HK1142001A1 - Preparation for transnasal application - Google Patents

Preparation for transnasal application

Info

Publication number
HK1142001A1
HK1142001A1 HK10108585.2A HK10108585A HK1142001A1 HK 1142001 A1 HK1142001 A1 HK 1142001A1 HK 10108585 A HK10108585 A HK 10108585A HK 1142001 A1 HK1142001 A1 HK 1142001A1
Authority
HK
Hong Kong
Prior art keywords
preparation
transnasal application
transnasal
application
Prior art date
Application number
HK10108585.2A
Other languages
English (en)
Inventor
Ryoichi Nagata
Shunji Haruta
Original Assignee
Shin Nippon Biomedical Lab Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Shin Nippon Biomedical Lab Ltd filed Critical Shin Nippon Biomedical Lab Ltd
Publication of HK1142001A1 publication Critical patent/HK1142001A1/xx

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0043Nose
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/403Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
    • A61K31/404Indoles, e.g. pindolol
    • A61K31/4045Indole-alkylamines; Amides thereof, e.g. serotonin, melatonin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/41641,3-Diazoles
    • A61K31/41781,3-Diazoles not condensed 1,3-diazoles and containing further heterocyclic rings, e.g. pilocarpine, nitrofurantoin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/4353Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/4375Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a six-membered ring having nitrogen as a ring heteroatom, e.g. quinolizines, naphthyridines, berberine, vincamine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445Non condensed piperidines, e.g. piperocaine
    • A61K31/4523Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
    • A61K31/4535Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a heterocyclic ring having sulfur as a ring hetero atom, e.g. pizotifen
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47Quinolines; Isoquinolines
    • A61K31/485Morphinan derivatives, e.g. morphine, codeine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/56Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • A61K31/573Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone substituted in position 21, e.g. cortisone, dexamethasone, prednisone or aldosterone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605Excipients; Inactive ingredients
    • A61K9/1611Inorganic compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605Excipients; Inactive ingredients
    • A61K9/1629Organic macromolecular compounds
    • A61K9/1652Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/08Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/02Nasal agents, e.g. decongestants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • A61P15/08Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/08Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A61P19/10Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/06Antimigraine agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00Drugs for disorders of the endocrine system
    • A61P5/14Drugs for disorders of the endocrine system of the thyroid hormones, e.g. T3, T4
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841Filling excipients; Inactive ingredients
    • A61K9/4866Organic macromolecular compounds

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Otolaryngology (AREA)
  • Diabetes (AREA)
  • Emergency Medicine (AREA)
  • Rheumatology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Endocrinology (AREA)
  • Inorganic Chemistry (AREA)
  • Reproductive Health (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Pulmonology (AREA)
  • Pain & Pain Management (AREA)
  • Gynecology & Obstetrics (AREA)
  • Pregnancy & Childbirth (AREA)
  • Biomedical Technology (AREA)
  • Obesity (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Hematology (AREA)
  • Hospice & Palliative Care (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
HK10108585.2A 2006-12-26 2010-09-10 Preparation for transnasal application HK1142001A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2006350094 2006-12-26
PCT/JP2007/074787 WO2008078730A1 (ja) 2006-12-26 2007-12-25 経鼻投与用製剤

Publications (1)

Publication Number Publication Date
HK1142001A1 true HK1142001A1 (en) 2010-11-26

Family

ID=39562519

Family Applications (1)

Application Number Title Priority Date Filing Date
HK10108585.2A HK1142001A1 (en) 2006-12-26 2010-09-10 Preparation for transnasal application

Country Status (7)

Country Link
US (2) US8337817B2 (de)
EP (1) EP2116264B1 (de)
JP (2) JP5415769B2 (de)
CN (1) CN101668544B (de)
ES (1) ES2652415T3 (de)
HK (1) HK1142001A1 (de)
WO (1) WO2008078730A1 (de)

