01D15/08Selective adsorption, e.g. chromatography
    • B01D15/26Selective adsorption, e.g. chromatography characterised by the separation mechanism
    • B01D15/38Selective adsorption, e.g. chromatography characterised by the separation mechanism involving specific interaction not covered by one or more of groups B01D15/265 - B01D15/36
    • B01D15/3804Affinity chromatography
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4711Alzheimer's disease; Amyloid plaque core protein
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01DSEPARATION
    • B01D15/00Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
    • B01D15/08Selective adsorption, e.g. chromatography
    • B01D15/26Selective adsorption, e.g. chromatography characterised by the separation mechanism
    • B01D15/34Size selective separation, e.g. size exclusion chromatography, gel filtration, permeation
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01DSEPARATION
    • B01D15/00Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
    • B01D15/08Selective adsorption, e.g. chromatography
    • B01D15/26Selective adsorption, e.g. chromatography characterised by the separation mechanism
    • B01D15/38Selective adsorption, e.g. chromatography characterised by the separation mechanism involving specific interaction not covered by one or more of groups B01D15/265 - B01D15/36
    • B01D15/3804Affinity chromatography
    • B01D15/3809Affinity chromatography of the antigen-antibody type, e.g. protein A, G, L chromatography
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01DSEPARATION
    • B01D15/00Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
    • B01D15/08Selective adsorption, e.g. chromatography
    • B01D15/26Selective adsorption, e.g. chromatography characterised by the separation mechanism
    • B01D15/38Selective adsorption, e.g. chromatography characterised by the separation mechanism involving specific interaction not covered by one or more of groups B01D15/265 - B01D15/36
    • B01D15/3847Multimodal interactions
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/281Sorbents specially adapted for preparative, analytical or investigative chromatography
    • B01J20/286Phases chemically bonded to a substrate, e.g. to silica or to polymers
    • B01J20/289Phases chemically bonded to a substrate, e.g. to silica or to polymers bonded via a spacer
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/30Processes for preparing, regenerating, or reactivating
    • B01J20/32Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating
    • B01J20/3202Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating characterised by the carrier, support or substrate used for impregnation or coating
    • B01J20/3204Inorganic carriers, supports or substrates
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/30Processes for preparing, regenerating, or reactivating
    • B01J20/32Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating
    • B01J20/3202Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating characterised by the carrier, support or substrate used for impregnation or coating
    • B01J20/3206Organic carriers, supports or substrates
    • B01J20/3208Polymeric carriers, supports or substrates
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/30Processes for preparing, regenerating, or reactivating
    • B01J20/32Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating
    • B01J20/3214Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating characterised by the method for obtaining this coating or impregnating
    • B01J20/3217Resulting in a chemical bond between the coating or impregnating layer and the carrier, support or substrate, e.g. a covalent bond
    • B01J20/3219Resulting in a chemical bond between the coating or impregnating layer and the carrier, support or substrate, e.g. a covalent bond involving a particular spacer or linking group, e.g. for attaching an active group
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/30Processes for preparing, regenerating, or reactivating
    • B01J20/32Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating
    • B01J20/3231Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating characterised by the coating or impregnating layer
    • B01J20/3242Layers with a functional group, e.g. an affinity material, a ligand, a reactant or a complexing group
    • B01J20/3268Macromolecular compounds
    • B01J20/3272Polymers obtained by reactions otherwise than involving only carbon to carbon unsaturated bonds
    • B01J20/3274Proteins, nucleic acids, polysaccharides, antibodies or antigens
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54353Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals with ligand attached to the carrier via a chemical coupling agent
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6893Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
    • G01N33/6896Neurological disorders, e.g. Alzheimer's disease
    • HELECTRICITY
    • H01ELECTRIC ELEMENTS
    • H01JELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
    • H01J49/00Particle spectrometers or separator tubes
    • H01J49/0027Methods for using particle spectrometers
    • HELECTRICITY
    • H01ELECTRIC ELEMENTS
    • H01JELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
    • H01J49/00Particle spectrometers or separator tubes
    • H01J49/02Details
    • H01J49/10Ion sources; Ion guns
    • H01J49/16Ion sources; Ion guns using surface ionisation, e.g. field-, thermionic- or photo-emission
    • H01J49/161Ion sources; Ion guns using surface ionisation, e.g. field-, thermionic- or photo-emission using photoionisation, e.g. by laser
    • H01J49/164Laser desorption/ionisation, e.g. matrix-assisted laser desorption/ionisation [MALDI]
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/46Assays involving biological materials from specific organisms or of a specific nature from animals; from humans from vertebrates
    • G01N2333/47Assays involving proteins of known structure or function as defined in the subgroups
    • G01N2333/4701Details
    • G01N2333/4703Regulators; Modulating activity

