HK1183449A1 - 通過用微細分的二氧化硅處理去除絲氨酸蛋白酶 - Google Patents

通過用微細分的二氧化硅處理去除絲氨酸蛋白酶

Info

Publication number
HK1183449A1
HK1183449A1 HK13110932.5A HK13110932A HK1183449A1 HK 1183449 A1 HK1183449 A1 HK 1183449A1 HK 13110932 A HK13110932 A HK 13110932A HK 1183449 A1 HK1183449 A1 HK 1183449A1
Authority
HK
Hong Kong
Prior art keywords
removal
treatment
silicon dioxide
finely divided
serine proteases
Prior art date
Application number
HK13110932.5A
Other languages
English (en)
Inventor
Wolfgang Teschner
Hans-Peter Schwarz
Ruth Madlener
Sonja Svatos
Azra Pljevljakovic
Alfred Weber
Original Assignee
Baxter Int
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=42727304&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=HK1183449(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from US12/842,944 external-priority patent/US8304524B2/en
Priority claimed from PCT/US2011/038247 external-priority patent/WO2011150284A2/en
Application filed by Baxter Int filed Critical Baxter Int
Publication of HK1183449A1 publication Critical patent/HK1183449A1/zh

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/14—Blood; Artificial blood
    • A61K35/16—Blood plasma; Blood serum
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A—HUMAN NECESSITIES
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/1703—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • A61K38/1709—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
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    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/55—Protease inhibitors
    • A61K38/57—Protease inhibitors from animals; from humans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/39516—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum from serum, plasma
    • A61K39/39525—Purification
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
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    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
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    • B01D15/08—Selective adsorption, e.g. chromatography
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    • B—PERFORMING OPERATIONS; TRANSPORTING
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    • B01D15/08—Selective adsorption, e.g. chromatography
    • B01D15/26—Selective adsorption, e.g. chromatography characterised by the separation mechanism
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    • B01D15/361—Ion-exchange
    • B01D15/363—Anion-exchange
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
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    • B01D15/08—Selective adsorption, e.g. chromatography
    • B01D15/42—Selective adsorption, e.g. chromatography characterised by the development mode, e.g. by displacement or by elution
    • B01D15/424—Elution mode
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/02—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof comprising inorganic material
    • B01J20/10—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof comprising inorganic material comprising silica or silicate
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14—Extraction; Separation; Purification
    • C07K1/30—Extraction; Separation; Purification by precipitation
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
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    • C07K1/36—Extraction; Separation; Purification by a combination of two or more processes of different types
    • C—CHEMISTRY; METALLURGY
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/06—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies from serum
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/06—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies from serum
    • C07K16/065—Purification, fragmentation
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14—Extraction; Separation; Purification
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14—Extraction; Separation; Purification
    • C07K1/16—Extraction; Separation; Purification by chromatography
    • C07K1/18—Ion-exchange chromatography
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14—Extraction; Separation; Purification
    • C07K1/34—Extraction; Separation; Purification by filtration, ultrafiltration or reverse osmosis

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  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
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  • Proteomics, Peptides & Aminoacids (AREA)
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HK13110932.5A 2010-05-26 2013-09-25 通過用微細分的二氧化硅處理去除絲氨酸蛋白酶 HK1183449A1 (zh)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
AU2010202125A AU2010202125B1 (en) 2010-05-26 2010-05-26 A method to produce an immunoglobulin preparation with improved yield
US12/789,365 US8993734B2 (en) 2010-05-26 2010-05-27 Method to produce an immunoglobulin preparation with improved yield
US12/842,944 US8304524B2 (en) 2009-07-23 2010-07-23 Manufacture of factor H (FH) and FH-derivatives from plasma
PCT/US2011/038247 WO2011150284A2 (en) 2010-05-26 2011-05-26 Removal of serine proteases by treatment with finely divided silicon dioxide

Publications (1)

Publication Number Publication Date
HK1183449A1 true HK1183449A1 (zh) 2013-12-27

Family

ID=42727304

Family Applications (6)

Application Number Title Priority Date Filing Date
HK12110936.2A HK1170168A1 (zh) 2010-05-26 2012-10-31 用於從血漿中製備富集的免疫球蛋白 組合物的方法
HK13109199.5A HK1181682A1 (zh) 2010-05-26 2013-08-06 從血漿製備富含 的組合物的方法
HK13110932.5A HK1183449A1 (zh) 2010-05-26 2013-09-25 通過用微細分的二氧化硅處理去除絲氨酸蛋白酶
HK15104607.0A HK1203838A1 (zh) 2010-05-26 2015-05-15 從血漿製備富含 的組合物的方法
HK16101817.1A HK1213790A1 (zh) 2010-05-26 2016-02-18 通過用微細分的二氧化矽處理去除絲氨酸蛋白酶
HK16103905.0A HK1215931A1 (zh) 2010-05-26 2016-04-06 從血漿製備富含 的組合物的方法

Family Applications Before (2)