Families Citing this family (41)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2224792B1 (es) * 2002-06-28 2007-02-16 Era Plantech, S.L. Produccion de peptidos y proteinas por acumulacion de cuerpos proteicos derivados de reticulos endoplasmico en plantas.
WO2004073729A1 (ja) 2003-02-21 2004-09-02 Translational Research Ltd. 薬物の経鼻投与用組成物
KR100974482B1 (ko) 2003-03-27 2010-08-10 가부시키가이샤 바이오악티스 비강용 분말 약제 투약 장치
US8673360B2 (en) * 2004-08-10 2014-03-18 Shin Nippon Biomedical Laboratories, Ltd. Compositions that enable rapid-acting and highly absorptive intranasal administration
JP5415769B2 (ja) 2006-12-26 2014-02-12 株式会社新日本科学 経鼻投与用製剤
EP2287234B1 (de) * 2008-05-21 2016-03-23 Asahi Kasei Chemicals Corporation Zellulosepulver mit hervorragender vorbeugender abscheidungswirkung und zusammensetzungen daraus
BRPI0912126A2 (pt) * 2008-05-27 2015-11-03 Univ Melbourne método de tratamento de mamíferos com disfunções na trompa de eustáquio
JP5667062B2 (ja) 2008-10-10 2015-02-12 エラ、ビオテック、ソシエダッド、アノニマEra Biotech, S.A. 免疫原特異的アジュバントとしての組換えタンパク粒
WO2010126818A1 (en) * 2009-04-27 2010-11-04 Usworldmeds Llc Intranasal delivery system for dantrolene
WO2010131486A1 (en) * 2009-05-15 2010-11-18 Shin Nippon Biomedical Laboratories, Ltd. Intranasal pharmaceutical compositions with improved pharmacokinetics
WO2011013003A2 (en) * 2009-07-31 2011-02-03 Shin Nippon Biomedical Laboratories, Ltd. Intranasal granisetron and nasal applicator
EP2558120A4 (de) 2010-04-15 2013-08-28 Shin Nippon Biomedical Lab Ltd Verfahren und zusammensetzung zur intranasalen verabreichung
CN103459430B (zh) * 2011-04-06 2016-08-17 陶氏环球技术有限责任公司 生产具有高堆积密度和良好流动性的纤维素衍生物的方法
MX354249B (es) 2011-05-13 2018-02-20 Euro Celtique Sa Formas de dosificación farmacéuticas intranasales que comprenden naloxona.
WO2013059213A1 (en) 2011-10-18 2013-04-25 Amidebio, Llc Chemically and thermodynamically stable insulin analogues and improved methods for their production
BR112014024276A2 (pt) 2012-03-30 2017-08-08 Nuformix Ltd composições de tranilast e co-cristais
US9789071B2 (en) 2012-06-27 2017-10-17 G2B Pharma, Inc. Intranasal formulation of epinephrine for the treatment of anaphylaxis
RU2715714C2 (ru) 2013-03-04 2020-03-03 Безен Хелткэа Люксембург Сарл Сухие фармацевтические композиции, включающие наночастицы активного агента, связанные с частицами носителя
ES2920802T3 (es) * 2013-03-26 2022-08-09 Optinose As Administración nasal
US11554229B2 (en) 2013-03-26 2023-01-17 OptiNose Inc. Nasal administration
US9163073B2 (en) 2013-04-17 2015-10-20 Amidebio, Llc Chemically and thermodynamically stable insulin analogues and improved methods for their production
AU2014315459A1 (en) * 2013-09-03 2016-04-07 G2B Pharma Inc. Intranasal formulation for the treatment of cardiopulmonary resuscitation (CPR), cardiac life support (CLS), anaphylaxis and/or anaphylactoid reactions
ES2904570T3 (es) * 2013-09-24 2022-04-05 Satsuma Pharmaceuticals Inc Formulación de DHE intranasal para el tratamiento del dolor de cabeza
WO2015095644A1 (en) 2013-12-20 2015-06-25 AntiOP, Inc. Intranasal naloxone compositions and methods of making and using same
CN106163499A (zh) * 2014-03-14 2016-11-23 欧皮安特制药有限公司 鼻用药物产品及其使用方法
JP6945614B2 (ja) * 2014-03-26 2021-10-06 オプティノーズ アズ 経鼻投与
MX2016017038A (es) * 2014-06-25 2017-05-01 Optinose As Administracion nasal.
EP3233817B1 (de) 2014-12-19 2020-10-14 Nederlandse Organisatie voor toegepast- natuurwetenschappelijk onderzoek TNO Verbessertes verfahren zur herstellung einer benzolverbindung
CN104474534A (zh) * 2014-12-22 2015-04-01 哈德逊(天津)生物技术有限责任公司 白介素-18抗病毒口腔喷剂
JP2016153391A (ja) * 2015-02-16 2016-08-25 日本合成化学工業株式会社 無水酢酸ナトリウム結晶
EP3316865A4 (de) 2015-07-02 2019-01-23 Civitas Therapeutics, Inc. Triptanpulver zur pulmonalen verabreichung
MX2019001313A (es) * 2016-08-05 2019-09-26 Shin Nippon Biomedical Laboratories Ltd Composiciones farmaceuticas.
US11744967B2 (en) 2017-09-26 2023-09-05 Shin Nippon Biomedical Laboratories, Ltd. Intranasal delivery devices
US20200405983A1 (en) * 2018-02-26 2020-12-31 Shin Nippon Biomedical Laboratories, Ltd. Powder preparation, cartridge, and device
WO2019182745A1 (en) 2018-03-19 2019-09-26 Bryn Pharma, LLC Epinephrine spray formulations
EP3893877A4 (de) 2018-12-11 2022-09-14 Satsuma Pharmaceuticals, Inc. Zusammensetzungen, vorrichtungen und verfahren zur behandlung oder vorbeugung von kopfschmerzen
US11433063B1 (en) 2019-03-12 2022-09-06 Belhaven Biopharma, Inc. Intranasal composition of pharmaceutical countermeasures for chemical warfare nerve agents and accidental exposure to organophosphate pesticides
BR112021021841A2 (pt) * 2019-05-16 2022-01-04 Shin Nippon Biomedical Laboratories Ltd Formulação de pó para administração intranasal, e método de fabricação da mesma
US11400045B2 (en) * 2020-03-16 2022-08-02 Nasus Pharma Ltd. Treatment with powdered intranasal epinephrine
EP4232006A4 (de) * 2020-12-16 2024-05-08 Liw Innovation Ab Neue pulverzusammensetzung
US11617716B2 (en) 2021-06-10 2023-04-04 Belhaven BioPharma Inc. Dry powder formulations of epinephrine and associated methods