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Physics & Mathematics (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Microbiology (AREA)
  • General Physics & Mathematics (AREA)
  • Biotechnology (AREA)
  • Cell Biology (AREA)
  • Food Science & Technology (AREA)
  • Pathology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Neurology (AREA)
  • Optics & Photonics (AREA)
  • Inorganic Chemistry (AREA)
  • Neurosurgery (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Plasma & Fusion (AREA)
  • Solid-Sorbent Or Filter-Aiding Compositions (AREA)
  • Peptides Or Proteins (AREA)
  • Sampling And Sample Adjustment (AREA)
  • Treatment Of Liquids With Adsorbents In General (AREA)
  • Materials For Medical Uses (AREA)
  • Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
PT211668488T 2012-07-17 2013-06-03 Suporte de afinidade PT3915659T (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP2012158647A JP6231263B2 (ja) 2012-07-17 2012-07-17 アフィニティ支持体及びそれを用いた物質の捕捉方法

Publications (1)

Publication Number Publication Date
PT3915659T true PT3915659T (pt) 2023-11-10

Family

ID=49949164

Family Applications (2)

Application Number Title Priority Date Filing Date
PT138203773T PT2874724T (pt) 2012-07-17 2013-06-03 Suporte de afinidade e método de captura de substância utilizando o mesmo
PT211668488T PT3915659T (pt) 2012-07-17 2013-06-03 Suporte de afinidade

Family Applications Before (1)

Application Number Title Priority Date Filing Date
PT138203773T PT2874724T (pt) 2012-07-17 2013-06-03 Suporte de afinidade e método de captura de substância utilizando o mesmo

Country Status (12)

Country Link
US (3) US10968263B2 (pt)
EP (2) EP3915659B1 (pt)
JP (2) JP6231263B2 (pt)
CA (1) CA2879097C (pt)
DK (2) DK3915659T3 (pt)
ES (2) ES2962141T3 (pt)
FI (1) FI3915659T3 (pt)
HR (1) HRP20210849T1 (pt)
LT (1) LT2874724T (pt)
PT (2) PT2874724T (pt)
SI (1) SI2874724T1 (pt)
WO (1) WO2014014563A1 (pt)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP6231263B2 (ja) * 2012-07-17 2017-11-15 株式会社島津製作所 アフィニティ支持体及びそれを用いた物質の捕捉方法
PT3611180T (pt) 2013-03-15 2022-03-15 Biomolecular Holdings Llc Imunoglobulina híbrida que contém uma ligação não peptídica
US10942190B2 (en) 2014-01-21 2021-03-09 Shimadzu Corporation Measurement method for amyloid precursor protein cleavage peptides
SG11201607579TA (en) 2014-03-14 2016-10-28 Daniel J Capon Hybrid immunoglobulin containing non-peptidyl linkage
EP3262194B1 (en) * 2015-02-25 2020-04-08 Agency for Science, Technology and Research Device and method for detecting target molecules
PL3338094T3 (pl) * 2015-08-20 2019-09-30 F. Hoffmann-La Roche Ag Test immunologiczny oparty na cząstkach z zastosowaniem pegylowanego swoistego względem analitu czynnika wiążącego
CN108333361A (zh) * 2017-01-19 2018-07-27 深圳市新产业生物医学工程股份有限公司 桥连有抗体的磁性微球复合制剂及其制备方法与应用
ES2865511T3 (es) * 2017-02-02 2021-10-15 Hoffmann La Roche Inmunoanálisis que usa al menos dos agentes de unión específica a analito pegilado
JP7156146B2 (ja) * 2019-04-10 2022-10-19 株式会社島津製作所 親水性材料の疎水化方法