Application Number Title Priority Date Filing Date
HK12110936.2A HK1170168A1 (zh) 2010-05-26 2012-10-31 用於從血漿中製備富集的免疫球蛋白 組合物的方法
HK13109199.5A HK1181682A1 (zh) 2010-05-26 2013-08-06 從血漿製備富含 的組合物的方法

Family Applications After (3)

Application Number Title Priority Date Filing Date
HK15104607.0A HK1203838A1 (zh) 2010-05-26 2015-05-15 從血漿製備富含 的組合物的方法
HK16101817.1A HK1213790A1 (zh) 2010-05-26 2016-02-18 通過用微細分的二氧化矽處理去除絲氨酸蛋白酶
HK16103905.0A HK1215931A1 (zh) 2010-05-26 2016-04-06 從血漿製備富含 的組合物的方法

Country Status (25)

Country Link
US (6) US8993734B2 (zh)
EP (6) EP2803349B1 (zh)
JP (6) JP5876474B2 (zh)
KR (3) KR101593265B1 (zh)
CN (5) CN102970975B (zh)
AR (4) AR076800A1 (zh)
AU (7) AU2010202125B1 (zh)
BR (2) BR112012029893B1 (zh)
CA (2) CA2800155A1 (zh)
CL (3) CL2012003290A1 (zh)
CO (2) CO6660439A2 (zh)
DK (3) DK2554160T3 (zh)
EA (4) EA034602B1 (zh)
ES (4) ES2525492T3 (zh)
HK (6) HK1170168A1 (zh)
HR (3) HRP20140944T1 (zh)
HU (1) HUE064400T2 (zh)
IL (2) IL223149A (zh)
MX (4) MX364252B (zh)
MY (3) MY160551A (zh)
PL (4) PL2554160T3 (zh)
PT (3) PT2554160E (zh)
SG (3) SG10201505161SA (zh)
TW (3) TWI531577B (zh)
WO (1) WO2011149472A1 (zh)

Families Citing this family (45)

* Cited by examiner, † Cited by third party
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TWI489994B (zh) 2008-03-17 2015-07-01 Baxter Healthcare Sa 供免疫球蛋白及玻尿酸酶之皮下投藥之用的組合及方法
JP5734985B2 (ja) * 2009-09-17 2015-06-17 バクスター・ヘルスケヤー・ソシエテ・アノニムＢａｘｔｅｒ Ｈｅａｌｔｈｃａｒｅ ＳＡ ヒアルロニダーゼおよび免疫グロブリンの安定な共製剤およびそれらの使用方法
US10787701B2 (en) 2010-04-05 2020-09-29 Prognosys Biosciences, Inc. Spatially encoded biological assays
WO2011150284A2 (en) 2010-05-26 2011-12-01 Baxter International Inc. Removal of serine proteases by treatment with finely divided silicon dioxide
AU2010202125B1 (en) 2010-05-26 2010-09-02 Takeda Pharmaceutical Company Limited A method to produce an immunoglobulin preparation with improved yield
WO2012012773A1 (en) * 2010-07-23 2012-01-26 Baxter International Inc. Manufacture of inter -alpha - inhibitor proteins (iaip) from plasma
AU2011364724B2 (en) * 2011-04-08 2016-11-17 Universidad De Costa Rica Method for producing injectable formulations of blood-derived protein materials, and materials obtained using said method
EP2791675B1 (en) 2011-12-13 2018-04-25 Baxalta GmbH Measurement of autoantibodies in low conductivity conditions
TWI629283B (zh) * 2012-02-23 2018-07-11 巴克斯歐塔公司 來自血漿中的免疫球蛋白之ｉ-ｉｖ-１部分沉澱
RU2487725C1 (ru) * 2012-03-15 2013-07-20 Федеральное государственное унитарное предприятие "Научно-производственное объединение по медицинским иммунобиологическим препаратам "Микроген" Министерства здравоохранения Российской Федерации (ФГУП "НПО "Микроген" Минздрава России) Способ получения концентрированного иммуноглобулинового препарата для подкожного введения
CN103197053B (zh) * 2013-03-15 2015-02-18 上海市血液中心 一种抗IgA抗体检测试剂盒
AU2013203043B2 (en) 2013-03-15 2016-10-06 Takeda Pharmaceutical Company Limited Methods to produce a human plasma-derived igg preparation enriched in brain disease-related natural iggs
CN104086642A (zh) * 2014-07-03 2014-10-08 成都蓉生药业有限责任公司 血液制品中fi+iii上清的制备方法
CN104072601A (zh) * 2014-07-03 2014-10-01 成都蓉生药业有限责任公司 血液制品中fii沉淀的制备方法
CN104086646B (zh) * 2014-07-03 2018-10-09 成都蓉生药业有限责任公司 血液制品中fv沉淀的制备方法
GB201413227D0 (en) * 2014-07-25 2014-09-10 Bioproducts Lab Ltd Process
US20170313767A1 (en) 2014-10-21 2017-11-02 The General Hospital Corporation Methods of diagnosis and treatment of tuberculosis and infection
CN204424090U (zh) 2014-11-28 2015-06-24 比亚迪股份有限公司 薄膜电容器
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