Family Cites Families (131)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2224175B1 (de) 1973-04-04 1978-04-14 Isf Spa
IT1017153B (it) * 1974-07-15 1977-07-20 Isf Spa Apparecchio per inalazioni
JPS5420126A (en) 1977-07-12 1979-02-15 Asahi Chem Ind Co Ltd Pharmaceutical composition
JPS53127553A (en) 1977-04-13 1978-11-07 Asahi Chem Ind Co Ltd Vehicle
AU508480B2 (en) * 1977-04-13 1980-03-20 Asahi Kasei Kogyo Kabushiki Kaisha Microcrystalline cellulose excipient and pharmaceutical composition containing thesame
JPS5462328A (en) 1977-10-24 1979-05-19 Asahi Chem Ind Co Ltd Additive for cosmetics
US4226233A (en) * 1978-10-10 1980-10-07 Longevity Products, Inc. Respirators
US4300545A (en) 1980-06-23 1981-11-17 Schering Corporation Method and nozzle for nasal vaccination of immature mammals
JPS5934267A (ja) 1982-08-23 1984-02-24 帝人株式会社 粉状薬剤施薬装置
JPS59163313A (ja) 1983-03-09 1984-09-14 Teijin Ltd 経鼻投与用ペプチドホルモン類組成物
DE3345722A1 (de) * 1983-12-17 1985-06-27 Boehringer Ingelheim KG, 6507 Ingelheim Inhalator
JPS60224616A (ja) 1984-04-24 1985-11-09 Teijin Ltd 経鼻投与用組成物
JPS6242888A (ja) 1985-08-21 1987-02-24 カシオ計算機株式会社 太陽電池を備えたicカ−ド
US5731303A (en) 1985-12-04 1998-03-24 Conrex Pharmaceutical Corporation Transdermal and trans-membrane delivery compositions
JPS63267731A (ja) 1987-04-23 1988-11-04 Asahi Chem Ind Co Ltd 錠剤組成物
CA1336401C (en) 1987-10-15 1995-07-25 Brian H. Vickery Intranasal administration of polypeptides in powdered form
JPH02196719A (ja) 1989-01-24 1990-08-03 Green Cross Corp:The 粉末状医薬組成物
US4947097A (en) 1989-06-12 1990-08-07 The Grass Valley Group, Inc. Automatic switching of motion control with tactile feedback
JP2726177B2 (ja) 1991-08-01 1998-03-11 帝人株式会社 安定化されたカルシトニン類医薬組成物
DK198591D0 (da) * 1991-12-10 1991-12-10 Novo Nordisk As Apparat
US5320094A (en) 1992-01-10 1994-06-14 The Johns Hopkins University Method of administering insulin
US5647345A (en) * 1992-05-12 1997-07-15 Saul; Gilbert D. Respiratory stimulator & methods of use
GB2269992A (en) 1992-08-14 1994-03-02 Rh Ne Poulenc Rorer Limited Powder inhalation formulations
US5417984A (en) 1992-12-14 1995-05-23 Biocontrol, Inc. Low crystallinity cellulose excipients
AU6167894A (en) 1993-01-29 1994-08-15 Miris Medical Corporation Intrapulmonary delivery of hormones
US5672581A (en) 1993-01-29 1997-09-30 Aradigm Corporation Method of administration of insulin
ATE241984T1 (de) 1993-03-26 2003-06-15 Franciscus Wilhelmus He Merkus Pharmazeutische zusammensetzungen zur intranasalen verabreichung von apomorphin
JPH07165613A (ja) * 1993-10-19 1995-06-27 Dot:Kk 経鼻吸収薬物用キャリヤおよび生理活性ペプチド組成物