Family Cites Families (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5217492A (en) * 1982-09-29 1993-06-08 Bio-Metric Systems, Inc. Biomolecule attachment to hydrophobic surfaces
JP2826965B2 (ja) 1995-01-12 1998-11-18 オリエンタル酵母工業株式会社 免疫吸着体とその製造法
SI1482987T1 (sl) * 2002-03-01 2014-12-31 Bracco Suisse Sa Večvalentni konstrukti za terapevtske in diagnostične aplikacije
US7261876B2 (en) 2002-03-01 2007-08-28 Bracco International Bv Multivalent constructs for therapeutic and diagnostic applications
GB0211805D0 (en) * 2002-05-22 2002-07-03 Prometic Biosciences Ltd Endotoxin-binding ligands and their use
SE526038C2 (sv) * 2002-07-08 2005-06-21 Gambro Lundia Ab Polymeraffinitetsmatris, förfarande för framställning därav och anvädning därav
US20060194715A1 (en) * 2002-10-25 2006-08-31 Blackburn Jonathan M Proteins encoded by ble genes and antibiotics from the bleomycin family
EP1480041A1 (en) * 2003-05-22 2004-11-24 Innogenetics N.V. Method for the prediction, diagnosis and differential diagnosis of Alzheimer's disease
WO2005004809A2 (en) * 2003-07-01 2005-01-20 Immunomedics, Inc. Multivalent carriers of bi-specific antibodies
EP1674486A4 (en) 2003-10-17 2007-07-18 Reverse Proteomics Res Inst Co AFFINITY RESIN
US20070167608A1 (en) * 2003-12-25 2007-07-19 Jun Hirabayashi Sugar chain structure profiling techniques
WO2005119258A1 (ja) * 2004-06-03 2005-12-15 Kimio Katsuta 複数物質同時測定方法およびそれに使用する測定用デバイス
US20070157325A1 (en) * 2005-12-30 2007-07-05 Shahriar Mojtahedian Process for identification of novel disease biomarkers in mouse models of alzheimer's disease including triple transgenic mice and products thereby
JP2008045906A (ja) * 2006-08-11 2008-02-28 Chiba Univ アフィニティビーズおよびその製造方法
JP5224477B2 (ja) 2006-11-01 2013-07-03 ベックマン コールター, インコーポレイテッド 親和性アッセイのための結合表面
KR20090105913A (ko) 2006-11-02 2009-10-07 다니엘 제이 카폰 이동 부분을 갖는 하이브리드 면역글로불린
WO2008065806A1 (fr) 2006-11-29 2008-06-05 Shimadzu Corporation Spectrométrie de masse d'un échantillon biologique par immunoprécipitation
UA95996C2 (ru) * 2007-01-18 2011-09-26 Эли Лилли Энд Компани Пегилированный fab-фрагмент антитела, который специфически связывается с бета-амилоидным пептидом
EP2020602A1 (en) * 2007-08-02 2009-02-04 Araclon Biotech High sensitivty immunoassays and kits for the determination of peptides and proteins of biological interest
US20100233678A1 (en) * 2007-11-13 2010-09-16 Beadling Leslie C Tunable affinity ligands for the separation and detection of target substances
JP5435878B2 (ja) * 2008-02-12 2014-03-05 富士フイルム株式会社 断片化抗体を標識物質に固定した標識粒子
GB0808908D0 (en) * 2008-05-16 2008-06-25 Avecia Biolog Ltd Purification process
JP2013510297A (ja) * 2009-11-04 2013-03-21 ノバルティス アーゲー モノマーからのタンパク質凝集体の分離における結合試薬としての正に荷電した種
WO2012085113A1 (en) * 2010-12-23 2012-06-28 Roche Diagnostics Gmbh Binding agent
CA2876588A1 (en) * 2011-06-20 2012-12-27 Akrivis Technologies, Llc Reagents and methods for bispecific antibody-based binding of target molecules
WO2013065343A1 (ja) 2011-10-31 2013-05-10 株式会社 島津製作所 非ペプチドヒンジ部含有フレキシブル抗体様分子
JP6231263B2 (ja) * 2012-07-17 2017-11-15 株式会社島津製作所 アフィニティ支持体及びそれを用いた物質の捕捉方法
PT3611180T (pt) 2013-03-15 2022-03-15 Biomolecular Holdings Llc Imunoglobulina híbrida que contém uma ligação não peptídica
SG11201607579TA (en) 2014-03-14 2016-10-28 Daniel J Capon Hybrid immunoglobulin containing non-peptidyl linkage

Also Published As

Publication number Publication date
SI2874724T1 (sl) 2021-08-31
US20150177263A1 (en) 2015-06-25
EP3915659B1 (en) 2023-08-02
HRP20210849T1 (hr) 2021-07-09
CA2879097C (en) 2022-07-19
PT2874724T (pt) 2021-05-21
EP2874724B1 (en) 2021-04-07
US10968263B2 (en) 2021-04-06
ES2962141T3 (es) 2024-03-15
EP2874724A1 (en) 2015-05-27
EP2874724A4 (en) 2016-04-06
WO2014014563A1 (en) 2014-01-23
ES2870536T3 (es) 2021-10-27
JP2015529322A (ja) 2015-10-05
CA2879097A1 (en) 2014-01-23
JP6231263B2 (ja) 2017-11-15
DK3915659T3 (da) 2023-11-06
DK2874724T3 (da) 2021-05-25
JP2014020872A (ja) 2014-02-03
EP2874724B8 (en) 2021-05-12
EP3915659A1 (en) 2021-12-01
US20150197549A1 (en) 2015-07-16
FI3915659T3 (fi) 2023-11-03
LT2874724T (lt) 2021-06-25
US20220017583A1 (en) 2022-01-20

Similar Documents

Publication Publication Date Title
HK1201757A1 (en) High affinity sirp-alpha reagents sirp-
AP2015008483A0 (en) Suspension device
EP2836097A4 (en) SUPPORT VEST
EP2884862A4 (en) PELVIC AND BREEZE CLOTHING
PT3915659T (pt) Suporte de afinidade
EP2894171A4 (en) ADSORPTION
EP2843257A4 (en) SUSPENSION DEVICE
EP2829423A4 (en) SUSPENSION DEVICE
GB201222308D0 (en) Support assembly
EP2853768A4 (en) SUSPENSION DEVICE
GB201211399D0 (en) Support poles
PL2912334T3 (pl) Wspornik pneumatyczny
LT2906891T (lt) Gaminio laikiklis
GB2500223B (en) Cable support
GB2507377B (en) Support assembly
GB201217065D0 (en) Cable support
GB201316734D0 (en) Support system
GB201208073D0 (en) Support
GB201223368D0 (en) Support components
GB201208381D0 (en) Support arrangement
IL229737A0 (en) Improved structural support
GB201216832D0 (en) Support structure
GB201207593D0 (en) Suspension
GB201205217D0 (en) Suspension arrangement
GB201204829D0 (en) Support system