SE9303574D0 (sv) 1993-11-01 1993-11-01 Kabi Pharmacia Ab Composition for drug delivery and method the manufacturing thereof
JP3414539B2 (ja) 1994-05-11 2003-06-09 有限会社ドット 経鼻吸収用組成物
US5958458A (en) * 1994-06-15 1999-09-28 Dumex-Alpharma A/S Pharmaceutical multiple unit particulate formulation in the form of coated cores
WO1995034582A1 (en) 1994-06-16 1995-12-21 Pharmacia S.P.A. Bioadhesive starches and process for their preparation
JPH0898888A (ja) 1994-09-30 1996-04-16 Teijin Ltd 粉末状薬剤噴霧施薬装置
JP3308419B2 (ja) 1995-02-06 2002-07-29 株式会社ユニシアジェックス 鼻腔用投薬器
JP3308425B2 (ja) 1995-03-10 2002-07-29 株式会社ユニシアジェックス 鼻腔用投薬器
JPH08243164A (ja) 1995-03-13 1996-09-24 Unisia Jecs Corp 鼻腔用投薬器
JP3320261B2 (ja) * 1995-06-01 2002-09-03 株式会社ユニシアジェックス 吸入式投薬器
JP3098401B2 (ja) * 1995-07-12 2000-10-16 株式会社エルティーティー研究所 経鼻投与用製剤
JP3317827B2 (ja) * 1995-10-09 2002-08-26 株式会社ユニシアジェックス 投薬器
JP3197221B2 (ja) * 1996-02-27 2001-08-13 帝人株式会社 吸収性が改善された粉末状経鼻投与組成物
KR100568436B1 (ko) 1996-02-27 2007-04-25 데이진 가부시키가이샤 분말상경비투여조성물
JP3197223B2 (ja) 1996-02-28 2001-08-13 帝人株式会社 即効性と持続性を兼ね備えた粉末状経鼻投与用組成物
JPH09253208A (ja) 1996-03-21 1997-09-30 Unisia Jecs Corp 鼻腔用投薬器
JPH09276405A (ja) 1996-04-15 1997-10-28 Unisia Jecs Corp 鼻腔用投薬器
US5874064A (en) * 1996-05-24 1999-02-23 Massachusetts Institute Of Technology Aerodynamically light particles for pulmonary drug delivery
JP3020141B2 (ja) * 1996-10-07 2000-03-15 株式会社富士薬品 経鼻投与用製剤
GB9700624D0 (en) * 1997-01-14 1997-03-05 Danbiosyst Uk Drug delivery composition
DE69829139T2 (de) * 1997-01-30 2006-04-06 Hitachi, Ltd. Medikator vom ansaugtyp
US6565885B1 (en) 1997-09-29 2003-05-20 Inhale Therapeutic Systems, Inc. Methods of spray drying pharmaceutical compositions
ATE239447T1 (de) 1997-09-29 2003-05-15 Inhale Therapeutic Syst In verneblern verwendbare, stabilisierte zubereitungen
AU9187598A (en) 1997-09-30 1999-04-23 Daiichi Pharmaceutical Co., Ltd. Oral preparation
FR2771012B1 (fr) * 1997-11-17 2000-03-10 Sofab Pulverisateur nasal
JPH11216357A (ja) 1998-02-03 1999-08-10 Tsutsumi Techno Planning Kk 生理活性物質用の吸着担体
JP3530004B2 (ja) * 1998-02-06 2004-05-24 株式会社日立ユニシアオートモティブ 吸入式投薬器
GB9807232D0 (en) 1998-04-03 1998-06-03 Univ Cardiff Aerosol composition
JPH11322582A (ja) * 1998-05-06 1999-11-24 Dot:Kk 経鼻吸収用鼻粘膜付着・滞留型キャリヤ
GT199900061A (es) * 1998-05-15 2000-10-14 Pfizer Formulaciones farmaceuticas.
WO1999062560A1 (en) * 1998-06-05 1999-12-09 Warner-Lambert Company Stabilization of compositions containing ace inhibitors using magnesium oxide
TWI223598B (en) * 1998-06-22 2004-11-11 Pfizer Ireland Pharmaceuticals An intranasal pharmaceutical composition for the treatment of male erectile dysfunction or female sexual disorders, an intranasal delivery system or device and sildenafil mesylate
AU762145C (en) 1998-08-26 2005-03-17 Teijin Limited Powdery pernasal compositions
WO2000012063A1 (fr) 1998-08-26 2000-03-09 Teijin Limited Compositions en poudre s'administrant par voie nasale
ATE347880T1 (de) 1998-10-20 2007-01-15 Univ North Carolina Methoden zum befeuchten der nasenschleimhaut
GB9828721D0 (en) 1998-12-24 1999-02-17 Glaxo Group Ltd Novel apparatus and process
JP2000229859A (ja) 1999-02-12 2000-08-22 Teijin Ltd 安定なブプレノルフィン経鼻製剤
JP2000239187A (ja) 1999-02-22 2000-09-05 Dotto:Kk 経鼻吸収用組成物
US6248363B1 (en) * 1999-11-23 2001-06-19 Lipocine, Inc. Solid carriers for improved delivery of active ingredients in pharmaceutical compositions
JP3912469B2 (ja) 1999-05-13 2007-05-09 セイコーエプソン株式会社 偽造印刷物判定用インク
JP2001055323A (ja) * 1999-08-12 2001-02-27 Teijin Ltd 粉末状経鼻投与用組成物
US6197328B1 (en) * 1999-08-20 2001-03-06 Dott Research Laboratory Nasally administrable compositions
WO2001026630A1 (fr) * 1999-10-12 2001-04-19 Kaken Pharmaceutical Co., Ltd. Preparations pour inhalation en poudre et leur procede de production
DE10049392A1 (de) 1999-10-14 2001-04-19 Becton Dickinson Co Flüssigkeits-Ausgabevorrichtung
GB9925934D0 (en) 1999-11-03 1999-12-29 Glaxo Group Ltd Novel apparatus and process
JP2003535042A (ja) * 2000-01-20 2003-11-25 バジリア ファルマスーチカ アーゲー 鼻腔に投与可能な環式ペプチド組成物
NZ517693A (en) * 2000-06-12 2003-09-26 Teijin Ltd Powder medicine multiple dose administration device
DE10031043A1 (de) 2000-06-26 2002-02-14 Bayer Ag Retardzubereitungen von Chinolonantibiotika und Verfahren zu ihrer Herstellung
CA2423469A1 (en) 2000-10-18 2002-04-25 Massachusetts Institute Of Technology Methods and products related to pulmonary delivery of polysaccharides
US6595210B2 (en) 2000-11-27 2003-07-22 Unisia Jecs Corporation Inhalator for administering powder composition
JP2002255795A (ja) 2001-02-26 2002-09-11 Teijin Ltd 経鼻投与用組成物
WO2002094233A1 (en) 2001-05-24 2002-11-28 Alexza Molecular Delivery Corporation Delivery of antiemetics through an inhalation route
MXPA03005980A (es) * 2001-07-05 2003-09-10 Translational Res Ltd Composiciones para administracion nasal de insulina.
WO2003024396A2 (en) 2001-09-17 2003-03-27 Glaxo Group Limited Dry powder medicament formulations
DE60222160T2 (de) 2001-10-12 2008-06-12 Elan Pharma International Ltd., Athlone Zusammensetzungen mit einer kombination aus eigenschaften sofortiger freisetzung und kontrollierter freisetzung
JP3975327B2 (ja) 2001-11-19 2007-09-12 株式会社 バイオアクティス 鼻腔用粉状薬剤施薬装置
WO2003045357A1 (en) 2001-11-27 2003-06-05 Transform Pharmaceuticals, Inc. Oral pharmaceutical formulations comprising paclitaxel, derivatives and methods of administration thereof
JP2003175103A (ja) 2001-12-12 2003-06-24 Teijin Ltd 粉末薬剤多回投与器
FR2834212B1 (fr) * 2001-12-27 2004-07-09 Besins Int Belgique Utilisation d'une poudre a liberation immediate dans des compositions pharmaceutiques et nutraceutiques
JP4212019B2 (ja) * 2002-01-09 2009-01-21 Translational Research 株式会社 薬物の経鼻投与用組成物
EP1487407A4 (de) 2002-03-12 2010-08-25 Microdose Therapeutx Inc Situsspezifische abgabe von gleichzeitig verabreichten arzneimitteln durch inhalation
US20030199424A1 (en) 2002-03-20 2003-10-23 Smith Maree Therese Method of treatment and/or prophylaxis
JP3950738B2 (ja) 2002-05-14 2007-08-01 株式会社 バイオアクティス 鼻腔用粉状薬剤施薬装置
PT1531794T (pt) 2002-06-28 2017-09-14 Civitas Therapeutics Inc Epinefrina inalável
US7115281B2 (en) 2002-07-08 2006-10-03 Ranbaxy Laboratories Limited Processes for the preparation of oral dosage formulations of modafinil
GB0215904D0 (en) 2002-07-09 2002-08-21 Team Holdings Uk Ltd Drug delivery system and method
US6855913B2 (en) 2002-08-06 2005-02-15 Hobart Brothers Company Flux-cored wire formulation for welding
GB2395900A (en) 2002-12-04 2004-06-09 Elan Drug Delivery Ltd Therapeutic composition for respiratory delivery
GB0228826D0 (en) * 2002-12-11 2003-01-15 Okpala Joseph Hair technology in creating particles with improved delivery capabilities
US20040173211A1 (en) * 2003-01-14 2004-09-09 Boehringer Ingelheim International Gmbh Powder inhaler
RU2345791C2 (ru) 2003-01-31 2009-02-10 Орексо Аб Быстродействующая фармацевтическая композиция
WO2004073729A1 (ja) * 2003-02-21 2004-09-02 Translational Research Ltd. 薬物の経鼻投与用組成物
JP4136724B2 (ja) 2003-03-05 2008-08-20 株式会社日立製作所 鼻腔用投薬器
EP1605858A1 (de) 2003-03-21 2005-12-21 Alfred Schmid AG Gossau Mischkapsel
KR100974482B1 (ko) * 2003-03-27 2010-08-10 가부시키가이샤 바이오악티스 비강용 분말 약제 투약 장치
WO2004110492A2 (en) 2003-06-06 2004-12-23 Glaxo Group Limited Composition comprising triptans and nsaids
WO2004112702A2 (en) 2003-06-13 2004-12-29 Advanced Inhalation Research, Inc. Low dose pharmaceutical powders for inhalation
US20050042177A1 (en) 2003-07-23 2005-02-24 Elan Pharma International Ltd. Novel compositions of sildenafil free base
EP1671667A4 (de) 2003-10-09 2013-05-01 Shin Nippon Biomedical Lab Ltd Abgabevorrichtung für ein pulverförmiges medikament für die nasenhöhle
GB0328186D0 (en) * 2003-12-05 2004-01-07 West Pharm Serv Drug Res Ltd Intranasal compositions
US8545881B2 (en) 2004-04-19 2013-10-01 Eurand Pharmaceuticals, Ltd. Orally disintegrating tablets and methods of manufacture
JP2007534693A (ja) * 2004-04-23 2007-11-29 サイデックス・インコーポレイテッド スルホアルキルエーテルシクロデキストリンを含有するdpi製剤
US8673360B2 (en) * 2004-08-10 2014-03-18 Shin Nippon Biomedical Laboratories, Ltd. Compositions that enable rapid-acting and highly absorptive intranasal administration
AU2005291427A1 (en) 2004-10-06 2006-04-13 Boehringer Ingelheim International Gmbh Dispensing device, storage device and method for dispensing powder
CA2583101A1 (en) * 2004-10-15 2006-04-20 Pfizer Products Inc. Compositions and methods for intranasal, buccal, sublingual and pulmonary delivery of varenicline
GB0425758D0 (en) * 2004-11-23 2004-12-22 Vectura Ltd Preparation of pharmaceutical compositions
US7036787B1 (en) * 2005-02-04 2006-05-02 Taiwan Thick-Film Ind. Corp. Display strut adjusting structure
WO2007019229A1 (en) * 2005-08-05 2007-02-15 3M Innovative Properties Company Compositions exhibiting improved flowability
US8591457B2 (en) 2005-08-10 2013-11-26 Alza Corporation Method for making a needle-free jet injection drug delivery device
ES2308750T3 (es) 2005-08-29 2008-12-01 Teva Pharmaceutical Industries Ltd Tadalafil en particulas solidas que presenta una distribucion de particulas bimodal.
JP4841564B2 (ja) * 2005-12-06 2011-12-21 旭化成ケミカルズ株式会社 高速直接打錠による錠剤の製造方法
WO2007089247A1 (en) 2006-01-31 2007-08-09 Teva Pharmaceutical Industries Ltd. Oxcarbazepine pharmaceutical formulation and its method of preparation, wherein oxcarbazepine has a broad and multi-modal particle size distribution
TW200811104A (en) 2006-04-25 2008-03-01 Theravance Inc Crystalline forms of a dimethylphenyl compound
US7806117B2 (en) 2006-06-07 2010-10-05 Shin Nippon Biomedical Laboratories, Ltd. Peroral powder delivery device
EP2068831A4 (de) 2006-07-28 2010-07-21 Novadel Pharma Inc Antimigräne-mundspray-formulierungen und entsprechende verfahren
US20080029084A1 (en) 2006-08-04 2008-02-07 Nastech Pharmaceutical Company Inc. Device for improved peptide delivery
AR062741A1 (es) 2006-09-07 2008-12-03 Hirsh Andrew J Metodo para aumentar la hidratacion de la mucosa y la evacuacion de l a mucosa mediante tratamiento con bloquadores de los canales del sodio y osmolitos
GB0625322D0 (en) 2006-12-19 2007-01-24 Pharmakodex Ltd Pharmaceutical compositions
JP5415769B2 (ja) 2006-12-26 2014-02-12 株式会社新日本科学 経鼻投与用製剤
GB2448183A (en) 2007-04-05 2008-10-08 Optinose As Nasal powder delivery device
CA2702261A1 (en) 2007-10-12 2009-04-16 Map Pharmaceuticals, Inc. Inhalation drug delivery
WO2009095684A1 (en) 2008-02-01 2009-08-06 Vectura Limited Pulmonary formulations of triptans
WO2010131486A1 (en) 2009-05-15 2010-11-18 Shin Nippon Biomedical Laboratories, Ltd. Intranasal pharmaceutical compositions with improved pharmacokinetics
WO2011013003A2 (en) 2009-07-31 2011-02-03 Shin Nippon Biomedical Laboratories, Ltd. Intranasal granisetron and nasal applicator

Also Published As

Publication number Publication date
JP2014028848A (ja) 2014-02-13
CN101668544A (zh) 2010-03-10
US8337817B2 (en) 2012-12-25
JP5415769B2 (ja) 2014-02-12
US20130095145A1 (en) 2013-04-18
WO2008078730A1 (ja) 2008-07-03
EP2116264A4 (de) 2012-01-18
JPWO2008078730A1 (ja) 2010-04-30
US10195139B2 (en) 2019-02-05
US20100178331A1 (en) 2010-07-15
CN101668544B (zh) 2013-04-24
US20150017212A9 (en) 2015-01-15
EP2116264B1 (de) 2017-09-27
EP2116264A1 (de) 2009-11-11
ES2652415T3 (es) 2018-02-02

Similar Documents

Publication Publication Date Title
HK1142001A1 (en) Preparation for transnasal application
GB0602424D0 (en) Compounds
GB0602046D0 (en) Compounds
GB0605786D0 (en) Compounds
EP2116535A4 (de) Glucokinase aktivierende substanz
EP1984379A4 (de) Anti-arenavirale verbindungen
GB0605785D0 (en) Compounds
GB0605784D0 (en) Compounds
EP2082022A4 (de) Verbindungen
GB0602042D0 (en) Compounds
EP2004174A4 (de) Naphthalendionverbindungen
EP1973905A4 (de) Verbindungen
AP2009004767A0 (en) Cubstituted azolin-2-yl-amino compounds
EP2016069A4 (de) Bispyridiniumverbindungen
GB0602560D0 (en) Compounds
GB0602412D0 (en) Compounds
GB0600427D0 (en) Compounds
HU0600193V0 (en) Latch-cover for water-network
PL380476A1 (pl) Preparat farmaceutyczny
GB0609547D0 (en) My Gogglebox
GB0602454D0 (en) Compounds
GB0604377D0 (en) Compounds
GB0602451D0 (en) Compounds
GB0602134D0 (en) Compounds
GB0602455D0 (en) Compounds